120 - Mirror Cells, Fighting Inflammation with Food, and Artful Healing - HealthHippieMD Week In Review

120 -- HealthHippieMD Week In Review Audio Overview

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Curiosity Killed the Bias

How to see the humanity in anyone | Psyche Guides explores the transformative practice of "deep curiosity," a tool for fostering empathy, connection, and understanding across divides. The author recounts a yearlong journey meeting individuals with opposing beliefs and challenging stereotypes fueled by assumptions and social media. Through the DIVE model—Detach, Intend, Value, Embrace—he teaches how to unlearn biases, prepare for meaningful dialogue, and honor others' dignity. By viewing challenges as opportunities for growth, deep curiosity strengthens relationships and enriches self-awareness. This guide empowers readers to break barriers and connect authentically in an increasingly polarized world. (Thanks, Laura!).

+see also: The War For Kindness - The Happiness Lab with Dr. Laurie Santos - Apple Podcasts.

Food Fights Inflammation

An anti-inflammatory diet swaps processed foods for whole, nutrient-dense options to combat chronic inflammation. Foods rich in antioxidants, polyphenols, and essential nutrients help reduce oxidative stress and regulate hormones. A Mediterranean-inspired diet—packed with fruits, vegetables, fish, nuts, and olive oil—nurtures a healthy gut biome, while magnesium-rich and brightly colored foods fight stress and free radicals. Spices like turmeric and garlic add flavor and anti-inflammatory benefits. While diet is just one piece of the wellness puzzle, adopting these habits offers long-term physical and mental health benefits—making it a marathon worth running. An anti-inflammatory diet can boost your health. What to eat and what to avoid | Fortune Well.

How Seed Oils May Ignite Cancer Risks

A new study highlights the potential role of omega-6 fatty acids—abundant in seed oils used in ultra-processed foods—in promoting inflammation that fuels colon cancer. Researchers found high levels of these proinflammatory lipids in tumor samples, alongside a deficiency in inflammation-resolving omega-3s. Experts point to dietary shifts since the 1950s, with ultra-processed foods and seed oils dominating modern diets, as a likely factor. While diet isn't the sole contributor, the findings emphasize the complex interplay of food, lifestyle, and genetics in cancer risk, advocating for moderation in omega-6 consumption pending further research. Ultraprocessed Foods High in Seed Oils Could Be Fueling Colon Cancer Risk | Scientific American.

Chasing Happiness

What can ancient philosophy teach us about a well lived life? Examining different schools of philosophical thought can teach us a lot about different ways to create happiness. The philosophy of happiness, explained in 10 minutes - Big Think.

Love Is a Marathon, Not a Sprint

Arthur C. Brooks explores the paradox of love and happiness, arguing that the exhilarating, passionate phase of romance—while thrilling—isn't what brings enduring joy. Instead, he highlights "companionate love," rooted in friendship, mutual understanding, and commitment, as the foundation of lasting happiness. Backed by research like the Harvard Study of Adult Development, Brooks demonstrates that stable relationships, especially those built on deep friendship, are the strongest predictors of lifelong contentment. With humor and personal anecdotes, he underscores that the secret to staying in love lies in simply liking your partner—your best friend. The Kind of Love That Makes People Happiest - The Atlantic.

+see also: This heartwarming video from Coldplay featuring Dick Van Dyke. All My Love Official Version, Director's Cut.

Press Paws

A recent study suggests that dogs may communicate intentionally by pressing buttons linked to words. Researchers found that some dogs form two- or three-word combinations, such as "want food," which appear deliberate rather than random. The study monitored button-pressing behaviors in over 150 dogs using soundboards, finding that dogs can express needs akin to a young child. However, skeptics argue the behavior could stem from training or reinforcement rather than true language understanding. While questions remain, the research highlights dogs' intelligence and their potential for deeper interaction with humans. Dogs may be able to communicate by pressing buttons, research suggests - The Washington Post (gift article).

Snooze You Can Use

Science-Backed Sleep Tips from 2024 to Help You Snooze Better | Scientific American explores 2024's popular sleep trends and their scientific validity. Highlights include the benefits of short naps for memory and mood and caution against "bed rotting," which disrupts circadian rhythms. TikTok's "sleepy girl mocktail" sheds light on magnesium's role in relaxation, while sleeping on the floor offers mixed results for back health. Sleep divorces—partners sleeping separately—can improve rest for mismatched sleepers. To combat election-induced insomnia, experts recommend unplugging, meditating, and reframing anxious thoughts with gratitude. These evidence-backed strategies aim to optimize sleep quality for a more restful 2025.

Artful Healing

Susan Magsamen's exploration of neuroaesthetics reveals the profound effects of art on mental health, trauma recovery, and cognitive disorders. This emerging field connects art, science, and well-being, showing how aesthetic experiences—from painting and dance to music—positively reshape our brains. Programs like Creative Forces empower trauma survivors, while dance improves cognition and mobility in Parkinson's patients. The arts, accessible to all, offer transformative benefits, reducing stress and fostering resilience. By embracing creativity, we can enhance our mental and physical health, proving that the arts are as essential as exercise or nutrition. 'Neuroaesthetics' Reveals How the Arts Help with Dementia and Trauma | Scientific American.

Neuroinflammation and Muscle Fatigue

Neuroinflammation, sparked by the brain's immune response to infections or chronic diseases like Long COVID and Alzheimer's, disrupts the brain-muscle connection, leading to muscle fatigue. This research uncovers how brain-released cytokines alter muscle energy production without damaging muscle structure. Studying fruit flies and mice, scientists identify a universal brain-to-muscle communication pathway that reallocates energy to combat infection. Potential treatments, such as neutralizing antibodies, aim to block this signaling. With further exploration, targeting this axis could alleviate fatigue in long COVID and other neuroinflammatory conditions, improving life for millions worldwide. Brain inflammation may be the reason behind muscle fatigue after infection and injury.

Mirror Cells: The Dark Reflection of Life

Scientists warn of the existential risks posed by "mirror cells," organisms built with reverse-handed DNA and proteins, defying the fundamental biology of Earth's life forms. These synthetic microbes, immune to natural defenses and capable of ecological devastation, could trigger pandemics or disrupt ecosystems if released. While promising medical advancements like long-acting drugs, their potential to bypass immune systems and evolve uncontrollably outweighs the benefits. Leading researchers advocate banning this technology, urging global dialogue to prevent catastrophic consequences before these innovations take root. A 'Second Tree of Life' Could Wreak Havoc, Scientists Warn - The New York Times (gift article).

+see also: one of the most memorable articles from Wired (from 25 years ago!)-Why the Future Doesn't Need Us | WIRED.

The Gut: The New Frontier of Mental Health Treatment

Emerging research highlights the potential of targeting gut cells, rather than brain cells, to treat depression and anxiety. Traditional SSRIs, while effective, often cause systemic side effects. Scientists have observed mood improvements in mice without the usual drawbacks by focusing on serotonin production in the intestines, unveiling the gut-brain connection's crucial role in emotional regulation. This novel approach may also address concerns about SSRI safety during pregnancy, offering a safer alternative for both mothers and babies. These findings could revolutionize mental health care by delivering effective relief without compromising physical well-being. Drugs targeting gut cells, not brain cells, fight depression better - Earth.com. (thanks, Amy!).

+see also: Gut Feelings: The Role of the Microbiome in Behavioral Health — HealthHippieMD.

115 - Doppelgangers, Ghosting, and Ephaptic Fields - HealthHippieMD Week In Review

Turning Disappointment into Resilience

In How to Deal With Disappointment - The Atlantic, Arthur C. Brooks explores the universal experience of disappointment, often arising when our expectations clash with reality. He differentiates disappointment from regret, emphasizing its link to feelings of powerlessness rather than self-reproach. Optimists are particularly vulnerable, as their positive outlooks set them up for deeper emotional dips when outcomes don’t meet their hopes. Brooks advocates for hope over blind optimism, suggesting that resilience and proactive strategies can soften the blow of letdowns. Individuals can foster a more balanced, growth-oriented perspective by learning from disappointment.

Sorting Stomach Signals

This comprehensive article dives deep into common concerns about gut health, exploring the essential role of the microbiome and addressing 15 frequently asked questions. Key signs of a healthy gut include quiet digestion and regular bowel movements, while persistent issues like bloating, acid reflux, or irregularity may indicate trouble. Experts suggest fiber-rich, plant-based diets, limited processed foods, and occasional fermented items to boost gut health. Topics also cover heartburn, the effects of antibiotics, myths about “leaky gut,” and the impacts of stress, diet, and even posture on digestion. How Do I Know if My Gut is Healthy? Your Microbiome Questions, Answered - The New York Times (gift article).

Coach or Crutch? The Risks of AI in Your Health Routine

AI-powered health coaches are reshaping the wellness industry, promising real-time diet, exercise, and sleep guidance based on a user’s biometrics. However, there are substantial risks in relying on AI alone. These virtual coaches may offer inaccurate advice, potentially leading users to delay essential medical care. Additionally, biases in data collection, like inaccuracy for darker skin tones and conflicting advice with medical professionals, raise serious concerns. As companies like Whoop, Google, and Apple introduce these tools, experts caution that human oversight remains crucial, advocating for responsible integration rather than blind trust. AI Fitness Coaches from Whoop, Apple, and Google Promise Health Feedback and Improvement, But Are They Reliable?

Alan’s AI Assistant Steps Up to Boost Health Access

French health tech startup Alan has unveiled Mo, an AI-powered assistant designed to help its 680,000 members receive fast, reliable health advice. Mo supports Alan’s existing chat-based doctor consultations, offering medical guidance with the assurance of doctor oversight within 15 minutes to ensure accuracy. Alan also introduced two new features: a mobile shop with curated health products and “Alan Walk,” a gamified step counter that rewards users for staying active. These additions bring Alan closer to its vision of a comprehensive healthcare “super app” that combines insurance, wellness, and accessible care. Expansion plans include Canada, marking Alan’s first move beyond Europe.Alan unveils AI health assistant for its 680K health insurance members | TechCrunch.

Food Fight

The upcoming U.S. Dietary Guidelines are unlikely to include a clear directive to avoid ultra-processed foods despite their association with health issues like obesity and diabetes. A scientific advisory committee concluded there isn’t sufficient evidence to recommend limiting these foods, mainly due to research limitations, including reliance on observational studies. Critics argue that the committee set a standard for proof too high, ignoring key findings from smaller studies. This decision disappoints health advocates who believe caution is warranted to curb high rates of chronic illness tied to diet, especially within federal food programs. The Next Dietary Guidelines May Punt on Ultraprocessed Foods - The New York Times (gift article).

Why We Ghost

Ghosting, or the abrupt end of communication without explanation, is more than a dating phenomenon; it’s a cultural puzzle impacting friendships, family, and even long-term relationships. The article dives into why people ghost, from practical reasons like communication overload to complex psychological motives such as “destiny beliefs”—the notion that relationships are “meant to be” or not. Studies show ghosters often believe they’re sparing feelings, while ghostees experience emotional fallout, grappling with self-blame and unresolved hurt. Despite the pain, some ghostees find personal growth, viewing the experience as a chance for self-reflection. Why We Ghost - Nautilus.

The Science Behind Your Doppelgänger

Scientists have long been intrigued by doppelgängers—unrelated individuals with uncanny physical resemblance. Molecular geneticist Manel Esteller’s research, using François Brunelle’s “I’m Not a Look-Alike!” project, reveals that these look-alikes often share specific genetic traits related to facial structure, pigmentation, and bone length. While facial similarities stem from shared genetic variants, personality traits do not correlate, as psychologist Nancy Segal’s studies show. The findings suggest that genetic makeup can influence appearance but not personality. With global populations rising, genetic resemblances between strangers have become more common, sparking curiosity about our “twin strangers.” The surprising science behind doppelgängers.

Sleep Solutions for Every Age

How Much Sleep Do You Need? Tips for Better Slumber at Every Age - The New York Times (gift article) explores how sleep needs evolve across different life stages. From the newborn’s chaotic schedule to the early riser tendencies of older adults, the article provides age-specific recommendations and tips for restful sleep. Experts emphasize adjusting bedtime routines, managing environmental factors, and addressing common challenges like stress, screen time, and caffeine. Tailored guidance for each age group—from toddlers to retirees—ensures readers can optimize sleep patterns to feel more refreshed and energetic.

Mind Over Matter: Filtering Out the Noise

Contrary to the “spotlight” metaphor, the brain’s attention mechanism functions more like a filter, dimming irrelevant stimuli rather than highlighting important ones. Neuroscientist Michael Halassa’s research reveals that subcortical regions, particularly the thalamic reticular nucleus (TRN) and basal ganglia, play a crucial role in managing sensory data by suppressing distractions directed by the prefrontal cortex. This mechanism supports efficient focus, guiding attention by removing sensory “clutter” early in the process. These insights reshape our understanding of attention, consciousness, and the intertwined nature of perception and action. To Pay Attention, the Brain Uses Filters, Not a Spotlight | Quanta Magazine.

Shocking Revelation: Consciousness Sparks Beyond Neurons

In Consciousness Might Hide in Our Brain’s Electric Fields | Scientific American, Tamlyn Hunt argues that ephaptic field effects—subtle electric fields generated by neurons—may play a more crucial role in our awareness than previously believed synaptic firings. Traditional neuroscience emphasizes neurons’ electrical spikes as the brain’s primary communicative mechanism. However, studies, including a notable one by Dominique Durand, reveal that these fields enable ultra-fast, non-synaptic brain interactions. This electromagnetic coupling could potentially explain the rapid information processing that underlies cognition, challenging the long-held “neural code” model and sparking fresh insights into the mystery of consciousness.

107 - Booze and Bugs, Sound Health, and Akkermansia - HealthHippieMD Week In Review

Routine Recall

Sticking to repetitive routines might seem beneficial, but research reveals it can harm memory and cognitive function. Breaking free from habitual activities, such as doing the same workouts or eating the same meals, can improve mental stimulation, rewire your brain, and even increase happiness. Diversifying daily activities like cooking new recipes, learning new skills, or engaging in varied physical exercises promotes neuroplasticity and better cognitive health. Simple changes help stimulate the brain, enhance memory, and foster a greater sense of well-being. Keep your brain active by embracing novelty and variety. The #1 Habit to Break to Improve Your Memory.

Parkinson's Disease May Start in the Gut

A recent study adds weight to the theory that Parkinson's disease might originate in the gut rather than the brain. Researchers found that damage to the gastrointestinal lining, such as ulcers and esophagitis, increased the likelihood of developing Parkinson's later in life. The results support the "gut-first" hypothesis, which posits that misfolded proteins in the gut could spread to the brain through the vagus nerve, contributing to the onset of Parkinson's. Early detection and treatment of gut issues may be crucial in reducing this risk. Parkinson's may begin in the gut, study adds to growing evidence - The Washington Post (gift article).

Brain Fluid's Far-Reaching Voyage

Recent research reveals cerebrospinal fluid (CSF) may travel far beyond the brain and spinal cord, challenging long-held beliefs. Researchers injected fluorescent tracers and gold nanoparticles into mice's brain chambers and discovered the fluid reached peripheral nerves like the sciatic nerve. This breakthrough suggests CSF and peripheral nerves interact in ways not previously understood, potentially revolutionizing drug delivery to otherwise hard-to-reach nerves. While much is still unknown, these findings open new doors in neuroscience and pain management, especially for conditions like Ehlers-Danlos syndrome. Brain fluid may travel to distant parts of body | Science | AAAS (Thanks, Amy!).

Age is Just a Number (or is it?)

How much does aging affect mental acuity? It's debatable explores the complex relationship between aging and mental acuity, debunking common misconceptions about the elderly and cognitive decline. It highlights that age alone doesn't determine mental function—factors like lifestyle, genetics, and environmental influences play pivotal roles. While aging can affect reaction time and memory, the brain retains adaptability through new learning strategies. Cognitive frailty, distinct from dementia, can signal increased vulnerability to stress, but it isn't inevitable. The piece urges regular cognitive screenings, physical activity, and social engagement to support healthy brain aging and prevent mental decline.

Sound Health

The National Center for Complementary and Integrative Health of the NIH is considering expanding its Sound Health Initiative. The Sound Health Initiative aims to: 1. expand current knowledge and understanding of how listening, performing, or creating music involves intricate circuitry in the brain that could be harnessed for health and wellness applications in daily life, 2. explore ways to enhance the potential for music as therapy for neurological disorders, 3. identify future opportunities for research, and 4. create public awareness about how the brain functions and interacts with music. The NIH is requesting information to build research capacity through career-stage training programs potentially. Request for Information (RFI): Inviting Comments on Early Career Stage Training Programs to Support Capacity Building for Music and Health Research | NCCIH. +see also: Information from the joint NIH/National Endowment for the Arts December 2023 Workshop: Music as Medicine: The Science and Clinical Practice | NCCIH

The Thick Truth About Akkermansia

Akkermansia muciniphila, a probiotic microbe, is gaining attention for its potential health benefits, including weight management, better blood sugar control, and stimulating satiety hormones. While studies suggest higher levels of Akkermansia are linked to better metabolic health, its role is still under scrutiny due to limited research and possible side effects, including heightened vulnerability to pathogens. Despite the buzz and celebrity endorsements, experts urge caution and recommend prioritizing diet and exercise for gut health before turning to expensive supplements like Pendulum's probiotic products. A probiotic called Akkermansia claims to boost health. Does it work? - The Washington Post (gift article).

Buy Less, Do More

Buy Experiences instead of Possessions to Build Social Connection | Scientific American explores how purchasing experiences, rather than material goods, fosters deeper social connections. Research shows that shared experiences, like attending a concert or hiking, create a stronger sense of kinship than owning similar material items. Even when experiences differ in quality, they encourage bonding more than possessions. Reflecting on experiences also promotes a broader connection to humanity, countering loneliness and enhancing well-being. The article suggests prioritizing experiences over things for personal happiness and social cohesion and encourages policymakers to invest in public spaces for shared activities.

Booze and Bugs

How Does Alcohol Affect Your Gut Health? - The New York Times (gift article) explores the complex relationship between alcohol consumption and the gut microbiome. Heavy drinking can lead to imbalances in gut bacteria, inflammation, and a "leaky gut" that releases toxins into the bloodstream, potentially damaging the liver. While moderate alcohol consumption may not have the same harmful effects, research on its long-term impact is limited. Studies suggest red wine improves microbial diversity due to polyphenols, but reducing alcohol consumption is recommended to promote overall gut health and reduce the risk of various diseases.

Processed Predicaments

Are Some Ultraprocessed Foods Worse Than Others? - The New York Times (gift article) delves into a recent study analyzing the varying health risks associated with ultra-processed foods. Researchers found that certain types, like sugar-sweetened drinks and processed meats, pose a greater risk for cardiovascular disease than others, while some foods, like cereals and yogurts, might even offer nutritional benefits. The study emphasizes distinguishing between harmful and less harmful ultra-processed foods and recommends prioritizing whole, unprocessed foods for better health. Reducing processed meats and sugary beverages remains a crucial takeaway for healthier eating.

095 - Criticism, Landfills, and Tripping with Toad Venom - HealthHippieMD Week In Review

Dream On

Recent research has made significant strides in understanding sleep. Scientists have discovered more about lucid dreaming and how our brains replay memories during sleep. They've shown that sleep deprivation disrupts brain connectivity, impairing learning and emotional regulation. Furthermore, quality sleep is essential in preventing neurodegenerative diseases by clearing harmful toxins. Finally, new treatments like cognitive behavioral therapy for insomnia (CBT-I) are proving effective in enhancing sleep quality. These breakthroughs highlight the critical role of sleep in overall health and cognitive function. These 5 Sleep Science Breakthroughs Might Help You Get Better Rest.

+see also: Why We Sleep: Unlocking the Power of Sleep and Dreams.

Non-Meditative Mindfulness

Ellen Langer is a psychologist at Harvard who studies the mind-body connection. She's published some of the most counterintuitive studies in Social Science. I learned a lot from this podcast about her work and the history and importance of mindfulness. ‎People I (Mostly) Admire: 133. Pay Attention! (Your Body Will Thank You).

Toadally Psychedelic

5-MeO-DMT, a potent psychedelic from the Sonoran Desert toad, is renowned for its rapid, intense effects. While it holds promise for treating mental health disorders like depression and PTSD, its extraction threatens the toad population. Scientists are developing synthetic versions to alleviate this issue and ensure controlled dosing. Research highlights potential therapeutic benefits and the need for cautious, ethical approaches. As interest in psychedelics rises, the balance between medical advancement and environmental conservation remains crucial. The Promise — And Perils — Of 5-MeO-DMT.

+listen also: my favorite story EVER on NPR: The Dog that Loved to Suck on Toads.

Trimming the Fat on Global Obesity

France bucks the global obesity trend, dropping rates from 10.4% in 1990 to 9.7% in 2020. This contrasts starkly with countries like Egypt and the U.S., where rates have more than doubled. The Programme National Nutrition Santé, launched in 2001, is vital to France's success, focusing on improved nutrition and exercise. The initiative includes public campaigns like Manger Bouger, promoting healthier lifestyles. Meanwhile, Germany's obesity rates have plateaued due to a cultural shift towards healthier eating among younger generations. There's no magical cure, but these nations highlight the impact of proactive health policies and lifestyle changes. How is France dodging the global obesity trend?

Oh, Oh, Oh, Ozempic

Ozempic and other GLP-1 agonists, initially designed for diabetes, now offer benefits beyond weight loss, including reduced risk of heart disease and sleep apnea and potentially aiding in conditions like Alzheimer's and fertility issues. These drugs, often termed a "Swiss Army knife" for health, show promise in treating various ailments through mechanisms involving blood sugar control, organ-specific actions, and reduced inflammation. However, distinguishing the direct effects from those related to weight loss remains complex, and ongoing research is crucial to understand and fully utilize these multi-functional medications. Is Ozempic an Obesity Drug, or an Everything Drug? - The Atlantic.

The Dark Side of Plant-Based Diets

Ultra-processed plant-based foods, such as french fries and pastries, are linked to an increased risk of cardiovascular disease, according to a new study in The Lancet Regional Health-Europe. Research involving 118,000 UK adults reveals that while plant-based diets are beneficial, their health advantages vanish when the foods are ultra-processed. These findings suggest that minimally processed plant-based foods significantly lower the risk of fatal and nonfatal cardiovascular events, unlike their ultra-processed counterparts, which strip away essential nutrients and disrupt the food matrix, undermining heart health. These Ultra-Processed Plant-Based Foods Might Increase the Risk For Many Diseases.

Space Oddities

Four private astronauts spent three days in space aboard Inspiration4, experiencing significant, albeit temporary, changes in their bodies and minds. Research revealed cognitive declines, immune stress, and genetic alterations. Despite returning to normal post-mission, these findings highlight gaps in space medicine. The mission's data, stored in the Space Omics and Medical Atlas, is crucial for future space travel. From diverse backgrounds, the astronauts contributed invaluable insights into the physiological impacts of space, setting the stage for more tailored health measures for upcoming private space missions. Four Astronauts Spent 3 Days in Space. Here's What It Did to Their Bodies and Minds. - The New York Times (gift article).

White House Plans Diet for Landfills

The Biden administration introduced a national strategy to combat food waste, aiming to reduce the 30% of the U.S. food supply in landfills. The plan focuses on extending food shelf life, increasing food donations, and promoting composting. Despite these efforts, the strategy needs to include new regulations and catch up to some state and international laws. Key initiatives include research funding, consumer education, and collaboration with farmers and businesses. Critics view the plan as a positive but insufficient first step towards halving food waste by 2030. White House Takes a Tiny Bite From Giant Pile of Food Waste - The New York Times (gift article).

What Children Remember

Happy Father's Day! The Atlantic published a curated list of stories on fathers. I'm working my way through the list. What children remember - The Atlantic.

Criticism: The Gift That Keeps on Giving

In today's feedback-driven world, mastering the art of receiving and giving criticism is essential for personal happiness and professional growth. Criticism, significantly negative, is challenging to accept due to its impact on our brains and emotions. People with low self-esteem or high competitiveness struggle the most. Individuals can thrive by depersonalizing feedback, viewing it as insider information, and using it constructively. Criticism should be given with care, respect, and good intentions, always privately if negative. Embracing these practices can lead to improved well-being and performance. How to Take—And Give—Criticism Well - The Atlantic.

Gut Instincts

Microbiome research has traditionally focused on stool samples, but recent advancements allow scientists to explore the small intestine, revealing critical insights into gut health. The small intestine microbiome plays a crucial role in digestion, metabolism, and immunity. Disturbances in this area are linked to conditions like IBS, SIBO, and Celiac disease. New technologies like camera capsules facilitate better understanding and treatment development. This shift from focusing solely on the colon to including the small intestine promises significant advancements in microbiome medicine and gut health therapies. Poop has been an easy target for microbiome research, but voyages into the small intestine shed new light on ways to improve gut health.

080 - Entrepreneurial Hearts, Microbial Moodiness, and an Ode to Pop-Tarts - HealthHippieMD Week In Review

I increased the number of articles today since I won't publish a newsletter next week. The newsletter will return on March 3, 2024.

Tidying Up for Sanity

"The average person likely loses 5 percent of their time due to disorganization. Take your annual salary, multiply that by 5 percent, and you can measure what disorganization may be costing you." In Being organized can improve mental health. This is why., Daryl Austin explores how organization can positively impact mental health. Research suggests that living in a cluttered environment is associated with memory issues, poor eating habits, mood disorders, and decreased impulse control. It also is associated with increased stress levels, affecting overall well-being. However, organizing can enhance productivity, reduce exhaustion, and improve quality of life. Experts recommend starting small, setting aside specific time for decluttering, and enlisting support if needed. Digital decluttering is also emphasized. Ultimately, organizing sends a message of self-worth and can lead to a more intentional and loving relationship with one's home.

Aging Gracefully

As life expectancy increases, researchers are shifting focus from merely extending lifespan to enhancing healthspan—the years free from debilitating diseases. Key strategies include studying centenarians for genetic insights, promoting healthy lifestyles through diet, exercise, and mental engagement, and exploring experimental medications like metformin and rapamycin. Self-monitoring and social connectivity also play pivotal roles. While the quest for longevity continues, experts stress the importance of prevention and personalized approaches to optimize healthspan and ensure a healthier, more fulfilling life as we age.It's not your life span you need to worry about. It's your health span.

Long COVID's Exercise Paradox

A recent study sheds light on why many long COVID sufferers struggle with exercise. Post-exertional malaise (PEM), a defining symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), leads to a debilitating cycle of fatigue and worsened condition in Long-COVID patients. The study reveals that after exercise, these patients experience muscle damage, changes in muscle composition, and disrupted energy metabolism. Notably, they exhibit lower energy-generating processes and an impaired ability to recover from exercise. These findings underscore the importance of pacing oneself to minimize the severity and duration of post-exertional malaise in long COVID patients. Long COVID can destroy your ability to exercise. Now we know why.

Wired for Sound

Exploring the neuroscience of musical preference reveals intriguing connections to our personalities, emotions, and social identities. Our brains are naturally drawn to music with unexpected elements, triggering pleasurable responses. Studies show that our musical tastes evolve, influenced by our emotions and experiences. This suggests a deep link between music preference and personal identity. Understanding these connections can help bridge gaps between individuals with different tastes, highlighting musical enjoyment's universal and individual aspects. The Neuroscience of Musical Tastes - Neuroscience News.

Mastering the Apology

Why is it so challenging to deliver a genuine apology? Experts say a sincere apology requires vulnerability and humility, admitting wrongdoing without justifications or excuses. Research shows that effective apologies can lead to forgiveness, benefiting both the giver and the receiver. To craft a meaningful apology, experts suggest expressing regret without using conditional language, explaining the offense briefly, acknowledging the harm caused, promising not to repeat the mistake, offering to make amends, and gently requesting forgiveness. These steps can help repair relationships and foster understanding. How to Apologize Like You Mean It - The New York Times (gift article).

Self-Training Paradox: AI's Strange Evolution

As AI evolves, researchers turn to self-training methods, using machines to teach machines. This approach, while promising, raises concerns about the technology's opacity and potential to produce "unintelligible intelligence." With AI models already exhibiting complex behaviors and the ability to "cheat" in tasks, the path to actual artificial teaching is fraught with challenges. While self-training could lead to groundbreaking discoveries and efficiencies, it also poses risks of reinforcing biases and producing outcomes humans struggle to understand or control. As AI advances, so does the need to consider its capabilities and implications carefully. Things Get Strange When AI Starts Training Itself - The Atlantic.

Ageless Wonders

From the depths of the oceans to the ancient lands, Earth's inhabitants boast lifespans that defy human comprehension. Bowhead whales roaming Arctic waters can live over 200 years, while Jonathan, the Seychelles giant tortoise, has thrived for over 190 years. By unlocking the secrets of these long-lived creatures, scientists aim to understand the complex interplay of genetics, environment, and lifestyle that contributes to their exceptional lifespans. What Is the Longest Living Animal? From Tortoises to Whales | HowStuffWorks.

Memory Meltdown

A night of less than six hours of sleep can significantly impact your short-term memory, impairing your ability to recall information the next day. Sleep-deprived individuals may also experience reduced attention, emotional instability, and difficulty encoding new information. Lack of sufficient sleep can negatively affect the brain's frontal lobe, impacting memory retrieval and executive function. While remote memories remain intact, short-term memory and cognitive performance decline with each additional hour of missed sleep. Proper rest is crucial for memory consolidation and overall cognitive health. How Sleep Deprivation Can Affect Memory - The New York Times (gift article).

An Ode to Pop-Tarts

The passing of Bill Post, one of the creators of Pop-Tarts, stirs memories of this iconic childhood treat. Originally released in Cleveland 60 years ago, Pop-Tarts have become a pop-culture phenomenon, evolving into various forms and flavors. From the classic Frosted Pop-Tarts to the quirky Ted's Tarts knockoffs, these toaster pastries have captured hearts and taste buds. Comedians like Jerry Seinfeld have even immortalized them in routines. As we remember Post's legacy, we also celebrate the enduring appeal of these sweet treats that symbolize American nostalgia (and ultra-processed food). A toast to Pop-Tarts, the childhood treat I couldn't resist - The Washington Post (gift article).

Mood Mice-robials

Recent research has shown that the bacteria in your gut, particularly strains of Lactobacillus, can significantly influence mood and stress resilience. Studies on mice have revealed that specific bacterial strains can reduce stress and anxiety-like behavior, suggesting a direct link between the gut microbiome and mental health. This research opens new avenues for developing probiotics that target mood regulation, highlighting the importance of a healthy, probiotic-rich diet for mental well-being. Bacteria in your gut can improve your mood − new research in mice tries to zero in on the crucial strains.

Funny Bone-obos

Research conducted by Erica Cartmill and her colleagues reveals that great apes, including chimpanzees, bonobos, orangutans, and gorillas, engage in playful teasing behaviors resembling humor's building blocks. These actions, which include prodding, tickling, and stealing, are believed to have evolved over 13 million years ago and may serve to strengthen social bonds and provide insight into the tolerance levels of their peers. The study, which analyzed 75 hours of footage from two zoos, suggests that these behaviors demonstrate social intelligence and foresight, as successful teasing requires understanding others' psychological boundaries. This research sheds light on the early precursors of joking and the complex social dynamics within great ape communities. Great Apes Possess the Building Blocks of Humor - The Atlantic.

The Entrepreneurial Heart

In an article by Arthur Brooks for The Atlantic, the author parallels romantic love and entrepreneurship, suggesting that both ventures require a healthy attitude towards failure for ultimate success. Brooks argues that just as aspiring entrepreneurs must be prepared for the likelihood of failure, individuals seeking love must also embrace the possibility of heartbreak. He suggests that, much like failed business ventures, failed romances offer valuable lessons that can lead to greater happiness in future relationships. The article emphasizes the importance of learning from romantic failures, avoiding the "doom loop" of repeated mistakes, and maintaining a positive outlook on love despite setbacks. By adopting an entrepreneurial mindset, individuals can increase their chances of finding true romance.What to Do If the Course of True Love Is Not Running Smoothly - The Atlantic.

068 - Mitophagy, Crapsules, and VR for Pain - HealthHippieMD Week In Review

Artificial Inaccuracy

The article ChatGPT Quickly Authored 100 Blogs Full of Healthcare Disinformation, discusses a study where generative AI, particularly ChatGPT, was used to produce a large volume of healthcare disinformation rapidly. ChatGPT created 102 blog articles with over 17,000 words of disinformation on vaccines and vaping in just 65 minutes. The study, conducted by Australian researchers and reported in "JAMA Internal Medicine," also involved using AI tools like DALL-E 2 and HeyGen to create realistic images and a deep-fake video to accompany the blog posts. Notably, other AI programs like Google Bard and Microsoft Bing Chat did not facilitate such disinformation production. The study underscores the potential misuse of AI in spreading persuasive, customized disinformation efficiently, posing significant risks if exploited by malicious actors.

Dose of Reality: Unraveling the Complex Prescription Drug Financing in the U.S.

The article Following the Money: Untangling U.S. Prescription Drug Financingprovides a critical analysis of America's high prescription drug costs. It reveals that the U.S. leads in per capita drug spending, averaging $1,432 per person in 2021. This in-depth investigation into the U.S. healthcare system uncovers the multifaceted reasons behind this substantial financial burden. The article aims to shed light on the convoluted nature of prescription drug financing in the U.S., contrasting it with its international counterparts.

The Honest Truth About Fibs

Recent research reveals intriguing insights into lying habits. Surprisingly, 59.9% of people reported not lying in a day, with half of all lies coming from just 5.3% of participants. The study found that the frequency of lying is relatively unaffected by the communication medium, whether face-to-face, text, or email. Additionally, while minor lies are commonly told to strangers, significant lies are often reserved for close partners or family members. These findings, although reliant on self-reported data (leading to the possibility of significant inaccuracy), suggest that most people are generally truthful in their daily interactions. A New Study Estimated The Number of Times An Average Person Lies Per Day.

U.S. Dietary Guidelines Eyeing Ultra-processed Food

The upcoming revision of the U.S. dietary guidelines may mark a significant shift in nutritional focus by potentially warning against consuming ultra-processed foods. This change, influenced by mounting evidence linking these foods to a range of chronic diseases like obesity, heart disease, and diabetes, could profoundly impact national food programs, including the National School Lunch Program, and the overall dietary habits of Americans. Critics have long criticized current guidelines for overlooking the effects of food processing and additives. The food industry, fearing potential impacts, has already begun lobbying against such recommendations. The next guidelines edition is due in 2025, with an advisory committee report expected next year, potentially leading to a major overhaul in how Americans perceive and consume food. Nutrition guidelines may soon warn against ultra-processed foods - The Washington Post. (gift article)

FTC Takes a Bite Out of Misleading Influencer Marketing of Food

The FTC has warned significant food and beverage industry groups and numerous dietitian influencers, spotlighting a crackdown on undisclosed paid advertising on social media. Targeting American Beverage and the Canadian Sugar Institute, alongside influencers with over 6 million followers, the FTC points out non-transparent endorsements of artificial sweeteners and sugary foods. This move, spurred by The Washington Post and The Examination investigations, aims to enforce clear disclosure standards across influencer marketing. It represents a significant shift in the FTC's approach, with potential fines exceeding $50,000 per violation, signaling a tougher stance against deceptive social media advertising practices. FTC cracks down on food industry for paid dietitian influencer posts - The Washington Post. (gift article)

Mitophagy and Aging

Scientists at the Buck Institute have made a breakthrough in understanding aging by focusing on mitochondria, the cell's powerhouses. Their study, published in Nature Aging, highlights a natural compound, Mitophagy-Inducing Coumarin (MIC), that extends the lifespan of Caenorhabditis elegans, a model organism in aging research. MIC boosts the cell's waste management system, mainly targeting old and damaged mitochondria for disposal, a process known as mitophagy, which naturally declines with age. This discovery could lead to new therapies for age-related diseases by enhancing autophagy, the body's innate rejuvenation process. However, while MIC has shown promising results in worms, further research is needed to determine its effects on human aging. New Anti-aging Molecule May Work By Keeping the Cell's "Powerhouse" Healthy.

Crapsules: The Future of Medicine

In the field of microbiome medicine, a revolutionary shift is underway. Medical teams are transforming donated fecal matter into pills to combat infections like Clostridium difficile. These "crapsules" represent a broader scientific awakening to the importance of the gut's microbiome. Fecal transplants have proven to be efficacious in treating Clostridium dificile (a common life-threatening gut infection, often seen after broad-spectrum antibiotic treatment). Researchers are now exploring advanced strategies, including metabolite manipulation and genetically engineered bacteria, to treat a range of conditions more effectively. The FDA's recent approval of Seres Therapeutic's SER-109, an oral microbiome therapeutic, signifies a major leap in this field. With companies like Seres Therapeutics and Vedanta Biosciences at the forefront, the future of microbiome medicine appears promising, moving beyond the crude efficacy of FMT towards more sophisticated treatments. Microbiome treatments are taking off. (disclosure: I own shares of Seres Therapeutics)

Virtual Reality: A Real Game-Changer in Pain Management

The pain is real. The painkillers are virtual reality. | MIT Technology Review discusses RelieVRx, a virtual reality (VR) system designed to manage pain. Unlike traditional painkillers, RelieVRx aims to teach patients pain relief strategies such as mindfulness, cognitive-behavioral therapy, and relaxation rather than just providing a distraction. The approach is based on "unlearning" physiological pain responses and reinforcing alternative coping mechanisms. This innovative method offers a new frontier in pain management, leveraging the immersive capabilities of VR technology.

061 - Dementia Cafes, Slowing Aging, Misery, and Mattering - HealthHippieMD Week In Review

Exercise and Brain Health

A recent study re-emphasizes the importance of aerobic AND strength training for brain health in our later years. "We found that those who incorporated aerobic exercises, such as swimming and cycling, and strength exercises like weightlifting into their routines – regardless of intensity and duration – had better mental agility, quicker thinking, and greater ability to shift or adapt their thinking." Aerobic and strength training exercise combined can be an elixir for better brain health in your 80s and 90s, a new study finds.

Build A Strength Training Habit that Sticks

I'm an avid walker but have a more challenging time making strength training part of my routine. The NY Times had an article about ways to make strength training a habit: Strength Training Beginners Guide: How to Make the Workout a Habit - The New York Times. (gift article)

Japan's Dementia Cafes

In Japan, where dementia poses a pressing national health challenge, a heartwarming establishment known as the "Cafe of Mistaken Orders" is making waves. This 12-seat cafe in Tokyo hires elderly individuals with dementia as servers once a month, offering them a chance to interact, stay active, and feel needed. Customers embrace their delightful mix-ups, creating a safe space where smiles outnumber forgotten orders. With Japan's aging population, these dementia cafes are a creative solution to address the chronic caregiver shortage and soaring elderly care costs. In aging Japan, dementia patients staff cafe of mistaken orders - The Washington Post. (gift article)

Sound Medicine: The Healing Power of Music

Music is now recognized for its potential to heal the mind and body. Recent research introduces the concept of "music medicine," highlighting the therapeutic benefits of actively engaging with music. Beyond a temporary mood boost, music has shown promise in alleviating symptoms of depression, anxiety, insomnia, and even reducing blood pressure. While music therapy involves professional guidance, music medicine involves simply listening to recorded music, making it accessible and effective. Music's ability to evoke emotions, entrain brain activity, and trigger neurochemical changes underscores its healing potential, offering a soothing prescription for life's woes. The big idea: could we use music like medicine? | The Guardian.

Food is Medicine Report

The Food is Medicine Institute at Tufts released "The True Cost of Food: Food is Medicine Case Study," a comprehensive report on how such an approach could have a myriad of health and economic benefits: Food is Medicine education could save millions of lives and billions of dollars.

If We Are What We Eat, We Don't Know Who We Are

The NY Times reviewed the new book, Ultra-Processed People: The Science Behind Food That Isn't Food: van Tulleken, Chris. I am adding this one to my reading list. Book Review: 'Ultra-Processed People,' by Chris van Tulleken - The New York Times.

Senolytics, Sirtuins, and the Race to Fight Aging

This month's Economist's Technology Quarterly focuses on the race to combat aging:

• Slowing human aging is now the subject of serious research
• Eating fewer calories can ward off aging
• Ageing bodies need to get rid of decrepit cells
• Some claim human lifespans can be lengthened indefinitely
• What the young can give to the old
• Fighting aging requires properly equipped cells
• Older genomes have more dodgy genes

One Man's Crazy Quest for Immortality

Time featured a story on Bryan Johnson, a tech entrepreneur developing a life-extension system called Blueprint. Some of the weirder parts of his regimen "include downing 111 pills daily, wearing a baseball cap that shoots red light into his scalp, collecting his stool samples, and sleeping with a tiny jet pack attached to his penis to monitor his nighttime erections." The story and hype made me nauseous. Bryan Johnson's Quest For Immortality | TIME.

Adding Life To Years

"It is not enough for a great nation to have added new years to life. Our objective must also be to add new life to those years." The New York Times featured an OpEd on the importance of healthspan, rather than longevity: Opinion | America's Next Public Health Moonshot Should Tackle Health Spans - The New York Times. (gift article)

Arthur Brooks on How to Banish Misery

Arthur Brooks wrote an article extracted from the thoughts of the philosopher Bertrand Russell: Eight Ways to Banish Misery - The Atlantic.

Science or Spin

In a world where skepticism runs deep, scientific research is scrutinized. Recent revelations by scientists admitting to manipulating their findings to secure publication have sparked controversy. Climatologist Patrick Brown confessed to simplifying his climate change paper for a top journal, while Kristian Andersen altered the language of a COVID-19 origins paper during peer review. While not fraudulent, such actions raise questions about the sincerity of research. While some argue it's a minor breach for the sake of dissemination, others worry about the downstream effects of insincerity, where subtle choices in research can sway public perception on topics like climate change and vaccines. The struggle for genuine scientific discourse continues amidst a landscape of doubt. The Banality of Bad-Faith Science - The Atlantic.

Mattering

"To matter, people must feel valued — heard, appreciated, and cared for — and like they add value in ways that make them feel capable, important, and trusted. It's a two-part definition: feeling valued and adding value." Mattering influences self-compassion, relationships, and achieving one's goals. Why 'Mattering' Is a Key Part of Mental Health - The New York Times. (gift article)

060 - CRISPR, Wellness Tech Warnings, and the Brain's Fountain of Youth - HealthHippieMD Week In Review

More on the Impact of AI on Science

More on how AI is revolutionizing science in the Economist: How scientists are using artificial intelligence (gift article) and Could AI transform science itself? (gift article).

CRISPR and the Microbiome

CRISPR pioneer and Nobel Prize winner Jennifer Doudna is focusing on the microbiome: Crispr Pioneer Jennifer Doudna Has the Guts to Take On the Microbiome | WIRED. I highly recommend Walter Isaacson's biography on Doudna: The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race.

Big Tobacco Stains the Food Industry

"In a broader and much less restricting sense," an executive wrote, "R.J. Reynolds is in the flavor business." Although Big Tobacco is no longer in the food business, they left a terrible legacy: Many junk foods today were made and marketed by Big Tobacco - The Washington Post. (gift article)

Is Junk Food Addictive?

Recent studies suggest highly processed foods may have addictive qualities akin to drugs. Rats opt for sugar over cocaine, even enduring electric shocks for the sweet treat. Humans display similar behavior, consuming processed foods to the point of vomiting and diarrhea post-bariatric surgery. Daily snacking on these foods can rewire our brain's reward circuits, mirroring the cravings induced by cocaine. "In 2022, scientists published an opinion piece in the journal Addiction arguing that highly processed foods should be classified as addictive based on a 1988 Surgeon General report on tobacco products." Food Can Be Literally Addictive, New Evidence Suggests - Scientific American.

Healthy Diet Lowers Dementia Risk

Wapo had an article on the importance of diet in staving off dementia. Recent studies suggest the benefits occur even when started later in life: Eating heart-healthy foods also helps lower your dementia risk - The Washington Post. (gift article)

PANDA-monium: Infections Unmask Childhood Psychiatric Illnesses

Many doctors remain unaware PANDAS (Paediatric Autoimmune-Neuropsychiatric Disorders Associated with Streptococcus and its counterpart, PANS (Paediatric Acute-onset Neuropsychiatric Syndrome), or dismiss them as fictitious. This ignorance results in misdiagnoses, inappropriate treatments, and even parental accusations. Recent research suggests these disorders stem from an autoimmune reaction post-infection. The changing perception may have broader implications for understanding infections' roles in psychiatric conditions (for both children and adults), offering hope for early intervention and effective treatment. How common infections can spark psychiatric illnesses in children. (gift article)

Plasma, Platelets, and PF4: Searching for the Brain's Fountain of Youth

Groundbreaking research in mice may have revealed a key to rejuvenating aging brains. Neuroscientists have uncovered that platelets, specifically a group of molecules called Platelet Factor 4 (PF4), play a vital role in the age-reversal process. Three interventions—transfusions of young blood, the hormone klotho, and physical exercise—all harness PF4 to deliver their benefits to the brain. When 22-month-old mice were injected with young blood plasma or PF4, their cognitive age reversed dramatically. These findings, independently discovered by three research teams, offer new hope for combating age-related cognitive decline and unlocking the secrets of brain rejuvenation. Scientists uncover how young blood rejuvenates aging brains | BBC Science Focus Magazine.

Animal Communication Unveils Surprising Parallels to Human Language

Researchers are uncovering fascinating connections between animal communication and human language. For years, the belief in an unbridgeable gap between human language and animal communication prevailed. However, recent studies challenge this notion, revealing that various species possess intricate vocal learning abilities, from mice to dolphins. These findings suggest that language-related capacities may exist on a continuum across the animal kingdom. Scientists are now delving deeper into deciphering the meanings and intricacies of animal communication, shedding light on the evolution of language and our shared cognitive landscapes with other creatures. The Animals Are Talking. What Does It Mean? - The New York Times. (gift article)

+How AI is being leveraged to decode animal communication: Can We Talk to Whales? | The New Yorker and ‎Unexplainable: Can we talk to animals? on Apple Podcasts.

When the CIA, Artificial Intelligence, and Healthcare Collide

Palantir's Reputation Stalks Its Bid for the UK's National Health Data | WIRED is an interesting article about how Peter Thiel's big data analytics company (and surveillance government contractor), Palantir, is courting Britain's National Health Service for access to their data. What possibly could go wrong?

Big Tech Knows Your Most Intimate Health Details

Your most intimate health details have become data points in the digital realm. Tech giants, often unbeknownst to users, accumulate a treasure trove of personal health information through online interactions, from therapy sessions to fitness apps. Recent cases, like BetterHelp's data-sharing debacle, have exposed the extent of this information harvesting, raising concerns about privacy violations and potential harm. While some believe federal laws like HIPAA shield health data, the truth is more complicated. A fragmented regulatory landscape, limited enforcement resources, and the rapid evolution of technology call for comprehensive data privacy legislation to keep pace with the digital age. What Big Tech Knows About Your Body - The Atlantic.

Build a Real Music Collection

This author cites why she owns her music collection and eschews streaming: Want to Enjoy Music More? Stop Streaming It. - The New York Times. (gift article)

048 - Mindfulishness, Alzheimer's and the Microbiome, VR Forest Bathing - HealthHippieMD Week In Revie

Alzheimer's and the Microbiome

In a groundbreaking study, researchers have discovered that alterations in the human gut microbiome can precede the cognitive declines associated with Alzheimer's disease. The study, led by experts in the gut microbiome and Alzheimer's research, found distinct differences in the gut bacteria of individuals in the preclinical stages of Alzheimer's, even before any visible symptoms emerge. The findings raise the possibility of using stool sample analysis to detect early risk for Alzheimer's, enabling earlier interventions to slow or halt its progression. Further research aims to determine if targeted dietary changes or probiotic treatments can effectively modify the gut microbiome and delay Alzheimer's development. Changes in Human Microbiome Precede Alzheimer's Cognitive Declines

Mindfulishness: Are Meditation Apps a Distraction Trap?

In the thought-provoking article, Your Phone Is the Wrong Place to Go for Mindfulness, the author explores the paradoxical nature of meditation apps and their relationship with smartphones. While mindfulness apps offer convenient access to meditation practices and promise to bring peace of mind, they also contribute to the ever-present distraction of smartphones. The article questions the effectiveness of using these apps on a device that is notorious for causing unfocus and stress. It highlights the need for mindful choices in our phone usage and suggests that true mindfulness may lie in disconnecting from the screen altogether.

When is Anxiety a Problem?

Anxiety disorders affect approximately 1 in 5 American adults. Understanding when anxiety becomes problematic is crucial. While anxiety can serve as a protective alarm system, persistent worry and interference with daily life may signal the need for evaluation and treatment. Dr. Petros Levounis, President of the American Psychiatric Association, sheds light on recognizing anxiety's red flags and the available treatments. Notably, the article also addresses the omission of older adults from the screening recommendations and emphasizes the importance of discussing emotional concerns with healthcare providers. When Is Anxiety a Health Problem? What to Know About New Screening Guidelines - The New York Times (gift article)

Unraveling Statins

Researchers have uncovered the long-standing puzzle surrounding the muscle-related side effects of statins, America's most popular drug for managing cholesterol. While investigating the genetic causes of limb-girdle muscle dystrophy, two independent groups of scientists unexpectedly identified mutations in the gene encoding the HMG-CoA reductase enzyme—the same enzyme statins inhibit to reduce cholesterol production. The discovery sheds light on the connection between a rare genetic disease and statins' common muscle-related side effects, offering potential insights for targeted treatments and improving the lives of severely affected patients. The Gene That Explains Statins' Most Puzzling Side Effect - The Atlantic

Forest Bathing in VR

Scientists are studying whether computer-generated forests have the same effect on health and well-being that natural forests do. "Forest bathing" might work in virtual reality too | MIT Technology Review

Dark Side of the Rainbow

In Pink Floyd, 'The Wizard of Oz' and Me, (gift article) a journalist shares his connection to the phenomenon that occurs when Pink Floyd's album "The Dark Side of the Moon" is played in sync with the movie "The Wizard of Oz." The article delves into the strange and surreal coincidences that arise from this synchronization and explores the journalist's role in popularizing the concept through his early internet presence. The story reflects on the cultural impact of this unique pairing and the enduring intrigue it continues to evoke.

Virtual Tours of the NIH

Are you curious about the history and footprint of the National Institutes of Health? You can now take a virtual tour: Virtual Tour | National Institutes of Health (NIH)

Canine Clinical Trials

Dog cancer research is helping drug development for humans and canines (gift article) is about driving advancements in the development of cancer drugs for both humans and canines. Comparative oncology, the study of cancers in companion animals, offers insights into human treatments and has gained momentum due to the high failure rate of cancer clinical trials using mouse models. Studying dogs provides advantages such as shared environmental factors, cleaner data, and easier data sharing, leading to potential breakthroughs in cancer treatment for both species.

The Brain as a Prediction Engine

"For as long as we've studied human cognition, we've believed that our senses give us direct access to the world. We see what's there—or so the thinking goes. But discoveries in neuroscience and psychology have turned this assumption on its head. What if rather than perceiving reality passively, your mind actively predicts it?" I just bought the book The Experience Machine: How Our Minds Predict and Shape Reality.

Trauma Hijacks the Prediction Algorithms of the Brain

The neuroscience of trauma is an interesting video featuring Dr. Lisa Feldman Barrett, who contends that trauma alters the prediction algorithms of the brain.

Anti-Prosopagnosiacs: Human Super-Recognizers Outshine AI in Facial Recognition

Current facial recognition technology has error rates ranging from 48 to 62 percent. To address this issue, police forces in London, Berlin, and Queensland have enlisted super-recognizers help—individuals with an innate talent for recognizing unfamiliar faces. Studies show that these human experts excel in challenging scenarios where AI falls short, such as low-resolution images or crowded environments. However, racial bias remains a challenge even for super-recognizers. Researchers aim to identify exceptional talents and uncover the secrets behind their extraordinary face recognition abilities. Police Are Using Human Super-Recognizers to Replace Facial Recognition Algorithms in Some Contexts.

End the Tyranny of Processed Food

"Anyone who's struggling with [food-related disease] as an individual should take their guilt and shame and transfer it outwardly to the corporations that are feeding us these addictive substances, to the governments doing nothing about it, and to the physicians and the social media personalities who keep telling us that this stuff is healthy. We must end the conflict of interest between the industry, politicians, doctors, and scientists. Only then can we tackle the problem." An opinion piece about the role of processed food in today's society. I agree with most, except for the part about physicians conspiring. The actual problem with physicians is a lack of understanding. It's Time to End the Tyranny of Ultra-Processed Food

Aspartame to be Declared Carcinogenic by WHO

The World Health Organization will reportedly categorize Aspartame/Nutrasweet as potentially carcinogenic. Aspartame: Key ingredient in Diet Coke set to be declared 'possible cancer risk' by WHO I also learned of a study last year (in mice) where aspartame increased anxiety and fear processing across generations.Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala

044 - Biophilic Design, Hallucinations, and Erasing Memories - HealthHippieMD Week In Review

Strobe Lights Induce Visual Hallucinations

Wired U.K. featured a story about Dreamachine, where people experience hallucinatory effects through stroboscopic lights and music. The project aims to explore the impact of stroboscopic lights on the brain and investigate the neural basis of visual experience. Participants, even with closed eyes, reported vivid and kaleidoscopic visual experiences. The Dreamachine's potential applications extend to mental health therapy due to the reported common emotion of peace experienced by participants. This Machine Makes You Hallucinate | WIRED

Erasing Psychedelic Trips for the Good of Science

To address criticisms of psychedelic research, scientists at the University of Wisconsin–Madison Transdisciplinary Center for Research in Psychoactive Substances conducted a pilot study involving eight individuals, exploring the possibility of combining psychedelics with memory erasure. The study addresses the challenge of studying psychedelics in traditional randomized clinical trials due to the subjective nature of the experiences and the role of expectations. By exploring innovative study designs, scientists strive to better understand psychedelics' effects and potential therapeutic applications. Scientists Gave People Psychedelics—and Then Erased Their Memory

The Whimsy of Honoring Body Donors

Medical students and faculty members across the United States are organizing gratitude ceremonies to honor body donors who have contributed to medical research and education. These ceremonies involve music performances, speeches, and artistic expressions, allowing students to express appreciation for the donors who have served as their "first patients." The ceremonies aim to re-humanize the donors, recognizing their selfless acts and the sacrifice made by their families. The events provide closure and foster a sense of gratitude while imparting essential lessons in ethics and professionalism. Honoring the Body Donors Who Are a Medical Student's 'First Patient' (gift article)

Conversational Receptiveness: Mastering the Art of Disagreement

To have better disagreements, change your words – here are four ways to make your counterpart feel heard and keep the conversation going discusses the importance of changing our words and behaviors during disagreements to foster productive conversations. Instead of solely focusing on persuading others, the research suggests adopting a communication style called "conversational receptiveness." This style involves four key elements: hedging claims, emphasizing agreement, acknowledging the opposing perspective, and reframing to the positive. By employing these techniques, conversations become less confrontational and more constructive, allowing both parties to feel heard and maintaining relationships.

Rousing Revelations: Some Mental Illness May Have Autoimmune Origin

WaPo published a story about a groundbreaking case involving April Burrell, a catatonic woman diagnosed with schizophrenia. Researchers discovered that lupus, an autoimmune disease, attacked April's brain, leading to severe symptoms. After targeted treatments, including immunotherapy, April regained consciousness after being trapped in her mind for over two decades. This discovery has the potential to revolutionize the care for psychiatric patients worldwide and reshape the way mental illnesses are diagnosed and treated, bringing hope to "forgotten souls" who were deemed untreatable. How autoimmune disease can attack the brain, cause psychiatric symptoms - The Washington Post (gift article)

Function Over Flaws

A revolutionary new health metric called human functioning could alter the treatment of chronic illnesses. Traditionally, health has been measured based on morbidity and mortality rates, focusing solely on disease and death. However, the proposed metric considers a person's illness and available resources to gauge their condition's impact on daily life activities. This approach aims to shift the healthcare system toward a patient-centered approach, promoting well-being and enabling individuals to live their best lives. This New Metric For Health Could Revolutionize How We Treat Chronic Illnesses

Byte-Size Nutrition

Artificial intelligence (A.I.) nutritionist apps are revolutionizing healthy eating by offering personalized diet solutions. These apps use A.I. algorithms to analyze data on an individual's blood sugar, microbiome, and other metabolic measurements. By understanding how different foods affect each person's body, these apps can suggest healthier meal options. While personalized nutrition is still evolving, A.I. programs hold the potential for addressing obesity, heart disease, and other health concerns. Here Come the Artificial Intelligence Nutritionists

+A reminder, buyer-beware when it comes to A.I. advice (although the chatbot mentioned in this article is different than ChatGPT): An Eating Disorder Chatbot Is Suspended for Giving Harmful Advice^4a50c0

Music and Health: The Evidence

The NCCIH has a web page focused on Music and Health: What You Need To Know.

Nature at Home: A Prescription for Well-being

WaPo had an article about the science-backed concept of "biophilic design" that promotes connecting with nature indoors. 7 ways to bring nature into your home, according to science. (gift article)

Green Brain: Brain Aging Delayed with Mediterranean Diet

A recent study reveals that a Mediterranean diet can slow brain aging. The research indicates that a mere 1% reduction in body weight resulted in brains appearing almost nine months younger. Greener Diet, Younger Brain: Mediterranean Diet Slows Brain Aging.

Ultra-processed Food and Sleep Quality

"No study had previously investigated what happens if we consume an unhealthy diet and then compare it to the quality of sleep after that person follows a healthy diet." In this small preliminary study, an unhealthy diet impacted each individual's sleep quality. Junk Food vs. Sleep: New Study Reveals Impact of Diet on Sleep Quality.