A lecture I gave last week.
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A healthy microbiome is a diverse microbiome. One of the substances up-regulated in those with the healthiest microbiomes is short-chain fatty acids (SCFAs). SCFAs influence gut health directly by acting as food for the cells lining the gastrointestinal tract and by tightening the junctions between cells, but SCFAs are also are increasingly associated with a wide range of systemic health benefits. These benefits include improved immunologic function, lower systemic inflammation, and anti-cancer effects. Individuals with the highest level of SCFAs tend to have the healthiest and most diverse gut flora.
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Probiotics are all the rage. But a recent article in the Wall Street Journal, Those Probiotics May Actually Be Hurting Your ‘Gut Health’, drove home a point I often try to make about prebiotics and probiotics.
Probiotics contain live, microscopic organisms. Yogurt, Kefir, Kimchi, Sauerkraut, and other fermented foods have live bacterial strains. The type of bacteria and yeast often vary by brand. Prebiotics contain no live organisms. Instead, they are substances that humans cannot digest. The substances instead feed the beneficial bacteria of our gut (e.g., psyllium or inulin).
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