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055 - Forever Chemicals, Prebunking Misinformation, and Chronic Pain - HealthHippieMD Week In Review

Fiber Up

Fiber deficiency is a widespread issue, despite its numerous health benefits. Research suggests that fiber-rich diets promote healthier digestion, longer lives, and reduced risks of chronic conditions. Modern diets often fall short of recommended fiber intake, potentially due to processing that strips food of its fiber content. Experts advocate for gradually increasing fiber consumption through whole plant-based foods, such as legumes, whole grains, and fruits. These dietary adjustments can help prevent various health issues and support a well-balanced gut microbiome. Why is Fiber Good For You? And How to Eat More of It - The New York Times (gift article)

+and an article on the growing popularity of psyllium....Psyllium Husks Entice the Ozempic Generation - The New York Times

AI Transforming Music

3 ways AI is transforming music is an interesting article that mentions several sites I plan to explore.

Insurers' Unexpected Fees

As if insurers weren't making enough money, The Hidden Fee Costing Doctors Millions Every Year — ProPublicadiscusses how a powerful lobbyist's influence led to a federal agency allowing health insurers to charge fees on payments to doctors. The shift went largely unnoticed but financially impacted medical professionals. Doctors must now pay up to 5% in fees for electronic payments, creating an extra burden in an already strained healthcare system. As large insurers profit, doctors are left grappling with additional costs, potentially forcing some practices to close and increasing patient healthcare expenses.

+And more alleged shameless behavior by Cigna, one of the biggest U.S. healthcare insurers: Cigna Accused of Using AI, Not Doctors, to Deny Claims "The lawsuit says that Cigna relies on an algorithm, PxDx, to review and frequently deny medically necessary claims. According to court records, the system allows Cigna's doctors to "instantly reject claims on medical grounds without ever opening patient files." Using the system, the average claims processing time is 1.2 seconds."

Aristotle's Virtues for a Good Life

The Greek philosopher Aristotle offered a recipe for happiness, focusing not on seeking happiness but cultivating virtues to attract it. He identified ten virtues, including courage, temperance, liberality, magnificence, and more, which modern research indicates can lead to a happier life. These virtues encompass qualities like self-control, kindness, truthfulness, and forgiveness. By following this ancient wisdom and turning these virtues into habits, individuals can open the door to a life of well-being and contentment. Aristotle's 10 Rules for a Happy Life - The Atlantic

How Genes Shape Your Palate

New research has revealed 481 genome regions connected to dietary patterns and preferences for specific foods. These findings highlight the influence of genetics on our taste preferences, ranging from fruit to alcohol. Based on a large-scale genomics study, this comprehensive analysis is a significant advancement in understanding how genes impact our eating habits. The research could offer insights into nutritional needs and disease risks and guide interventions for healthier eating patterns. Your Genes May Influence What You Like to Eat - Scientific American

How to Say You're Sorry

How to Apologize Like a Pro - The Atlantic gives tips and tricks for life's inevitable disagreements and misunderstandings.

Academic M-AI-lfeasance

Academic journals struggle to spot the infiltration of generative AI in submitted papers. The use of AI to craft scholarly articles, like a recent fossil fuel efficiency study, is difficult to discern. Although some efforts have been made to enforce disclosure, many cases have slipped through. The evolving technology poses both benefits and risks. While AI can enhance non-native writers' language skills, undisclosed AI-written content could mislead, harm credibility, and even propagate AI-generated misinformation. The challenge of identifying AI-generated submissions grows as language models become more sophisticated, prompting researchers to advocate for improved detection tools and more transparent disclosure protocols. Use of AI Is Seeping Into Academic Journals—and It's Proving Difficult to Detect | WIRED

"Prebunking" Misinformation

Sander van der Linden, a University of Cambridge psychologist, pioneers a method to immunize people against fake news. Inspired by the concept of vaccines, van der Linden's approach involves exposing individuals to weakened misinformation to build cognitive defenses. His work began by countering climate change denial and evolved into collaborating with social media platforms like YouTube to display pre-video warnings about misinformation tactics. By partnering with technology giants and disseminating his ideas, van der Linden aims to empower individuals to prebunk false narratives and protect themselves against deceptive content. This Psychologist Wants To Vaccinate You Against Fake News | WIRED

Wegovy Origin Story

The article Where Ozempic, Wegovy and New Weight Loss Drugs Came From - The New York Times (gift article) explores the origin and enigmatic effectiveness of groundbreaking weight loss drugs like Ozempic and Wegovy. These medications offer hope for combating obesity, which affects a significant portion of the population. Unlike previous approaches, developing these drugs was not straightforward; researchers stumbled upon unexpected ways to induce weight loss. The drugs' mechanisms remain mysterious, exposing the brain to hormone levels never seen in nature. Despite this uncertainty, the drugs offer a new era of potential treatments for obesity.

Non-Pharmacological Approaches to Pain

The NCCIH has a page devoted to the efficacy of non-pharmacological approaches to pain relief: Chronic Pain: What You Need To Know | NCCIH

Forever Chemicals

The NY Times had an excellent (and sobering) article on "Forever chemicals: "'Forever Chemicals' Are Everywhere. What Are They Doing to Us? - The New York Times (gift article)

031 - Science / Pseudoscience of Aging, Cannabinoids and Cancer, and The World's Hottest Pepper - HealthHippieMD Week In Review

For Love of the Bean

This author loves their coffee (in reality, caffeine). "A low dose of caffeine can lead to a significant increase in … happiness and calmness and decreases in tenseness." Coffee really does make you happier

What's Your Subjective Age?

There is frequently a difference between our chronological age and our subjective age. This author examines the phenomenon: I'm 53 years old. I'm 36 in my head. - The Atlantic

The Science and Pseudoscience of Aging

Scientists are working diligently to unravel the aging process. I mentioned some of this work in 027 - Wise-Selfishness, Horvath's Clock and GrimAge - HealthHippieMD Week In Review. Here is an excellent video overview of the quest to extend our lives, including an interview with Steve Horvath: The Future with Hannah Fry And another interesting, more scientific overview of the field: Turning back time with epigenetic clocks - Nature

+More on the brave new world of chronological-age testing start-ups: How Old Are You, Really? New Tests Want to Tell You

+More on longevity research: Can We Change How Fast Humans Age? A New Study Is Getting Closer to the Answer

Periodontal Disease and Rheumatoid Arthritis

Scientists at Stanford have been working on why there is an association between poor oral health and more severe rheumatoid arthritis: Oral bacteria trigger rheumatoid arthritis flare-ups

The Last of Us

I'm enjoying the HBO series, The Last of Us. The premise that a fungus infects humans and does everything in its power to spread is borrowed from the animal world. The article, Can a Fungus Really Take Over Our Brains?, is an overview of known pathogens that alter HUMAN behavior. If you want to binge another great sci-fi/horror show, try Fortitude, supposedly one of the most scientifically accurate sci-fi shows ever made.

How to Deal with Dark Personalities at Work

Dark personalities: narcissists, psychopaths, and Machiavellians are common in society. Here is some advice on how to navigate your interactions with them at work: Here's what to do when you encounter people with 'dark personality traits' at work

A Reading List on the Neuroscience of Reading

According to the intro, humans were not designed to read. Here is a series of long-form articles on one of life's greatest pleasures: A Reading List About the Neuroscience of Reading

Digital Declutter

"Just as clutter in your home can cause stress, erode productivity, and hurt your sense of well-being, digital clutter, she said, can bring up similar feelings." Here is an interesting and helpful article from the NY Times on how to clean and organize your digital life: How to Clear Out Digital Clutter - The New York Times (gift article)

The Hottest Peppers in the World

Curious about where your favorite pepper ranks? Here you go... Hottest Pepper in the World and 6 Other Spicy Chilis

Artificial Sweetener Associated with Cardiovascular Events

This week's study in Nature Medicine, The artificial sweetener erythritol and cardiovascular event risk,, demonstrates an association between the use of erythritol and cardiovascular events such as stroke or heart attack. More research is needed. Zero-Calorie Sweetener Possibly Linked to Heart Issues, New Study Suggests (gift article)

The Microbiome and Multiple Sclerosis (pre-clinical)

These scientists are investigating how the microbiome might be manipulated as a therapeutic intervention in Multiple Sclerosis: Bile acids and gut microbes could potentially treat multiple sclerosis, according to new research in mice

Cannabinoids and Cancer

As North Carolina ponders approval of medical marijuana, these scientists are investigating how cannabinoids might be used as therapeutic agents to combat cancer: Can Cannabis Help Treat Cancer? Researchers Are Getting Closer To An Answer

GLP-1 Agonists in Economist

The Economist had a brief but informative overview of the new anti-obesity drugs. A new class of drugs for weight loss could end obesity (subscription required)

The Problem of Fraud in the Scientific Literature

The problem of fraudulent papers in medicine is much more prevalent than I believed. The Economist explains There is a worrying amount of fraud in medical research (subscription required)

Wired Guide to Quantum Computing

Wired continues its excellent series on the hottest technology topics: What Is Quantum Computing? The Complete WIRED Guide

Generative AI does Anime

Unlike the author of this article, I was fascinated by the techniques used with generative AI to make an anime from the video: Corridor Crew's AI-Generated Anime Isn't Just Callous and Craven — It's Also Dangerous Make sure to watch the linked videos in the story.

Words, Not Truths

"On the other hand, if I can talk to a bot that will give me plausible responses to things I say, it would be useful in situations where factual accuracy isn't all that important." A computer scientist chimes in on how he believes generative AI, such as ChatGPT, should be used: ChatGPT is great – you're just using it wrong

Why Some Food Tastes Better the Next Day

Here is some of the science behind why certain leftovers taste better the next day: Why certain foods taste better the next day

007- The Benign Masochism of Spicy Foods, Non-Nutritive Sweeteners, Psilocybin, and Attachment Theory - HealthHippie Week In Review - August 28, 2022

Non-nutritive Sweeteners and Weight Gain

I have been wary of artificial sweeteners for decades. A recent study in Cell, Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance , examines one potential mechanism how artificial sweeteners paradoxically cause weight GAIN, mediated through the microbiome. Sucralose and saccharine had the most harmful impact on the glycemic index (a measurement of the sugar in your blood). Read a summary article here: Non-nutritive sweeteners affect human microbiomes and can alter glycemic responses. I also found this excellent, recent overview of artificial sweeteners-especially their impact on inflammation: Artificial Sweeteners: History and New Concepts on Inflammation

Knocking Down Publisher's Paywalls

It's nice to see some real momentum in making science freely accessible. This week, the White House pushed journals to drop paywalls on publicly funded research. Naturally, the multibillion-dollar publishers are pushing back. Back in 2016, I wrote Thoughts on Open Access and Traditional Publication.. We published the manuscript I mentioned in my blog in the open access journal Frontiers in Public Health: A Novel Multiplayer Screen-Based Simulation Experience for African Learners Improved Confidence in Management of Postpartum Hemorrhage.

"Bud"wieser - Cannabis-Infused Beverages

With the rapidly expanding legalization of recreational marijuana and THC comes a bevy of products seeking to capitalize on the new trend financially. The article, Are Weed Drinks Safe? What to know About THC and Alcohol discusses the issues associated with these new products

How to Meditate when you Can't Sit Still

Meditation has many health benefits, but many people have difficulty getting a practice started. If this sounds familiar, How to Meditate When You Can't Sit Still was written for you. More information on meditation: Meditation - HealthHippieMD

Fiber, Phytonutrients, and Healthy Soil

The People's Pharmacy had an excellent discussion this week on the microbiome and regenerative farming. Show 1312: Fiber, Phytonutrients, and Healthy Soil If you're interested in regenerative agriculture, don't miss the beautiful documentary, The Biggest Little Farm.

Time-Restricted Eating / Intermittent Fasting

I found an article on intermittent fasting for weight loss, a quick overview of a subset of recent research. Does Time-Restricted Eating Help With Weight Loss?. If you're interested in this topic, Michael Greger at NutritionFacts.org has a great series of videos on the topic: Fasting For Health and Weight Loss.

+Another article on fasting (and inflammation): One form of fasting may be best to fight inflammation. In this study, individuals fasted for 24 hours once a week. People followed a regimen of "low-frequency" intermittent fasting, fasting for 24 hours once a week. The result was a higher galactin-3 in those that fasted. Galactin-3 aids in cellular repair and decreases systemic inflammation. The authors opined this regimen might have similar effects to SGLT-2 inhibitors, the newer diabetes pharmaceuticals.

"Post-Pandemic" Thoughts

Another opinion piece on the discomfort of integrating back into society without a healthy immune system: The covid pandemic has 'ended,' but I'll keep my mask on, thanks

The Benign Masochism of Spicy Foods

Quick--what animal other than humans has a preference for spicy foods? Give up? Did you have the Chinese Tree Shrew on your bingo card? Me either. An article in the Big Think covers the phenomenon of human enjoyment of spicy foods, A pleasure to burn: Why do people like spicy foods?

Neurologist's Tips for Fighting Memory Loss and Staving Off Alzheimer's

A recent Lancet commission on dementia suggested that up to 40% of Alzheimer's cases could be prevented or delayed. The article, Stop drinking, keep reading, look after your hearing: a neurologist's tips for fighting memory loss and Alzheimer's has some helpful advice, no matter your age.

Psilocybin therapy reduces heavy drinking

This week, I saw plenty of news about a manuscript published in JAMA Psychiatry, Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs. Placebo in the Treatment of Adult Patients With Alcohol Use Disorder. The article, Psilocybin therapy reduces heavy drinking by up to 83 percent in landmark trial, summarizes the study. Although the cohort was small (96 subjects), and the control group had a significant response - 51% abstaining from alcohol during the study period, the study is still quite interesting. This report will be another brick in the wall in the psychedelic industry's quest to legalize and use psychedelic compounds medically.

+An interesting article on how psychedelics and near-death experiences change core beliefs in similar ways: Psychedelic trips and near-death experiences result in strikingly similar shifts in mindset.

Attachment Style and Friendship

I read the book Attached a couple of years ago, and it left quite an impression. Unsurprisingly, attachment style influences many types of relationships, not just romantic: How Your Attachment Style Shapes Your Friendships

+What are the most valued traits we look for in friends? The most valued trait in a friend will surprise you

Embracing Idleness

Another excellent article in How to Build a Life series at the Atlantic. How to Embrace Doing Nothing, touches on the importance of leisure time. See my article, Time Poverty: a significant threat to wellness.

Quote of the Week

Knowledge is power. The real test of knowledge is not whether it is true but whether it empowers us. Scientists usually assume that no theory is 100% correct. Truth, consequently, is a poor test for knowledge. The real test is utility. A theory that enables us to do new things constitutes knowledge. - Francis Bacon


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