ChatGPT

118 - Kindness, Humor, and Maple Syrup - HealthHippieMD Week In Review

Small Acts, Big Ripples

An upward spiral – how small acts of kindness and connection really can change the world, according to psychology research explores how small, intentional acts of kindness and connection can catalyze societal change. Drawing on psychology, the author highlights how collective “micro-activism” combats hopelessness by addressing cognitive dissonance and fostering empathy. Studies reveal that personal connections soften prejudices, shift attitudes, and strengthen communities, ultimately influencing societal structures. From bridging political divides to improving intergroup relations, Hinchey demonstrates the transformational potential of everyday compassion. By building intentional relationships, individuals spark a powerful “upward spiral” of positive change, proving that small actions can create impactful global ripples.

Why Humor Is Serious Business

According to psychologists, humor serves as an unconscious yet strategic coping mechanism, transforming stress into moments of joy and connection. By triggering laughter, it enhances creativity, broadens perspective, and offers physical benefits like improved breathing and relaxation. Socially, humor fosters bonds, yet it requires mindful application—misplaced or mean-spirited jokes can deepen divides. Experts caution against toxic positivity, suggesting humor be used in moderation, providing emotional reprieve while still processing life’s challenges. Ultimately, humor acts as a psychological balm, equipping us with “antibodies” to weather hard times.How Humor Can Help You Get through Hard Times | Scientific American.

The Science of Chuckles and Tickles

A study by Roza Kamiloglu at the Free University of Amsterdam identifies two core types of human laughter: tickling-induced and laughter sparked by everything else. Using 887 video samples and machine learning, researchers found that tickling laughter has unique acoustic traits that make it more recognizable, a feature possibly tied to its evolutionary roots in primate play and bonding. Unlike other laughter forms, which evolved later with human cognition, tickling laughs date back over 10 million years. These findings illuminate laughter’s role in social connection and its potential infectiousness. The two types of human laugh.

Sweet or Sour? The Truth About Sugar Substitutes

As consumers seek to reduce sugar intake, food manufacturers increasingly use artificial and natural sugar substitutes, such as stevia, monk fruit, and allulose, to meet demand. While these alternatives promise fewer calories, experts caution about their health implications. Research links artificial sweeteners to potential risks, including cancer, heart disease, diabetes, depression, and gut health issues. New “natural” substitutes may seem safer, but their long-term effects remain uncertain. Moderation is key, with experts advising reduced reliance on processed foods and careful label scrutiny to limit hidden sweeteners. Ultimately, a balanced diet of whole foods is the safest choice. Are newer sugar substitutes better for you than artificial sweeteners? - The Washington Post (gift article).

Sweet Benefits of Maple Syrup for Health

A clinical trial (partially sponsored by the Maple Syrup Industry) reveals that swapping refined sugars for maple syrup improves cardiometabolic health, reduces abdominal fat, and enhances gut microbiota. Published in The Journal of Nutrition, the study highlights maple syrup’s natural compounds, including anti-inflammatory polyphenols, which lower blood sugar, systolic blood pressure, and harmful gut bacteria while increasing beneficial strains. Participants consuming two tablespoons daily experienced notable health improvements over eight weeks. Researchers aim to expand these findings, solidifying maple syrup as a “smarter sweetener” and an effective tool in preventing metabolic diseases like diabetes and cardiovascular issues. Reducing Abdominal Fat: Researchers Uncover Surprising Health Benefits of Maple Syrup. (Thanks, Amy!).

How Fear Shapes Your Choices

Loss aversion, a cognitive bias rooted in human psychology, compels us to avoid losses rather than seek equivalent gains, often leading to risk aversion and suboptimal decisions. Stemming from evolutionary survival mechanisms, this bias influences various aspects of life, from investments to career choices. How Loss Aversion Controls Your Decisions Without You Knowing It explores its impact on decision-making, highlighting cases like Polaroid’s failure to adapt and the sunk cost fallacy’s grip. Strategies to counteract loss aversion include reframing outcomes, quantifying risks, conducting pre-mortem analyses, and building emotional resilience, enabling more balanced, growth-oriented decisions.

Brain Gains with a Little Strain

A Penn State study reveals that even light physical activity, such as walking or playing, can enhance cognitive processing speed, reversing four years of cognitive aging. By tracking 204 middle-aged adults through smartphone check-ins over nine days, researchers found mental speed improved after participants engaged in any physical activity, regardless of intensity. The findings suggest movement, not vigorous exercise, as the key to cognitive boosts. While the long-term effects remain uncertain, ongoing research aims to explore how daily habits influence brain health and dementia prevention, using cutting-edge digital tools to deepen understanding. Light exercise can yield significant cognitive benefits, new research shows.

ChatGPT Diagnoses Better than Doctors

A study revealed ChatGPT’s diagnostic prowess surpassed physicians, even when doctors used the chatbot. While ChatGPT achieved a 90% accuracy rate on medical case histories, doctors averaged 74-76%, highlighting overconfidence and underutilization of AI. Researchers noted doctors often disregarded ChatGPT’s insights, contradicting their initial assumptions. The findings underscore the untapped potential of AI as a “doctor extender,” emphasizing the need for better integration and training. Though AI’s linguistic models shine in diagnosis, the human-AI collaboration still faces hurdles rooted in trust and adaptation to technology’s full capabilities. ChatGPT Defeated Doctors at Diagnosing Illness - The New York Times (gift article).

Keep Calm and Carry On (Mindfully)

How to Stay Calm When the World Is in Chaos | Psychology Today, although written in 2020, is equally applicable today. The article explores strategies for maintaining composure in an increasingly chaotic world. It emphasizes acknowledging fear without letting it dominate, living with intention, and fostering inner peace. Suggestions include limiting exposure to anxiety-inducing news, setting boundaries with people who amplify distress, and taking small, meaningful actions to feel empowered. The piece highlights the role of mindfulness, particularly meditation, as a tool to anchor oneself in the present and reduce catastrophizing thoughts. Seeking support from trusted individuals or professionals is encouraged, reinforcing that while change is inevitable, inner resilience can help navigate uncertainty.

Tune Up Your Memories

Listening to music can change how you remember past events - The Washington Post (gift article) reveals how music can remix your memories, shifting their emotional tone. Research from the Georgia Institute of Technology shows that listening to emotionally charged music during memory recall can reshape how those moments are remembered. Brain scans revealed enhanced activity in emotional and memory-processing regions, suggesting music’s power to intertwine with and reframe past events. These findings open new possibilities for music-based therapies, particularly for PTSD and depression. Everyday soundtracks, too, might uplift your mood and subtly transform how you recall life’s moments in the future.

082 - AI Emotional Surveillance, Ibogaine, and the Microbiome of Death - HealthHippieMD Week In Review

NCCIH Guide to Yoga

Yoga is an ancient and complex practice rooted in Indian philosophy. It began as a spiritual practice but has become popular to promote physical and mental well-being. Here is the evidence behind its health benefits: Yoga: What You Need To Know | NCCIH

Daily Uses of ChatGPT

Here is an excellent set of suggestions for using ChatGPT to make your life easier. 10 ways to use ChatGPT in daily life

Baking End-of-Life Conversations into Family Gatherings

How to Make End-of-Life Planning Less Stressful - The New York Times (gift article) explores the importance of end-of-life planning, inspired by the author's family unconventional approach to discussing the topic over a meal. Despite initial reluctance, the gathering provided clarity and comfort, revealing unexpected preferences like her parents' desire to avoid memorial services and her sister's wish for a Starbucks-held ceremony. The article emphasizes the need for open communication, preparation, and regular check-ins to ensure loved ones' wishes are respected and to alleviate future stress. It serves as a reminder that addressing end-of-life matters can be a gift to family members, sparing them from guesswork and chaos during grief.

Microbes Clock In to Solve Mysteries of Death

Scientists have uncovered a consistent network of microbes in decomposing human corpses, regardless of location or climate. By studying 36 cadavers across different environments, researchers found that these critical decomposers, comprising about 20 types of bacteria and fungi, appear predictably during the first 21 days of decomposition. This discovery has the potential to revolutionize forensic science, as tracking the abundance and patterns of these microbes can help estimate the time since death with high accuracy. This microbial clock could be a valuable tool in forensic investigations, providing a more precise determination of the postmortem interval (PMI). However, further research is needed to apply these findings in real-world scenarios, especially in cases where bodies are buried or submerged, which can alter the decomposition process. 'Microbiome of Death' Uncovered on Decomposing Corpses Could Aid Forensics | Scientific American

Sleep Engineering

Recent studies suggest that manipulating sleep could offer novel treatments for mental health issues and memory loss. Techniques like "imagery rehearsal" therapy and sleep-engineering devices aim to reshape nightmares and enhance positive memories during sleep. Researchers have found that pairing specific sounds with positive imagery before sleep and replaying those sounds during REM sleep can reduce the frequency of nightmares and improve overall mood. This approach leverages the brain's ability to consolidate memories during sleep and offers a potential new avenue for addressing conditions like post-traumatic stress disorder, anxiety, and depression. While the technology is still in development and has risks to consider, the potential for sleep engineering to provide effective and non-invasive treatment options is promising. Stimulating the Sleeping Brain Could Help Heal Memory Loss or Mental Health Problems | Scientific American

Mind Matters: p-Factor of Mental Illness

Mental illnesses often display a perplexing overlap, challenging the traditional diagnostic boundaries set by the DSM. This phenomenon is exemplified by the case of a Ph.D. student with schizophrenia whose family members suffer from a range of psychiatric conditions. Researchers attribute this overlap to a concept known as the "p factor," a general psychopathology factor that suggests a shared genetic predisposition to various mental disorders. Evidence indicates that about 40% of the risk for mental illness can be explained by this factor. This has led to a call for reevaluating diagnostic classifications and treatment approaches, advocating for a focus on commonalities rather than distinct categories. The pursuit of understanding the p factor involves exploring genetic correlations, brain structures, and psychological traits to develop more effective, generalized treatments for psychiatric illnesses. However, the concept remains contentious, with critics questioning the statistical models used to justify the p factor's existence and suggesting that mental illnesses may fall into broader categories rather than sharing a common set of features. Why Do So Many Mental Illnesses Overlap? | Scientific American

The Psychedelic Potential of Ibogaine

Ibogaine, a natural psychoactive compound derived from the iboga tree's bark, is gaining attention for its potential in treating addiction, PTSD, and brain injuries. Despite being illegal in the United States, it has shown promise in small studies for reducing opioid dependency and cravings. The drug's mechanism is believed to involve neuroplasticity, allowing patients to reevaluate their behavior and trauma. However, its legality is a barrier to access, and it carries risks of fatal cardiac arrhythmias. Ibogaine's treatment experience is intense, often involving confronting past traumas. While some studies, particularly in Brazil, support its anti-addictive properties, the lack of large-scale clinical trials and its cardiac risks make FDA approval unlikely soon. What to Know About Ibogaine, a Psychedelic - The New York Times (gift article).

Feelings Under Surveillance

The article Emotion-tracking AI on the job discusses the growing use of emotion-tracking artificial intelligence (AI) in the workplace, which analyzes biological signals and computer usage to infer employees' emotions. Despite claims of benefits like improved well-being and productivity, workers express concerns about privacy, bias, and the potential for inaccurate or unfair employment decisions. The technology, often seen as flawless by employers, has been criticized for its scientific validity and reliance on contested theories of emotion. The study highlights the additional emotional labor imposed on workers, who must mask their true feelings to present favorably to the AI, exacerbating existing workplace challenges. Critics suggest that its use should be reevaluated until the technology's implications are fully understood.

The Divergent Paths of Discordant Twins

A comprehensive study involving 25,252 Swedish adult twins, published in JAMA Psychiatry, has provided substantial evidence on how childhood trauma influences adult mental health. The research focused on "discordant twins," where only one twin experienced abuse or neglect. The findings revealed that those who faced childhood trauma were significantly more likely to be diagnosed with psychiatric illnesses such as depressive disorders, anxiety disorders, substance abuse disorders, or stress disorders. The impact of trauma was evident even after controlling for genetic and environmental factors, highlighting the profound effect of childhood adversities on adult mental well-being. This study underscores the urgent need to address child abuse and neglect to prevent long-term mental health consequences. One Twin Was Hurt; the Other Was Not. Their Adult Mental Health Diverged. - The New York Times (gift article).

072 - Spice Odyssey, Pillow Talk, and Filing for Ecstasy - HealthHippieMD Week In Review

AI in Academia

In the University of Mississippi's Department of Writing and Rhetoric, Marc Watkins, a self-proclaimed AI guru, is navigating the transformative impact of large language models like ChatGPT on student learning. These AI tools significantly alter how students engage with writing and reading, sometimes even taking over these tasks for them. Watkins' approach to faculty meetings often starts with the quip, "Remember what I told you last week? Forget it," highlighting the rapidly evolving nature of AI in educational settings and its profound implications for teaching methodologies. Opinion | How AI is transforming education at the University of Mississippi - The Washington Post (gift article).

Spice Odyssey

The article How cinnamon, nutmeg and ginger became the scents of winter holidays, far from their tropical originsexplores how these spices, originally from tropical regions, have become synonymous with winter holiday festivities in the Northern Hemisphere. These spices, known for their 'warm' flavors, have a rich global trade and exploration history. Ginger, used in sweet and savory dishes, requires 8-10 months to mature and can be harvested year-round. Nutmeg, derived from the Myristica fragrans tree in Indonesia, takes years to reach peak production, offering nutmeg and mace from its seeds. Cinnamon, harvested from tree bark, is best collected after heavy rains or soaking in water. These spices add distinctive flavors to holiday dishes and offer health benefits. Cinnamon, for instance, can reduce blood glucose levels, ginger aids digestion, and nutmeg has anti-diabetic properties. Their integration into winter holiday traditions is a testament to the enduring influence of the spice trade and the global exchange of culinary practices.

The Elusive World of Hidden Carcinogens

The article The Fight Against Cancer Turns to a Special Class of Carcinogens in The New Yorker delves into the complexities of identifying and understanding carcinogens that don't directly cause mutations in cells but play a crucial role in cancer development. It highlights the limitations of traditional methods like the Ames test in detecting these carcinogens. The piece explores the work of scientists like Bruce Ames, Allan Balmain, and Charles Swanton, who have contributed to our understanding of carcinogenesis. The article discusses how certain substances, while not directly mutagenic, can act as cancer promoters by altering the environment around cells or interacting with pre-existing mutations. This exploration into the 'dark matter' of carcinogens challenges the conventional approach to cancer research, suggesting a need to broaden our perspective and methodologies to include these elusive cancer-promoting agents.

Aging Gracefully

A BLUEPRINT FOR ANTI-AGING (Apple News+) provides valuable insights into the aging process and offers practical tips for maintaining a youthful appearance and prolonging lifespan. The document covers a range of lifestyle factors that can impact aging, from the importance of exercise and a healthy diet to the benefits of good oral hygiene and quality sleep. Additionally, the PDF explores the biological hallmarks of aging and offers advice for measuring biological age at home. With helpful tips on everything from wearing sunscreen to strength training, this document is a must-read for anyone looking to age gracefully.

Filing For Ecstasy

MAPS Public Benefit Corp. has taken a groundbreaking step by filing an application with the U.S. Food and Drug Administration to approve MDMA, commonly known as Ecstasy, combined with therapy for treating post-traumatic stress disorder (PTSD). This marks a significant milestone in the journey of psychedelic drugs from restricted substances to potential mainstream medical treatments. The application follows decades of research showing the potential of psychedelics like psilocybin and ketamine in treating mental health disorders. If approved, MDMA-assisted therapy would be the first of its kind, potentially setting a precedent for future psychedelic treatments. The treatment involves psychotherapy sessions supplemented with MDMA, aiming to provide a new avenue for those suffering from PTSD. This development reflects a growing recognition of psychedelic treatments, with the FDA increasingly acknowledging their potential therapeutic value. MAPS seeks approval of Ecstasy- or MDMA-assisted therapy - The Washington Post.

MedLM in Medicine

Google's new suite of health-care-specific AI models, MedLM, is set to leave its mark on healthcare. MedLM includes large and medium-sized models built on Med-PaLM 2, a language model trained on medical data. This innovation aims to assist clinicians and researchers in complex studies and summarizing doctor-patient interactions. Companies like HCA Healthcare have been testing Google's technology, using it for tasks like automatic documentation of patient interactions and developing tools for nurse handoffs. While the technology shows promise in improving workflows and reducing clerical work, challenges such as accuracy and implementation remain. Google plans to further enhance MedLM with health-care-specific versions of Gemini, its newest AI model, indicating a significant step towards AI integration in healthcare. How doctors are using Google's new AI models for health care.

Many Holiday Returns

The Atlantic has a curated list of articles on shopping returns. "When my colleague Amanda Mull ventured into the belly of the holiday-returns beast, she learned that somewhere amid a complex system of transporters, warehousers, and resellers, a guy named Michael has to sniff the sweatpants." The Fate of Your Holiday-Season Returns - The Atlantic.

Pillow Talk

Do Sleeping Pills Work? A Guide to Insomnia Drugs and Their Risks - The New York Times (gift article) offers a guide to insomnia medications, their potential risks, and when they should be used. With a variety of prescription and over-the-counter options available, including suvorexant and antihistamines, this article explores the golden age of insomnia drugs. Experts advise limited use, cautioning against habit-forming tendencies and emphasizing the importance of consulting a healthcare provider. Whether it's a short-term relief or a last resort, this informative piece provides valuable insights into managing sleep issues while shedding light on the complexities of sleep medication dependency and safe withdrawal methods.

068 - Mitophagy, Crapsules, and VR for Pain - HealthHippieMD Week In Review

Artificial Inaccuracy

The article ChatGPT Quickly Authored 100 Blogs Full of Healthcare Disinformation, discusses a study where generative AI, particularly ChatGPT, was used to produce a large volume of healthcare disinformation rapidly. ChatGPT created 102 blog articles with over 17,000 words of disinformation on vaccines and vaping in just 65 minutes. The study, conducted by Australian researchers and reported in "JAMA Internal Medicine," also involved using AI tools like DALL-E 2 and HeyGen to create realistic images and a deep-fake video to accompany the blog posts. Notably, other AI programs like Google Bard and Microsoft Bing Chat did not facilitate such disinformation production. The study underscores the potential misuse of AI in spreading persuasive, customized disinformation efficiently, posing significant risks if exploited by malicious actors.

Dose of Reality: Unraveling the Complex Prescription Drug Financing in the U.S.

The article Following the Money: Untangling U.S. Prescription Drug Financingprovides a critical analysis of America's high prescription drug costs. It reveals that the U.S. leads in per capita drug spending, averaging $1,432 per person in 2021. This in-depth investigation into the U.S. healthcare system uncovers the multifaceted reasons behind this substantial financial burden. The article aims to shed light on the convoluted nature of prescription drug financing in the U.S., contrasting it with its international counterparts.

The Honest Truth About Fibs

Recent research reveals intriguing insights into lying habits. Surprisingly, 59.9% of people reported not lying in a day, with half of all lies coming from just 5.3% of participants. The study found that the frequency of lying is relatively unaffected by the communication medium, whether face-to-face, text, or email. Additionally, while minor lies are commonly told to strangers, significant lies are often reserved for close partners or family members. These findings, although reliant on self-reported data (leading to the possibility of significant inaccuracy), suggest that most people are generally truthful in their daily interactions. A New Study Estimated The Number of Times An Average Person Lies Per Day.

U.S. Dietary Guidelines Eyeing Ultra-processed Food

The upcoming revision of the U.S. dietary guidelines may mark a significant shift in nutritional focus by potentially warning against consuming ultra-processed foods. This change, influenced by mounting evidence linking these foods to a range of chronic diseases like obesity, heart disease, and diabetes, could profoundly impact national food programs, including the National School Lunch Program, and the overall dietary habits of Americans. Critics have long criticized current guidelines for overlooking the effects of food processing and additives. The food industry, fearing potential impacts, has already begun lobbying against such recommendations. The next guidelines edition is due in 2025, with an advisory committee report expected next year, potentially leading to a major overhaul in how Americans perceive and consume food. Nutrition guidelines may soon warn against ultra-processed foods - The Washington Post. (gift article)

FTC Takes a Bite Out of Misleading Influencer Marketing of Food

The FTC has warned significant food and beverage industry groups and numerous dietitian influencers, spotlighting a crackdown on undisclosed paid advertising on social media. Targeting American Beverage and the Canadian Sugar Institute, alongside influencers with over 6 million followers, the FTC points out non-transparent endorsements of artificial sweeteners and sugary foods. This move, spurred by The Washington Post and The Examination investigations, aims to enforce clear disclosure standards across influencer marketing. It represents a significant shift in the FTC's approach, with potential fines exceeding $50,000 per violation, signaling a tougher stance against deceptive social media advertising practices. FTC cracks down on food industry for paid dietitian influencer posts - The Washington Post. (gift article)

Mitophagy and Aging

Scientists at the Buck Institute have made a breakthrough in understanding aging by focusing on mitochondria, the cell's powerhouses. Their study, published in Nature Aging, highlights a natural compound, Mitophagy-Inducing Coumarin (MIC), that extends the lifespan of Caenorhabditis elegans, a model organism in aging research. MIC boosts the cell's waste management system, mainly targeting old and damaged mitochondria for disposal, a process known as mitophagy, which naturally declines with age. This discovery could lead to new therapies for age-related diseases by enhancing autophagy, the body's innate rejuvenation process. However, while MIC has shown promising results in worms, further research is needed to determine its effects on human aging. New Anti-aging Molecule May Work By Keeping the Cell's "Powerhouse" Healthy.

Crapsules: The Future of Medicine

In the field of microbiome medicine, a revolutionary shift is underway. Medical teams are transforming donated fecal matter into pills to combat infections like Clostridium difficile. These "crapsules" represent a broader scientific awakening to the importance of the gut's microbiome. Fecal transplants have proven to be efficacious in treating Clostridium dificile (a common life-threatening gut infection, often seen after broad-spectrum antibiotic treatment). Researchers are now exploring advanced strategies, including metabolite manipulation and genetically engineered bacteria, to treat a range of conditions more effectively. The FDA's recent approval of Seres Therapeutic's SER-109, an oral microbiome therapeutic, signifies a major leap in this field. With companies like Seres Therapeutics and Vedanta Biosciences at the forefront, the future of microbiome medicine appears promising, moving beyond the crude efficacy of FMT towards more sophisticated treatments. Microbiome treatments are taking off. (disclosure: I own shares of Seres Therapeutics)

Virtual Reality: A Real Game-Changer in Pain Management

The pain is real. The painkillers are virtual reality. | MIT Technology Review discusses RelieVRx, a virtual reality (VR) system designed to manage pain. Unlike traditional painkillers, RelieVRx aims to teach patients pain relief strategies such as mindfulness, cognitive-behavioral therapy, and relaxation rather than just providing a distraction. The approach is based on "unlearning" physiological pain responses and reinforcing alternative coping mechanisms. This innovative method offers a new frontier in pain management, leveraging the immersive capabilities of VR technology.

052 - Genetic Judo, Young Blood, and Gray Hair - HealthHippieMD Week In Review

Age is Just a Number

As seniors face complex health decisions, age alone may not be the best guide. Medical associations and health groups are shifting to consider life expectancy when recommending screenings and treatments. With the average life expectancy of a 75-year-old being 12 years, online tools like the "Know Your Chances" calculator can estimate mortality and disability risks, providing valuable context beyond age. By incorporating factors like smoking history and health status, patients can make more informed decisions about their healthcare, ultimately improving outcomes and avoiding unnecessary treatments. A Number That Should Guide Your Health Choices (It's Not Your Age) - The New York Times (gift article)

Immune System Influences Behavior

A recent study found the immune system (at least in mice) plays a role in altering our behaviors, especially in response to allergic triggers. "We find immune recognition controls behavior, specifically defensive behaviors against toxins that are communicated first through antibodies and then to our brains." Our Immune System May Help Guide Behavior

Humata.AI: ChatGPT to Query Academic Manuscripts

If you rely on academic publications for your work, prepare to have your mind blown. With Humata.AI,, after uploading a pdf of a manuscript, you can ask questions about the content or ask questions about a folder full of articles in aggregate. It worked incredibly well in the manuscripts I tried. My only complaint about this nascent tool was the limited ways to interact with the content, but I'm sure features will expand as the tool matures. Humata.ai worked much better in my experimentation than another tool I tried, Liquidtext. I suspect the field will get increasingly crowded with science-aware chatbots. Humata.AI is free for the first 60 pages of content, $15/month for more.

Using ChatGPT to Improve Your Writing

Large Language Models, like ChatGPT, are helpful in various ways for writing. Here are some ideas: 5 Ways ChatGPT Can Improve, Not Replace, Your Writing +And here is an article about using ChatGPT in medical diagnosis: A Mystery in the E.R.? Ask Dr. Chatbot for a Diagnosis.

Yo-Yo Diet Industry's Latest Spin

The weight loss industry is witnessing a new wave of reinvention as Americans continue their yo-yo relationship with dieting. Diet apps like Noom and WW (formally WeightWatchers) are now adopting a psychological approach to weight loss, emphasizing self-acceptance and joyful movement. Recently, Noom and WeightWatchers have integrated GLP-1 obesity drugs like Ozempic into their services, acknowledging that medications can be crucial in achieving good health for many. This shift reflects the desire to lose weight, though the approach has evolved from moralizing to a more attainable, value-neutral goal. The Diet Industry Is Pivoting to Ozempic

Unraveling the Mystery Behind Graying Hair

Gray hair is a visible example of how genetics and aging interact. Hair gets its color from melanin, a natural pigment produced by melanocytes. As we age, stem cell melanocytes can become trapped, leading to gray hair. Stress may also play a role in graying. While there's no reliable way to prevent or reverse gray hair, recent research suggests some intriguing possibilities. Why Does Our Hair Turn Gray? The Science of Aging Hair, Explained

Health System Monopolies

The NY Times published an opinion piece on healthcare monopolies: Opinion | The Ridiculous Medical Bill Brought to You by the Latest Hospital Merger - The New York Times (gift article). Hospital mergers and consolidations have created monopolies in the healthcare system, leading to decreased patient choice, rising prices, and limited innovation. The Biden administration has attempted to address the issue with antitrust activity, but hospital mergers have proven harder to curb compared to other industries. The Federal Trade Commission faces challenges blocking hospital mergers due to lengthy analysis and limited resources. Vertical mergers, where extensive hospital systems acquire smaller ones or doctors' practices, further exacerbate price increases. States are now considering price regulation as a possible solution to rein in the power of giant health systems.

Learning on Vacation

In this article, Arthur C. Brooks explores a vacation model often overlooked—turning leisure into learning. Research suggests that pursuing intrinsic interests and learning something new enhances well-being, even if it involves some sacrifice. By focusing on activities that captivate our curiosity, like taking a class or engaging in a guided retreat, vacations can be transformed into rewarding and content-filled experiences. So, instead of conventional models, consider turning your time off into an opportunity for personal growth and happiness. How to Have Your Most Fulfilling Vacation Ever

Young Blood Slows Aging (in Mice)

In a groundbreaking study, scientists extended the lifespans of older mice by connecting their blood vessels to younger mice, resulting in a 6 to 9 percent longer life for elderly rodents. Though not an anti-aging treatment for humans, the research suggests that compounds present in the blood of young mice may promote longevity. The experiment involved parabiosis, joining the animals together for an extended period, and upon separation, the aging process of the older mice appeared to have reversed, making them biologically "younger." Blood of Young Mice Extends Life in the Old - The New York Times (gift article)

Genetic Judo

"It's very cool. It turns something the cancer cell needs to stay alive into something that kills it, like changing your vitamin into a poison." Scientists at Stanford have developed a novel molecule that could potentially lead to groundbreaking cancer drugs. The molecule links cancer-driving proteins to cell-death genes, effectively turning the molecules promoting deadly growth into self-destruction triggers. In lab experiments, this dumbbell-shaped molecule was successful in activating cell-death genes in a blood cancer, diffuse large B-cell lymphoma. Flipping a Switch and Making Cancers Self-Destruct - The New York Times (gift article)

046 - Holobionts, Embracing Death, and the Moral Crisis of Physicians - HealthHippieMD Week In Review

Embrace Death for a Happier Life

Contemplating mortality may seem grim, but it is critical to a fulfilling existence. Drawing inspiration from Randy Pausch's remarkable Last Lecture, experts argue that acknowledging our finite existence enhances happiness. Avoiding thoughts of death leads to regret and postponing meaningful experiences. By embracing the reality of death, we make wiser choices, cherish relationships, and appreciate life's fleeting moments. Deliberately confronting mortality cultivates positive thinking and clarity, enabling us to live each day to the fullest. Think About Your Death and Live Better - The Atlantic

Taurine: a Longer Life or Just Bull?

A recent study in the journal Science suggests that taurine, a common amino acid, may be essential to anti-aging and longevity. Researchers discovered that taurine levels decline as organisms age, leading to tissue damage. However, supplementing taurine in the diets of worms, mice, and monkeys extended their lifespans and reversed age-related damage in their muscles, bones, and brains. More research is needed.Can Taurine, Found in Energy Drinks, Slow Down Aging? - The New York Times

Bots with Bedside Manner

In the article, Doctors Are Using ChatGPT to Improve How They Talk to Patients - The New York Times (gift article) the unexpected use of artificial intelligence (AI) chatbot ChatGPT by doctors is explored. While AI models like ChatGPT have the potential to assist with mundane tasks and improve efficiency, doctors have discovered their value in enhancing compassionate communication with patients. (Thanks, NextDraft)

We Are Multitudes: The Rise of Holobionts in Biology

In a paradigm shift for biology, the concept of "holobionts" is gaining recognition, emphasizing the interconnectedness of animals, plants, and their microbiota. The Leverhulme Centre for the Holobiont studies insects, amphibians, and plants to understand the symbiotic relationships within these organisms. Holobionts challenge the notion of a monogenic individual, highlighting the importance of the microbiome in evolution, health, and even agriculture. By unraveling the intricacies of holobionts, scientists are uncovering new insights into the world of multi-organismal biology. The idea of "holobionts" represents a paradigm shift in biology.

A New Beatles Song, Thanks to AI

The Beatles are going to release a new song later this year. Paul McCartney said he used technology to 'extricate' John Lennon's voice from an old demo and complete a decades-old piece. I can't wait. AI used to create new and final Beatles song, says Paul McCartney | The Guardian

The Military Method for Falling Asleep Quickly

A brief article with a method used by the U.S. Army to promote sleep in the worst conditions: The 5-step "military method" for falling asleep in minutes.

Sound Check: Noise and Health

"Chronic noise exposure is not just a nuisance, scientists say. It's a health risk." The article Are You Exposed to Too Much Noise? Here's How to Check. - The New York Times (gift article) explores the detrimental effects of chronic noise exposure on both hearing and cardiovascular health. As noise levels continue to rise, the risks of cardiovascular disease increase. The article provides resources for measuring noise exposure, such as an online noise map and the NIOSH Sound Level Meter app. It also offers tips for protecting oneself. By understanding and managing noise exposure, individuals can safeguard their well-being.

The Moral Crisis of American Doctors

The article, The Moral Crisis of America's Doctors - The New York Times (gift article), about the corporatization of medicine, spoke deeply to me. A must read.....

Distract to Connect

New research suggests that shared distraction can be a more effective way to foster genuine connections in a world obsessed with constant attention. Engaging in activities that divert focus from ourselves, such as physical exercise or exploring the environment, enhances social connectedness and creative thinking. By embracing distractions and incorporating them into our interactions, whether online or in person, we can strengthen relationships and enjoy more enriching conversations. Embrace Distraction. Your Friends Will Thank You. - The Atlantic

NCCIH Free Online Education

The National Center for Complementary and Integrative Medicine (NCCIH) has an expanding library of free educational seminars on the science behind complementary and integrative approaches: NCCIH Online Continuing Education Series.

Going the Extra Mile

In the article, Overtraining syndrome: How much exercise is too much,, Slate explores the dark side of endurance running and the potential for it to become a form of self-harm. While exercise is widely recognized for its physical and mental health benefits, pushing the boundaries can have detrimental effects. The article delves into personal stories of individuals addicted to pain and extreme physical challenges, highlighting the need to recognize one's limits and prioritize overall well-being. The author emphasizes the importance of finding a balance between perseverance and excess in the pursuit of athletic achievements.

How To Exercise When It's Humid

Humidity is ratcheting up here in North Carolina. The New York Times had a piece on exercising in humid weather: Tips for Exercising in Humidity.

044 - Biophilic Design, Hallucinations, and Erasing Memories - HealthHippieMD Week In Review

Strobe Lights Induce Visual Hallucinations

Wired U.K. featured a story about Dreamachine, where people experience hallucinatory effects through stroboscopic lights and music. The project aims to explore the impact of stroboscopic lights on the brain and investigate the neural basis of visual experience. Participants, even with closed eyes, reported vivid and kaleidoscopic visual experiences. The Dreamachine's potential applications extend to mental health therapy due to the reported common emotion of peace experienced by participants. This Machine Makes You Hallucinate | WIRED

Erasing Psychedelic Trips for the Good of Science

To address criticisms of psychedelic research, scientists at the University of Wisconsin–Madison Transdisciplinary Center for Research in Psychoactive Substances conducted a pilot study involving eight individuals, exploring the possibility of combining psychedelics with memory erasure. The study addresses the challenge of studying psychedelics in traditional randomized clinical trials due to the subjective nature of the experiences and the role of expectations. By exploring innovative study designs, scientists strive to better understand psychedelics' effects and potential therapeutic applications. Scientists Gave People Psychedelics—and Then Erased Their Memory

The Whimsy of Honoring Body Donors

Medical students and faculty members across the United States are organizing gratitude ceremonies to honor body donors who have contributed to medical research and education. These ceremonies involve music performances, speeches, and artistic expressions, allowing students to express appreciation for the donors who have served as their "first patients." The ceremonies aim to re-humanize the donors, recognizing their selfless acts and the sacrifice made by their families. The events provide closure and foster a sense of gratitude while imparting essential lessons in ethics and professionalism. Honoring the Body Donors Who Are a Medical Student's 'First Patient' (gift article)

Conversational Receptiveness: Mastering the Art of Disagreement

To have better disagreements, change your words – here are four ways to make your counterpart feel heard and keep the conversation going discusses the importance of changing our words and behaviors during disagreements to foster productive conversations. Instead of solely focusing on persuading others, the research suggests adopting a communication style called "conversational receptiveness." This style involves four key elements: hedging claims, emphasizing agreement, acknowledging the opposing perspective, and reframing to the positive. By employing these techniques, conversations become less confrontational and more constructive, allowing both parties to feel heard and maintaining relationships.

Rousing Revelations: Some Mental Illness May Have Autoimmune Origin

WaPo published a story about a groundbreaking case involving April Burrell, a catatonic woman diagnosed with schizophrenia. Researchers discovered that lupus, an autoimmune disease, attacked April's brain, leading to severe symptoms. After targeted treatments, including immunotherapy, April regained consciousness after being trapped in her mind for over two decades. This discovery has the potential to revolutionize the care for psychiatric patients worldwide and reshape the way mental illnesses are diagnosed and treated, bringing hope to "forgotten souls" who were deemed untreatable. How autoimmune disease can attack the brain, cause psychiatric symptoms - The Washington Post (gift article)

Function Over Flaws

A revolutionary new health metric called human functioning could alter the treatment of chronic illnesses. Traditionally, health has been measured based on morbidity and mortality rates, focusing solely on disease and death. However, the proposed metric considers a person's illness and available resources to gauge their condition's impact on daily life activities. This approach aims to shift the healthcare system toward a patient-centered approach, promoting well-being and enabling individuals to live their best lives. This New Metric For Health Could Revolutionize How We Treat Chronic Illnesses

Byte-Size Nutrition

Artificial intelligence (A.I.) nutritionist apps are revolutionizing healthy eating by offering personalized diet solutions. These apps use A.I. algorithms to analyze data on an individual's blood sugar, microbiome, and other metabolic measurements. By understanding how different foods affect each person's body, these apps can suggest healthier meal options. While personalized nutrition is still evolving, A.I. programs hold the potential for addressing obesity, heart disease, and other health concerns. Here Come the Artificial Intelligence Nutritionists

+A reminder, buyer-beware when it comes to A.I. advice (although the chatbot mentioned in this article is different than ChatGPT): An Eating Disorder Chatbot Is Suspended for Giving Harmful Advice^4a50c0

Music and Health: The Evidence

The NCCIH has a web page focused on Music and Health: What You Need To Know.

Nature at Home: A Prescription for Well-being

WaPo had an article about the science-backed concept of "biophilic design" that promotes connecting with nature indoors. 7 ways to bring nature into your home, according to science. (gift article)

Green Brain: Brain Aging Delayed with Mediterranean Diet

A recent study reveals that a Mediterranean diet can slow brain aging. The research indicates that a mere 1% reduction in body weight resulted in brains appearing almost nine months younger. Greener Diet, Younger Brain: Mediterranean Diet Slows Brain Aging.

Ultra-processed Food and Sleep Quality

"No study had previously investigated what happens if we consume an unhealthy diet and then compare it to the quality of sleep after that person follows a healthy diet." In this small preliminary study, an unhealthy diet impacted each individual's sleep quality. Junk Food vs. Sleep: New Study Reveals Impact of Diet on Sleep Quality.

041 - Doctor Dog, AI Mind-Reading, and Smelling Virtual Roses - HealthHippieMD Week In Review

Long Telomeres

"Short telomeres were thought to be bad — people with premature aging syndromes had short telomeres — so, by analogy, long telomeres were thought to be good..." A paper published last week, Familial Clonal Hematopoiesis in a Long Telomere Syndrome | NEJM, challenged current assumptions about telomere length. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds - The New York Times

Rapamycin

"Rapamycin is a paradoxical drug. It improves anti-cancer immunity, but it may also cause cancer. It protects against bacterial infection, halts viral replication, and suppresses the immune system. It reverses symptoms of Alzheimer's disease but also increases plaque deposits in the brain. It improves metabolic function, but it also causes type 2 diabetes. This list of contradictions goes on and on; however, there is one thing about Rapamycin that scientists tend to agree on: it is potentially the most powerful anti-aging drug ever discovered." I learned quite a bit from the article: Rapamycin: Unlucky history of the most powerful anti-aging drug.

ChatGPT's Empathetic Bedside Manner

In a recent study, healthcare professionals preferred the responses from A.I. over those from flesh-and-blood doctors. Could generative A.I. have a place in the future of healthcare-patient interaction? ChatGPT Has a Better 'Bedside Manner' Than Doctors.

+Quartz has some suggestions on how to get more out of your ChatGPT queries: How to use ChatGPT at work.

Futile Care

The Atlantic had an interesting opinion piece on the importance of end-of-life planning: An ICU nurse reflects on futile care. _"But what I think and feel doesn't matter. What matters is what the patient would think and whether the people who make choices about their care both know what the patient would think and understand the likelihood that their choices will have this result. This is often not the case."

Inside the Upcoming $1.5 Trillion Farm Bill

The Conversation published a peek behind the curtain as the government ramps its efforts to bring forth the next farm bill. These four challenges will shape the next farm bill – and how the U.S. eats.

The Association Between Season Allergies and Mood Disorders

"Not only are the physical symptoms draining, but a growing body of research also shows an association between allergic rhinitis — commonly known as hay fever — and mood disorders like anxiety and depression." How Seasonal Allergies Can Affect Mental Health.

Childhood Obesity

Obesity in U.S. children was already high and was exacerbated by the pandemic.Obesity in children is rising dramatically, and it comes with major – and sometimes lifelong – health consequences talks about the trend and its implications.

Mindfulness and Meditation

The benefits of mindfulness and meditation practice are numerous. The article Mindfulness, meditation, and self-compassion discusses benefits and gives practical steps to begin your practice.

Noggin Reading

Scientists have developed a mind-reading technology powered by A.I. that can decode a person's thoughts into speech. The researchers used functional magnetic resonance imaging (fMRI) and a large language model to analyze brain recordings and translate them into sentences. Although the technology's potential to help those who have lost their ability to speak, like stroke victims, is promising, it raises ethical privacy concerns. Mind-reading technology, powered by A.I., sparks ethical concerns.

Oh, Look At All the Lonely People

A recent study suggests that the brains of lonely people respond to visual stimuli in unique ways, unlike non-lonely people, implying that lonely people may view the world differently. The findings also suggest that being surrounded predominantly by people who view the world differently from oneself may be a risk factor for loneliness. The brains of lonely people process the world differently

Ode to the Human Genome Project

The Economist had an excellent article on the Human Genome Project, How the Human Genome Project revolutionized biology, although I was disappointed not to see the microbiome mentioned. As Julien Davies pointed out, the HGP is incomplete until we understand the role of microbial DNA: In a Map for Human Life, Count the Microbes, Too | Science.

Tweaking Vegetable Genes for Taste

Scientific American published an article on how CRISPR gene editing technology is being used to improve the taste of food: Tweaking Vegetables' Genes Could Make Them Tastier--And You'll Get to Try Them Soon - Scientific American (Thanks Dave Pell - NextDraft)

Doctor Dog

The article How My Dog Knows When I'm Sick is about how dogs can sense when their owners are sick and the signals they use to detect it. According to researchers, dogs can smell changes in their owners, including a virus or bacteria infection. They can also pick up on emotional changes, such as depression or lethargy, through the owner's voice changes. While it's unclear what dogs make of these changes, they may be more curious or suspicious than concerned. Nonetheless, dogs' empathy has significant benefits for human health.

Smell the (Virtual) Roses

Olfaction is tightly coupled with the parts of the brain responsible for emotions and memory. The evocative nature of the sense of smell is why companies are interested in deploying smell in the Metaverse: How to bring scents to the Metaverse and Smelling in V.R. environment possible with new gaming technology.

039 - Centenarian Excrement, Creativity, and Cannabinoids - HealthHippieMD Week In Review

How to Make Peace with Your Feelings

How Leaning Into Negative Emotions Can Help Your Mental Health (gift article) is about accepting negative emotions for what they are: part of the human experience. What you do with the experience strongly influences your health and well-being.

Generative AI in Medicine

Wired had a story about ways generative AI will impact medicine, along with several caveats: ChatGPT Can Help Doctors—and Hurt Patients.

The Two Personality Traits that Predict Well-being

If you lack either (I'm strongly introverted, not extroverted), hope is not lost. Study Finds 2 Personality Traits Predict Well-being — But Don't Worry if You Don't Have Them.

The World's Rarest Eye Colors

Do you have one of the six rarest types of eye color? Read What Is the Rarest Eye Color?.

Is Alcohol in Moderation Good for You?

The Great Alcohol Health Flip-Flop Isn't That Hard to Understand—if You Know Who Was Behind It is an interesting article on how the supposed health benefits of a small amount of alcohol have been turned on its head, again.

What You See Is Not Always What You Get

The NY Times had an article about a recent publication in JAMA focused on melatonin gummies: "A team of researchers analyzed 25 melatonin gummy products from different brands and found that 22 contained different amounts of melatonin than what was listed on their labels; one contained only 74 percent of the advertised amount of melatonin, while another had 347 percent of the labeled amount. Yet another product contained no detectable melatonin at all." 22 Out of 25 Melatonin Products Were Mislabeled, Study Finds. (gift article) See also: ConsumerLab: Independent Testing of Supplements and Botanicals.

Hope

The Atlantic had an interesting article, Why Economists Should Study Hope, that discusses why hope is so important and how to cultivate more.

The Quest for Longevity

The Quest for Longevity Is Already Over is an interesting read. One of the points I strongly agree with in the article is that extending healthspan (the length of time one is healthy) is far more important than extending longevity (the length of time one lives).

Oura Partners with Best Buy

I love my Oura smart ring. I've worn mine for years. The hardest part of the purchase process was the sizing. Sizing will be less of an issue as you can soon walk into Best Buy and find a fitting station. The article Oura Is Proof That Smart Rings Are Here to Stay discusses the Oura Ring and some of the upcoming competitors.

Cannabis, Cannabinoids, and Delta-8 THC / Delta-10 THC

Cannabis-derived products like delta-8 THC and delta-10 THC have flooded the US market – two immunologists explain the medicinal benefits and potential risks is a quick overview of some of medicinal and side effects of cannabinoids. The article discusses hemp, cannabis, and a few of the cannabinoids.

Creativity / Rick Rubin

I enjoy writing words and music. I'm not good at either, but the process brings me joy. Rick Rubin's new book is about the creative process: The Creative Act: A Way of Being: Rubin, Rick. I've been a big fan of Rubin's Broken Record Podcast. I also enjoyed watching Rick Rubin: The 60 Minutes Interview - CBS News and hearing him interviewed on Rick Rubin on How to Make Something Great. I'm adding the book to my "must-read" list.

Brainstorming with ChatGPT

Wired had an article on how to brainstorm better with the generative AI platform: 6 Tips for Using ChatGPT to Brainstorm Better

What Can We Learn About Aging from Centenarian Excrement?

The longest-living people have a more diverse microbiome than their less healthy peers. A study published this month, Longevity of centenarians is reflected by the gut microbiome with youth-associated signatures looked at the gut microbiomes of centenarians — individuals who've reached or surpassed a century in age — and compared them against old, middle-aged, and young adults. Their results showed, "regardless of health status, the centenarians had a unique enterotype that is a combination of the two found in young adults aged 20 to 44 — Bacteroides — and older adults — Escherichia and/or Shigella." Read the study synopsis here: Centenarians Have Super Healthy Gut Microbiomes — Can This Help Us Live Longer?

Pill Popping Polypharmacy

"Getting people off drugs is unfamiliar terrain for modern health systems, mostly set up to put patients on them. But that is beginning to change. Doctors, pharmacists, and nurses are setting up "deprescribing networks" to try to spread the word." The Economist published an article on the overprescription of medication: Too many people take too many pills.

FDA-Approved Video Games

Much of my research at Duke focused on using video game technology in healthcare and healthcare education. It was fantastic to read this synopsis of Akili [^1] and EndeavorRX, an FDA-approved video game for treating ADHD. I can think of many more uses of the platform. The story behind an FDA-Approved Video Game Treatment for ADHD


[^1]: I am an Akili Interactive shareholder.

031 - Science / Pseudoscience of Aging, Cannabinoids and Cancer, and The World's Hottest Pepper - HealthHippieMD Week In Review

For Love of the Bean

This author loves their coffee (in reality, caffeine). "A low dose of caffeine can lead to a significant increase in … happiness and calmness and decreases in tenseness." Coffee really does make you happier

What's Your Subjective Age?

There is frequently a difference between our chronological age and our subjective age. This author examines the phenomenon: I'm 53 years old. I'm 36 in my head. - The Atlantic

The Science and Pseudoscience of Aging

Scientists are working diligently to unravel the aging process. I mentioned some of this work in 027 - Wise-Selfishness, Horvath's Clock and GrimAge - HealthHippieMD Week In Review. Here is an excellent video overview of the quest to extend our lives, including an interview with Steve Horvath: The Future with Hannah Fry And another interesting, more scientific overview of the field: Turning back time with epigenetic clocks - Nature

+More on the brave new world of chronological-age testing start-ups: How Old Are You, Really? New Tests Want to Tell You

+More on longevity research: Can We Change How Fast Humans Age? A New Study Is Getting Closer to the Answer

Periodontal Disease and Rheumatoid Arthritis

Scientists at Stanford have been working on why there is an association between poor oral health and more severe rheumatoid arthritis: Oral bacteria trigger rheumatoid arthritis flare-ups

The Last of Us

I'm enjoying the HBO series, The Last of Us. The premise that a fungus infects humans and does everything in its power to spread is borrowed from the animal world. The article, Can a Fungus Really Take Over Our Brains?, is an overview of known pathogens that alter HUMAN behavior. If you want to binge another great sci-fi/horror show, try Fortitude, supposedly one of the most scientifically accurate sci-fi shows ever made.

How to Deal with Dark Personalities at Work

Dark personalities: narcissists, psychopaths, and Machiavellians are common in society. Here is some advice on how to navigate your interactions with them at work: Here's what to do when you encounter people with 'dark personality traits' at work

A Reading List on the Neuroscience of Reading

According to the intro, humans were not designed to read. Here is a series of long-form articles on one of life's greatest pleasures: A Reading List About the Neuroscience of Reading

Digital Declutter

"Just as clutter in your home can cause stress, erode productivity, and hurt your sense of well-being, digital clutter, she said, can bring up similar feelings." Here is an interesting and helpful article from the NY Times on how to clean and organize your digital life: How to Clear Out Digital Clutter - The New York Times (gift article)

The Hottest Peppers in the World

Curious about where your favorite pepper ranks? Here you go... Hottest Pepper in the World and 6 Other Spicy Chilis

Artificial Sweetener Associated with Cardiovascular Events

This week's study in Nature Medicine, The artificial sweetener erythritol and cardiovascular event risk,, demonstrates an association between the use of erythritol and cardiovascular events such as stroke or heart attack. More research is needed. Zero-Calorie Sweetener Possibly Linked to Heart Issues, New Study Suggests (gift article)

The Microbiome and Multiple Sclerosis (pre-clinical)

These scientists are investigating how the microbiome might be manipulated as a therapeutic intervention in Multiple Sclerosis: Bile acids and gut microbes could potentially treat multiple sclerosis, according to new research in mice

Cannabinoids and Cancer

As North Carolina ponders approval of medical marijuana, these scientists are investigating how cannabinoids might be used as therapeutic agents to combat cancer: Can Cannabis Help Treat Cancer? Researchers Are Getting Closer To An Answer

GLP-1 Agonists in Economist

The Economist had a brief but informative overview of the new anti-obesity drugs. A new class of drugs for weight loss could end obesity (subscription required)

The Problem of Fraud in the Scientific Literature

The problem of fraudulent papers in medicine is much more prevalent than I believed. The Economist explains There is a worrying amount of fraud in medical research (subscription required)

Wired Guide to Quantum Computing

Wired continues its excellent series on the hottest technology topics: What Is Quantum Computing? The Complete WIRED Guide

Generative AI does Anime

Unlike the author of this article, I was fascinated by the techniques used with generative AI to make an anime from the video: Corridor Crew's AI-Generated Anime Isn't Just Callous and Craven — It's Also Dangerous Make sure to watch the linked videos in the story.

Words, Not Truths

"On the other hand, if I can talk to a bot that will give me plausible responses to things I say, it would be useful in situations where factual accuracy isn't all that important." A computer scientist chimes in on how he believes generative AI, such as ChatGPT, should be used: ChatGPT is great – you're just using it wrong

Why Some Food Tastes Better the Next Day

Here is some of the science behind why certain leftovers taste better the next day: Why certain foods taste better the next day