CVS

071 - Bitter Truths, F-Bombs, and Twinning - HealthHippieMD Week In Review

Twinning to Understand the Impact of Food

New research published in JAMA Network Open involved identical twins on an eight-week dietary trial comparing vegan and omnivorous diets. The vegan group experienced notable health benefits: a 10-15% reduction in LDL cholesterol, 25% lower insulin levels, and a 3% weight loss. This study, unique for using genetically identical twins, highlighted the efficacy of a plant-based diet in improving cardiovascular markers and suggested even partial dietary shifts away from animal products can be beneficial. The findings underscore the potential health advantages of vegan diets while acknowledging the challenges of dietary changes. One identical twin went vegan while the other didn't. See what happened | CNN.

The Rising Tide of Autoimmunity

The article Autoimmunity Has Reached Epidemic Levels. We Need Urgent Action to Address It | Scientific American highlights the alarming increase in autoimmune diseases, now considered an epidemic. It emphasizes the urgent need for action to address this growing health crisis. Autoimmune conditions, where the immune system mistakenly attacks the body, affect an increasing number of people worldwide. The article calls for more research, better public awareness, and improved healthcare strategies to combat these diseases. It underscores the importance of understanding environmental triggers and genetic factors contributing to this surge, advocating for a comprehensive approach to tackle the autoimmune epidemic

A Bitter Truth

"Artificial sweeteners were originally intended to stave off the increasing obesity and metabolic disease epidemic, but instead, they may have directly contributed to it." Artificial Sweeteners May Have Despicable Impacts on Gut Microbes - Scientific American Blog Network delves into the potentially harmful effects of artificial sweeteners on gut microbes. It highlights a study suggesting that these sugar substitutes can inhibit the growth of certain beneficial gut bacteria. This disruption may lead to negative health consequences, as a healthy gut microbiome is crucial for overall well-being. The article underscores the importance of further research to fully understand the impact of artificial sweeteners on our gut health and the broader implications for our diet and lifestyle choices.

AI Travel Tips

Who has "packing a suitcase" on their valuable applications of AI Bingo Card? I certainly didn't. AI Teaches Robots the Best Way to Pack a Car, a Suitcase--Or a Rocket to Mars | Scientific American.

What Ails the NHS

Many people (including me) believe a single-payer system is the only way out of the United State's current healthcare morass. Detractors often point to the issues facing Britain's National Health Service (NHS). The New York Times had an interesting opinion on the origins of the current problems with the British System. As with everything in healthcare, the issue is far more complicated than it first appears: Opinion | Britain Ruined One of the Best Healthcare Systems in the World - The New York Times (gift article).

CVS's New Prescription for Pricing

CVS Health has announced a significant shift in pricing prescription drugs, aiming to simplify and make a traditionally complex system more transparent. Set to launch on January 1, 2025, for commercial payers, the new model, named CVS CostVantage, will calculate drug prices and pharmacy reimbursements using a precise formula. This formula includes the cost of the drug, a defined markup, and a dispensing fee. While this change may not uniformly reduce the cost of all medications, it is expected to generally lower prescription costs for consumers, employers, and health insurers. This initiative follows years of criticism over the U.S. healthcare system's lack of clarity and inflated prices. CVS's move mirrors a similar approach by Mark Cuban's online pharmacy, Cost Plus Drugs, which also aims to reduce medicine prices by selling them at a set markup over cost, plus pharmacy fees. Count me as skeptical that the change will benefit consumers. CVS Says It Will Change the Way Its Pharmacies Are Paid - The New York Times (gift article).

Scientific Grounds

A recent study has brewed up a simple yet effective solution to the messy business of coffee grinding. The research, focusing on the role of moisture in reducing static electricity in coffee grounds, found that a spritz of water on beans before grinding can significantly reduce static. This makes for a tidier grinding process and results in a more consistent and stronger-tasting espresso shot. The study, published in the journal Matter, is a part of the growing field of coffee science, which combines diverse disciplines to enhance our understanding of coffee preparation. Interestingly, the collaboration began through a shared interest in electric charge buildup, a common thread between coffee grinding and volcanic eruptions. This interdisciplinary approach led to the discovery that moisture levels in coffee beans play a crucial role in how they accumulate electric charge during grinding, with lighter roasts gaining less static due to higher internal moisture. The practical takeaway from this study is clear: a little water can go a long way in improving both the cleanliness of coffee grinding and the quality of the brew. There's a better way to grind the coffee, according to science - The Washington Post (gift article).

F-Bombs

Expletive use is on the rise. I present to you A very short history of the F-word - Big Think.

Present Tense

"Traumatic memories are not experienced as memories as such," but as "fragments of prior events, subjugating the present moment." A recent study in Nature Neuroscience delves into the unique neural mechanisms of traumatic memories, which may illuminate why they are so vivid and intrusive. Researchers at Yale University and the Icahn School of Medicine at Mount Sinai conducted brain scans on 28 individuals with PTSD, analyzing their responses to recorded narrations of their memories, ranging from neutral to traumatic. The study revealed that traumatic memories engage the posterior cingulate cortex, a brain area typically involved in introspection or daydreaming. This groundbreaking research offers new insights into the workings of PTSD, suggesting that traumatic memories are processed as ongoing experiences, thereby explaining their persistent and disruptive nature in everyday life. Brain Study Suggests Traumatic Memories Are Processed as Present Experience - The New York Times (gift article).

Harvard's Morgue Mystery

In a shocking scandal at Harvard, the Anatomical Gift Program, where people donate their bodies for scientific study, was exploited for a macabre trade. Cedric Lodge, the morgue manager, along with several others, was indicted for stealing body parts and selling them to oddity collectors. Families who had donated their loved one's body were horrified to discover that the remains might have been part of this gruesome trade. This betrayal of trust at such a prestigious institution has left many in disbelief and mourning, questioning the integrity of body donation programs and the dark underbelly of oddity collecting. Inside The Harvard Morgue Scandal: Missing Body Parts, Mourning Families.

011 - CVS, Amazon, and the Disruption of Primary Care, Anxiety Inoculants, Wabi Sabi, and AI. - HealthHippieMD Week In Review

Wabi Sabi - An Inoculant for Perfectionism

Perfectionism can have a devastating effect on mental health. The Japanese concept of wabi-sabi can help: Escape the perfectionist trap with the philosophy of "wabi-sabi"

CVS, Amazon, and the Disruption of Traditional Primary Care

Traditional primary care practices and healthcare systems should be quaking in their boots. The article CVS, Amazon Deals Might Be Good for Patients, Bad for Primary Care, gives the good and bad of the disruption of healthcare. We are in the early days of this transformation that will include technology and place a much greater emphasis on preventative care/wellness. Exciting times!

+For some of the challenges, see this article extracted from a recent Harvard Business Review: Amazon's Foray into Primary Care Won't Be Easy "....a fundamental question looms: Can profit-driven entrepreneurship and bottom-up innovation make the U.S. health care system work anywhere nearly as well as those in places like France, Sweden, Norway, Australia, the Netherlands, New Zealand, Germany, and Switzerland? They may be relatively dull, but they keep people healthy at an affordable cost.".

How to be Bold

Anxiety short-circuits many decision-making processes for a wide range of the population. The article How to Be Bold discusses the implications and how to overcome anxiety inertia. Thanks, Laura!

Fasting and Cancer

I am interested in extending lifespan and health span, so I have read many papers on caloric restriction. Fasting to combat cancer is somewhat controversial but gaining momentum. Dr. Michael Gregor over at NutritionFacts has a great series of introductory videos for you:

+For a decent scientific review on caloric restriction and cancer, see this 2018 paper from Valter Longo's Lab: Starvation, Stress Resistance, and Cancer

Immersive Rights in the Metaverse

The Metaverse, "a broad societal shift in how we engage digital content, going from flat media viewed in the 3rd person to immersive experiences engaged in the 1st person," is coming, ready or not. As with all powerful technologies, we must consider their use and implications. The article The case for demanding "immersive rights" in the Metaverse touches on many of the potential issues. This article reminded me of some of the early warnings on the use and potential abuse of social media.

Immersive Virtual Environments Eases Pain During Hand Surgery

The article, Gaming tech could ease pain during surgery, reports the findings of a recent preliminary study looking at the effects of immersive VR on surgical pain: Virtual reality immersion compared to monitored anesthesia care for hand surgery. Adding this to my reading list.

Life Lessons Gleaned from Free Soloing El Capitan

The advice and life lessons came rapidly in the podcast, How free solo climber Alex Honnold faces fear. The interviewer, Adam Grant, an organizational psychologist at Penn, was positively giddy during the interview. This episode is well worth your time.

Rethinking Alzheimers

Last week I mentioned the re-examination of a foundational paper whose findings have been questioned. That re-examination, coupled with the little to no progress in the prevention or treatment of the disease, has led to renewed interest in alternate theories. The article Alzheimer's Might Not Be Primarily a Brain Disease, examines some of the leading alternate views.

A panel of experts gathered by the U.S. Department of Health and Human Services issued a draft guidance this week recommending all adults 65 and younger are screened for anxiety: Health Panel Recommends Anxiety Screening for All Adults Under 65. One of the issues mentioned is what the U.S. will do with the increased volume of newly diagnosed anxious adults. The mental health infrastructure was inadequate before the pandemic. During the pandemic, the existing volume of patients struggled to find licensed mental health providers. It is unlikely the system will be able to keep up with all the newly diagnosed patients in need of services.

Stool Banking - Your Poop May Hold the Secret to Longevity

As we learn more about the microbiome and the aging process, the two are intertwined--especially around inflammation. Ten years ago, when trying to convince my chairman about the importance of this emerging area, I remember telling him that as we learn how important the microbiome is to health and wellbeing, the inevitable outcome would be the prevalence of personal stool banking. The article Your Poop May Hold the Secret to Long Life focuses on the logistical and ethical questions surrounding storing your stool.

Eric Topol

Eric Topol is constantly tweeting out fantastic resources. My favorite finds from this week:

Humans Evolved with their Microbiomes

The gut microbiome plays many vital roles in health and well-being. Humans evolved with their microbiomes, and like genes, gut microbes pass from one generation to the next discusses the co-evolution of humans and their microbial passengers.

The Search for New Pain Medication

The Economist had a great article on the search for new analgesics: Better medicines are needed to relieve pain

Quote of the Week

"Blind belief in authority is the greatest enemy of truth." - Albert Einstein.