Non-Nutritive Sweeteners

118 - Kindness, Humor, and Maple Syrup - HealthHippieMD Week In Review

Small Acts, Big Ripples

An upward spiral – how small acts of kindness and connection really can change the world, according to psychology research explores how small, intentional acts of kindness and connection can catalyze societal change. Drawing on psychology, the author highlights how collective “micro-activism” combats hopelessness by addressing cognitive dissonance and fostering empathy. Studies reveal that personal connections soften prejudices, shift attitudes, and strengthen communities, ultimately influencing societal structures. From bridging political divides to improving intergroup relations, Hinchey demonstrates the transformational potential of everyday compassion. By building intentional relationships, individuals spark a powerful “upward spiral” of positive change, proving that small actions can create impactful global ripples.

Why Humor Is Serious Business

According to psychologists, humor serves as an unconscious yet strategic coping mechanism, transforming stress into moments of joy and connection. By triggering laughter, it enhances creativity, broadens perspective, and offers physical benefits like improved breathing and relaxation. Socially, humor fosters bonds, yet it requires mindful application—misplaced or mean-spirited jokes can deepen divides. Experts caution against toxic positivity, suggesting humor be used in moderation, providing emotional reprieve while still processing life’s challenges. Ultimately, humor acts as a psychological balm, equipping us with “antibodies” to weather hard times.How Humor Can Help You Get through Hard Times | Scientific American.

The Science of Chuckles and Tickles

A study by Roza Kamiloglu at the Free University of Amsterdam identifies two core types of human laughter: tickling-induced and laughter sparked by everything else. Using 887 video samples and machine learning, researchers found that tickling laughter has unique acoustic traits that make it more recognizable, a feature possibly tied to its evolutionary roots in primate play and bonding. Unlike other laughter forms, which evolved later with human cognition, tickling laughs date back over 10 million years. These findings illuminate laughter’s role in social connection and its potential infectiousness. The two types of human laugh.

Sweet or Sour? The Truth About Sugar Substitutes

As consumers seek to reduce sugar intake, food manufacturers increasingly use artificial and natural sugar substitutes, such as stevia, monk fruit, and allulose, to meet demand. While these alternatives promise fewer calories, experts caution about their health implications. Research links artificial sweeteners to potential risks, including cancer, heart disease, diabetes, depression, and gut health issues. New “natural” substitutes may seem safer, but their long-term effects remain uncertain. Moderation is key, with experts advising reduced reliance on processed foods and careful label scrutiny to limit hidden sweeteners. Ultimately, a balanced diet of whole foods is the safest choice. Are newer sugar substitutes better for you than artificial sweeteners? - The Washington Post (gift article).

Sweet Benefits of Maple Syrup for Health

A clinical trial (partially sponsored by the Maple Syrup Industry) reveals that swapping refined sugars for maple syrup improves cardiometabolic health, reduces abdominal fat, and enhances gut microbiota. Published in The Journal of Nutrition, the study highlights maple syrup’s natural compounds, including anti-inflammatory polyphenols, which lower blood sugar, systolic blood pressure, and harmful gut bacteria while increasing beneficial strains. Participants consuming two tablespoons daily experienced notable health improvements over eight weeks. Researchers aim to expand these findings, solidifying maple syrup as a “smarter sweetener” and an effective tool in preventing metabolic diseases like diabetes and cardiovascular issues. Reducing Abdominal Fat: Researchers Uncover Surprising Health Benefits of Maple Syrup. (Thanks, Amy!).

How Fear Shapes Your Choices

Loss aversion, a cognitive bias rooted in human psychology, compels us to avoid losses rather than seek equivalent gains, often leading to risk aversion and suboptimal decisions. Stemming from evolutionary survival mechanisms, this bias influences various aspects of life, from investments to career choices. How Loss Aversion Controls Your Decisions Without You Knowing It explores its impact on decision-making, highlighting cases like Polaroid’s failure to adapt and the sunk cost fallacy’s grip. Strategies to counteract loss aversion include reframing outcomes, quantifying risks, conducting pre-mortem analyses, and building emotional resilience, enabling more balanced, growth-oriented decisions.

Brain Gains with a Little Strain

A Penn State study reveals that even light physical activity, such as walking or playing, can enhance cognitive processing speed, reversing four years of cognitive aging. By tracking 204 middle-aged adults through smartphone check-ins over nine days, researchers found mental speed improved after participants engaged in any physical activity, regardless of intensity. The findings suggest movement, not vigorous exercise, as the key to cognitive boosts. While the long-term effects remain uncertain, ongoing research aims to explore how daily habits influence brain health and dementia prevention, using cutting-edge digital tools to deepen understanding. Light exercise can yield significant cognitive benefits, new research shows.

ChatGPT Diagnoses Better than Doctors

A study revealed ChatGPT’s diagnostic prowess surpassed physicians, even when doctors used the chatbot. While ChatGPT achieved a 90% accuracy rate on medical case histories, doctors averaged 74-76%, highlighting overconfidence and underutilization of AI. Researchers noted doctors often disregarded ChatGPT’s insights, contradicting their initial assumptions. The findings underscore the untapped potential of AI as a “doctor extender,” emphasizing the need for better integration and training. Though AI’s linguistic models shine in diagnosis, the human-AI collaboration still faces hurdles rooted in trust and adaptation to technology’s full capabilities. ChatGPT Defeated Doctors at Diagnosing Illness - The New York Times (gift article).

Keep Calm and Carry On (Mindfully)

How to Stay Calm When the World Is in Chaos | Psychology Today, although written in 2020, is equally applicable today. The article explores strategies for maintaining composure in an increasingly chaotic world. It emphasizes acknowledging fear without letting it dominate, living with intention, and fostering inner peace. Suggestions include limiting exposure to anxiety-inducing news, setting boundaries with people who amplify distress, and taking small, meaningful actions to feel empowered. The piece highlights the role of mindfulness, particularly meditation, as a tool to anchor oneself in the present and reduce catastrophizing thoughts. Seeking support from trusted individuals or professionals is encouraged, reinforcing that while change is inevitable, inner resilience can help navigate uncertainty.

Tune Up Your Memories

Listening to music can change how you remember past events - The Washington Post (gift article) reveals how music can remix your memories, shifting their emotional tone. Research from the Georgia Institute of Technology shows that listening to emotionally charged music during memory recall can reshape how those moments are remembered. Brain scans revealed enhanced activity in emotional and memory-processing regions, suggesting music’s power to intertwine with and reframe past events. These findings open new possibilities for music-based therapies, particularly for PTSD and depression. Everyday soundtracks, too, might uplift your mood and subtly transform how you recall life’s moments in the future.

103 - Erythritol Issues, Diet over Drugs for I.B.S., and Preventing Cancer - HealthHippieMD Week In Review

The Risky Truth Behind Erythritol

A recent study reveals that erythritol, a popular sugar substitute found in products like Truvia and Splenda, may increase the risk of heart attack and stroke by elevating platelet activity, which can lead to blood clot formation. The study compared erythritol with sugar and found that while sugar did not affect platelet activity, erythritol significantly did. Despite being classified as “generally recognized as safe” by the F.D.A., this research calls for further long-term studies to assess the cardiovascular risks of erythritol and similar sugar substitutes. This Popular Sugar Substitute May Put Your Heart at Risk, A New Study Reveals.

Rolling Towards Relief

The F.D.A. is nearing a decision on the approval of MDMA-assisted therapy for treating PTSD, a move that could revolutionize psychedelic medicine. This potential approval has sparked a bipartisan lobbying effort from veterans, lawmakers, and researchers, advocating for the drug’s benefits despite concerns over trial data. The therapy, combining MDMA with talk therapy, has shown promising results in reducing PTSD symptoms, but challenges remain, including the stigma surrounding psychedelic drugs and the need for rigorous data. The F.D.A.’s decision could set a precedent for future treatments in the burgeoning field of psychedelic medicine.Veterans and Lawmakers Lobby for Approval of MDMA Therapy - The New York Times (gift article).

+despite the lobbying by some powerful groups, the F.D.A. did not approve MDMA: F.D.A. Officially Rejects MDMA-AT as PTSD Treatment | DoubleBlind Mag.

The Lingering Toll

A recent global study estimates that 400 million people have experienced long-term COVID-19, highlighting the ongoing and severe impact of the condition. With only 7-10% of patients recovering fully within two years, long Covid poses significant challenges for healthcare systems and economies, costing an estimated $1 trillion annually. The report stresses the need for more research into treatments and biological mechanisms while recommending policy changes to support affected individuals. The study underscores the far-reaching effects of long-term COVID-19 on individuals’ lives, work, and communities. About 400 Million People Worldwide Have Had Long Covid, Researchers Say - The New York Times (gift article).

Gender Prescription

Recent research suggests that patients under the care of female doctors have better outcomes than those treated by male doctors. This trend, observed across multiple countries, remains puzzling despite consistent data supporting it. Various factors, such as attentiveness to symptoms and quality of care, are posited as reasons, but the exact cause of this gender discrepancy is still unclear. While the findings provoke thought, they also underline the need to explore how gender influences medical care quality and patient survival rates. Do women make better doctors than men? (gift article).

Beyond the Scale

GLP-1 agonists like semaglutide and tirzepatide, known for their weight loss effects, reveal broader health benefits. Initially developed for diabetes, these drugs show promise in enhancing heart health, protecting kidneys, reducing sleep apnea, and even combating addiction and cognitive decline. Clinical trials highlight their potential to lower cardiovascular risks, reduce inflammation, and support brain health, suggesting these medications may act on multiple body systems beyond weight control. As research progresses, GLP-1 drugs could redefine their role in health promotion, not just weight loss.The Benefits of Ozempic Are Multiplying | WIRED.

Parasites as a Neurological Delivery System

Scientists are exploring using the parasite Toxoplasma gondii as a novel drug delivery system for brain diseases. The blood-brain barrier often prevents effective treatment of neurological conditions, but Toxoplasma naturally crosses this barrier. Researchers have engineered the parasite to deliver therapeutic proteins directly into neurons, potentially offering new treatments for disorders like Rett syndrome. However, the inherent risks of Toxoplasma infection, including its link to neurological issues, present significant challenges before this method can be used in clinical settings. Ick. How Do You Get Drugs to the Brain? Maybe Try a Parasite | WIRED.

Mind Games

Are You Psychic? Nudge, Nudge explores the concept of “population stereotypes,” a psychological phenomenon that explains how predictable human responses can create the illusion of telepathy. Through engaging examples, the author demonstrates how large groups of people consistently choose certain numbers and symbols, making it appear as though psychic abilities are at play. The article delves into the history of these demonstrations, including Uri Geller’s famous televised telepathy act, and uncovers how understanding these patterns can debunk claims of paranormal activity.

Preventing Cancer

# I’m an oncologist. Here’s what I do to reduce my own cancer risk (gift article) explores five practical steps to reduce cancer risk, emphasizing the importance of modifiable behaviors. Key strategies include vigilant sun protection to minimize U.V. exposure, limiting alcohol intake to reduce various cancer risks, abstaining from smoking to lower the likelihood of lung and other cancers significantly, incorporating daily exercise to lower risks of several cancers, and maintaining a balanced diet by avoiding sugary drinks, fast food, and processed meats. While some cancer risks are unavoidable, these proactive measures can play a significant role in prevention.

Diet Beats Drugs for I.B.S. Relief

Irritable bowel syndrome (I.B.S.) is a challenging condition with symptoms like abdominal pain, bloating, and irregular bowel movements. Traditional treatments often include medications like laxatives and antidepressants. However, a new study published in The Lancet highlights that dietary changes, specifically a low-FODMAP diet, may offer more effective symptom relief than medication. This approach, which involves avoiding certain carbohydrates that trigger symptoms, is gaining recognition as a powerful tool in managing I.B.S. for many sufferers. What’s the Best Way to Treat I.B.S.? - The New York Times (gift article).

100 - Tidy Conversations, Sweat, and Grim Reaping- HealthHippieMD Week In Review

In honor of my 100th newsletter, would you please do me a favor and forward this emair to at least one interested friend? Thank you!

Ozempic Your Brain

A recent study in Lancet eClinical Medicine suggests that semaglutide, the active ingredient in Ozempic, might lower the risk of cognitive decline and dementia in type 2 diabetes patients. Analyzing data from over 100,000 patients, researchers found those on semaglutide had lower rates of cognitive issues compared to those on other diabetes medications. While the findings show a significant link, they do not establish causation, prompting calls for further clinical trials. Experts believe Ozempic's neuroprotective effects, anti-inflammatory properties, and enhanced glucose utilization in the brain may contribute to these promising outcomes. Study: Ozempic Could Lower Dementia Risk, Cognitive Decline.

Tidy Conversations

How to talk to aging parents about downsizing and decluttering - The Washington Post (gift article) discusses the delicate process of talking to aging parents about downsizing and decluttering. It emphasizes the importance of approaching the conversation with empathy, respecting parents' autonomy, and setting clear intentions. Experts suggest initiating discussions by posing neutral questions and involving parents in decision-making. The process should be gradual to avoid overwhelming parents and ensure meaningful items aren't discarded. Tips include categorizing items, using sticky notes for organization, and considering the sentimental value of belongings. The article also advises how to navigate unwanted heirlooms and the benefits of donating items to meaningful organizations.

Pancreatic Cancer's Silent Switcheroo

Recent research reveals pancreatic cancer's cunning strategy: it deactivates a crucial gene, HNF4A, via DNA methylation, allowing rapid growth and spread. This aggressive cancer, often detected too late, has a bleak prognosis, with over half of patients dying within three months of diagnosis. Scientists emphasize the urgency of understanding this mechanism to develop better treatments. The study highlights how HNF4A loss contributes to cancer's severity, offering insights that could pave the way for future, more effective, less invasive therapies. Pancreatic Cancer Turns Off a Key Gene In Order to Grow | WIRED.

AI vs. AI

The article discusses a novel method where one AI language model interrogates another to detect inaccuracies, known as hallucinations, in AI responses. These hallucinations range from harmless errors to potentially dangerous mistakes in critical areas like medical advice. Researchers have developed a system where a second AI checks the consistency of multiple answers from the first AI, identifying outliers to spot inaccuracies. This method improves detection accuracy but comes with high energy costs and needs to be foolproof, highlighting the ongoing challenges in AI reliability and accuracy. Can One Chatbot Catch Another's Lies? | Scientific American.

Meat the Future

Researchers are closing the gap between lab-grown and conventional beef by enhancing cultured meat with compounds from the Maillard reaction responsible for cooked meat's savory flavors. This advancement, published in Nature Communications, allows lab-grown meat to release authentic beefy aromas at high temperatures. By integrating furfuryl mercaptan and other Maillard products into a hydrogel scaffold, the team achieved a flavor profile closer to natural beef. This breakthrough could improve public perception and scalability of cultured meat, paving the way for a more sustainable and cruelty-free alternative to traditional meat. Lab-Grown Meat Is Getting Closer to Tasting Like Real Beef | Scientific American.

Sweet and Low-Down

Since their debut in the 1950s, artificial sweeteners have promised to curb the cravings of America's sweet tooth without the calorie count of sugar. These sugar substitutes are now widespread in diet sodas, breads, yogurts, and even coffee. However, their safety has been under scrutiny for decades. Research remains inconclusive and sometimes contradictory, leaving many questions about their health impacts. Despite widespread use, experts like Dr. Dariush Mozaffarian from Tufts University argue that more human studies are needed to understand their benefits and risks fully. Are Artificial Sweeteners Safer Than Sugar? - The New York Times (gift article).

Truth About Sweat

In Stop Feeling Bad About Sweating | TIME, author Sarah Everts delves into the misunderstood world of perspiration. Sweating, often maligned and masked by whole-body deodorants, is a remarkable cooling mechanism that sets humans apart in the animal kingdom. While marketing tactics exploit our insecurities, encouraging the overuse of deodorants can disrupt our skin's microbiome. Beyond its cooling function, sweat plays a role in personal scent identity, which fosters emotional connections. Embracing our natural sweat can shift the narrative from shame to acceptance, recognizing its vital role in survival and social bonds.

Weight a Minute: Rethinking the Obesity-Health Link

Researchers have identified a phenomenon called metabolically healthy obesity (MHO), where individuals classified as obese based on their BMI exhibit no health issues typically associated with obesity, such as high blood pressure or insulin resistance. This condition challenges the traditional notion that obesity inherently leads to poor health. Studies reveal that 6% to 60% of obese adults could be metabolically healthy, suggesting the need to reconsider the stigmatization of larger body sizes and the accuracy of BMI as a sole health metric. Understanding MHO may help destigmatize larger bodies and promote a more nuanced view of weight and health. People Who Are Fat and Healthy May Hold Keys to Understanding Obesity | Scientific American.

Vax to the Future: Shots Lower Long Covid Odds

A new study published in The New England Journal of Medicine confirms that COVID-19 vaccines significantly reduce the risk of developing long-term COVID-19. Researchers analyzed the health records of nearly 450,000 Covid-infected individuals and over 4.7 million non-infected people in the U.S. Veterans Affairs health system. Findings reveal that vaccinated individuals had a much lower incidence of long-term COVID-19 than their unvaccinated counterparts. Despite this, a residual risk remains for vaccinated people, suggesting that while vaccines mitigate long-term COVID-19, they don't eliminate it. Vaccines Significantly Reduce the Risk of Long Covid, Study Finds - The New York Times (gift article).

Grim Reaping the Benefits

Contemplating death, or "memento mori," can enrich our lives by highlighting the importance of living fully. In her book "You Only Die Once," Jodi Wellman argues that acknowledging our mortality can lead to a more meaningful and vital existence. By considering "temporal scarcity," we value our limited time more. This perspective encourages prioritizing what truly matters and helps avoid regrets. Positive psychology supports this duality of appreciating life's joys alongside its inevitable hardships. Embracing death reminders, like counting our remaining Mondays, can inspire us to live more purposefully and joyfully. Memento mori: Why thinking about death enriches your life - Big Think. +see also: "Memento Mori": The Reminder We All Desperately Need.

094 - When Drugs Go Wild, Dodging Microplastics, and The Brain's Fear Gear - HealthHippieMD Week In Review

The Brain's Fear Gear

A recent study, published in Science, elucidated a chemical "switch" in the brainstem's dorsal raphe nucleus of mice that converts stress into fear by altering neurotransmitter release, leading to anxiety disorders and PTSD. This switch involves neurons shifting from releasing glutamate to GABA. Experiments showed that blocking GABA synthesis or using fluoxetine (Prozac) could prevent generalized fear responses. Post-mortem studies on human PTSD patients confirmed this mechanism, opening avenues for targeted treatments. Understanding these molecular processes provides a pathway for developing specific interventions for stress-induced fear and related disorders. The brain's "switch" that puts fear into overdrive - Big Think

Put the 230 Genie Back in the Bottle

The article argues for reforming Section 230 of the Communications Decency Act, which protects online platforms from liability for user-generated content. Originally intended to encourage moderation of harmful content, Section 230 has instead enabled the spread of misinformation, online harassment, and social polarization. The article suggests a "notice-and-takedown" approach and other modifications to hold platforms accountable while preserving the law's benefits. Reform is necessary to mitigate the negative impacts on social discourse and restore some responsibility to the internet. It's Time to Restore Some Sanity to the Internet-Mother Jones.

A Trip Full of Pitfalls

MDMA's approval for PTSD treatment faces significant hurdles after an FDA advisory panel voted against recommending approval due to issues like biased self-reporting and inconsistent psychotherapy standards. The "unblinding" effect, where participants likely knew if they received MDMA or a placebo, raises concerns about the validity of positive outcomes. Allegations of therapist misconduct and insufficient monitoring of side effects further complicate the case. With the FDA's decision pending, the future of MDMA-assisted therapy remains uncertain, highlighting the challenges in proving the efficacy and safety of psychedelic treatments. The panel's decision will slow but likely not dampen interest in the use of psychedelics for mental health. "In many ways, we're creating a new field of medicine," said Lykos' senior medical director, Alia Lilienstein. The Case for MDMA's Approval Is Riddled With Problems | WIRED.

The Potential of Psychedelics

Gül Dölen, a neuroscientist and psychiatric researcher at the University of California, Berkeley, discusses the surprising potential of psychedelics to change the lives of those grappling with addiction, depression, and post-traumatic stress. A must-listen if you're curious about psychedelics and before you get too discouraged by the FDA Panel's decision this week. ‎The Joy of Why: Can Psychedelics Improve Mental Health?

Xylitol's Hidden Risks

Recent research highlights a concerning link between the popular sugar substitute xylitol and an increased risk of heart attack and stroke. While xylitol is widely used for its dental benefits and low-calorie content, new findings suggest potential cardiovascular dangers. This revelation urges caution for those seeking healthier sweetener alternatives, emphasizing the need for further investigation into xylitol's long-term effects on heart health. Xylitol Increases Heart-Health Risks (Thanks, Dave - NextDraft).

When Drugs Go Wild

Modern drug pollution is transforming wildlife, with meth-addicted trout, fearless perch, and sex-changed fish among the casualties. Pharmaceuticals like antidepressants and contraceptives, entering ecosystems via inadequate waste treatment, are altering animal behavior and physiology. Diclofenac, an anti-inflammatory, caused a dramatic decline in India's vultures, leading to increased rabies from unconsumed cattle carcasses. Experts urge urgent reform in drug design to mitigate these unintended ecological impacts, emphasizing that the same properties that make drugs effective in humans pose severe risks to biodiversity. Environmental exposure to pharmaceuticals is a pressing global issue demanding immediate attention. Meth-addict fish, aggro starlings, caffeinated minnows: animals radically changed by human drugs. (Thanks again Dave-NextDraft).

Food Waste Unpeeled

America's apple obsession reveals the broader issue of food waste. Despite producing 4.36 million metric tons of apples annually, a significant portion rots due to factors like overproduction and market fluctuations. This waste is emblematic of a more substantial problem, with 30-40% of all food in the U.S. wasted, equating to 133 billion pounds annually. The waste spans all stages of food production, exacerbated by weather, inefficient storage, and consumer habits. Innovations like controlled-atmosphere storage and advocacy from groups like The Farmlink Project show promise, but systemic change is essential to curb this massive loss and its environmental impact. America's Favorite Fruit Reveals The Hidden Truth About Food Waste.

+See Also: The Rotten Secret Plaguing America's Grocery Stores.

An Operating Room "Black Box."

Teodor Grantcharov's AI-powered "black box" aims to revolutionize surgical safety by recording and analyzing all OR activities. The technology captures everything from instrument use to environmental factors, offering a comprehensive view of operations. Despite the potential for significant improvements in safety and efficiency, the system faces resistance due to privacy concerns and fear of legal repercussions. Hospitals are divided between leveraging this data for quality improvements and managing the overwhelming influx of information. As the black box spreads, it promises a new era of transparency and enhanced patient care. This AI-powered "black-box" could make surgery safer | MIT Technology Review. (paywall).

Dodging Microplastics

Microplastics in food, air, and household items pose potential health risks. To minimize exposure, opt for less processed foods, use glass containers, avoid heating plastics, and switch to loose-leaf tea. Limit plastic use in furniture and clothing; frequent vacuuming with a HEPA filter and damp cloths can reduce indoor microplastics. Choose reusable water bottles and consider laundry solutions like special filters or washing less often. While complete avoidance is impossible, making informed choices can reduce microplastic intake, emphasizing the importance of manageable, everyday actions.How to Minimize Your Exposure to Microplastics - The New York Times (gift article).

088 - Fasting, Happiness, and the Skin-Gut Axis - HealthHippieMD Week In Review

A.I. Designs New Tools for DNA Editing

The realm of CRISPR gene editing is experiencing a technological revolution with the introduction of generative A.I. Profluent, a startup based in Berkeley, California, has unveiled an A.I. system that crafts blueprints for novel gene editing tools. This innovation, which employs methods similar to those driving the popular A.I. chatbot ChatGPT, can enhance the precision and speed of combating illnesses and diseases. Profluent's A.I. analyzes vast amounts of biological data to create gene editors that could surpass those formed through natural evolution. Their recent creation, OpenCRISPR-1, has already been used to edit human DNA and is now freely available for further experimentation. This breakthrough could herald a new era of medical treatments, tailor-made at unprecedented speeds. Generative A.I. Arrives in the Gene Editing World of CRISPR - The New York Times (gift article).

Skin-Gut Axis

Researchers at the University of California San Diego have discovered that skin injuries can significantly affect gut health in mice. This study reveals a skin-gut axis, showing that damage to the skin disrupts the intestinal defenses and alters the gut microbiome. The findings challenge the traditional belief that gut microbes primarily influence skin health, instead highlighting a bidirectional relationship. The experiments demonstrated that skin wounds and artificial increases in skin-specific enzyme levels led to more severe colitis, a gut disorder, by altering the microbial balance. This research, published in Nature Communications, suggests a new perspective on the interplay between skin injuries and gut health, with implications for understanding human diseases. A Skin-Deep Wound Can Trigger Gut Bacteria Changes: ScienceAlert (thanks, Amy).

Fever Dreams

Fever dreams, typically vivid, intense, and disturbing, are often a part of the ill experience when body temperature rises due to sickness. These dreams are characterized by bizarre, repetitive, and negative imagery, influenced by altered brain neurochemistry and rapid eye movement (REM) sleep disturbances. Research indicates these dreams often feature surreal scenarios and threatening elements, such as oversized creatures or menacing figures. Experts suggest fever-induced alterations in body and brain function could trigger these dreams, which also hold psychological significance, potentially representing inner fears or conflicts. While generally harmless, persistent fever dreams should be discussed with a healthcare provider as they could signal underlying health issues. What Does It Mean to Have a Fever Dream?

Fasting Time

Could a Calorie-Restricted Diet or Fasting Help You Live Longer? - The New York Times delves into the scientific intrigue surrounding calorie restriction and intermittent fasting as potential longevity boosters, a concept borne from decades of animal research. Studies suggest that cutting calorie intake can significantly extend the lifespan of various species, from worms to monkeys, by inducing key biological changes and reducing susceptibility to age-related illnesses like cancer. However, the application of these findings to human longevity remains uncertain. Although some evidence hints that these dietary adjustments could benefit human metabolic health and potentially slow aging, definitive long-term human studies are lacking, and the mixed results, including some contrary findings in human obesity, prompt ongoing debate among scientists.

Fact or Fiction

Chatbot answers are all made up. This new tool could help you figure out which ones to trust. | MIT Technology Review discusses a new tool developed by A.I. startup Cleanlab, aimed at evaluating the reliability of responses from large language models (LLMs). This tool, emerging from a quantum computing lab at MIT, scores outputs from LLMs on a scale from 0 to 1 to determine their trustworthiness, addressing businesses' concerns about these models' tendency to "hallucinate" or generate inaccurate information. By providing a reliability score, the tool allows users to discern which responses to trust. This innovation is especially pertinent as chatbots become more integrated into daily digital interactions, from search engines to office software. The Trustworthy Language Model could significantly reduce the risk of using LLMs in high-stakes business environments, enhancing their appeal and utility.

Sweet Nothings

In a recent article from The Atlantic, the introduction of brazzein, a new sugar substitute, is explored alongside older alternatives like aspartame and stevia. Despite its promise, brazzein must replicate sugar's unique sweetness, much like its predecessors. The narrative recounts a personal journey of managing blood sugar levels through various sweeteners, underscoring the dissatisfaction with their aftertaste and health concerns. Even with technological advancements, sugar substitutes still mimic sugar's flavor and texture, leading to continued disappointment for those seeking a healthier, yet equally satisfying, alternative to sugar. A New Sweetener Has Joined the Ranks of Aspartame and Stevia - The Atlantic

Happiness: Marriage and Money

The Happiness Trinity - The Atlantic delves into the complex question of what truly fuels our happiness. Marriage, according to W. Bradford Wilcox's new book, Get Married: Why Americans Must Defy the Elites, Forge Strong Families, and Save Civilization, emerges as a significant predictor of life satisfaction in America, outshining education, income, and job satisfaction. However, the discourse extends beyond matrimony, exploring "social fitness" — the quality of relationships in one's life — as an even stronger happiness determinant. The article also highlights the intertwined roles of income and social well-being, noting that higher income levels correspond with better marriage and social outcomes. Ultimately, the discussion suggests that happiness in America might morph into a luxury, stratified by income levels, with significant implications for society's overall well-being.

Unraveling the Complexities of Consciousness

The quest to understand consciousness remains elusive, yet tantalizing advances have sparked renewed interest. Grounded in the Orchestrated Objective Reduction (Orch OR) theory, pioneered by Roger Penrose and Stuart Hameroff, researchers posit that consciousness emerges from quantum processes within brain microtubules. Recent explorations extend this theory, demonstrating that microtubules might maintain quantum coherence far longer than expected, suggesting that our brains can sustain these quantum states despite their warm, wet conditions. Complementarily, Timothy Palmer's Invariant Set Theory proposes that consciousness and free will reflect our entanglement in a universal fractal geometry. While far from conclusive, these insights offer intriguing possibilities about the structure and reach of consciousness, bridging scientific inquiry with profound philosophical implications. Where Does Our Consciousness Live? It's Complicated.

071 - Bitter Truths, F-Bombs, and Twinning - HealthHippieMD Week In Review

Twinning to Understand the Impact of Food

New research published in JAMA Network Open involved identical twins on an eight-week dietary trial comparing vegan and omnivorous diets. The vegan group experienced notable health benefits: a 10-15% reduction in LDL cholesterol, 25% lower insulin levels, and a 3% weight loss. This study, unique for using genetically identical twins, highlighted the efficacy of a plant-based diet in improving cardiovascular markers and suggested even partial dietary shifts away from animal products can be beneficial. The findings underscore the potential health advantages of vegan diets while acknowledging the challenges of dietary changes. One identical twin went vegan while the other didn't. See what happened | CNN.

The Rising Tide of Autoimmunity

The article Autoimmunity Has Reached Epidemic Levels. We Need Urgent Action to Address It | Scientific American highlights the alarming increase in autoimmune diseases, now considered an epidemic. It emphasizes the urgent need for action to address this growing health crisis. Autoimmune conditions, where the immune system mistakenly attacks the body, affect an increasing number of people worldwide. The article calls for more research, better public awareness, and improved healthcare strategies to combat these diseases. It underscores the importance of understanding environmental triggers and genetic factors contributing to this surge, advocating for a comprehensive approach to tackle the autoimmune epidemic

A Bitter Truth

"Artificial sweeteners were originally intended to stave off the increasing obesity and metabolic disease epidemic, but instead, they may have directly contributed to it." Artificial Sweeteners May Have Despicable Impacts on Gut Microbes - Scientific American Blog Network delves into the potentially harmful effects of artificial sweeteners on gut microbes. It highlights a study suggesting that these sugar substitutes can inhibit the growth of certain beneficial gut bacteria. This disruption may lead to negative health consequences, as a healthy gut microbiome is crucial for overall well-being. The article underscores the importance of further research to fully understand the impact of artificial sweeteners on our gut health and the broader implications for our diet and lifestyle choices.

AI Travel Tips

Who has "packing a suitcase" on their valuable applications of AI Bingo Card? I certainly didn't. AI Teaches Robots the Best Way to Pack a Car, a Suitcase--Or a Rocket to Mars | Scientific American.

What Ails the NHS

Many people (including me) believe a single-payer system is the only way out of the United State's current healthcare morass. Detractors often point to the issues facing Britain's National Health Service (NHS). The New York Times had an interesting opinion on the origins of the current problems with the British System. As with everything in healthcare, the issue is far more complicated than it first appears: Opinion | Britain Ruined One of the Best Healthcare Systems in the World - The New York Times (gift article).

CVS's New Prescription for Pricing

CVS Health has announced a significant shift in pricing prescription drugs, aiming to simplify and make a traditionally complex system more transparent. Set to launch on January 1, 2025, for commercial payers, the new model, named CVS CostVantage, will calculate drug prices and pharmacy reimbursements using a precise formula. This formula includes the cost of the drug, a defined markup, and a dispensing fee. While this change may not uniformly reduce the cost of all medications, it is expected to generally lower prescription costs for consumers, employers, and health insurers. This initiative follows years of criticism over the U.S. healthcare system's lack of clarity and inflated prices. CVS's move mirrors a similar approach by Mark Cuban's online pharmacy, Cost Plus Drugs, which also aims to reduce medicine prices by selling them at a set markup over cost, plus pharmacy fees. Count me as skeptical that the change will benefit consumers. CVS Says It Will Change the Way Its Pharmacies Are Paid - The New York Times (gift article).

Scientific Grounds

A recent study has brewed up a simple yet effective solution to the messy business of coffee grinding. The research, focusing on the role of moisture in reducing static electricity in coffee grounds, found that a spritz of water on beans before grinding can significantly reduce static. This makes for a tidier grinding process and results in a more consistent and stronger-tasting espresso shot. The study, published in the journal Matter, is a part of the growing field of coffee science, which combines diverse disciplines to enhance our understanding of coffee preparation. Interestingly, the collaboration began through a shared interest in electric charge buildup, a common thread between coffee grinding and volcanic eruptions. This interdisciplinary approach led to the discovery that moisture levels in coffee beans play a crucial role in how they accumulate electric charge during grinding, with lighter roasts gaining less static due to higher internal moisture. The practical takeaway from this study is clear: a little water can go a long way in improving both the cleanliness of coffee grinding and the quality of the brew. There's a better way to grind the coffee, according to science - The Washington Post (gift article).

F-Bombs

Expletive use is on the rise. I present to you A very short history of the F-word - Big Think.

Present Tense

"Traumatic memories are not experienced as memories as such," but as "fragments of prior events, subjugating the present moment." A recent study in Nature Neuroscience delves into the unique neural mechanisms of traumatic memories, which may illuminate why they are so vivid and intrusive. Researchers at Yale University and the Icahn School of Medicine at Mount Sinai conducted brain scans on 28 individuals with PTSD, analyzing their responses to recorded narrations of their memories, ranging from neutral to traumatic. The study revealed that traumatic memories engage the posterior cingulate cortex, a brain area typically involved in introspection or daydreaming. This groundbreaking research offers new insights into the workings of PTSD, suggesting that traumatic memories are processed as ongoing experiences, thereby explaining their persistent and disruptive nature in everyday life. Brain Study Suggests Traumatic Memories Are Processed as Present Experience - The New York Times (gift article).

Harvard's Morgue Mystery

In a shocking scandal at Harvard, the Anatomical Gift Program, where people donate their bodies for scientific study, was exploited for a macabre trade. Cedric Lodge, the morgue manager, along with several others, was indicted for stealing body parts and selling them to oddity collectors. Families who had donated their loved one's body were horrified to discover that the remains might have been part of this gruesome trade. This betrayal of trust at such a prestigious institution has left many in disbelief and mourning, questioning the integrity of body donation programs and the dark underbelly of oddity collecting. Inside The Harvard Morgue Scandal: Missing Body Parts, Mourning Families.

048 - Mindfulishness, Alzheimer's and the Microbiome, VR Forest Bathing - HealthHippieMD Week In Revie

Alzheimer's and the Microbiome

In a groundbreaking study, researchers have discovered that alterations in the human gut microbiome can precede the cognitive declines associated with Alzheimer's disease. The study, led by experts in the gut microbiome and Alzheimer's research, found distinct differences in the gut bacteria of individuals in the preclinical stages of Alzheimer's, even before any visible symptoms emerge. The findings raise the possibility of using stool sample analysis to detect early risk for Alzheimer's, enabling earlier interventions to slow or halt its progression. Further research aims to determine if targeted dietary changes or probiotic treatments can effectively modify the gut microbiome and delay Alzheimer's development. Changes in Human Microbiome Precede Alzheimer's Cognitive Declines

Mindfulishness: Are Meditation Apps a Distraction Trap?

In the thought-provoking article, Your Phone Is the Wrong Place to Go for Mindfulness, the author explores the paradoxical nature of meditation apps and their relationship with smartphones. While mindfulness apps offer convenient access to meditation practices and promise to bring peace of mind, they also contribute to the ever-present distraction of smartphones. The article questions the effectiveness of using these apps on a device that is notorious for causing unfocus and stress. It highlights the need for mindful choices in our phone usage and suggests that true mindfulness may lie in disconnecting from the screen altogether.

When is Anxiety a Problem?

Anxiety disorders affect approximately 1 in 5 American adults. Understanding when anxiety becomes problematic is crucial. While anxiety can serve as a protective alarm system, persistent worry and interference with daily life may signal the need for evaluation and treatment. Dr. Petros Levounis, President of the American Psychiatric Association, sheds light on recognizing anxiety's red flags and the available treatments. Notably, the article also addresses the omission of older adults from the screening recommendations and emphasizes the importance of discussing emotional concerns with healthcare providers. When Is Anxiety a Health Problem? What to Know About New Screening Guidelines - The New York Times (gift article)

Unraveling Statins

Researchers have uncovered the long-standing puzzle surrounding the muscle-related side effects of statins, America's most popular drug for managing cholesterol. While investigating the genetic causes of limb-girdle muscle dystrophy, two independent groups of scientists unexpectedly identified mutations in the gene encoding the HMG-CoA reductase enzyme—the same enzyme statins inhibit to reduce cholesterol production. The discovery sheds light on the connection between a rare genetic disease and statins' common muscle-related side effects, offering potential insights for targeted treatments and improving the lives of severely affected patients. The Gene That Explains Statins' Most Puzzling Side Effect - The Atlantic

Forest Bathing in VR

Scientists are studying whether computer-generated forests have the same effect on health and well-being that natural forests do. "Forest bathing" might work in virtual reality too | MIT Technology Review

Dark Side of the Rainbow

In Pink Floyd, 'The Wizard of Oz' and Me, (gift article) a journalist shares his connection to the phenomenon that occurs when Pink Floyd's album "The Dark Side of the Moon" is played in sync with the movie "The Wizard of Oz." The article delves into the strange and surreal coincidences that arise from this synchronization and explores the journalist's role in popularizing the concept through his early internet presence. The story reflects on the cultural impact of this unique pairing and the enduring intrigue it continues to evoke.

Virtual Tours of the NIH

Are you curious about the history and footprint of the National Institutes of Health? You can now take a virtual tour: Virtual Tour | National Institutes of Health (NIH)

Canine Clinical Trials

Dog cancer research is helping drug development for humans and canines (gift article) is about driving advancements in the development of cancer drugs for both humans and canines. Comparative oncology, the study of cancers in companion animals, offers insights into human treatments and has gained momentum due to the high failure rate of cancer clinical trials using mouse models. Studying dogs provides advantages such as shared environmental factors, cleaner data, and easier data sharing, leading to potential breakthroughs in cancer treatment for both species.

The Brain as a Prediction Engine

"For as long as we've studied human cognition, we've believed that our senses give us direct access to the world. We see what's there—or so the thinking goes. But discoveries in neuroscience and psychology have turned this assumption on its head. What if rather than perceiving reality passively, your mind actively predicts it?" I just bought the book The Experience Machine: How Our Minds Predict and Shape Reality.

Trauma Hijacks the Prediction Algorithms of the Brain

The neuroscience of trauma is an interesting video featuring Dr. Lisa Feldman Barrett, who contends that trauma alters the prediction algorithms of the brain.

Anti-Prosopagnosiacs: Human Super-Recognizers Outshine AI in Facial Recognition

Current facial recognition technology has error rates ranging from 48 to 62 percent. To address this issue, police forces in London, Berlin, and Queensland have enlisted super-recognizers help—individuals with an innate talent for recognizing unfamiliar faces. Studies show that these human experts excel in challenging scenarios where AI falls short, such as low-resolution images or crowded environments. However, racial bias remains a challenge even for super-recognizers. Researchers aim to identify exceptional talents and uncover the secrets behind their extraordinary face recognition abilities. Police Are Using Human Super-Recognizers to Replace Facial Recognition Algorithms in Some Contexts.

End the Tyranny of Processed Food

"Anyone who's struggling with [food-related disease] as an individual should take their guilt and shame and transfer it outwardly to the corporations that are feeding us these addictive substances, to the governments doing nothing about it, and to the physicians and the social media personalities who keep telling us that this stuff is healthy. We must end the conflict of interest between the industry, politicians, doctors, and scientists. Only then can we tackle the problem." An opinion piece about the role of processed food in today's society. I agree with most, except for the part about physicians conspiring. The actual problem with physicians is a lack of understanding. It's Time to End the Tyranny of Ultra-Processed Food

Aspartame to be Declared Carcinogenic by WHO

The World Health Organization will reportedly categorize Aspartame/Nutrasweet as potentially carcinogenic. Aspartame: Key ingredient in Diet Coke set to be declared 'possible cancer risk' by WHO I also learned of a study last year (in mice) where aspartame increased anxiety and fear processing across generations.Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala

045 - Dying Brains, Frenemies, and the Physiology of Hangry - HealthHippieMD Week In Review

Flavanols Combat Memory Loss in Aging Adults

A new study reveals that flavanols, nutrients found in select fruits and vegetables, are crucial in mitigating age-related memory decline. The research demonstrates a positive correlation between flavanol intake and memory test scores among older adults. Notably, individuals over 60 with low-flavanol diets experienced significant memory improvement after reintroducing these dietary components. This study supports the emerging understanding that specific nutrients are essential for maintaining optimal brain health as we age. By highlighting the power of flavanols, the research offers potential avenues for improving cognitive function in older adults and underscores the importance of a flavanol-rich diet or supplements. Memory Boosting Power of Flavanols in Aging Adults

Gut Check

Scientists have discovered the mechanism behind how chronic stress can lead to gut inflammation. Signals originating in the brain reach gut nerve cells, triggering the release of inflammatory chemicals. The study, The enteric nervous system relays psychological stress to intestinal inflammation glucocorticoids act on gut neurons and glial cells, which then activate immune cells. These immune cells release molecules that cause painful bowel inflammation. The findings suggest that managing stress levels could significantly impact the effectiveness of treatments for inflammatory bowel disease (IBD). The research opens possibilities for targeting the brain-to-gut signaling pathway for new therapies. Chronic stress can inflame the gut — now scientists know why

Frenemies Take a Toll

According to psychologists, ambivalent relationships, known as frenemies, which combine positive and negative aspects, can be more detrimental to health than purely negative relationships. Research reveals that interacting with individuals who evoke mixed feelings can raise blood pressure and lead to negative physical symptoms. Even a single ambivalent interaction can have adverse effects on well-being. Unpredictability increases pain from unpleasant interactions, and rumination contributes to the negative impact of such relationships. Recognizing the harmful effects of frenemies is important for maintaining overall health and well-being. Opinion | Ambivalent Relationships May Be Hazardous to Your Health. (gift article)

The Neuroscience of Hangry

Neuroscientists have discovered a cluster of cells called AgRP neurons that stimulate appetite and play a vital role in the infamous "hangry" feeling. These cells near the brain's blood supply receive signals from the stomach and fat tissue, influencing our hunger levels. By manipulating AgRP neuron activity in mice, researchers have identified how they trigger food-seeking behavior and respond to the presence of nutrients. This breakthrough could lead to new therapies for eating disorders like anorexia and overeating. By understanding and controlling the hangry feeling, scientists hope to revolutionize our ability to manage our diets effectively. Neuroscientists May Have Found the Part of Your Brain That Makes You Hangry

Electrical Activity Surges in the Dying Brain

A new study reveals that dying brains experience a surge of electrical activity, challenging the assumption that brain activity decreases during dying. Researchers monitored four comatose patients who died in a neurointensive care unit and observed a surge of neurophysiological activity in regions associated with conscious processing. This surge included increased synchronization and connectivity between different brain regions. While the study doesn't directly explain near-death experiences, it suggests that the observed brain activity pattern may contribute to the vivid perceptions reported during such experiences, prompting further investigation into the nature of human consciousness. Scientists monitored four dying patients' brains. Here's what they saw . In the late 2000s, David Auyong and I observed the same phenomenon while on call: Processed electroencephalogram during donation after cardiac death.

Biochemistry of Psychedelics, BDNF, and Neuroplasticity

Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience reveals that LSD and magic mushrooms dramatically rewire the brain, offering new possibilities for treating depression. The research conducted by an international team of scientists from the University of Helsinki shows that, at least in a test tube, these psychedelics bind to a protein called receptor tyrosine kinase beta (TrkB), which activates brain-derived neurotrophic factor (BDNF). BDNF plays a crucial role in neuron growth and development. This discovery paved the way for developing safer and more effective treatments for mental health disorders. LSD and Magic Mushrooms Dramatically Rewire the Brain, New Study Reveals.

AIHits (Generative AI Music and Podcasts)

"What makes pop work is that it's always changing and always responding. This is just a feedback loop between systems." AI is having a profound effect on artistic expression in music. Now there's a website to listen to. AI Could Usher in a New Era of Music. Will It Suck?

+The Generative AI gold rush is on in the podcasting space, too, as if the genre wasn't already overcrowded: Generative AI Podcasts Are Here. Prepare to Be Bored.

The Evolutionary Significance of Dreaming

"REM [sleep] has been crucial to human creativity."The evolutionary significance of dreaming is an interesting video on BigThink.

External Stressors Affect Cancer Mortality

Surprise, surprise! Higher allostatic load, a quantitive measure of the cumulative physiological damage from stress, is associated with worse cancer outcomes: Evidence Emerges Showing External Stressors Adversely Affect Cancer Outcomes

Sucralose-Genotoxic?

At least in test tubes, new evidence shows that Sucralose (Splenda) can disrupt DNA. "It's time to revisit the safety and regulatory status of sucralose because the evidence is mounting that it carries significant risks." Sucralose Damages DNA, Linked to Leaky Gut: Study (thanks, Diana!)

042 - Quantum Biology, Wearables, and Birdsong - HealthHippieMD Week In Review

Quantum Biology

This scientist believes nature has harnessed "quantumness" and that our current beliefs about biology are sorely incomplete: Quantum physics proposes a new way to study biology – and the results could revolutionize our understanding of how life works.

Pushing Our Kids to Achieve

Do we do our kids a disservice by pushing them to achieve? This author thinks so: Opinion | What We Lose When We Push Our Kids to 'Achieve' - The New York Times (gift article)

The Newest College Admission Scam: Publish a "Scholarly" Paper

An emerging industry of research services is helping high school students produce and publish research papers to boost their college applications. Online programs, such as Scholar Launch, charge thousands of dollars to connect students with mentors who guide them in writing articles, which are then published in journals of questionable quality. The Newest Way to Buy an Advantage in College Admissions.

Resisting Alzheimer's

Patients whose health doesn't conform to expectations can offer new insight into a possible disease treatment. Such is the case with a man who, based on his D.N.A., "should of" developed Alzheimer's in his 40s but showed resilience to the disease. Mutation Protected Man From Alzheimer's Disease, Hinting at Treatment. (gift article)

WHO Says "No" to Non-Nutritive Sweeteners

The World Health Organization (W.H.O.) has cautioned against using artificial sweeteners for weight control and reducing the risk of noncommunicable diseases. The W.H.O. stated that these alternatives to sugar do not effectively reduce body fat in adults or children and could potentially increase the risk of Type 2 diabetes, cardiovascular diseases, and mortality. This recommendation contradicts previous studies that suggested no harm from sweeteners. Based on a comprehensive review, the W.H.O.'s advice emphasizes the importance of reducing overall sugar intake and relying on naturally occurring sugars found in fruits and unsweetened foods and beverages. World Health Organization Warns Against Using Artificial Sweeteners (gift article)

Therapy Unpacked

Therapy once stigmatized as a luxury for the neurotic, has gained acceptance and popularity over the years. This article explores the effectiveness of talk therapy in improving mental health. While studies suggest that therapy indeed works and yields positive results, there are ongoing debates and challenges in the field. Researchers are trying to determine the best types of therapy for different individuals and understand the impact of the therapist-patient relationship. Some argue for a shift toward more innovative strategies, while others believe therapy's potential hasn't been fully unlocked. Ultimately, the therapist's skills and the bond formed with the patient are crucial to therapy's success. Does Therapy Work? Let’s Unpack That. (gift article)

New Manuscript Defines Frequency of Chronic Pain

"New cases of chronic pain occur more often among U.S. adults than new cases of several other common conditions, including diabetes, depression, and high blood pressure." A new analysis points to the high disease burden of chronic pain in the U.S. U.S. National Survey Data Show High Rates of New Cases and Persistence of Chronic Pain.

The Slumbering Successes of Innovation in Nature and Culture

In his book "Sleeping Beauties: The Mystery of Dormant Innovations in Nature and Culture,", biologist Andreas Wagner discusses how many brilliant ideas and innovations fail immediately but instead emerge and persist in the shadows until the right time arrives for them to step into the limelight. Wagner argues that the success of an innovative product, whether it's a new form of life or a work of art, depends not only on its inner qualities but also on the right environment and timing. He emphasizes the importance of understanding delayed success and empathizing with oneself in the creative process. Why Many Brilliant Ideas Don't Succeed Immediately.

Patients Hack Wearables to Monitor Chronic Illness

"What we have right now is a health and wellness industry that provides data-driven insights and data-driven advice, so long as their physiology is typical." How Chronic Illness Patients Are 'Hacking' Their Wearables describes how patients are using consumer electronics, such as the Oura Ring, Fitbit, and Apple Watch to monitor less common chronic illnesses.

Burned-Out on Burnout

How to address physician burnout. discusses the issue of physician burnout and challenges the prevailing approach to addressing it by embracing the humanities. I think the article misses the point or at least gives only a partial solution. Rather than implying burnout is a personal failing, it should be considered a healthcare system failure. One of my favorite papers on this subject was written by Tait Shanafelt before the pandemic: Executive Leadership and Physician Well-being: Nine Organizational Strategies to Promote Engagement and Reduce Burnout.

Birdsong and Mental Health

Research has consistently demonstrated that more contact and interaction with nature improves physical and mental well-being. Scientists are examining whether birdsong contributes to nature's positive effects: Why birds and their songs are good for our mental health. (gift article)

Banning Food Dyes

"They have no known nutritional benefits and potentially carry several health risks." The Atlantic had a story on efforts around the world to ban artificial food coloring: The True Danger of Food Dye.

032 - Bayesian Thinking, Cadavers, and Medical Unions - HealthHippieMD Week In Review

House Staff Local 131

I read an article about physicians unionizing. Although there has been talk about this for quite some time, I did not realize it had already happened in several locations: Doctor Unions Are Good for Your Health

Avatar Now

What do you get when you combine the immersive collaborative experience of an escape room with a video game? You get a Gamebox. Immersive Video Games Are Coming to a Theater Near You

The Plant Whisperer

Are plants sentient? I'm still not convinced, but this scientist theorizes they might be. What Plants Are Saying About Us - Nautilus

Spring Ahead

I read an article from a sleep scientist about the downsides of Daylight Savings time. The report convinces us that we should be on a permanent Standard Daylight schedule, not a permanent Daylight Savings schedule, as is currently suggested in a Congressional Bill.Springing forward into daylight saving time is a step back for health – a neurologist explains the medical evidence and why this shift is worse than the fall time change

Swiss Miss

The iconic Matterhorn of the Swiss Alps will no longer be seen on the wrappers of Toblerone chocolate bars after production moves from Switzerland to Slovakia. Where are Toblerone chocolate bars made?

Taking Control of What you Read on the Internet

Here is an article on the 25-year-old technology, RSS feeds: It's time to take back control of what we read online. I use RSS feeds in various ways. For my daily news, I rely on Feed Bin and Unread. I previously wrote about the ways I use RSS in scholarly activities: Unlock the Power of RSS feeds with DEVONthink — Workflows in Personal and Professional Productivity

This is your Brain on Art

"Art is not a luxury for our downtime, but an important contributor to physical and mental well-being..." I couldn't agree more, especially regarding music. How art, music, and dance affect your brain and body. (gift article)

Non-Nutritive Sweeteners

Artificial sweeteners are in various foods, from bread and cereal to tortillas and greek yogurt. Here is an article on the dark side of sugar substitutes: How sugar substitutes sneak into foods and affect your health (gift article)

Healthy, Redefined

The FDA is cracking down on commercial foods that may be labeled 'healthy.' The food companies are resisting: FDA is redefining 'healthy,' and the food industry is pushing back (gift article)

Personality Testing in the Workplace

Many years ago, I went down the rabbit hole, taking any personality test I could get. Although many personality tests (i.e., MBTI) have not been validated, they are increasingly used to make workplace decisions. Personality testing is now a $2 billion industry. The $2 Billion Question of Who You Are at Work (gift article)

The Argument for Moving Closer to Your Friends

"Many people are prepared to move for a new job, to be with a romantic partner, or even just for an adventure. Moving to be closer to buddies should be no different. Friends are not incidental to a good life; they're essential to one. So why not shorten the distance between you and them?" Live Closer to Your Friends

Health Podcasts Worth Listening To

....at least according to the NY Times. I am going to check out a few of these: Here Are 12 Health Podcasts Worth Listening To (gift article)

What Fuels Teen Anxiety?

Reformers have argued for fewer hours in a workweek. Yet, simultaneously, demands on our children at school have increased. Many believe the time needed to become attractive college applicants at the root of teen anxiety: "Richer and more complex economies require more rigorous and intense education, putting more pressure on kids to be high-achieving perfectionists." We're Missing a Key Driver of Teen Anxiety

Does your Microbiome Influence Interest in Exercise? (pre-clinical)

An interesting article in WaPo about how, in mice, the microbiome influences interest in exercise: How your microbiome may influence your motivation to exercise - The Washington Post (gift article)

Cannabis and Anesthesia

An article in the Economist discusses how cannabis influences the amount of drugs needed for adequate anesthesia. Cannabis and anesthesia do not mix

A Short History of Medical Cadavers

Medical students traditionally dissect cadavers while learning anatomy. Ever wonder where the bodies come from? From grave robbing to giving your own body to science – a short history of where medical schools get cadavers "Where many Americans once regarded medical students as "butchers" for exploiting their beloved dead, contemporary students honor what some of these future doctors call their "first patients" for the precious gift they have been given."

Bayes' Rule

After seeing all the evidence, how strongly should you believe something? That question is at the heart of Bayesian thinking, named after the Reverend Thomas Bayes. Here is an interesting video explaining Bayes Rule: Harvard professor explains Bayes' rule and an interesting article on how to use Bayesian Thinking to influence our relationships: Bayes and Deadweight: Using Statistics to Eject the Deadweight From Your Life.