123 - Dog:Human Lookalikes, Midlife Marriage Makeovers, and Mental Health - HealthHippieMD Week in Review

Photo by Daniel Lloyd Blunk-Fernández on Unsplash

Happy New Year and welcome to the first issue of HealthHippieMD on Substack mirrored on Squarespace.. If you haven’t yet subscribed to the newsletter click on the “Subscribe” button in the menu and sign up. Eventually, I will fully transition the Newsletter to Substack and stop posting here.

This space is where wellness meets curiosity, blending evidence-based insights with a sprinkle of holistic wisdom. Together, we'll explore innovative approaches to health, the latest in wellness trends, and practical tips to help you thrive in body, mind, and spirit. Please help me grow our community by liking, commenting, or sharing what you read.

Thank you for joining me on this journey—let's grow, learn, and inspire each other to live our healthiest lives.

Be Inspired. Be Informed. Be Well.

Jeff Taekman, M.D.

01

Gut Check on Alzheimer's

Could a common gut virus hold the key to Alzheimer's? A groundbreaking study explores how the human cytomegalovirus may travel along the vagus nerve, stirring immune responses linked to dementia. "Our results indicate a complex, cross-tissue interaction between HCMV and the host adaptive immune response," researchers revealed. This cross-tissue dynamic may open the door to antiviral therapies, potentially slowing or preventing Alzheimer's progression. As researcher Benjamin Readhead puts it, "We're motivated to understand whether these findings have implications for clinical care." Could this be the tipping point in understanding Alzheimer's? Common Gut Infection Tied to Alzheimer's Disease.

02

Ink and Lymphoma: A Risky Canvas?

Tattoos are more than skin deep—they may affect your health. A population-based study reveals a startling 20% increase in lymphoma risk among tattooed individuals, likely tied to carcinogens in tattoo ink and the immune system's response. "The study underscores the importance of regulatory measures to control the chemical composition of tattoo ink," the researchers emphasize, highlighting the urgency as tattoo culture grows. The question lingers: Is beauty worth the risk, or is it time for a regulatory makeover? Tattoos Linked to Malignant Lymphoma-Medscape.

03

Relationship Tips for the New Year

From "repotting" friendships to navigating "yellow flags" in dating to making over your marriage, these expert-backed strategies invite a more profound connection in every relationship. "Grieving and digesting the limits of one another's human imperfections is a central part of long-term intimacy," says family therapist Terrence Real, encouraging self-reflection and mutual understanding. Whether tackling tough conversations or finding joy in shared moments, these tips might transform your connections this year. Strengthen Your Relationships in 2025 - The New York Times (gift article).

04

Mental Health Hacks for 2025

Small changes can make a big difference. Whether moving your body, quieting your inner critic, or learning to embrace uncertainty, these science-backed tips are designed to help you thrive. Mental Health Advice for 2025 - The New York Times (gift article).

05

Midlife Marriage Makeover

Middle age often brings more than gray hairs—it's also a critical juncture for couples. Experts share six essential questions to rejuvenate your relationship, from reflecting on your dreams to uncovering your role in recurring conflicts. "When couples revisit the qualities that first drew them together, it shifts the emotional climate of the conversation," psychologist Harriet Lerner suggests, offering a powerful way to rekindle intimacy. Questions to Ask Your Partner at Midlife, According to Couples Counselors - The New York Times (gift article).

06

Insomnia's Emotional Cost

Sleep deprivation doesn't just leave you tired—it reshapes your mood, your thoughts, and even your mental health. Chronic insomnia, described as "a fire that jumps the fence" by one sufferer, can create a vicious cycle where anxiety disrupts sleep, which in turn exacerbates mental health issues. Cognitive-behavioral therapy for insomnia (CBT-I) has been transformative for many, teaching strategies like reframing negative thoughts and breaking harmful associations with sleepless nights. Is the answer to better mental health lying in bed? How Sleep Affects Your Mood: The Link Between Insomnia and Mental Health - The New York Times (gift article).

07

Who Let the Lookalikes Out?

Do you and your dog share a striking resemblance? Science suggests it's not just coincidence. Psychologist Yana Bender notes, "People consistently match dogs and their owners in photographs, even when the resemblance is subtle." Beyond physical similarities, personality traits also align—extraverted owners often have sociable dogs, while more anxious individuals report pets with heightened stranger-directed fear. Are we choosing pets that mirror us, or are they learning from us over time? Why We Look Like Our Dogs.

08

Mastering Calm

Can a simple breath change your brain? Science says yes. From ancient yoga practices to modern neuroscience, intentional breathing techniques are a powerful tool against stress. Could the rhythm of your breath be the symphony your mind needs? How to use breathwork to calm your mind - The Washington Post (gift article).

09

GLP-1s: A Weighty Solution?

With the obesity epidemic spiraling into a trillion-dollar crisis, GLP-1 drugs offer hope for weight loss and chronic disease prevention. But who benefits—patients, or the bottom line? Will these medications revolutionize care or reinforce inequalities as the health ecosystem pivots? Growth of GLP-1s has implications for multiple stakeholders-Deloitte.

10

Weight-Loss Wonders

Could a lizard's venom hold the secret to curing addiction and preventing Alzheimer's? The unexpected benefits of GLP-1 drugs, born from obesity treatments, are reshaping medical landscapes. These "wonder drugs" may alleviate cravings, protect against heart disease, and slow brain degeneration. With pharmaceutical giants like Eli Lilly racing to unlock their full potential, the question arises: Are GLP-1s medicine's new multi-tool, or just a weighty fix?
https://arstechnica.com/health/2024/12/weight-loss-drugs-may-also-treat-addiction-alzheimers-and-heart-disease/

11

Mindfulness: A Practice of Remembering

What if mindfulness isn't just about calm but transformation? Returning to its Buddhist roots reveals a practice steeped in remembrance—not of the past, but of the present moment. Can you "remember" your way to a more meaningful life? Mindfulness is about 'remembering' − a practice of coming back to the now.

If you enjoyed this newsletter, please comment, like, or share on Substack. Until next week.....

Be Inspired. Be Informed. Be Well.

118 - Kindness, Humor, and Maple Syrup - HealthHippieMD Week In Review

Small Acts, Big Ripples

An upward spiral – how small acts of kindness and connection really can change the world, according to psychology research explores how small, intentional acts of kindness and connection can catalyze societal change. Drawing on psychology, the author highlights how collective “micro-activism” combats hopelessness by addressing cognitive dissonance and fostering empathy. Studies reveal that personal connections soften prejudices, shift attitudes, and strengthen communities, ultimately influencing societal structures. From bridging political divides to improving intergroup relations, Hinchey demonstrates the transformational potential of everyday compassion. By building intentional relationships, individuals spark a powerful “upward spiral” of positive change, proving that small actions can create impactful global ripples.

Why Humor Is Serious Business

According to psychologists, humor serves as an unconscious yet strategic coping mechanism, transforming stress into moments of joy and connection. By triggering laughter, it enhances creativity, broadens perspective, and offers physical benefits like improved breathing and relaxation. Socially, humor fosters bonds, yet it requires mindful application—misplaced or mean-spirited jokes can deepen divides. Experts caution against toxic positivity, suggesting humor be used in moderation, providing emotional reprieve while still processing life’s challenges. Ultimately, humor acts as a psychological balm, equipping us with “antibodies” to weather hard times.How Humor Can Help You Get through Hard Times | Scientific American.

The Science of Chuckles and Tickles

A study by Roza Kamiloglu at the Free University of Amsterdam identifies two core types of human laughter: tickling-induced and laughter sparked by everything else. Using 887 video samples and machine learning, researchers found that tickling laughter has unique acoustic traits that make it more recognizable, a feature possibly tied to its evolutionary roots in primate play and bonding. Unlike other laughter forms, which evolved later with human cognition, tickling laughs date back over 10 million years. These findings illuminate laughter’s role in social connection and its potential infectiousness. The two types of human laugh.

Sweet or Sour? The Truth About Sugar Substitutes

As consumers seek to reduce sugar intake, food manufacturers increasingly use artificial and natural sugar substitutes, such as stevia, monk fruit, and allulose, to meet demand. While these alternatives promise fewer calories, experts caution about their health implications. Research links artificial sweeteners to potential risks, including cancer, heart disease, diabetes, depression, and gut health issues. New “natural” substitutes may seem safer, but their long-term effects remain uncertain. Moderation is key, with experts advising reduced reliance on processed foods and careful label scrutiny to limit hidden sweeteners. Ultimately, a balanced diet of whole foods is the safest choice. Are newer sugar substitutes better for you than artificial sweeteners? - The Washington Post (gift article).

Sweet Benefits of Maple Syrup for Health

A clinical trial (partially sponsored by the Maple Syrup Industry) reveals that swapping refined sugars for maple syrup improves cardiometabolic health, reduces abdominal fat, and enhances gut microbiota. Published in The Journal of Nutrition, the study highlights maple syrup’s natural compounds, including anti-inflammatory polyphenols, which lower blood sugar, systolic blood pressure, and harmful gut bacteria while increasing beneficial strains. Participants consuming two tablespoons daily experienced notable health improvements over eight weeks. Researchers aim to expand these findings, solidifying maple syrup as a “smarter sweetener” and an effective tool in preventing metabolic diseases like diabetes and cardiovascular issues. Reducing Abdominal Fat: Researchers Uncover Surprising Health Benefits of Maple Syrup. (Thanks, Amy!).

How Fear Shapes Your Choices

Loss aversion, a cognitive bias rooted in human psychology, compels us to avoid losses rather than seek equivalent gains, often leading to risk aversion and suboptimal decisions. Stemming from evolutionary survival mechanisms, this bias influences various aspects of life, from investments to career choices. How Loss Aversion Controls Your Decisions Without You Knowing It explores its impact on decision-making, highlighting cases like Polaroid’s failure to adapt and the sunk cost fallacy’s grip. Strategies to counteract loss aversion include reframing outcomes, quantifying risks, conducting pre-mortem analyses, and building emotional resilience, enabling more balanced, growth-oriented decisions.

Brain Gains with a Little Strain

A Penn State study reveals that even light physical activity, such as walking or playing, can enhance cognitive processing speed, reversing four years of cognitive aging. By tracking 204 middle-aged adults through smartphone check-ins over nine days, researchers found mental speed improved after participants engaged in any physical activity, regardless of intensity. The findings suggest movement, not vigorous exercise, as the key to cognitive boosts. While the long-term effects remain uncertain, ongoing research aims to explore how daily habits influence brain health and dementia prevention, using cutting-edge digital tools to deepen understanding. Light exercise can yield significant cognitive benefits, new research shows.

ChatGPT Diagnoses Better than Doctors

A study revealed ChatGPT’s diagnostic prowess surpassed physicians, even when doctors used the chatbot. While ChatGPT achieved a 90% accuracy rate on medical case histories, doctors averaged 74-76%, highlighting overconfidence and underutilization of AI. Researchers noted doctors often disregarded ChatGPT’s insights, contradicting their initial assumptions. The findings underscore the untapped potential of AI as a “doctor extender,” emphasizing the need for better integration and training. Though AI’s linguistic models shine in diagnosis, the human-AI collaboration still faces hurdles rooted in trust and adaptation to technology’s full capabilities. ChatGPT Defeated Doctors at Diagnosing Illness - The New York Times (gift article).

Keep Calm and Carry On (Mindfully)

How to Stay Calm When the World Is in Chaos | Psychology Today, although written in 2020, is equally applicable today. The article explores strategies for maintaining composure in an increasingly chaotic world. It emphasizes acknowledging fear without letting it dominate, living with intention, and fostering inner peace. Suggestions include limiting exposure to anxiety-inducing news, setting boundaries with people who amplify distress, and taking small, meaningful actions to feel empowered. The piece highlights the role of mindfulness, particularly meditation, as a tool to anchor oneself in the present and reduce catastrophizing thoughts. Seeking support from trusted individuals or professionals is encouraged, reinforcing that while change is inevitable, inner resilience can help navigate uncertainty.

Tune Up Your Memories

Listening to music can change how you remember past events - The Washington Post (gift article) reveals how music can remix your memories, shifting their emotional tone. Research from the Georgia Institute of Technology shows that listening to emotionally charged music during memory recall can reshape how those moments are remembered. Brain scans revealed enhanced activity in emotional and memory-processing regions, suggesting music’s power to intertwine with and reframe past events. These findings open new possibilities for music-based therapies, particularly for PTSD and depression. Everyday soundtracks, too, might uplift your mood and subtly transform how you recall life’s moments in the future.

098 - Trust Falls, AI Lie Detection, and Surviving Trauma - HealthHippieMD Week In Review

NY Times Nutritional Nuggets

Nutrition experts share key takeaways to shape our diets. The Mediterranean diet remains a top choice for heart health and longevity. Despite past beliefs, red wine's heart benefits are outweighed by its risks. Avocados stand out for their rich nutrients while delaying morning caffeine lacks scientific support. Environmental concerns temper Shrimp's nutritional value, and reducing sodium intake is essential for many. Apple cider vinegar's benefits are selective, and managing IBS might be more effective with diet changes than medication. Lastly, stay hydrated sensibly and be cautious with ultraprocessed foods.Our Favorite Nutrition Takeaways from 2024, So Far - The New York Times (gift article).

Trust Falls: Mind Your Moves

Nonverbal cues play a critical role in building trust, often betraying our true feelings unconsciously. Mixed messages—like warm tones paired with crossed arms—can create mistrust. Trust hinges on congruence between words and body language. Incongruity, emotional leaks, and closed body language can undermine trust and cause suspicion. To foster trust, align your verbal and nonverbal communication, manage emotional awareness, and practice open body language. Conscious communication helps convey sincerity and reliability, which are essential for strong relationships and successful collaborations. Unconscious behaviors that make people not trust you.

Holo-Doc

Crescent Regional Hospital in Lancaster, Texas, has introduced a futuristic approach to telehealth with hologram technology via Holoconnects. Patients can now interact with doctors through a 7-foot-tall, 440-pound Holobox, offering a 3-D, life-like video experience for $42,000 plus annual fees. While proponents tout improved patient engagement and realistic interactions, skeptics question the benefits of traditional 2-D telehealth options. Critics argue that the high cost and limited data on improved care quality make it less practical for widespread medical use, though it shows promise in the physical therapy and hospitality sectors. Your Hologram Doctor Will See You Now - The New York Times (gift article).

America's Diet Dilemma

America's obsession with dieting spans over a century, reflecting a paradox of indulgence and restraint. Early 20th-century essays in The Atlantic highlight the cyclical nature of diet culture, where strict regimens follow periods of indulgence. By the 1920s, slimness equated to health and wealth, further embedding the societal pressure to lose weight. Despite numerous fad diets and the evolution of nutritional understanding, the fundamental misunderstanding of balanced eating persists. Modern weight-loss drugs like Ozempic may change the landscape, but as long as thinness is idealized, the diet culture will endure. America can't stop dieting - The Atlantic. ^

Tau-morrow's Diagnosis Today

UC San Francisco researchers have discovered a method to diagnose progressive supranuclear palsy (PSP) in living patients. Previously identified only post-mortem, PSP, often mistaken for Parkinson's, progresses rapidly and is fatal within seven years. A study in Neurology highlights the use of high-throughput technology to identify protein biomarkers in spinal fluid, differentiating PSP from other forms of frontotemporal dementia. This breakthrough could lead to early diagnostic tests and targeted therapies, offering hope for timely intervention. The study underscores the importance of early diagnosis to enhance treatment efficacy and improve patient outcomes. Scientists may have discovered how to diagnose elusive neuro disorder (Thanks, Amy!).

Arthur Brooks on Fixing Social Media

In this video, Professor Arthur Brooks discusses how social media harms our socializing ability and proposes a way to fix it. We're lonelier than ever — and there's one big reason - Big Think.

Surviving Trauma

On this podcast, Dr. Bessel van der Kolk, psychiatrist and author of The Body Keeps the Score, discusses understanding and dealing with lasting psychological trauma. It's well worth a listen. ‎How To!: How To Survive a Shark Attack (Encore).

Befriending Your Inner Voice

You know that negative voice that constantly berates you with negative self-talk? Thinking about anything else is hard when that inner chatter gets switched on. This podcast discusses how to keep our negative emotions from morphing into chatter. ‎Hidden Brain: Befriending Your Inner Voice.

Healthcare from Cradle to Cane

Designer Yves Behar argues that health care should cater to society's most vulnerable: children, older people, and those with disabilities. He critiques the sector for lagging in innovation compared to consumer experiences like those at an Apple Store. Behar's projects, like the AI companion robot Moxie for neurodivergent children and the FDA-approved SNOO bassinet for safe infant sleep, illustrate his vision. These designs address extreme needs and offer broader benefits, proving that inclusive design enhances everyone's experience. Health Care Should Be Designed for the Extremes of Life | WIRED.

AI Lie Detection

A study has shown AI outperforms humans in detecting lies, achieving a 67% accuracy rate compared to humans' 50%. Utilizing Google's AI model BERT, the tool identified falsehoods more effectively. However, reliance on AI led to increased accusations, raising ethical concerns about trust and social bonds. Despite skepticism, a third of participants trusted the AI tool's predictions, demonstrating its potential impact on evaluating claims and detecting misinformation. The study highlights the need for thorough testing before widespread implementation. AI lie detectors are better than humans at spotting lies | MIT Technology Review.

Mindful Matters

Despite its widespread promotion as a mental health cure-all, mindfulness may not benefit everyone equally. Research shows that the effectiveness of mindfulness practices varies with age. Older adults tend to experience better mental health by acting with awareness and being nonjudgmental, while younger individuals, who are more focused on observing, often see fewer benefits. A tailored approach to mindfulness, emphasizing aspects like nonjudgment for youth, could enhance its impact. Personalized mindfulness practices, reflecting one's age and specific needs, may be essential to unlocking its full potential. Here's Why You May Not Be Getting the Benefits You Expected From Mindfulness.

095 - Criticism, Landfills, and Tripping with Toad Venom - HealthHippieMD Week In Review

Dream On

Recent research has made significant strides in understanding sleep. Scientists have discovered more about lucid dreaming and how our brains replay memories during sleep. They've shown that sleep deprivation disrupts brain connectivity, impairing learning and emotional regulation. Furthermore, quality sleep is essential in preventing neurodegenerative diseases by clearing harmful toxins. Finally, new treatments like cognitive behavioral therapy for insomnia (CBT-I) are proving effective in enhancing sleep quality. These breakthroughs highlight the critical role of sleep in overall health and cognitive function. These 5 Sleep Science Breakthroughs Might Help You Get Better Rest.

+see also: Why We Sleep: Unlocking the Power of Sleep and Dreams.

Non-Meditative Mindfulness

Ellen Langer is a psychologist at Harvard who studies the mind-body connection. She's published some of the most counterintuitive studies in Social Science. I learned a lot from this podcast about her work and the history and importance of mindfulness. ‎People I (Mostly) Admire: 133. Pay Attention! (Your Body Will Thank You).

Toadally Psychedelic

5-MeO-DMT, a potent psychedelic from the Sonoran Desert toad, is renowned for its rapid, intense effects. While it holds promise for treating mental health disorders like depression and PTSD, its extraction threatens the toad population. Scientists are developing synthetic versions to alleviate this issue and ensure controlled dosing. Research highlights potential therapeutic benefits and the need for cautious, ethical approaches. As interest in psychedelics rises, the balance between medical advancement and environmental conservation remains crucial. The Promise — And Perils — Of 5-MeO-DMT.

+listen also: my favorite story EVER on NPR: The Dog that Loved to Suck on Toads.

Trimming the Fat on Global Obesity

France bucks the global obesity trend, dropping rates from 10.4% in 1990 to 9.7% in 2020. This contrasts starkly with countries like Egypt and the U.S., where rates have more than doubled. The Programme National Nutrition Santé, launched in 2001, is vital to France's success, focusing on improved nutrition and exercise. The initiative includes public campaigns like Manger Bouger, promoting healthier lifestyles. Meanwhile, Germany's obesity rates have plateaued due to a cultural shift towards healthier eating among younger generations. There's no magical cure, but these nations highlight the impact of proactive health policies and lifestyle changes. How is France dodging the global obesity trend?

Oh, Oh, Oh, Ozempic

Ozempic and other GLP-1 agonists, initially designed for diabetes, now offer benefits beyond weight loss, including reduced risk of heart disease and sleep apnea and potentially aiding in conditions like Alzheimer's and fertility issues. These drugs, often termed a "Swiss Army knife" for health, show promise in treating various ailments through mechanisms involving blood sugar control, organ-specific actions, and reduced inflammation. However, distinguishing the direct effects from those related to weight loss remains complex, and ongoing research is crucial to understand and fully utilize these multi-functional medications. Is Ozempic an Obesity Drug, or an Everything Drug? - The Atlantic.

The Dark Side of Plant-Based Diets

Ultra-processed plant-based foods, such as french fries and pastries, are linked to an increased risk of cardiovascular disease, according to a new study in The Lancet Regional Health-Europe. Research involving 118,000 UK adults reveals that while plant-based diets are beneficial, their health advantages vanish when the foods are ultra-processed. These findings suggest that minimally processed plant-based foods significantly lower the risk of fatal and nonfatal cardiovascular events, unlike their ultra-processed counterparts, which strip away essential nutrients and disrupt the food matrix, undermining heart health. These Ultra-Processed Plant-Based Foods Might Increase the Risk For Many Diseases.

Space Oddities

Four private astronauts spent three days in space aboard Inspiration4, experiencing significant, albeit temporary, changes in their bodies and minds. Research revealed cognitive declines, immune stress, and genetic alterations. Despite returning to normal post-mission, these findings highlight gaps in space medicine. The mission's data, stored in the Space Omics and Medical Atlas, is crucial for future space travel. From diverse backgrounds, the astronauts contributed invaluable insights into the physiological impacts of space, setting the stage for more tailored health measures for upcoming private space missions. Four Astronauts Spent 3 Days in Space. Here's What It Did to Their Bodies and Minds. - The New York Times (gift article).

White House Plans Diet for Landfills

The Biden administration introduced a national strategy to combat food waste, aiming to reduce the 30% of the U.S. food supply in landfills. The plan focuses on extending food shelf life, increasing food donations, and promoting composting. Despite these efforts, the strategy needs to include new regulations and catch up to some state and international laws. Key initiatives include research funding, consumer education, and collaboration with farmers and businesses. Critics view the plan as a positive but insufficient first step towards halving food waste by 2030. White House Takes a Tiny Bite From Giant Pile of Food Waste - The New York Times (gift article).

What Children Remember

Happy Father's Day! The Atlantic published a curated list of stories on fathers. I'm working my way through the list. What children remember - The Atlantic.

Criticism: The Gift That Keeps on Giving

In today's feedback-driven world, mastering the art of receiving and giving criticism is essential for personal happiness and professional growth. Criticism, significantly negative, is challenging to accept due to its impact on our brains and emotions. People with low self-esteem or high competitiveness struggle the most. Individuals can thrive by depersonalizing feedback, viewing it as insider information, and using it constructively. Criticism should be given with care, respect, and good intentions, always privately if negative. Embracing these practices can lead to improved well-being and performance. How to Take—And Give—Criticism Well - The Atlantic.

Gut Instincts

Microbiome research has traditionally focused on stool samples, but recent advancements allow scientists to explore the small intestine, revealing critical insights into gut health. The small intestine microbiome plays a crucial role in digestion, metabolism, and immunity. Disturbances in this area are linked to conditions like IBS, SIBO, and Celiac disease. New technologies like camera capsules facilitate better understanding and treatment development. This shift from focusing solely on the colon to including the small intestine promises significant advancements in microbiome medicine and gut health therapies. Poop has been an easy target for microbiome research, but voyages into the small intestine shed new light on ways to improve gut health.

084 - Digital Doppelgangers, Whispers in White Noise, and Optimism in Longevity - HealthHippieMD Week In Review

Digital Doppelgangers: Revolutionizing Diabetes Management

Twin Health has innovated a groundbreaking approach to managing type 2 diabetes by creating digital twins of the human body. These virtual avatars are built using multiple data points from sensors and AI algorithms to generate a personalized model of a patient's metabolism. The digital twin continuously learns from real-time data, offering tailored predictions and recommendations for managing blood sugar levels. In a clinical trial, patients using this technology saw significant reductions in blood sugar levels, with nearly 73% achieving remission after a year. The future of this technology promises a personalized and proactive approach to managing chronic diseases like diabetes, potentially transforming global healthcare standards. Interestingly, in 2014, I wrote a proposal for NLM and then NIDDK for this exact purpose. My proposal went unfunded, but seeing I was on the right track is rewarding. Digital twins are an effective new way to control your metabolism.

Sitting on a Time Bomb

A recent study by the University of California, San Diego (UCSD) has unveiled alarming findings about the health risks associated with prolonged sitting. Tracking 5,856 women aged 63 to 99 over a decade, researchers discovered that those sitting for more than 11 hours daily had a 57% higher risk of death compared to those sitting for less than 9.5 hours. Contrary to popular belief, even regular moderate-to-vigorous exercise couldn't offset the dangers of excessive sitting. However, an Australian study suggests that walking 9,000 to 10,500 steps daily could reduce the risk of premature death, even for habitual sitters. The discrepancies between studies might be due to different methods of measuring sitting time. The UCSD study's robust evidence underscores the importance of minimizing sitting time and breaking it up with periods of standing or walking, which aligns with World Health Organization guidelines. Sitting Is Even Deadlier Than We Thought, A New Study Reveals.

The Concussion Conundrum

The article explores the misconceptions surrounding concussion treatment, highlighting the story of Conor Gormally, who suffered multiple concussions. For years, the medical advice for concussion recovery emphasized total rest, but emerging research indicates that active rehabilitation, involving activities like exercise, reading, and screen time, is more effective. Despite this shift in understanding, many patients still receive outdated advice to "cocoon" themselves in rest, delaying their recovery. The article calls for a change in how concussions are treated, emphasizing the need for updated medical education and patient-centered care. Concussion: there's an insidious myth about a common sports injury. Even doctors believe it.

Optimism's Role in Longevity

The New Science of Optimism and Longevity explores the biological significance of optimism in promoting healthy aging and reducing disease risk. People with optimistic mindsets exhibit better cardiovascular, pulmonary, metabolic, and immunological health, leading to lower incidence of age-related illnesses and reduced mortality. A 2019 review found that optimists have a 35% lower risk of cardiovascular events and tend to live 11-15% longer than pessimists. The article also discusses the potential of optimism in slowing down cellular aging, as evidenced by studies on telomere shortening. While genetics play a role, optimism can be cultivated through social relationships and positive thinking practices, offering a strategy for enhancing physical and mental well-being.

Whispers in the White Noise

Have you ever heard mysterious voices or music in your white noise machine? You're not alone. This phenomenon, known as auditory pareidolia, occurs when your brain tries to match patterns in continuous noise, like white noise, with familiar sounds. It's a normal brain function, not a sign of schizophrenia or other psychological disorders. Experts explain that our brains are pattern-matching machines, constantly searching for recognizable sounds in the noise we hear. While it might be unsettling to listen to these phantom sounds, there's no need for concern unless you hear them without any noise present. If you're bothered by these sounds, try switching to a different type of noise or moving away from the source. Why You Hear Voices in Your White Noise Machine | WIRED.

The Impact of Electronic Music on Consciousness

Electronic music isn't just for dancing; it can also significantly alter our consciousness. Research shows that electronic music's repetitive beats and rhythms can induce trance-like states, impacting brainwave patterns and emotions. This effect is not only utilized by club-goers but also by therapists for meditation and relaxation. The article explores how electronic music's unique characteristics can influence our mental and emotional well-being, offering a new perspective on the power of music in shaping our state of mind. Brain beats: How electronic music can alter our state of consciousness. +see also Electronic music appears to alter our state of consciousness | New Scientist (subscription required)

Disconnect to Reconnect

Finding a healthy relationship with our devices is crucial in an age where technology is omnipresent. 5 Tips for a Healthier Relationship With Your Phone - The New York Times (gift article) offers practical advice for managing screen time without completely unplugging. Key suggestions include being mindful of automatic urges to check devices, limiting phone use while on the move, scheduling short tech breaks, creating an environment that encourages less phone usage, and ensuring that technology serves you, not the other way around. These tips help individuals regain control over their digital lives and foster a more balanced interaction with their gadgets.

Cool Your Jets

A comprehensive review of 154 studies by Sophie L. Kjaervik and Brad Bushman has revealed that traditional methods of managing anger, such as hitting a punching bag or jogging, may be ineffective. Instead, activities that decrease physiological arousal, like deep breathing, muscle relaxation, yoga, meditation, and mindfulness, have significantly reduced anger and aggression across various settings and populations. The research challenges the notion that venting anger is beneficial, highlighting that simple and accessible techniques can be more effective for anger management. This study offers evidence-based strategies for better anger control, promoting healthier outcomes and societal well-being. Chilling out rather than blowing off steam is a better way to manage anger − new review of 154 studies reveals what works.

081 - Mind Meld, Productive Conflict, and the Art of Saying No - HealthHippieMD Week In Review

NCCIH Relaxation Techniques

"Relaxation techniques help bring about the body's "relaxation response," characterized by slower breathing, lower blood pressure, and a reduced heart rate. The relaxation response is the opposite of the stress response." Here is an evidence fact sheet: Relaxation Techniques: What You Need To Know. | NCCIH

The Art of Saying "No" for a Happier You

In his article Overwhelmed? Just Say 'No.' - The Atlantic Arthur C. Brooks delves into the science of happiness and how saying "no" more often can lead to a more fulfilling life. He argues that the constant bombardment of demands and requests can overwhelm us and distract us from our happiness. Brooks identifies two main issues that contribute to this problem: hyperbolic discounting, which leads us to prioritize immediate pleasures over future benefits, and the fear of future regret, which can make us hesitant to decline opportunities. He suggests three strategies to combat these tendencies: forming a "No Club" for accountability, making "no" the default response, and adding friction to the process of saying "yes." By mastering the art of saying "no," Brooks believes we can focus more on our priorities and lead happier lives.

Long-Covid's Foggy Forecast

A comprehensive study in England involving nearly 113,000 participants has revealed that individuals with persistent post-COVID symptoms, commonly referred to as long-term COVID-19, exhibit a measurable decline in cognitive abilities, particularly in memory, reasoning, and planning. The study, published in The New England Journal of Medicine, found that those with long Covid scored the equivalent of 6 I.Q. points lower than those who had never been infected. Even individuals who had recovered from Covid-19 showed a slight decline in cognitive performance compared to the uninfected. However, the study also offers hope, suggesting that the associated cognitive impairment might improve if Covid symptoms ease over time. This research provides numerical evidence for the cognitive challenges many long Covid sufferers face and highlights the importance of understanding and addressing the long-term effects of the virus on mental function. Long Covid May Lead to Measurable Cognitive Decline, Study Finds - The New York Times (gift article).

Covid is NOT the Flu

Four years into the COVID-19 pandemic, the United States' approach to managing the virus increasingly resembles its handling of seasonal flu. Vaccines are updated annually, and the CDC is considering more flu-like isolation guidelines. Despite some similarities, COVID-19 and flu are distinct, with COVID-19 causing more hospitalizations and deaths and having a less predictable pattern. The trend towards treating COVID-19 as a routine illness raises concerns about diminishing precautions and the potential underutilization of treatments like Paxlovid. This shift may also obscure the ongoing impact of long COVID and reduce incentives for testing. While some policy convergence is understandable, experts worry that the U.S. is moving too quickly towards normalizing COVID-19 without adequately addressing its unique challenges. Why Are We Still Flu-ifying COVID? - The Atlantic.

Productive Conflict

"The goal. It isn't to avoid conflict. At the highest level, it's to recognize what kind of conversation you're having." Derek Thompson explores the insights from Charles Duhigg's book, "Supercommunicators," on improving communication in relationships. The article highlights the importance of recognizing the type of conversation, whether practical or emotional, to avoid unnecessary conflicts. It also delves into research from the 1970s by psychologists known as the "Love Shrinks," who studied how married couples navigate conflicts. Their findings revealed that all couples fight, but the key to a healthy relationship is not what they fight about but how they fight. Happy couples tend to focus on controlling themselves rather than their partners, avoid escalating the conflict, and use "I" statements instead of accusatory "you" statements. Thompson shares his realization of the importance of staying on topic during arguments, using the metaphor of not "opening new tabs" in a browser. The article suggests asking three brief questions during conflicts to improve communication: "Are we opening new tabs?" "Are we venting or problem-solving?" and "What if I tried to control only myself?" Three Ways to Have Better Fights - The Atlantic

The Neuroscience of Hanging Art

Arranging art on walls can be overwhelming, but incorporating whimsy and proportion can enhance enjoyment. Neuroscience suggests considering the viewer's perspective, with art ideally hung 56 to 60 inches above the floor. For groupings, prioritize special pieces, maintain spacing, and consider symmetry, which is psychologically pleasing. Planning layouts on the floor before hanging can ensure a satisfying arrangement. The article emphasizes that while there are guidelines, personal expression and creativity are key to a visually appealing display. How to hang art and photos to please the eye and the brain - The Washington Post (gift article).

Mind Meld

The Remarkable Ways Our Brains Slip Into Synchrony | The MIT Press Reader explores the fascinating ways in which our brains synchronize during shared experiences, a phenomenon increasingly supported by cognitive science research. This synchronization is evident in various scenarios, such as collaborating on a task, engaging in conversation, or sharing a meal. The merging of individual cognitions creates a fluid exchange of information, blurring the lines between separate entities. Experiments have shown that when people work together, their actions and even postural sways can become coordinated, resembling the behavior of a single system. This coordination extends to brain activity, eye movements, and gestures, enhancing empathy and rapport. The article highlights that effective communication is about exchanging messages and co-creating a shared experience, underscoring the deep interconnectedness of human cognition. (Thanks, Wendy)

Microbiome and Retinal Disease

Recent research suggests a surprising link between gut bacteria and inherited retinal diseases like retinitis pigmentosa, which can lead to blindness. The study, published in Cell, challenges the long-held belief that the eyes are shielded from bacterial invasion. Researchers found that mutations in the CRB1 gene, a leading cause of these diseases, weaken the protective barrier around the eye and the cell linkages in the colon, allowing gut bacteria to travel to the retina. Experiments with Crb1-mutant mice showed that depleting gut bacteria or treating with antibiotics reduced retinal damage, hinting at potential new treatments. However, experts urge caution, as the complexity of the disease and the role of bacteria are not fully understood, and antibiotics may not reverse the genetic damage. The surprising link between gut bacteria and devastating eye diseases. (Thanks, Amy)

078 - Panpsychism, Unleashing Joy, and Dream Teams - HealthHippieMD Week In Review

NCCIH on Mindfulness and Meditation

I wanted to remind you about the terrific National Center for Complementary and Integrative Health resources. Here is their fact sheet on Mindfulness and Meditation: Meditation and Mindfulness: What You Need To Know | NCCIH

The Dream Team

I thought I'd feature an article on the importance of sleep and athletics with the Super Bowl approaching. The significance of a good night's sleep is often overlooked. However, sleep is vital in enhancing athletes' performance, from boosting muscle repair to strengthening the immune system. This article highlights the crucial connection between quality sleep and athletic success. It explains the different stages of sleep and their impact on physical and cognitive health. Athletes prioritizing sleep can improve speed, accuracy, cognitive skills, and pain tolerance, ultimately gaining a competitive edge. The article also provides practical tips for athletes to optimize their sleep routines, emphasizing that sleep is a performance enhancer. Sleep can give athletes an edge over competitors − but few recognize how fundamental sleep is to performance.

+And if you're curious how exceptionally talented professional athletes are compared to the Average Joe, listen to this podcast (where a journalist went through the NFL combine and was rated against NFL players): People I (Mostly) Admire: 123. Walt Hickey Wants to Track Your Eyeballs.

A Fitness Folly

In The Apple Watch May Have a Calorie Problem, The Atlantic explores the complex relationship between users and their fitness trackers, particularly the notorious red "Move" ring on the Apple Watch. The article delves into the challenges users face in trying to meet daily activity goals set by these devices, revealing the potential pitfalls of relying on them too heavily. The piece highlights the inaccuracy of calorie measurements on fitness trackers and how these devices can sometimes lead users to prioritize external motivation over the intrinsic joy of staying active. Ultimately, it raises thought-provoking questions about the role of technology in shaping our fitness routines.

Edibles vs. Smoking Cannabis

As the popularity of cannabis-infused edibles surges, people are questioning whether they offer a safer alternative to traditional smoking methods. While the answer is not straightforward, experts weigh in on the pros and cons of each. Edibles take longer to kick in, making it easier to overconsume, potentially leading to adverse effects. They can also produce more intense highs. On the other hand, smoking poses respiratory risks due to harmful chemicals in the smoke, though conclusive evidence on lung cancer is lacking. Regardless of the method, cannabis use has some short and long-term health risks, emphasizing the importance of moderation and informed choices. Are Cannabis Edibles Safer Than Smoking? - The New York Times (gift article).

Panpsychism: Is Consciousness Woven into the Universe?

"Somehow, the water of the physical brain is turned into the wine of consciousness." In a thought-provoking article, Dan Falk explores the age-old question of consciousness and its place in the Universe. The article delves into the theory of panpsychism, which suggests that consciousness is an intrinsic component of reality, akin to mass or electrical charge. Scholars gathered at a recent workshop to discuss the idea, highlighting its appeal as a solution to the enigmatic "hard problem" of consciousness. However, critics argue that panpsychism faces challenges, such as the "combination problem" and the dilemma of explaining the consciousness of other beings. The article offers a captivating glimpse into the ongoing debate between panpsychism and alternative views, shedding light on the profound philosophical implications of our understanding of consciousness. Is Consciousness Part of the Fabric of the Universe? | Scientific American.

Nature's Wegovy / Ozempic

The article, A Gastroenterologist Reveals How To Tap Into Your Body's Natural Processes That Inspired Ozempic explores the role of natural gut hormones and healthy food in metabolism and weight loss. It delves into how drugs like Wegovy, Ozempic, and Mounjaro, designed for weight loss and diabetes, mimic natural incretin hormones found in the gut. Specialized gut bacteria help transform undigestible components of food into molecules that regulate appetite and metabolism, emphasizing the importance of a diverse, healthy gut microbiome. These drugs reinvigorate the body's natural systems, making them effective for weight loss and blood sugar control, but lifestyle changes and whole foods are still vital for long-term health.

Snooze Control: How Your Diet Affects Your Sleep Quality

Research suggests that our dietary choices can significantly impact the quality of our sleep. Nutritional epidemiologist Erica Jansen explores the intricate relationship between diet and sleep, highlighting that adherence to nutritional guidelines, such as consuming fruits, vegetables, legumes, and whole grains, can lead to longer and better sleep—furthermore, healthier diets like the Mediterranean and anti-inflammatory are associated with improved sleep quality. While specific foods and nutrients like fatty fish, dairy, and melatonin-rich fruits play a role, the complexity of this relationship remains challenging to unravel. The article also cautions against consuming certain foods and substances that can disrupt sleep, emphasizing the importance of overall dietary patterns and good sleep hygiene practices. One Simple Change to Your Diet Could Help You Sleep Better, Study Finds.

Unleash the Joy

In A Pet Psychologist Reveals How To Give Your Dog The Best Walk of Its Life, , a pet psychologist shares valuable insights into the art of dog walking. Rather than focusing on steps, it emphasizes the importance of time spent outdoors, allowing dogs to engage in their favorite activity: sniffing. Sniffing and marking territory are crucial to a dog's experience, making it a mental exercise as much as a physical one. Rushing through walks or encouraging dogs to hurry up with their business can be detrimental, potentially leading to behavioral problems. By customizing walks to suit each dog's preferences and reframing the experience, dogs and owners can enjoy the best walks of their lives.

Awe

Here is a balanced critique and interview with the author of the book Awe: The New Science of Everyday Wonder and How It Can Transform Your Life.. I'm adding this book to my queue.

048 - Mindfulishness, Alzheimer's and the Microbiome, VR Forest Bathing - HealthHippieMD Week In Revie

Alzheimer's and the Microbiome

In a groundbreaking study, researchers have discovered that alterations in the human gut microbiome can precede the cognitive declines associated with Alzheimer's disease. The study, led by experts in the gut microbiome and Alzheimer's research, found distinct differences in the gut bacteria of individuals in the preclinical stages of Alzheimer's, even before any visible symptoms emerge. The findings raise the possibility of using stool sample analysis to detect early risk for Alzheimer's, enabling earlier interventions to slow or halt its progression. Further research aims to determine if targeted dietary changes or probiotic treatments can effectively modify the gut microbiome and delay Alzheimer's development. Changes in Human Microbiome Precede Alzheimer's Cognitive Declines

Mindfulishness: Are Meditation Apps a Distraction Trap?

In the thought-provoking article, Your Phone Is the Wrong Place to Go for Mindfulness, the author explores the paradoxical nature of meditation apps and their relationship with smartphones. While mindfulness apps offer convenient access to meditation practices and promise to bring peace of mind, they also contribute to the ever-present distraction of smartphones. The article questions the effectiveness of using these apps on a device that is notorious for causing unfocus and stress. It highlights the need for mindful choices in our phone usage and suggests that true mindfulness may lie in disconnecting from the screen altogether.

When is Anxiety a Problem?

Anxiety disorders affect approximately 1 in 5 American adults. Understanding when anxiety becomes problematic is crucial. While anxiety can serve as a protective alarm system, persistent worry and interference with daily life may signal the need for evaluation and treatment. Dr. Petros Levounis, President of the American Psychiatric Association, sheds light on recognizing anxiety's red flags and the available treatments. Notably, the article also addresses the omission of older adults from the screening recommendations and emphasizes the importance of discussing emotional concerns with healthcare providers. When Is Anxiety a Health Problem? What to Know About New Screening Guidelines - The New York Times (gift article)

Unraveling Statins

Researchers have uncovered the long-standing puzzle surrounding the muscle-related side effects of statins, America's most popular drug for managing cholesterol. While investigating the genetic causes of limb-girdle muscle dystrophy, two independent groups of scientists unexpectedly identified mutations in the gene encoding the HMG-CoA reductase enzyme—the same enzyme statins inhibit to reduce cholesterol production. The discovery sheds light on the connection between a rare genetic disease and statins' common muscle-related side effects, offering potential insights for targeted treatments and improving the lives of severely affected patients. The Gene That Explains Statins' Most Puzzling Side Effect - The Atlantic

Forest Bathing in VR

Scientists are studying whether computer-generated forests have the same effect on health and well-being that natural forests do. "Forest bathing" might work in virtual reality too | MIT Technology Review

Dark Side of the Rainbow

In Pink Floyd, 'The Wizard of Oz' and Me, (gift article) a journalist shares his connection to the phenomenon that occurs when Pink Floyd's album "The Dark Side of the Moon" is played in sync with the movie "The Wizard of Oz." The article delves into the strange and surreal coincidences that arise from this synchronization and explores the journalist's role in popularizing the concept through his early internet presence. The story reflects on the cultural impact of this unique pairing and the enduring intrigue it continues to evoke.

Virtual Tours of the NIH

Are you curious about the history and footprint of the National Institutes of Health? You can now take a virtual tour: Virtual Tour | National Institutes of Health (NIH)

Canine Clinical Trials

Dog cancer research is helping drug development for humans and canines (gift article) is about driving advancements in the development of cancer drugs for both humans and canines. Comparative oncology, the study of cancers in companion animals, offers insights into human treatments and has gained momentum due to the high failure rate of cancer clinical trials using mouse models. Studying dogs provides advantages such as shared environmental factors, cleaner data, and easier data sharing, leading to potential breakthroughs in cancer treatment for both species.

The Brain as a Prediction Engine

"For as long as we've studied human cognition, we've believed that our senses give us direct access to the world. We see what's there—or so the thinking goes. But discoveries in neuroscience and psychology have turned this assumption on its head. What if rather than perceiving reality passively, your mind actively predicts it?" I just bought the book The Experience Machine: How Our Minds Predict and Shape Reality.

Trauma Hijacks the Prediction Algorithms of the Brain

The neuroscience of trauma is an interesting video featuring Dr. Lisa Feldman Barrett, who contends that trauma alters the prediction algorithms of the brain.

Anti-Prosopagnosiacs: Human Super-Recognizers Outshine AI in Facial Recognition

Current facial recognition technology has error rates ranging from 48 to 62 percent. To address this issue, police forces in London, Berlin, and Queensland have enlisted super-recognizers help—individuals with an innate talent for recognizing unfamiliar faces. Studies show that these human experts excel in challenging scenarios where AI falls short, such as low-resolution images or crowded environments. However, racial bias remains a challenge even for super-recognizers. Researchers aim to identify exceptional talents and uncover the secrets behind their extraordinary face recognition abilities. Police Are Using Human Super-Recognizers to Replace Facial Recognition Algorithms in Some Contexts.

End the Tyranny of Processed Food

"Anyone who's struggling with [food-related disease] as an individual should take their guilt and shame and transfer it outwardly to the corporations that are feeding us these addictive substances, to the governments doing nothing about it, and to the physicians and the social media personalities who keep telling us that this stuff is healthy. We must end the conflict of interest between the industry, politicians, doctors, and scientists. Only then can we tackle the problem." An opinion piece about the role of processed food in today's society. I agree with most, except for the part about physicians conspiring. The actual problem with physicians is a lack of understanding. It's Time to End the Tyranny of Ultra-Processed Food

Aspartame to be Declared Carcinogenic by WHO

The World Health Organization will reportedly categorize Aspartame/Nutrasweet as potentially carcinogenic. Aspartame: Key ingredient in Diet Coke set to be declared 'possible cancer risk' by WHO I also learned of a study last year (in mice) where aspartame increased anxiety and fear processing across generations.Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala

043 - Brain Stimulation, Hacking Sleep, and Sad Music - HealthHippieMD Week In Review

Falling

About 25% of adults 65 and older will fall each year. Falls lead to bodily injury that speeds up the need for nursing care and, in some cases, death. Balance declines with age, but exercise can help stave off some of the risks of falling has some practical advice on how to minimize the risk for yourself and your loved ones.

Ozempic: A New Treatment for Addiction?

The weight-loss drug Ozempic, also known as semaglutide, shows unexpected side effects in patients. Along with suppressing appetite, people taking Ozempic have reported losing interest in addictive and compulsive behaviors such as drinking, smoking, shopping, nail-biting, and even skin picking. Scientists are intrigued by these anecdotes and have been studying drugs similar to liraglutide for their potential to curb addiction. The drug affects the brain's reward circuitry, making it a potential anti-addiction medication. Could Ozempic Also Be an Anti-addiction Drug?

Sad Music: Seeking Connection, Not Sorrow

A new study explores why we are drawn to sad songs, suggesting that it's not about experiencing sadness but seeking a sense of connection. While some theories propose that specific musical elements trigger sadness, the study emphasizes cognitive mechanisms and empathy as key factors. The findings indicate that people value emotional expression over technical proficiency in music and that listening to sad songs provides a connection, making us feel less alone. Why Do We Listen to Sad Songs? A New Study Offers an Answer. (gift article)

Mindfulness and Meditation

How meditation can change your life and mind explores the potential benefits of meditation and its ability to bring positive changes to people's lives. While the hype around meditation often includes extravagant claims, research suggests that mindfulness meditation, in particular, can have a significant impact. It enhances awareness and attention, improves emotional regulation, reduces stress, and fosters prosocial behaviors. However, it's important to approach meditation with an experimental mindset and find a practice that aligns with individual goals. Meditation is a valuable mental health tool but should not replace conventional care.

Peter Attia Publishes a Book

One of my favorite podcasts is Peter Attia's Drive.. He has been making the rounds promoting his new book: Outlive: The Science and Art of Longevity. The New York Times interviewed him, and I have to say, his intensity shined through: Want to Live Longer and Healthier? Peter Attia Has a Plan. (gift article)

Chronic Pain Linked to Orbitofrontal Cortex

A new, tiny study linked chronic pain to activity in the orbitofrontal cortex, an area involved in emotion regulation, self-evaluation, and decision-making. "The research suggests that such patterns of brain activity could serve as biomarkers to guide diagnosis and treatment for millions of people with shooting or burning chronic pain linked to a damaged nervous system." Although this article is intriguing, reader beware. Given the tiny sample size, it is hard to consider this finding much more than an intriguing idea. Much more research is needed. Chronic Pain Linked to Brain Signals in Orbitofrontal Cortex.

Hacking Sleep to Improve Creativity

Researchers at the MIT Media Lab and the Center for Sleep and Cognition have discovered that the first ten minutes of sleep, known as N1 sleep, can enhance creativity and problem-solving abilities. The study found that those who experienced N1 sleep and had their dreams incubated scored significantly higher in creativity tests than non-sleepers and those who only took naps. This research highlights the potential of N1 sleep for boosting creativity and finding innovative solutions. Harness the Creativity-Boosting Power of "N1" Sleep

Persistence Enhances Creativity

In the article Why We Get More Creative Over Time , the authors discuss the misconception that our creativity diminishes as we persist with a problem. Research shows that persistence is the key to generating more original ideas. Experiment participants consistently produced more creative ideas than they anticipated during subsequent attempts. The serial-order effect suggests that each successive idea will likely be better than the previous one. This pattern applies not only to individuals but also to companies and markets. The article challenges the myth of novelty and highlights the importance of persistence in achieving breakthroughs.

Ketamine vs. ECT for Depression in New England Journal

Electroconvulsive Therapy, for 80 years, has been considered the gold standard for refractory depression. Ketamine versus ECT for Nonpsychotic Treatment-Resistant Major Depression, published in New England Journal of Medicine demonstrates that ketamine may be a viable option to ECT. Ketamine Matches 'Gold Standard' in Major Depression Trial. More research is needed.

Electrifying the Mind: Rhythmic Brain Stimulation Enhances Cognitive Function

A meta-analysis suggests that tACS improves cognition in healthy, aging, and psychiatric populations is a recently published paper of over 100 studies on transcranial alternating current stimulation (tACS) reveals that rhythmically stimulating the brain with electrical currents can significantly boost cognitive function. By applying controlled currents to specific brain regions, tACS induces rhythmic brain activity, enhancing mental capabilities. The analysis suggests consistent and immediate improvements in mental function, particularly in executive function, attention, and memory. Furthermore, tACS proves effective in older adults and individuals with neuropsychiatric conditions. Rhythmically stimulating the brain with electrical currents could boost cognitive function, according to an analysis of over 100 studies.

Blood Types Ranked

Here is a quick overview of blood types and their frequency in the population: What Is the Rarest Blood Type in the World?

Conspiracy Detection Kit

Political races are heating up, and with them, various conspiracy theories. Here is a toolkit to help you determine what is real: 10 rules to tell if a conspiracy theory is true or false

041 - Doctor Dog, AI Mind-Reading, and Smelling Virtual Roses - HealthHippieMD Week In Review

Long Telomeres

"Short telomeres were thought to be bad — people with premature aging syndromes had short telomeres — so, by analogy, long telomeres were thought to be good..." A paper published last week, Familial Clonal Hematopoiesis in a Long Telomere Syndrome | NEJM, challenged current assumptions about telomere length. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds - The New York Times

Rapamycin

"Rapamycin is a paradoxical drug. It improves anti-cancer immunity, but it may also cause cancer. It protects against bacterial infection, halts viral replication, and suppresses the immune system. It reverses symptoms of Alzheimer's disease but also increases plaque deposits in the brain. It improves metabolic function, but it also causes type 2 diabetes. This list of contradictions goes on and on; however, there is one thing about Rapamycin that scientists tend to agree on: it is potentially the most powerful anti-aging drug ever discovered." I learned quite a bit from the article: Rapamycin: Unlucky history of the most powerful anti-aging drug.

ChatGPT's Empathetic Bedside Manner

In a recent study, healthcare professionals preferred the responses from A.I. over those from flesh-and-blood doctors. Could generative A.I. have a place in the future of healthcare-patient interaction? ChatGPT Has a Better 'Bedside Manner' Than Doctors.

+Quartz has some suggestions on how to get more out of your ChatGPT queries: How to use ChatGPT at work.

Futile Care

The Atlantic had an interesting opinion piece on the importance of end-of-life planning: An ICU nurse reflects on futile care. _"But what I think and feel doesn't matter. What matters is what the patient would think and whether the people who make choices about their care both know what the patient would think and understand the likelihood that their choices will have this result. This is often not the case."

Inside the Upcoming $1.5 Trillion Farm Bill

The Conversation published a peek behind the curtain as the government ramps its efforts to bring forth the next farm bill. These four challenges will shape the next farm bill – and how the U.S. eats.

The Association Between Season Allergies and Mood Disorders

"Not only are the physical symptoms draining, but a growing body of research also shows an association between allergic rhinitis — commonly known as hay fever — and mood disorders like anxiety and depression." How Seasonal Allergies Can Affect Mental Health.

Childhood Obesity

Obesity in U.S. children was already high and was exacerbated by the pandemic.Obesity in children is rising dramatically, and it comes with major – and sometimes lifelong – health consequences talks about the trend and its implications.

Mindfulness and Meditation

The benefits of mindfulness and meditation practice are numerous. The article Mindfulness, meditation, and self-compassion discusses benefits and gives practical steps to begin your practice.

Noggin Reading

Scientists have developed a mind-reading technology powered by A.I. that can decode a person's thoughts into speech. The researchers used functional magnetic resonance imaging (fMRI) and a large language model to analyze brain recordings and translate them into sentences. Although the technology's potential to help those who have lost their ability to speak, like stroke victims, is promising, it raises ethical privacy concerns. Mind-reading technology, powered by A.I., sparks ethical concerns.

Oh, Look At All the Lonely People

A recent study suggests that the brains of lonely people respond to visual stimuli in unique ways, unlike non-lonely people, implying that lonely people may view the world differently. The findings also suggest that being surrounded predominantly by people who view the world differently from oneself may be a risk factor for loneliness. The brains of lonely people process the world differently

Ode to the Human Genome Project

The Economist had an excellent article on the Human Genome Project, How the Human Genome Project revolutionized biology, although I was disappointed not to see the microbiome mentioned. As Julien Davies pointed out, the HGP is incomplete until we understand the role of microbial DNA: In a Map for Human Life, Count the Microbes, Too | Science.

Tweaking Vegetable Genes for Taste

Scientific American published an article on how CRISPR gene editing technology is being used to improve the taste of food: Tweaking Vegetables' Genes Could Make Them Tastier--And You'll Get to Try Them Soon - Scientific American (Thanks Dave Pell - NextDraft)

Doctor Dog

The article How My Dog Knows When I'm Sick is about how dogs can sense when their owners are sick and the signals they use to detect it. According to researchers, dogs can smell changes in their owners, including a virus or bacteria infection. They can also pick up on emotional changes, such as depression or lethargy, through the owner's voice changes. While it's unclear what dogs make of these changes, they may be more curious or suspicious than concerned. Nonetheless, dogs' empathy has significant benefits for human health.

Smell the (Virtual) Roses

Olfaction is tightly coupled with the parts of the brain responsible for emotions and memory. The evocative nature of the sense of smell is why companies are interested in deploying smell in the Metaverse: How to bring scents to the Metaverse and Smelling in V.R. environment possible with new gaming technology.