Writing

077 - Art's Heart, Genes to Screens, and the Neuroscience of Creativity - HealthHippieMD Week In Review

Genes to Screens

In 2017, the East Bay Regional Park District Police Department turned to Parabon NanoLabs to help solve the 1990 murder of Maria Jane Weidhofer. Parabon, using DNA from the crime scene, created a 3D model of the potential suspect's face, a process known as DNA phenotyping. This method predicts physical features based on genetic attributes, although its accuracy and scientific validity are debated. Controversially, a detective later attempted to use facial recognition technology on this DNA-generated image, a move criticized by civil liberties experts and contrary to Parabon NanoLabs' terms of service. This attempt underscores the growing concern over the misuse of technology in law enforcement, particularly the blending of unproven methods that could lead to misidentification and potential miscarriages of justice. Despite these concerns, several police departments are interested in combining these technologies, citing the potential benefits of cold cases. However, experts like Jennifer Lynch from the Electronic Frontier Foundation argue that such practices are based on "junk science" and pose significant risks of falsely identifying suspects. Cops Used DNA to Predict a Suspect's Face—and Tried to Run Facial Recognition on It | WIRED.

The Slate article A simple trick to get over impostor syndrome offers insight into overcoming impostor syndrome, where individuals doubt their achievements and fear being exposed as frauds. The author, a psychologist, suggests shifting from seeing oneself as an expected expert to embracing a "voyager" role in one's professional journey. This approach encourages continuous learning, adaptability, and acceptance of mistakes as part of growth. It alleviates the pressure to be perfect, aligning with qualities valued by employers and fostering a balance of confidence and humility. This mindset shift enables personal and professional development without the burden of impostor syndrome.

NCCIH on Bodybuilding and Performance Enhancement

Resistance training is integral to one's exercise regimen at any age. The National Center on Complementary and Integrative Health has a health information page on enhancement supplements: Bodybuilding and Performance Enhancement Supplements | NCCIH.

Neuroscience's Secrets to Creativity

"Find what you love and let it kill you." I love that quote when thinking about one's passions (although the original context was about alcohol addiction). How the "salience network" can unleash your creativity - Big Think delves into how breaking free from conventional thought processes can lead to significant creative breakthroughs, a concept supported by neuroscience. It highlights historical examples like Archimedes and Isaac Newton, who achieved their eureka moments not through relentless analysis but by stepping away from their habitual cognitive patterns. The brain's "salience network" plays a pivotal role in this process, signaling when things deviate from the norm and allowing for a fresh perspective. Essentially, the first step towards innovation is to move away from the "House of Habit." The article emphasizes that this ability to disrupt the default mode network (DMN) and embrace new sensory inputs isn't just for geniuses but is an intrinsic part of the human brain, helping to foster creativity and problem-solving in various fields.

Reflective Resolutions

The article, Five Questions to Ask Yourself Every Evening, explores the importance of self-reflection to understand our daily barrage of thoughts and emotions. It suggests that our minds, busy with a constant stream of ideas and feelings, often repress these thoughts, leading to potential mental health issues. To address this, the article proposes five introspective questions to help identify true worries, sadness, annoyances, bodily needs, and joys. This practice, inspired by Socrates' emphasis on self-knowledge, aims to bring peace and clarity to our minds, fostering a more joyful and balanced life. (Thanks, Allyssa)

The Write Way to Think

I've used journaling for years to clarify my thinking. The article How to Use Writing to Sharpen Your Thinking delves into how writing remains a vital tool for sharpening our intellectual abilities, even in the age of advanced AI. An influential venture capitalist and essayist, Paul Graham, emphasizes that writing is integral to clear thinking and understanding. In his article "Putting Ideas into Words," Graham notes that writing about a topic reveals gaps in one's knowledge, leading to more precise and complete ideas. Another Silicon Valley notable, Tim Ferriss, concurs and offers practical advice on enhancing thinking through writing. He suggests writing anything regularly, focusing on editing and re-editing to refine thoughts. Ferriss also recommends seeking feedback, particularly highlighting the "ten percent rule," where readers identify the most crucial parts of the writing. This process, he argues, is not just for aspiring writers but for anyone who wants to maintain mental sharpness in their pursuits. Graham's pithy tweet encapsulates the essence: "Reading won't be obsolete till writing is, and writing won't be obsolete till thinking is."

Art's Heart: Reviving Our Cultural Pulse

David Brook's excellent Opinion | How Art Creates Us - The New York Times (gift article) discusses the decline in cultural engagement in society and its impact on human empathy and character. Brooks advocates for the transformative power of art and culture, emphasizing their role in enriching emotional intelligence and understanding. He highlights how cultural experiences, like those of novelist Alice Walker, deepen connections and broaden perspectives. Arguing that society's increasing malaise partly stems from a cultural disconnect, Brooks urges a re-embrace of the humanities to enhance personal growth and societal well-being, underscoring the moral and emotional enrichment the arts provide.

Bitter Buzz - Caffeine's Dirty Little Secret

Panera's Charged Lemonade, introduced in 2022, has sparked controversy with its high caffeine content, leading to lawsuits and health concerns. Containing more caffeine than standard energy drinks, it's implicated in wrongful death cases and health issues. Panera responded by adding warnings, reducing caffeine levels, and limiting access. This situation reignites the complex debate on safe caffeine limits. Symptoms of excessive intake, known as caffeinism, include severe health risks. With varying individual tolerances and an array of highly caffeinated products available, the article underscores the challenge of regulating and understanding safe caffeine consumption. Caffeine’s Dirty Little Secret - The Atlantic (thanks, Diana).

052 - Genetic Judo, Young Blood, and Gray Hair - HealthHippieMD Week In Review

Age is Just a Number

As seniors face complex health decisions, age alone may not be the best guide. Medical associations and health groups are shifting to consider life expectancy when recommending screenings and treatments. With the average life expectancy of a 75-year-old being 12 years, online tools like the "Know Your Chances" calculator can estimate mortality and disability risks, providing valuable context beyond age. By incorporating factors like smoking history and health status, patients can make more informed decisions about their healthcare, ultimately improving outcomes and avoiding unnecessary treatments. A Number That Should Guide Your Health Choices (It's Not Your Age) - The New York Times (gift article)

Immune System Influences Behavior

A recent study found the immune system (at least in mice) plays a role in altering our behaviors, especially in response to allergic triggers. "We find immune recognition controls behavior, specifically defensive behaviors against toxins that are communicated first through antibodies and then to our brains." Our Immune System May Help Guide Behavior

Humata.AI: ChatGPT to Query Academic Manuscripts

If you rely on academic publications for your work, prepare to have your mind blown. With Humata.AI,, after uploading a pdf of a manuscript, you can ask questions about the content or ask questions about a folder full of articles in aggregate. It worked incredibly well in the manuscripts I tried. My only complaint about this nascent tool was the limited ways to interact with the content, but I'm sure features will expand as the tool matures. Humata.ai worked much better in my experimentation than another tool I tried, Liquidtext. I suspect the field will get increasingly crowded with science-aware chatbots. Humata.AI is free for the first 60 pages of content, $15/month for more.

Using ChatGPT to Improve Your Writing

Large Language Models, like ChatGPT, are helpful in various ways for writing. Here are some ideas: 5 Ways ChatGPT Can Improve, Not Replace, Your Writing +And here is an article about using ChatGPT in medical diagnosis: A Mystery in the E.R.? Ask Dr. Chatbot for a Diagnosis.

Yo-Yo Diet Industry's Latest Spin

The weight loss industry is witnessing a new wave of reinvention as Americans continue their yo-yo relationship with dieting. Diet apps like Noom and WW (formally WeightWatchers) are now adopting a psychological approach to weight loss, emphasizing self-acceptance and joyful movement. Recently, Noom and WeightWatchers have integrated GLP-1 obesity drugs like Ozempic into their services, acknowledging that medications can be crucial in achieving good health for many. This shift reflects the desire to lose weight, though the approach has evolved from moralizing to a more attainable, value-neutral goal. The Diet Industry Is Pivoting to Ozempic

Unraveling the Mystery Behind Graying Hair

Gray hair is a visible example of how genetics and aging interact. Hair gets its color from melanin, a natural pigment produced by melanocytes. As we age, stem cell melanocytes can become trapped, leading to gray hair. Stress may also play a role in graying. While there's no reliable way to prevent or reverse gray hair, recent research suggests some intriguing possibilities. Why Does Our Hair Turn Gray? The Science of Aging Hair, Explained

Health System Monopolies

The NY Times published an opinion piece on healthcare monopolies: Opinion | The Ridiculous Medical Bill Brought to You by the Latest Hospital Merger - The New York Times (gift article). Hospital mergers and consolidations have created monopolies in the healthcare system, leading to decreased patient choice, rising prices, and limited innovation. The Biden administration has attempted to address the issue with antitrust activity, but hospital mergers have proven harder to curb compared to other industries. The Federal Trade Commission faces challenges blocking hospital mergers due to lengthy analysis and limited resources. Vertical mergers, where extensive hospital systems acquire smaller ones or doctors' practices, further exacerbate price increases. States are now considering price regulation as a possible solution to rein in the power of giant health systems.

Learning on Vacation

In this article, Arthur C. Brooks explores a vacation model often overlooked—turning leisure into learning. Research suggests that pursuing intrinsic interests and learning something new enhances well-being, even if it involves some sacrifice. By focusing on activities that captivate our curiosity, like taking a class or engaging in a guided retreat, vacations can be transformed into rewarding and content-filled experiences. So, instead of conventional models, consider turning your time off into an opportunity for personal growth and happiness. How to Have Your Most Fulfilling Vacation Ever

Young Blood Slows Aging (in Mice)

In a groundbreaking study, scientists extended the lifespans of older mice by connecting their blood vessels to younger mice, resulting in a 6 to 9 percent longer life for elderly rodents. Though not an anti-aging treatment for humans, the research suggests that compounds present in the blood of young mice may promote longevity. The experiment involved parabiosis, joining the animals together for an extended period, and upon separation, the aging process of the older mice appeared to have reversed, making them biologically "younger." Blood of Young Mice Extends Life in the Old - The New York Times (gift article)

Genetic Judo

"It's very cool. It turns something the cancer cell needs to stay alive into something that kills it, like changing your vitamin into a poison." Scientists at Stanford have developed a novel molecule that could potentially lead to groundbreaking cancer drugs. The molecule links cancer-driving proteins to cell-death genes, effectively turning the molecules promoting deadly growth into self-destruction triggers. In lab experiments, this dumbbell-shaped molecule was successful in activating cell-death genes in a blood cancer, diffuse large B-cell lymphoma. Flipping a Switch and Making Cancers Self-Destruct - The New York Times (gift article)