Pessimism

084 - Digital Doppelgangers, Whispers in White Noise, and Optimism in Longevity - HealthHippieMD Week In Review

Digital Doppelgangers: Revolutionizing Diabetes Management

Twin Health has innovated a groundbreaking approach to managing type 2 diabetes by creating digital twins of the human body. These virtual avatars are built using multiple data points from sensors and AI algorithms to generate a personalized model of a patient's metabolism. The digital twin continuously learns from real-time data, offering tailored predictions and recommendations for managing blood sugar levels. In a clinical trial, patients using this technology saw significant reductions in blood sugar levels, with nearly 73% achieving remission after a year. The future of this technology promises a personalized and proactive approach to managing chronic diseases like diabetes, potentially transforming global healthcare standards. Interestingly, in 2014, I wrote a proposal for NLM and then NIDDK for this exact purpose. My proposal went unfunded, but seeing I was on the right track is rewarding. Digital twins are an effective new way to control your metabolism.

Sitting on a Time Bomb

A recent study by the University of California, San Diego (UCSD) has unveiled alarming findings about the health risks associated with prolonged sitting. Tracking 5,856 women aged 63 to 99 over a decade, researchers discovered that those sitting for more than 11 hours daily had a 57% higher risk of death compared to those sitting for less than 9.5 hours. Contrary to popular belief, even regular moderate-to-vigorous exercise couldn't offset the dangers of excessive sitting. However, an Australian study suggests that walking 9,000 to 10,500 steps daily could reduce the risk of premature death, even for habitual sitters. The discrepancies between studies might be due to different methods of measuring sitting time. The UCSD study's robust evidence underscores the importance of minimizing sitting time and breaking it up with periods of standing or walking, which aligns with World Health Organization guidelines. Sitting Is Even Deadlier Than We Thought, A New Study Reveals.

The Concussion Conundrum

The article explores the misconceptions surrounding concussion treatment, highlighting the story of Conor Gormally, who suffered multiple concussions. For years, the medical advice for concussion recovery emphasized total rest, but emerging research indicates that active rehabilitation, involving activities like exercise, reading, and screen time, is more effective. Despite this shift in understanding, many patients still receive outdated advice to "cocoon" themselves in rest, delaying their recovery. The article calls for a change in how concussions are treated, emphasizing the need for updated medical education and patient-centered care. Concussion: there's an insidious myth about a common sports injury. Even doctors believe it.

Optimism's Role in Longevity

The New Science of Optimism and Longevity explores the biological significance of optimism in promoting healthy aging and reducing disease risk. People with optimistic mindsets exhibit better cardiovascular, pulmonary, metabolic, and immunological health, leading to lower incidence of age-related illnesses and reduced mortality. A 2019 review found that optimists have a 35% lower risk of cardiovascular events and tend to live 11-15% longer than pessimists. The article also discusses the potential of optimism in slowing down cellular aging, as evidenced by studies on telomere shortening. While genetics play a role, optimism can be cultivated through social relationships and positive thinking practices, offering a strategy for enhancing physical and mental well-being.

Whispers in the White Noise

Have you ever heard mysterious voices or music in your white noise machine? You're not alone. This phenomenon, known as auditory pareidolia, occurs when your brain tries to match patterns in continuous noise, like white noise, with familiar sounds. It's a normal brain function, not a sign of schizophrenia or other psychological disorders. Experts explain that our brains are pattern-matching machines, constantly searching for recognizable sounds in the noise we hear. While it might be unsettling to listen to these phantom sounds, there's no need for concern unless you hear them without any noise present. If you're bothered by these sounds, try switching to a different type of noise or moving away from the source. Why You Hear Voices in Your White Noise Machine | WIRED.

The Impact of Electronic Music on Consciousness

Electronic music isn't just for dancing; it can also significantly alter our consciousness. Research shows that electronic music's repetitive beats and rhythms can induce trance-like states, impacting brainwave patterns and emotions. This effect is not only utilized by club-goers but also by therapists for meditation and relaxation. The article explores how electronic music's unique characteristics can influence our mental and emotional well-being, offering a new perspective on the power of music in shaping our state of mind. Brain beats: How electronic music can alter our state of consciousness. +see also Electronic music appears to alter our state of consciousness | New Scientist (subscription required)

Disconnect to Reconnect

Finding a healthy relationship with our devices is crucial in an age where technology is omnipresent. 5 Tips for a Healthier Relationship With Your Phone - The New York Times (gift article) offers practical advice for managing screen time without completely unplugging. Key suggestions include being mindful of automatic urges to check devices, limiting phone use while on the move, scheduling short tech breaks, creating an environment that encourages less phone usage, and ensuring that technology serves you, not the other way around. These tips help individuals regain control over their digital lives and foster a more balanced interaction with their gadgets.

Cool Your Jets

A comprehensive review of 154 studies by Sophie L. Kjaervik and Brad Bushman has revealed that traditional methods of managing anger, such as hitting a punching bag or jogging, may be ineffective. Instead, activities that decrease physiological arousal, like deep breathing, muscle relaxation, yoga, meditation, and mindfulness, have significantly reduced anger and aggression across various settings and populations. The research challenges the notion that venting anger is beneficial, highlighting that simple and accessible techniques can be more effective for anger management. This study offers evidence-based strategies for better anger control, promoting healthier outcomes and societal well-being. Chilling out rather than blowing off steam is a better way to manage anger − new review of 154 studies reveals what works.

030 - Hard Dew, Endocannabinoids, and Thinking Like a Monk - HealthHippieMD Week In Review

ChatGPT Writes Obituaries Too

This author experimented with ChatGPT, having it write her eulogy: I Had An AI Chatbot Write My Eulogy. It Was Very Weird Although I found the concept of the article interesting, the author lost me with the last paragraph, "Regardless of how advanced these tools become, one thing should now be obvious: their well-documented biases and flawed decision-making abilities mean they should never be used to do anything of consequence." Totally disagree!

ChatGPT and Science

Are you using generative AI to generate research ideas and scholarly publications? It's already possible: "...a chatbot was deemed capable of generating quality academic research ideas." Why ChatGPT Could Usher in a New Era of Scientific Discovery

Tim Urban Writes a Book

I'm rarely excited by an upcoming book. But Tim Urban, the creative force behind Wait But Why (one of my favorite websites), is publishing a book this week (Amazon | Apple). In his latest blog post, A Short History of My Last Six Years — Wait But Why, he explains the six-year journey examining our society. "This book is my best crack at explaining what I think is an existential risk to liberal societies and what I think we need to do to get to that awesome future I used to be so excited about."

ME/CFS and the Microbiome

I've written about how Long Covid has ignited interest in a long-time ignored and misunderstood medical condition, ME/CFS. The NIH Director's blog mentioned recent clues to the disease in the microbiome: "... suggesting that imbalances in certain bacterial species inhabiting the gut could be used as measurable biomarkers to aid in the accurate and timely diagnosis of ME/CFS. It also points to a possible therapeutic target to explore."_ More Clues into ME/CFS Discovered in Gut Microbiome – NIH Director's Blog

Vibrating Pills for Constipation

Here is a new, FDA-approved medical device for the drug-free treatment of constipation: Vibrating Pill for Constipation Now Available This adds a whole new meaning to moving your bowels.....

You are not Your Attachment Style

I love the book Attached.. Here is an interesting article that offers an overview of Attachment Theory and some of the more common misperceptions: You Can Change Your Attachment Style

Friendship

The Atlantic curated a series of articles on enduring friendship: Why We Lose Our Friends as We Age - The Atlantic (subscription required)

Relationships and Serious Disease

Being diagnosed with a severe illness is challenging enough. But medical issues also can have a devastating effect on relationships/marriages: Why Men Leave Sick Wives - Facing Illness Alone

Optimism and Pessimism

"_Optimism and pessimism, it turns out, are all about the stories we tell ourselves after both our successes and our failures._" Are You (Still) an Optimist? These Questions Might Help Explain Why (gift article)

Six Steps to Improve Your Mood for Good

An academic happiness researcher advises on improving your life: The Key to Happiness: 6 Strategies To Boost Your Mood for Good

Asthma Drug Recovers "Lost" Memories (Pre-Clinical)

A side effect of sleep deprivation is amnesia, but whether memory loss is a storage or retrieval problem has been unclear. These scientists are zeroing in on the answer: "This study shows that neurons in the hippocampus retain the memories, albeit in an inaccessible state, but that they can be rescued artificially." Asthma drug brings back "lost" memories

Ultra-processed Foods and Obesity

Wired had a great overview of the impact of ultra-processed foods on body weight. "The results of the study surprised Hall. On the ultra-processed diet, people ate around 500 extra calories daily and weighed about two pounds more pounds." Fat, Sugar, Salt ... You’ve Been Thinking About Food All Wrong

Endocannabinoids and Health

Just like opiates, your body produces endogenous compounds that bind to the same receptors as compounds in marijuana. Research on endocannabinoids lags far behind opiates, but research has shown "An imbalance in the production of endocannabinoids, or in the body's responsiveness to them, can lead to major clinical disorders, including obesity as well as neurodegenerative, cardiovascular and inflammatory diseases." People produce endocannabinoids – similar to compounds found in marijuana – that are critical to many bodily functions is a nice overview. For more on endocannabinoids, see: Why does running give you a high? A look at the science and Cannabinoids - HealthHippieMD

The Brain and the Immune Response

Nature had an excellent overview of efforts to unravel further how the brain affects immune function: Your brain could be controlling how sick you get — and how you recover (subscription required)

The Dark Side of Ketamine Telemedicine

Covid influenced many changes in medicine. One of those changes was a loosening of regulations surrounding the remote prescription of controlled substances. A Fraught New Frontier in Telehealth: Ketamine (gift article) talks about the dark side of the remote prescription trend.

The Book of Blue Zones

The Economist had an interesting article on Blue Zones, an area of the world with a disproportionate share of centenarians: Christian Californians may have a solution to America's obesity | The Economist (subscription required)

Hard Dew

I had no idea about the roots of Mountain Dew. I had no idea Mountain Dew was a nickname for moonshine. Why PepsiCo's and Coca-Cola's Alcohol Drinks Worry Health Experts (gift article) discusses the worrisome trend of "hardening" traditional soft drinks. Next up, marijuana tinged soft-drinks.....

Think Like A Monk

In addition to Tim Urban's book, I've started reading Think Like a Monk by Jay Shetty. I'm about three chapters in and enjoying the material. Highly recommended! (Thanks, Sandy!)