060 - CRISPR, Wellness Tech Warnings, and the Brain's Fountain of Youth - HealthHippieMD Week In Review

More on the Impact of AI on Science

More on how AI is revolutionizing science in the Economist: How scientists are using artificial intelligence (gift article) and Could AI transform science itself? (gift article).

CRISPR and the Microbiome

CRISPR pioneer and Nobel Prize winner Jennifer Doudna is focusing on the microbiome: Crispr Pioneer Jennifer Doudna Has the Guts to Take On the Microbiome | WIRED. I highly recommend Walter Isaacson's biography on Doudna: The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race.

Big Tobacco Stains the Food Industry

"In a broader and much less restricting sense," an executive wrote, "R.J. Reynolds is in the flavor business." Although Big Tobacco is no longer in the food business, they left a terrible legacy: Many junk foods today were made and marketed by Big Tobacco - The Washington Post. (gift article)

Is Junk Food Addictive?

Recent studies suggest highly processed foods may have addictive qualities akin to drugs. Rats opt for sugar over cocaine, even enduring electric shocks for the sweet treat. Humans display similar behavior, consuming processed foods to the point of vomiting and diarrhea post-bariatric surgery. Daily snacking on these foods can rewire our brain's reward circuits, mirroring the cravings induced by cocaine. "In 2022, scientists published an opinion piece in the journal Addiction arguing that highly processed foods should be classified as addictive based on a 1988 Surgeon General report on tobacco products." Food Can Be Literally Addictive, New Evidence Suggests - Scientific American.

Healthy Diet Lowers Dementia Risk

Wapo had an article on the importance of diet in staving off dementia. Recent studies suggest the benefits occur even when started later in life: Eating heart-healthy foods also helps lower your dementia risk - The Washington Post. (gift article)

PANDA-monium: Infections Unmask Childhood Psychiatric Illnesses

Many doctors remain unaware PANDAS (Paediatric Autoimmune-Neuropsychiatric Disorders Associated with Streptococcus and its counterpart, PANS (Paediatric Acute-onset Neuropsychiatric Syndrome), or dismiss them as fictitious. This ignorance results in misdiagnoses, inappropriate treatments, and even parental accusations. Recent research suggests these disorders stem from an autoimmune reaction post-infection. The changing perception may have broader implications for understanding infections' roles in psychiatric conditions (for both children and adults), offering hope for early intervention and effective treatment. How common infections can spark psychiatric illnesses in children. (gift article)

Plasma, Platelets, and PF4: Searching for the Brain's Fountain of Youth

Groundbreaking research in mice may have revealed a key to rejuvenating aging brains. Neuroscientists have uncovered that platelets, specifically a group of molecules called Platelet Factor 4 (PF4), play a vital role in the age-reversal process. Three interventions—transfusions of young blood, the hormone klotho, and physical exercise—all harness PF4 to deliver their benefits to the brain. When 22-month-old mice were injected with young blood plasma or PF4, their cognitive age reversed dramatically. These findings, independently discovered by three research teams, offer new hope for combating age-related cognitive decline and unlocking the secrets of brain rejuvenation. Scientists uncover how young blood rejuvenates aging brains | BBC Science Focus Magazine.

Animal Communication Unveils Surprising Parallels to Human Language

Researchers are uncovering fascinating connections between animal communication and human language. For years, the belief in an unbridgeable gap between human language and animal communication prevailed. However, recent studies challenge this notion, revealing that various species possess intricate vocal learning abilities, from mice to dolphins. These findings suggest that language-related capacities may exist on a continuum across the animal kingdom. Scientists are now delving deeper into deciphering the meanings and intricacies of animal communication, shedding light on the evolution of language and our shared cognitive landscapes with other creatures. The Animals Are Talking. What Does It Mean? - The New York Times. (gift article)

+How AI is being leveraged to decode animal communication: Can We Talk to Whales? | The New Yorker and ‎Unexplainable: Can we talk to animals? on Apple Podcasts.

When the CIA, Artificial Intelligence, and Healthcare Collide

Palantir's Reputation Stalks Its Bid for the UK's National Health Data | WIRED is an interesting article about how Peter Thiel's big data analytics company (and surveillance government contractor), Palantir, is courting Britain's National Health Service for access to their data. What possibly could go wrong?

Big Tech Knows Your Most Intimate Health Details

Your most intimate health details have become data points in the digital realm. Tech giants, often unbeknownst to users, accumulate a treasure trove of personal health information through online interactions, from therapy sessions to fitness apps. Recent cases, like BetterHelp's data-sharing debacle, have exposed the extent of this information harvesting, raising concerns about privacy violations and potential harm. While some believe federal laws like HIPAA shield health data, the truth is more complicated. A fragmented regulatory landscape, limited enforcement resources, and the rapid evolution of technology call for comprehensive data privacy legislation to keep pace with the digital age. What Big Tech Knows About Your Body - The Atlantic.

Build a Real Music Collection

This author cites why she owns her music collection and eschews streaming: Want to Enjoy Music More? Stop Streaming It. - The New York Times. (gift article)