086 - Emotional Choreography, Musical Flow States, and Brain Waves from the Grave - HealthHippieMD Week In Review

Sweet Relief

Honey, with its long-standing reputation as a natural remedy, is being explored for its potential to alleviate hay fever symptoms. Ancient civilizations utilized honey for medicinal purposes, and today, its anti-inflammatory and anti-allergic properties are of interest. Recent research suggests that honey could act as a form of immunotherapy, desensitizing the immune system to allergens and reducing allergic reactions. Studies have shown that consuming local honey daily can lead to significant improvements in hay fever symptoms. Honey's anti-inflammatory effects, antioxidants, and prebiotic characteristics may contribute to its therapeutic potential. However, not all honey is created equal, and its efficacy can vary depending on its source and processing. While honey shows promise, it should be used alongside conventional therapies and with caution, especially in children under one and individuals with severe allergies. The Truth About Honey And Hay Fever.

Emotional Choreography

The cerebellum, traditionally known for controlling movement, is revealing its deeper role in regulating emotions, social interactions, and complex behaviors. This "little brain" at the back of our heads contains a staggering three-quarters of all brain neurons, organized in a crystalline-like structure. Recent studies, presented at the Society for Neuroscience annual meeting, challenge the long-standing view of the cerebellum's limited function. Using advanced techniques, researchers are uncovering its involvement in maternal behavior, social recognition, and even autism, suggesting it acts as a hub for sensory input and higher cognitive functions. This shift in understanding highlights the cerebellum's integral role in both movement and mental processes, showcasing its significance beyond mere physical coordination. Scientists Are Unlocking the Secrets of Your ‘Little Brain’ | WIRED.

Garden Variety

In this comprehensive guide from The Washington Post, readers are introduced to the basics of starting a vegetable garden. The article emphasizes that anyone can grow vegetables, regardless of space, by selecting the right location, sourcing quality soil, and choosing appropriate plants. It highlights the importance of sunlight, proper drainage, and understanding your hardiness zone for planting. The piece advises starting with easy-to-grow vegetables and incorporating flowers and herbs for a diverse ecosystem. It also stresses the significance of having the right attitude, embracing experimentation, and learning from failures. Overall, the article provides practical tips and encouragement for budding gardeners looking to cultivate their own edible harvest. How to start a vegetable garden - The Washington Post (gift article).

Fortune's Folly

Big Think had an excellent video on the myth of the billionaire genius."wealth is not directly correlated with brain power. Thinking smarter and working harder does not always make you rich; most of the time, it’s just about being positioned at the luckiest spot on the bell curve." Debunking the ‘billionaire = genius’ myth - Big Think.

Jazzing Up the Brain

A study conducted by Drexel University's Creativity Research Lab reveals the neural underpinnings of achieving a state of "flow" in creativity, particularly among jazz musicians in the Philadelphia area. By examining the brain activity of 32 jazz guitarists through EEG scans while they improvised, researchers found that flow is associated with reduced activity in the frontal lobes, which are responsible for executive function and cognitive control. This suggests that letting go of conscious control is key to reaching this state. The study also showed that experienced musicians were more likely to achieve flow, indicating that a foundation of expertise is necessary before one can truly "just wail," as jazz legend Charlie Parker advised. These findings not only shed light on the neural mechanisms of flow but also suggest practical strategies for enhancing creative thinking. Brain scans of Philly jazz musicians reveal secrets to reaching creative flow.

Sleep

Up to 2/3 of adults will suffer from insomnia at some point in their life. The National Center for Integrative and Complementary Health has an excellent science-based overview of various interventions: [Mind and Body Practices for Sleep Disorders: What the Science Says | NCCIH.](https://www.nccih.nih.gov/health/providers/digest/psychological-and-physical-approaches-for-sleep-disorders-science +see also Sleep Disorders – Common Types, Symptoms, Treatments | Sleep Foundation.

Brain Waves from the Grave

The new science of death: ‘There’s something happening in the brain that makes no sense’ explores the enigmatic phenomenon of heightened brain activity in individuals at the brink of death, challenging conventional understanding of the dying process. In particular, it delves into the case of "Patient One," whose brain exhibited remarkable electrical signals and connectivity even after life support was removed. This unexpected discovery, made by neurologist Jimo Borjigin and her team at the University of Michigan, suggests that the brain may enter a hyperactive state during the final moments of life, potentially giving rise to near-death experiences. The findings have profound implications for our comprehension of consciousness and the boundaries between life and death, propelling the scientific community towards new frontiers in the study of the dying brain and the possibility of reversing death itself.

Matrix of Productivity

The Eisenhower matrix, named after the 34th President of the United States, is a powerful tool for enhancing productivity by organizing tasks based on their urgency and importance. Although there's no evidence that Eisenhower himself used the matrix, its principles align with his famous saying, "What is important is seldom urgent and what is urgent is seldom important." The matrix divides tasks into four categories: do (urgent and important), decide (important but not urgent), delegate (urgent but not important), and delete (neither urgent nor important). By regularly revisiting and adjusting the matrix, individuals can maintain focus on their goals and values, ensuring that they invest their time in what truly matters. This method not only aids in managing day-to-day tasks but also helps in aligning efforts with long-term objectives, promoting a balanced and fulfilling life. Why the “Eisenhower matrix” is a fantastic productivity hack - Big Think.

A Nosh Above

Manischewitz, the 136-year-old kosher food brand, is spicing up its image with a vibrant rebrand aimed at attracting new customers and making kosher cuisine a culinary destination. The new packaging features tangerine hues, arched logos, and Hebrew-inspired accents. Shani Seidman, CMO of parent company Kayco, envisions broadening the brand's appeal beyond traditional consumers to those curious about diverse cuisines. The rebrand includes an expanded product range, from frozen matzoh balls to "Mani'z" snacks, and quirky merchandise like "Man I Shvitz" T-shirts. Despite the risks of alienating loyal customers, the move is seen as vital for the brand's long-term survival and relevance in a changing market. Manischewitz hopes its rebrand will make kosher food cool - The Washington Post (gift article).

083 - Weighty Decisions, Biting Back, and Cellular Suicide - HealthHippieMD Week In Review

Are You Doing Too Much

How can you strive for excellence without overworking yourself? Why is perfectionism on the rise? Listen to a fantastic episode of Angela Duckworth's No Stupid Questions: 184. Are You Doing Too Much? on Apple Podcasts

Bullshit Genius

In A Bullshit Genius by Oscar Schwartz, Walter Isaacson's career is scrutinized, revealing a pattern of glorifying tech moguls under the guise of neutral biographies. Once celebrated for his portrayals of historical figures like Benjamin Franklin and Albert Einstein, Isaacson shifted his focus to Silicon Valley icons, notably Steve Jobs and Elon Musk. His depiction of Jobs as a flawed yet visionary genius resonated with the public, aligning with the tech industry's self-image. However, his subsequent biography of Musk exposed the limitations of Isaacson's approach. Despite Musk's erratic behavior and questionable achievements, Isaacson attempts to fit him into the same genius narrative, ultimately failing to assess the darker aspects of Silicon Valley's influence critically. The article suggests that Isaacson's works reflect the tech industry's self-aggrandizement rather than objective analyses of true genius.

AI Coaches in the Game

The coaching industry, which focuses on professional development in critical thinking and leadership skills, is experiencing disruption from generative AI. Platforms like CoachHub are exploring AI coaching to democratize access to coaching services. Dr. Nicky Terblanche, a specialist in coaching programs, sees AI's potential in performance coaching and as a support tool for human coaches. While AI cannot yet replace human coaches in developmental coaching, it can effectively assist in structured, goal-based coaching. However, there is skepticism among coaches about AI's impact on the client-coach relationship, highlighting the need for coach education on AI benefits. Would you trust big work-life decisions to an AI coach?

Power of Prevention

"The earlier a first episode of depression begins, and the more episodes a person suffers, the more serious and disabling the condition is likely to be throughout life." Preemptive Measures highlights the importance of early intervention in preventing depression among teenagers. Esther Oladejo, an 18-year-old from Merseyside, England, shares her experience with the Blues Program, a six-week course developed by psychologist Paul Rohde to teach teens skills to manage emotions and stress. This program is part of a global movement to establish effective depression prevention strategies for young people. Research shows that early intervention can significantly reduce the onset of depression, improving life trajectories and potentially saving healthcare costs. Despite the challenges in implementing these programs widely, their success in improving mental health outcomes for at-risk teens is undeniable, as seen in Esther's story and the growing adoption of such programs in schools and communities.

The Mind's Quiet Orchestra

Your brain's "default mode" network takes the spotlight when you're not actively engaged in a task. This network, which was discovered two decades ago, comprises various brain regions that activate during restful states, offering insights into how the brain operates when not focused on external tasks. Initially thought to facilitate mind wandering or daydreaming primarily, the default mode network is now understood to play a more complex role, including memory recall, future envisioning, and self-referential thinking. This network's interactions with other brain networks, such as the salience network, are crucial in determining what to pay attention to and when to switch focus. Abnormalities in the default mode network have been explored about mental health disorders, although findings are not yet conclusive. Understanding this network and its interactions continues to challenge and refine our understanding of brain function, emphasizing the importance of internal mental activities even without overt tasks. What Your Brain Is Doing When You're Not Doing Anything | Quanta Magazine.

+see also How the Brain Creates Your Physical Sense of Self | Scientific American.

Cellular Suicide

Recent research suggests that apoptosis, a form of programmed cell death, first arose billions of years ago in bacteria. While seemingly counterintuitive, this self-destructive process is an essential and productive mechanism in complex organisms. Apoptosis can be traced back to ancient forms of cell death undertaken by single-celled organisms, which appear to have evolved as a social behavior. The origins of apoptosis might be linked to the mitochondrion, an organelle central to the process, or a long-ago interaction between our ancestors and bacteria. Studies indicate that the last common ancestor of yeast and humans already had the necessary tools for self-destruction around 2 billion years ago. This research challenges the assumption that programmed cell death is unique to multicellular organisms and suggests that it may have evolved as a way for single-celled organisms to benefit their kin or protect their colonies from disease. The discovery of bacterial genes involved in apoptosis in eukaryotic genomes points to a complex evolutionary history of this process, highlighting the interplay between survival, death, and the collective good in the natural world. Cellular Self-Destruction May Be Ancient. But Why? | Quanta Magazine.

Biting Back

Tarsus Pharmaceuticals is developing a groundbreaking pill to protect humans from Lyme disease by killing ticks before they can bite. This innovative drug, derived from the veterinary medicine lotilaner, has shown promising results in early trials, killing up to 97% of ticks within 24 hours and maintaining effectiveness for up to 30 days. The pill targets the ticks, offering potential protection against other tick-borne diseases. As Lyme disease cases continue to rise, this new form of pre-exposure prophylaxis could be a game-changer in preventing the debilitating effects of the disease. A Pill That Kills Ticks Is a Promising New Weapon Against Lyme Disease | WIRED.

Weighty Decisions

Medicare may soon cover the weight loss drug Wegovy following the FDA's approval of its use for reducing serious heart risks in obese or overweight adults. Wegovy, from the same drug class as the diabetes medication Ozempic, has shown a 20% reduction in the risk of severe heart events in clinical trials. The Centers for Medicare and Medicaid Services are reviewing the decision, with the possibility of adding Wegovy to Medicare's prescription plans. However, Novo Nordisk, the maker of Wegovy, needs help to meet the high demand for the drug, with a supply shortage ongoing since May 2023. To address this, Novo Nordisk acquired three facilities for $11 billion to increase production capacity starting from 2026. Weight loss drug Wegovy could be covered by Medicare.

Uncommon Connections

A groundbreaking study led by researchers at the National Institutes of Health has unveiled a significant link between ADHD symptoms and abnormal interactions within the brain. Analyzing over 10,000 functional brain images from youths with and without ADHD reveals enhanced connectivity between the frontal cortex and deeper brain regions responsible for learning, emotion, and behavior control. This large-scale study provides robust evidence of the neural pathways involved in ADHD, surpassing previous smaller studies. The findings not only deepen our understanding of ADHD but also open doors for developing more targeted treatments. Brain Connectivity Breakthrough Sheds New Light on ADHD - Neuroscience News (thanks, Wendy!).

081 - Mind Meld, Productive Conflict, and the Art of Saying No - HealthHippieMD Week In Review

NCCIH Relaxation Techniques

"Relaxation techniques help bring about the body's "relaxation response," characterized by slower breathing, lower blood pressure, and a reduced heart rate. The relaxation response is the opposite of the stress response." Here is an evidence fact sheet: Relaxation Techniques: What You Need To Know. | NCCIH

The Art of Saying "No" for a Happier You

In his article Overwhelmed? Just Say 'No.' - The Atlantic Arthur C. Brooks delves into the science of happiness and how saying "no" more often can lead to a more fulfilling life. He argues that the constant bombardment of demands and requests can overwhelm us and distract us from our happiness. Brooks identifies two main issues that contribute to this problem: hyperbolic discounting, which leads us to prioritize immediate pleasures over future benefits, and the fear of future regret, which can make us hesitant to decline opportunities. He suggests three strategies to combat these tendencies: forming a "No Club" for accountability, making "no" the default response, and adding friction to the process of saying "yes." By mastering the art of saying "no," Brooks believes we can focus more on our priorities and lead happier lives.

Long-Covid's Foggy Forecast

A comprehensive study in England involving nearly 113,000 participants has revealed that individuals with persistent post-COVID symptoms, commonly referred to as long-term COVID-19, exhibit a measurable decline in cognitive abilities, particularly in memory, reasoning, and planning. The study, published in The New England Journal of Medicine, found that those with long Covid scored the equivalent of 6 I.Q. points lower than those who had never been infected. Even individuals who had recovered from Covid-19 showed a slight decline in cognitive performance compared to the uninfected. However, the study also offers hope, suggesting that the associated cognitive impairment might improve if Covid symptoms ease over time. This research provides numerical evidence for the cognitive challenges many long Covid sufferers face and highlights the importance of understanding and addressing the long-term effects of the virus on mental function. Long Covid May Lead to Measurable Cognitive Decline, Study Finds - The New York Times (gift article).

Covid is NOT the Flu

Four years into the COVID-19 pandemic, the United States' approach to managing the virus increasingly resembles its handling of seasonal flu. Vaccines are updated annually, and the CDC is considering more flu-like isolation guidelines. Despite some similarities, COVID-19 and flu are distinct, with COVID-19 causing more hospitalizations and deaths and having a less predictable pattern. The trend towards treating COVID-19 as a routine illness raises concerns about diminishing precautions and the potential underutilization of treatments like Paxlovid. This shift may also obscure the ongoing impact of long COVID and reduce incentives for testing. While some policy convergence is understandable, experts worry that the U.S. is moving too quickly towards normalizing COVID-19 without adequately addressing its unique challenges. Why Are We Still Flu-ifying COVID? - The Atlantic.

Productive Conflict

"The goal. It isn't to avoid conflict. At the highest level, it's to recognize what kind of conversation you're having." Derek Thompson explores the insights from Charles Duhigg's book, "Supercommunicators," on improving communication in relationships. The article highlights the importance of recognizing the type of conversation, whether practical or emotional, to avoid unnecessary conflicts. It also delves into research from the 1970s by psychologists known as the "Love Shrinks," who studied how married couples navigate conflicts. Their findings revealed that all couples fight, but the key to a healthy relationship is not what they fight about but how they fight. Happy couples tend to focus on controlling themselves rather than their partners, avoid escalating the conflict, and use "I" statements instead of accusatory "you" statements. Thompson shares his realization of the importance of staying on topic during arguments, using the metaphor of not "opening new tabs" in a browser. The article suggests asking three brief questions during conflicts to improve communication: "Are we opening new tabs?" "Are we venting or problem-solving?" and "What if I tried to control only myself?" Three Ways to Have Better Fights - The Atlantic

The Neuroscience of Hanging Art

Arranging art on walls can be overwhelming, but incorporating whimsy and proportion can enhance enjoyment. Neuroscience suggests considering the viewer's perspective, with art ideally hung 56 to 60 inches above the floor. For groupings, prioritize special pieces, maintain spacing, and consider symmetry, which is psychologically pleasing. Planning layouts on the floor before hanging can ensure a satisfying arrangement. The article emphasizes that while there are guidelines, personal expression and creativity are key to a visually appealing display. How to hang art and photos to please the eye and the brain - The Washington Post (gift article).

Mind Meld

The Remarkable Ways Our Brains Slip Into Synchrony | The MIT Press Reader explores the fascinating ways in which our brains synchronize during shared experiences, a phenomenon increasingly supported by cognitive science research. This synchronization is evident in various scenarios, such as collaborating on a task, engaging in conversation, or sharing a meal. The merging of individual cognitions creates a fluid exchange of information, blurring the lines between separate entities. Experiments have shown that when people work together, their actions and even postural sways can become coordinated, resembling the behavior of a single system. This coordination extends to brain activity, eye movements, and gestures, enhancing empathy and rapport. The article highlights that effective communication is about exchanging messages and co-creating a shared experience, underscoring the deep interconnectedness of human cognition. (Thanks, Wendy)

Microbiome and Retinal Disease

Recent research suggests a surprising link between gut bacteria and inherited retinal diseases like retinitis pigmentosa, which can lead to blindness. The study, published in Cell, challenges the long-held belief that the eyes are shielded from bacterial invasion. Researchers found that mutations in the CRB1 gene, a leading cause of these diseases, weaken the protective barrier around the eye and the cell linkages in the colon, allowing gut bacteria to travel to the retina. Experiments with Crb1-mutant mice showed that depleting gut bacteria or treating with antibiotics reduced retinal damage, hinting at potential new treatments. However, experts urge caution, as the complexity of the disease and the role of bacteria are not fully understood, and antibiotics may not reverse the genetic damage. The surprising link between gut bacteria and devastating eye diseases. (Thanks, Amy)

080 - Entrepreneurial Hearts, Microbial Moodiness, and an Ode to Pop-Tarts - HealthHippieMD Week In Review

I increased the number of articles today since I won't publish a newsletter next week. The newsletter will return on March 3, 2024.

Tidying Up for Sanity

"The average person likely loses 5 percent of their time due to disorganization. Take your annual salary, multiply that by 5 percent, and you can measure what disorganization may be costing you." In Being organized can improve mental health. This is why., Daryl Austin explores how organization can positively impact mental health. Research suggests that living in a cluttered environment is associated with memory issues, poor eating habits, mood disorders, and decreased impulse control. It also is associated with increased stress levels, affecting overall well-being. However, organizing can enhance productivity, reduce exhaustion, and improve quality of life. Experts recommend starting small, setting aside specific time for decluttering, and enlisting support if needed. Digital decluttering is also emphasized. Ultimately, organizing sends a message of self-worth and can lead to a more intentional and loving relationship with one's home.

Aging Gracefully

As life expectancy increases, researchers are shifting focus from merely extending lifespan to enhancing healthspan—the years free from debilitating diseases. Key strategies include studying centenarians for genetic insights, promoting healthy lifestyles through diet, exercise, and mental engagement, and exploring experimental medications like metformin and rapamycin. Self-monitoring and social connectivity also play pivotal roles. While the quest for longevity continues, experts stress the importance of prevention and personalized approaches to optimize healthspan and ensure a healthier, more fulfilling life as we age.It's not your life span you need to worry about. It's your health span.

Long COVID's Exercise Paradox

A recent study sheds light on why many long COVID sufferers struggle with exercise. Post-exertional malaise (PEM), a defining symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), leads to a debilitating cycle of fatigue and worsened condition in Long-COVID patients. The study reveals that after exercise, these patients experience muscle damage, changes in muscle composition, and disrupted energy metabolism. Notably, they exhibit lower energy-generating processes and an impaired ability to recover from exercise. These findings underscore the importance of pacing oneself to minimize the severity and duration of post-exertional malaise in long COVID patients. Long COVID can destroy your ability to exercise. Now we know why.

Wired for Sound

Exploring the neuroscience of musical preference reveals intriguing connections to our personalities, emotions, and social identities. Our brains are naturally drawn to music with unexpected elements, triggering pleasurable responses. Studies show that our musical tastes evolve, influenced by our emotions and experiences. This suggests a deep link between music preference and personal identity. Understanding these connections can help bridge gaps between individuals with different tastes, highlighting musical enjoyment's universal and individual aspects. The Neuroscience of Musical Tastes - Neuroscience News.

Mastering the Apology

Why is it so challenging to deliver a genuine apology? Experts say a sincere apology requires vulnerability and humility, admitting wrongdoing without justifications or excuses. Research shows that effective apologies can lead to forgiveness, benefiting both the giver and the receiver. To craft a meaningful apology, experts suggest expressing regret without using conditional language, explaining the offense briefly, acknowledging the harm caused, promising not to repeat the mistake, offering to make amends, and gently requesting forgiveness. These steps can help repair relationships and foster understanding. How to Apologize Like You Mean It - The New York Times (gift article).

Self-Training Paradox: AI's Strange Evolution

As AI evolves, researchers turn to self-training methods, using machines to teach machines. This approach, while promising, raises concerns about the technology's opacity and potential to produce "unintelligible intelligence." With AI models already exhibiting complex behaviors and the ability to "cheat" in tasks, the path to actual artificial teaching is fraught with challenges. While self-training could lead to groundbreaking discoveries and efficiencies, it also poses risks of reinforcing biases and producing outcomes humans struggle to understand or control. As AI advances, so does the need to consider its capabilities and implications carefully. Things Get Strange When AI Starts Training Itself - The Atlantic.

Ageless Wonders

From the depths of the oceans to the ancient lands, Earth's inhabitants boast lifespans that defy human comprehension. Bowhead whales roaming Arctic waters can live over 200 years, while Jonathan, the Seychelles giant tortoise, has thrived for over 190 years. By unlocking the secrets of these long-lived creatures, scientists aim to understand the complex interplay of genetics, environment, and lifestyle that contributes to their exceptional lifespans. What Is the Longest Living Animal? From Tortoises to Whales | HowStuffWorks.

Memory Meltdown

A night of less than six hours of sleep can significantly impact your short-term memory, impairing your ability to recall information the next day. Sleep-deprived individuals may also experience reduced attention, emotional instability, and difficulty encoding new information. Lack of sufficient sleep can negatively affect the brain's frontal lobe, impacting memory retrieval and executive function. While remote memories remain intact, short-term memory and cognitive performance decline with each additional hour of missed sleep. Proper rest is crucial for memory consolidation and overall cognitive health. How Sleep Deprivation Can Affect Memory - The New York Times (gift article).

An Ode to Pop-Tarts

The passing of Bill Post, one of the creators of Pop-Tarts, stirs memories of this iconic childhood treat. Originally released in Cleveland 60 years ago, Pop-Tarts have become a pop-culture phenomenon, evolving into various forms and flavors. From the classic Frosted Pop-Tarts to the quirky Ted's Tarts knockoffs, these toaster pastries have captured hearts and taste buds. Comedians like Jerry Seinfeld have even immortalized them in routines. As we remember Post's legacy, we also celebrate the enduring appeal of these sweet treats that symbolize American nostalgia (and ultra-processed food). A toast to Pop-Tarts, the childhood treat I couldn't resist - The Washington Post (gift article).

Mood Mice-robials

Recent research has shown that the bacteria in your gut, particularly strains of Lactobacillus, can significantly influence mood and stress resilience. Studies on mice have revealed that specific bacterial strains can reduce stress and anxiety-like behavior, suggesting a direct link between the gut microbiome and mental health. This research opens new avenues for developing probiotics that target mood regulation, highlighting the importance of a healthy, probiotic-rich diet for mental well-being. Bacteria in your gut can improve your mood − new research in mice tries to zero in on the crucial strains.

Funny Bone-obos

Research conducted by Erica Cartmill and her colleagues reveals that great apes, including chimpanzees, bonobos, orangutans, and gorillas, engage in playful teasing behaviors resembling humor's building blocks. These actions, which include prodding, tickling, and stealing, are believed to have evolved over 13 million years ago and may serve to strengthen social bonds and provide insight into the tolerance levels of their peers. The study, which analyzed 75 hours of footage from two zoos, suggests that these behaviors demonstrate social intelligence and foresight, as successful teasing requires understanding others' psychological boundaries. This research sheds light on the early precursors of joking and the complex social dynamics within great ape communities. Great Apes Possess the Building Blocks of Humor - The Atlantic.

The Entrepreneurial Heart

In an article by Arthur Brooks for The Atlantic, the author parallels romantic love and entrepreneurship, suggesting that both ventures require a healthy attitude towards failure for ultimate success. Brooks argues that just as aspiring entrepreneurs must be prepared for the likelihood of failure, individuals seeking love must also embrace the possibility of heartbreak. He suggests that, much like failed business ventures, failed romances offer valuable lessons that can lead to greater happiness in future relationships. The article emphasizes the importance of learning from romantic failures, avoiding the "doom loop" of repeated mistakes, and maintaining a positive outlook on love despite setbacks. By adopting an entrepreneurial mindset, individuals can increase their chances of finding true romance.What to Do If the Course of True Love Is Not Running Smoothly - The Atlantic.

035 - Dumb Questions, Gallows Humor, and Synesthesia - HealthHippieMD Week In Review

In Pursuit of the Perfect Shot of Espresso

Understanding Espresso: A Six-Part Series Explaining What It Takes to Pull the Ideal Shot includes videos on "how to choose the right dose of coffee, ratio between the amount of ground and liquid coffee, brew time, grind size, brew temperature, and pressure."

The Wisdom of Dumb Questions

"Can you explain this to me like I barely know anything about this subject?" Asking "dumb" questions is an effective way to bring out the knowledge of experts: Stop Trying to Ask 'Smart Questions'

Exercise May Counteract the Negative Effects of Too Little Sleep

"a new study suggests that exercise could potentially help counteract the health consequences of not getting a proper amount of sleep." Exercise May Help Counteract the Toll of Poor Sleep, Study Suggests(gift article)

The Science of Habits

Are you trying to develop a good habit or break a bad one? Here are some science-backed tips to help: The science of habits. See also Atomic Habits: An Easy & Proven Way to Build Good Habits & Break Bad Ones.

Bad Actors of Health Insurance

Here's an article from ProPublica on how commercial health insurers automatically deny claims and how Cigna developed an incentive system that encourages the behavior. How Cigna Saves Millions by Having Its Doctors Reject Claims Without Reading Them

The Strange Benefits of Gallows Humor

"The most surprising result is that subjects which show the highest values with respect to black humor preference … show the lowest values regarding mood disturbance and aggression." Gallows humor: The surprising benefits of dark laughter

Cockroaches Diminishing Sweet-Tooth

Here is an interesting article about the cat-and-mouse game of cockroaches and human endeavors to eliminate them: Cockroaches have outsmarted us again

Aging and Microgravity

Microgravitational environments have all sorts of effects on the body. These scientists are trying to unravel the impact of space travel on aging: New Study Suggests One Aspect of Space Travel Can Accelerate Aging

Science-Backed Approaches to Depression

The incidence of depression increased during the pandemic. Here are some science-backed tips for combatting the blues: These Science-Backed Strategies Can Help "Hard to Treat" Depression

Measuring Fitness Minimizing Attention to Weight

Here are some factors to focus on instead of the scale: How Fit Are You? 3 Ways to Measure Without Focusing on Weight - The New York Times

Multiple Sclerosis: What the Science says about Complementary Approaches

The National Center for Complementary and Integrative Health published a great resource : Multiple Sclerosis and Complementary Health Approaches: What the Science Says

Friendship Recession

Americans without friends have increased by 250% in recent years. Lacking friends is as bad as smoking more than a dozen cigarettes daily. BigThink tackles the phenomenon: The friendship recession - Big Think

A Doctor's Experience with Ozempic

I read an interesting article by a physician who hopped on the glucagon-like peptide 1 (GLP-1) receptor agonist train--the weight loss drug taking the world by storm: What's It Like to Take Ozempic? A Doctor's Own Story

American Heart Association's Life's Essential 8

The AMA published a study looking at eight lifestyle factors and their association with life expectancy and chronic disease: Life's Essential 8: Higher Scores Extend Health Span

Ultra-processed Food and Cancer Risk

"A new analysis suggests that replacing even a small amount of ultra-processed foods with an equal amount of minimally processed options may reduce certain cancer risks." Ultraprocessed Foods and Cancer: Small Changes May Lower Risk

The Power of Walking

The NY Times had an ode to walking: Opinion | Whatever the Problem, It's Probably Solved by Walking (gift article)

How to Tell If Your Brain Needs a Break

We all suffer from brain slumps that impact our ability to do quality work. This is what to do when you're in one: How a Brain Break Can Increase Focus and Productivity

Synesthesia

What do Billy Joel, Billie Eilish, and Vincent van Gogh have in common?-They all experience(d) music in colors. Big Think explores the phenomenon of synesthesia: Billie Eilish, van Gogh, and the trippy science of synesthesia

031 - Science / Pseudoscience of Aging, Cannabinoids and Cancer, and The World's Hottest Pepper - HealthHippieMD Week In Review

For Love of the Bean

This author loves their coffee (in reality, caffeine). "A low dose of caffeine can lead to a significant increase in … happiness and calmness and decreases in tenseness." Coffee really does make you happier

What's Your Subjective Age?

There is frequently a difference between our chronological age and our subjective age. This author examines the phenomenon: I'm 53 years old. I'm 36 in my head. - The Atlantic

The Science and Pseudoscience of Aging

Scientists are working diligently to unravel the aging process. I mentioned some of this work in 027 - Wise-Selfishness, Horvath's Clock and GrimAge - HealthHippieMD Week In Review. Here is an excellent video overview of the quest to extend our lives, including an interview with Steve Horvath: The Future with Hannah Fry And another interesting, more scientific overview of the field: Turning back time with epigenetic clocks - Nature

+More on the brave new world of chronological-age testing start-ups: How Old Are You, Really? New Tests Want to Tell You

+More on longevity research: Can We Change How Fast Humans Age? A New Study Is Getting Closer to the Answer

Periodontal Disease and Rheumatoid Arthritis

Scientists at Stanford have been working on why there is an association between poor oral health and more severe rheumatoid arthritis: Oral bacteria trigger rheumatoid arthritis flare-ups

The Last of Us

I'm enjoying the HBO series, The Last of Us. The premise that a fungus infects humans and does everything in its power to spread is borrowed from the animal world. The article, Can a Fungus Really Take Over Our Brains?, is an overview of known pathogens that alter HUMAN behavior. If you want to binge another great sci-fi/horror show, try Fortitude, supposedly one of the most scientifically accurate sci-fi shows ever made.

How to Deal with Dark Personalities at Work

Dark personalities: narcissists, psychopaths, and Machiavellians are common in society. Here is some advice on how to navigate your interactions with them at work: Here's what to do when you encounter people with 'dark personality traits' at work

A Reading List on the Neuroscience of Reading

According to the intro, humans were not designed to read. Here is a series of long-form articles on one of life's greatest pleasures: A Reading List About the Neuroscience of Reading

Digital Declutter

"Just as clutter in your home can cause stress, erode productivity, and hurt your sense of well-being, digital clutter, she said, can bring up similar feelings." Here is an interesting and helpful article from the NY Times on how to clean and organize your digital life: How to Clear Out Digital Clutter - The New York Times (gift article)

The Hottest Peppers in the World

Curious about where your favorite pepper ranks? Here you go... Hottest Pepper in the World and 6 Other Spicy Chilis

Artificial Sweetener Associated with Cardiovascular Events

This week's study in Nature Medicine, The artificial sweetener erythritol and cardiovascular event risk,, demonstrates an association between the use of erythritol and cardiovascular events such as stroke or heart attack. More research is needed. Zero-Calorie Sweetener Possibly Linked to Heart Issues, New Study Suggests (gift article)

The Microbiome and Multiple Sclerosis (pre-clinical)

These scientists are investigating how the microbiome might be manipulated as a therapeutic intervention in Multiple Sclerosis: Bile acids and gut microbes could potentially treat multiple sclerosis, according to new research in mice

Cannabinoids and Cancer

As North Carolina ponders approval of medical marijuana, these scientists are investigating how cannabinoids might be used as therapeutic agents to combat cancer: Can Cannabis Help Treat Cancer? Researchers Are Getting Closer To An Answer

GLP-1 Agonists in Economist

The Economist had a brief but informative overview of the new anti-obesity drugs. A new class of drugs for weight loss could end obesity (subscription required)

The Problem of Fraud in the Scientific Literature

The problem of fraudulent papers in medicine is much more prevalent than I believed. The Economist explains There is a worrying amount of fraud in medical research (subscription required)

Wired Guide to Quantum Computing

Wired continues its excellent series on the hottest technology topics: What Is Quantum Computing? The Complete WIRED Guide

Generative AI does Anime

Unlike the author of this article, I was fascinated by the techniques used with generative AI to make an anime from the video: Corridor Crew's AI-Generated Anime Isn't Just Callous and Craven — It's Also Dangerous Make sure to watch the linked videos in the story.

Words, Not Truths

"On the other hand, if I can talk to a bot that will give me plausible responses to things I say, it would be useful in situations where factual accuracy isn't all that important." A computer scientist chimes in on how he believes generative AI, such as ChatGPT, should be used: ChatGPT is great – you're just using it wrong

Why Some Food Tastes Better the Next Day

Here is some of the science behind why certain leftovers taste better the next day: Why certain foods taste better the next day

025 - Chronobiology, Anticipation, Cancer Dietary Choices - HealthHippieMD Week In Review

One Question to Boost Your Longevity and Well-being

Having something to look forward to has many health benefits: Asking yourself one fun question could help boost your well-being and longevity.

A Simple Dietary Swap to Improve Health

The new year is a time to examine our habits. If you've resolved to improve your diet, here is a simple yet effective way to improve the quality of your food: For weight loss, replace processed foods with healthy, fiber-rich carbs. (gift article)

Chrononutrition

Another article from WaPo on why you should front-load your calories early in the day: Why timing big meals early in the day is better for your health. (gift article)

Chronobiology and Chronotherapy

Scientists are slowly learning the importance of timing of oral medications: Timing matters for medications – your circadian rhythm influences how well treatments work and how much they might harm you. Yet, the FDA recognizes the importance of timing in only a few medications: Dosing time matters | Science.

New Study Demonstrates Association between Healthy Eating and Reduced Mortality

JAMA published a study demonstrating the association between healthy eating and decreased mortality this week. Although the investigation suffers from the traditional caveats of nutrition research (food diaries, etc.), it differentiates itself by the size of the cohort and the length of follow-up (36 years). Healthy Eating Patterns and Risk of Total and Cause-Specific Mortality.

The Psychology of Procrastination

If one of your resolutions is to procrastinate less, here is an article to help you understand how to overcome inertia: What causes your brain to procrastinate and how to face it. (gift article). One of my favorite internet sites, Wait but Why, also has a series on procrastination:

• Why Procrastinators Procrastinate — Wait But Why
• How to Beat Procrastination — Wait But Why
• The Procrastination Matrix — Wait But Why^a26c07

ZOE Nutrition

Tim Spector founded a personalized nutrition company and wants you to know why: Go with your gut: scientist Tim Spector on why food is not just fuel. The test is a bit expensive but is likely a harbinger of nutritional trends to come.

The Daily Habits of Happiness Experts

The people that study happiness have some valuable habits we can all learn from The Daily Habits of Happiness Experts.

England Bans Single-Use Cutlery

In an attempt to reduce pollution, England has banned single-use items such as plastic cutlery, plates, and trays. England Will Ban Single-Use Cutlery and Plates.

Scientific Stagnation

This year, a new study, Papers and patents are becoming less disruptive over time, reported any given paper today is much less likely to become influential than a paper in the same field from several decades ago. Science Has a Crummy-Paper Problem - The Atlantic

Hearing Aids and Cognition

Restoring hearing was linked with less long-term cognitive decline, a recent systematic review and meta-analysis showed: Use It, or Lose It: Hearing Aids Linked to Cognitive Benefit.

Cancer and Diet

Michael Greger has a great series of videos on food and cancer. In the latest, he offers his thoughts on what you should (and shouldn't) eat if you've already been diagnosed with cancer: The Best Diet for Cancer Patients.

How Music Casts its Spell on Us

Another excerpt from the book, Awe: The New Science of Everyday Wonder and How It Can Transform Your Life. The article The Neurophysiology of Enchantment: How Music Casts Its Spell on Us, discusses the neurophysiology of music appreciation. +Jeff Beck, one of the greatest guitarists of all time, passed away this week. The NY Times published a list of his ten essential songs: Jeff Beck's 10 Essential Songs (gift article)

Covid and the Immunocompromised

Although most Americans seem done with Covid and Covid precautions, the risk is still high for those of us that are immunocompromised. Here is an opinion piece on how society could protect its vulnerable citizens: Opinion | We need to do more to assist the immunocompromised. (gift article)