Burnout

087 - Gut Fungi, Green Acres, and Counting Sheep - HealthHippieMD Week In Review

Burning the Midnight Oil

A recent study underscores the alarming effects of working late shifts and variable schedules in young adulthood. The research, spanning three decades and including over 7,000 Americans, reveals that those with volatile work schedules, including night hours and rotating shifts, are more likely to experience poor health and depression at age 50. These findings illuminate the severity of burnout culture, where work demands often surpass the body's capacity, leading to long-term health implications. The study underscores the urgent need for support systems to help individuals maintain a healthy work-life balance and mitigate the risks associated with overwork. Burnout culture: Working late shifts can lead to depression poor health. Burnout culture: Working late shifts can lead to depression, poor health : Shots - Health News : NPR.

The Sound of Silence in Live Music

 Is a love of live music wrecking your hearing? Don't let it. - Washington Post (gift article) discusses the potential harm that loud live music can cause to our hearing. Drawing from personal experience and expertise, the author highlights the dangers of prolonged exposure to high decibel levels, even in seemingly innocuous settings like bars and restaurants. The article provides practical measures for protecting one's hearing, such as using earplugs and limiting exposure time, while advocating for increased awareness and responsible practices in live music venues. Opinion | Is a love of live music wrecking your hearing? Don’t let it. - Washington Post.

Green Acres, Strong Minds

According to research, spending time in green spaces like parks can significantly improve physical and mental health. Studies show that regular exposure to nature can lower blood pressure, strengthen the immune system, reduce the risk of cardiovascular disease, and improve sleep quality. Moreover, it is associated with reduced depressive symptoms, stress alleviation, and improved cognitive function. However, access to green spaces is unequal, with lower-income communities having less access to parks and trees. Scientists are using innovative methods, such as machine learning and satellite imagery, to measure the impact of greenery on health outcomes, aiming to address health disparities. Walks in Green Parks Mean Stronger Immune Systems and Better Mental Health | Scientific American (paywall).

Counting Sheep

A recent Gallup poll reveals a concerning trend: a majority of American adults are experiencing insufficient sleep, a first in the survey's history. This lack of rest is closely tied to increased stress levels, with many individuals reporting feeling frequently stressed. The situation has worsened over the years, with more people now feeling the effects of sleep deprivation. Women, especially those under 50, are disproportionately affected compared to men. The connection between poor sleep and stress is bidirectional, underscoring the need for strategies to improve sleep quality and reduce stress levels, particularly among younger Americans. Americans aren't sleeping enough, Gallup poll says. Americans aren't sleeping enough, Gallup poll says.

Unveiling the Brain's Symphony

Scientific American had an article about a study that reveals that the brain's cortex operates like a symphony, with each layer specializing in generating different brain waves. The study, conducted across 14 cortical regions and four species, shows that outer layers process sensory input while deeper layers control how the brain processes that information. This discovery could have significant implications for understanding and treating neuropsychiatric disorders. By identifying the specific brain layers involved in generating different waves, researchers hope to shed light on conditions such as schizophrenia, where imbalances in brain waves are evident. Scientists Discover Extensive Brain-Wave Patterns | Scientific American (paywall).

Mouth Microbe May Muddle with Colon Cancer

Researchers have uncovered a potential link between colon cancer and a bacterium commonly found in the human mouth. The study identified a specific subtype of Fusobacterium nucleatum that appears to be associated with colon cancer growth and progression. This discovery could lead to improved screening methods and new therapies for the disease. The bacteria's presence in colon tumors suggests a connection to disease development, highlighting the need for further research. The findings may pave the way for a vaccine targeting this bacterium, similar to the approach used for the human papillomavirus. Colon Cancer Linked to Mouth Bacteria | Scientific American (paywall)(thanks, Amy).

How Gut Fungi Worsen Covid

In a study published in Nature Immunology, researchers discovered that severe COVID-19 patients exhibit an imbalance of certain gut fungi, triggering a prolonged immune response that outlasts the initial infection. This imbalance leads to increased neutrophils, causing inflammation characteristic of Covid-19. The study highlights the intricate relationship between the gut microbiome and the immune system, suggesting the potential for personalized medicine in treating COVID-19 patients with antifungal drugs. The findings also raise questions about the long-term effects of fungal overgrowth in COVID-19 recovery and the potential for future fungal infections. Unruly Gut Fungi Can Make Your Covid Worse | WIRED.

A Dietary Puzzle for I.B.S. Relief

A new study suggests dietary changes trump medication to tame irritable bowel syndrome (I.B.S.). I.B.S., afflicting an estimated 6% of Americans, presents chronic abdominal pain, bloating, diarrhea, and constipation. Though its cause remains elusive and no cure exists, managing symptoms through diet adjustments or medication helps. The study, featured in The Lancet Gastroenterology and Hepatology, reveals promising clues. Notably, in most cases, a low-FODMAP diet—avoiding certain foods like wheat, legumes, and dairy—has shown symptom reduction. This discovery offers hope for those grappling with the complexities of I.B.S. What's the Best Way to Treat I.B.S.? - The New York Times (gift article).

065 - Opposites Don't Attract, Black Licorice, and Cognitive Reserves - HealthHippieMD Week In Review

Association Between Red Meat Intake and Type 2 Diabetes Risk

A comprehensive study recently published in The American Journal of Clinical Nutrition has identified an association between the frequency of red meat consumption and an increased likelihood of Type 2 diabetes development. "After adjusting for other factors, including physical activity and alcohol intake, the researchers found that the more servings of red meat that people ate, the more likely they were to develop diabetes." The research, which encompassed the analysis of dietary patterns and medical records of approximately 217,000 health professionals, particularly highlighted a heightened risk associated with processed meats, including bacon, hot dogs, and lunch meats. While the study delineates correlation rather than causation, it suggests that dietary modifications, such as reducing red meat consumption and emphasizing plant-based proteins, could decrease the associated risks. Eating Red Meat May Increase Type 2 Diabetes Risk, Study Suggests - The New York Times. (gift article)

A.I.'s Fresh Perspective on Food Preservation

Rancidity, the unsavory side effect of oxidation, challenges food quality and safety. Researchers have traditionally relied on antioxidants to counteract this, but determining the right mix can be complex and time-consuming. Enter artificial intelligence. Scientists have harnessed A.I. to predict the optimal combinations of antioxidants, offering a more precise approach to food preservation. While initial results showed discrepancies between A.I. predictions and lab tests—especially with lard—continued data input fine-tuned the model's accuracy. With AI's predictive prowess, the future of food preservation may see enhanced efficiency and broader applications. Can A.I. Help Stave Off Food's Expiration? - The Atlantic.

Déjà Vu: A Glimpse into Memory's Mysteries

Déjà vu, that uncanny feeling of having "been here before" has puzzled humanity for ages. Anne Cleary delves deep into this phenomenon, suggesting it's more than a quirky brain glitch. Historically, explanations have varied from mere double perception to complex memory-based theories. Recent research from Cleary's lab proposes that déjà vu might be an evolutionary tool, sharpening our attention for survival. Interestingly, around two-thirds of people experience déjà vu, often triggered by familiar settings. While the sensation remains enigmatic, Cleary's exploration suggests a blend of memory, perception, and, perhaps, a touch of irony from our brains. Déjà vu – a window on the past and a key to human survival | Aeon Essays.

Personalized Nutrition: The Government Wants You!

The U.S. federal government has initiated a comprehensive study to delve deeper into personalized nutrition. While established dietary guidelines offer a general roadmap for health, individual responses to food can vary due to genetics, gut microbiomes, and other factors. The National Institutes of Health, with a budget of $189 million, is set to recruit 10,000 adults over five years. This study, titled "Nutrition for Precision Health," aims to understand how individuals metabolize and react to different diets. The ultimate goal is to utilize this data to create machine-learning algorithms for bespoke diet plans, moving beyond the conventional one-size-fits-all approach. What's the best diet? A federal study aims to find out. - The Washington Post. (gift article) ^

The Mediterranean Diet

The New York Times, back in January, published a great article on the Mediterranean Diet: The Mediterranean Diet Really Is That Good for You. Here's Why. - The New York Times (gift article)

Healthcare Workers and Burnout

The C.D.C. published a new study on the American Workforce. They found that healthcare workers were disproportionately burned out compared to other professions surveyed. "Prior to Covid, we knew that many hospitals were understaffed, that health care workers were burning out," Dr. Debra Houry, the chief medical officer at the C.D.C., said in an interview on Tuesday. "I think Covid escalated that, and I think it just really strained the system." Why Health Care Workers Are Burning Out - The New York Times. (gift article)

The Unspoken Privacy Revelations of A.I.

Recent research has unveiled that advanced chatbots can discern significant personal information from seemingly innocuous conversations. These chatbots, trained on vast amounts of web content, are adept at identifying subtle linguistic patterns, enabling them to accurately infer details such as a user's race, location, and occupation. This capability raises concerns about user privacy and hints at a potential shift in advertising strategies, where chatbots could be used to construct detailed user profiles. As technology advances, the line between anonymity and transparency becomes increasingly blurred. A.I. Chatbots Can Guess Your Personal Information From What You Type | WIRED.

Introverts Guide to Extroversion

Laurie Santos's Podcast this season focuses on social connection. This week, I listened to The Introvert's Guide to Extroversion. As a card-carrying introvert, I found many of the suggestions helpful (and a bit terrifying).

Busting the Opposite Attract Myth

A recent large meta-analysis in Nature Human Behavior blows up the myth that in relationships, opposites attract. In fact, "like attracts like." "Opposites attract" is a myth. Partners often share traits - Big Think.

Brain Bank

We may finally know how cognitive reserve protects against Alzheimer's explores the concept of cognitive reserve and how it can help protect our thinking abilities as we age. It discusses the latest research on the mechanisms behind cognitive reserve and how education, lifestyle, and social engagement can all contribute to building mental reserves. The file also includes a retirement quiz and other helpful resources to help plan for a comfortable future. Overall, it emphasizes the importance of exercising the brain throughout life and taking steps to maintain cognitive health. (requires Apple News+ Subscription)

American Friendships by the Numbers

A recent study by the Pew Research Center provides an in-depth analysis of friendship patterns in the U.S. The research reveals diverse friendship circles, encompassing members from hobby groups to neighbors and classmates. A significant 61% of U.S. adults deem close friendships as pivotal to leading a fulfilling life, surpassing the importance of marriage, children, or financial wealth. While a majority (53%) report having between one to four close friends, there's a concerning 8% with no close friendships, highlighting a potential loneliness issue. How many friends do Americans have? A survey crunched the numbers : NPR. (thanks, Dave Pell, NextDraft)

Black Licorice

Happy Halloween! Beware if you plan to raid your family's candy stash, especially if you prefer authentic black licorice. Here are some of the health implications of binging on black licorice (but not red) from the National Center for Complementary and Integrative Medicine. Licorice Root - NCCIH.

064 - AI Lucid Dreams, Long Covid, and Glowing Guts - HealthHippieMD Week In Review

Getting Gold through Crowdfunding

Olympic gymnast Mary Lou Retton joined the ranks of countless Americans, turning to crowdfunding to cover her substantial medical expenses incurred during a battle with rare pneumonia. Her daughter launched a fundraising campaign on Spotfund, and the public rallied, astonishingly raising $350,000 in under two days, surpassing the $50,000 goal. This peculiar juxtaposition highlights the harsh reality of healthcare costs in the U.S., where a quarter million Americans initiate crowdfunding campaigns yearly. Sadly, most don't reach their targets; studies show that 16% receive no donations. This underscores the stark inequalities within the American healthcare system. Mary Lou Retton Crowdfunded Her Medical Debt, Like Many Thousands of Others - The New York Times. (gift article)

Scientists Unearth New Clues to Long Covid

In an unexpected twist in Long Covid, researchers suggest that the villain might be lurking in the gut. In a study published in the journal Cell, scientists from the University of Pennsylvania propose that the remnants of the coronavirus residing in the digestive tract could be suppressing serotonin production, the brain's feel-good neurotransmitter. This serotonin shortage could explain the cognitive and neurological symptoms experienced by many Long Covid sufferers. The research offers a fresh perspective on the condition and potential treatment avenues, proving that sometimes the gut feeling isn't just a metaphor. Scientists Offer a New Explanation for Long Covid - The New York Times. (gift article)

FDA Sounds Alarm on Ketamine Misuse

The FDA is raising eyebrows about the reckless use of ketamine, the anesthetic pharmaceutical (and sometimes party drug) that's been rebranded as a depression and anxiety remedy. They're concerned about the growing trend of online marketers doling out ketamine prescriptions via telemedicine, sidelining the need for medical supervision. While ketamine therapy for mental health shows promise, the regulatory haze around it has spurred abuse. The FDA warns that unsupervised use could lead to serious health problems despite its "off-label" legality. Before you consider a virtual consultation for ketamine, think twice. FDA Issues Warning Over Misuse of Ketamine Therapy - The New York Times. (gift article)

How Not To Age

I'm a big fan of Michael Greger and NutritionFacts. Dr. Gregor's new book, How Not to Age, is coming out this December. He has a few previews of the information here: anti-aging | Health Topics | NutritionFacts.org.

Emotional Costs of Sleepless Nights

A Psychology Today article highlights the emotional toll of sleep deprivation. Beyond the evident fatigue, insufficient sleep can destabilize our delicate equilibrium, leading to intensified negative emotions and unpredictable mood swings. It's a poignant reminder that sleep doesn't merely rejuvenate our bodies but also plays a pivotal role in mental well-being. In essence, to remain emotionally balanced, it's imperative to count the hours and make them count. 4 Ways That Sleep Deprivation Can Harm Your Emotional Health | Psychology Today.

Ear's a Thought: Brainwave Buds

Researchers from the University of California, San Diego, have unveiled innovative earbuds to monitor brainwaves and assess health via ear sweat metabolites. Unlike traditional bulky EEG machines, these compact "neuro-buds" offer a non-invasive peek into cognitive states, potentially aiding early diagnosis of neurodegenerative diseases and even providing neurofeedback. The earbuds, embedded with minute electrodes, detect neural electrical activity during various tasks. Additionally, they can gauge stress levels, predict seizure risks, and measure vital metabolites like glucose. As a bonus, they're designed to play calming sounds based on detected neural patterns, offering users real-time mind management. New Brain-Earbuds Can Listen to Brainwaves, Improve Mood, Decrease Stress, and Possibly Predict Stroke and Neurodegenerative Diseases. ^

NCCIH on Rheumatoid Arthritis

NCCIH has a page on the science behind complementary approaches to Rheumatoid Arthritis: 6 Things To Know About Complementary Health Approaches for Rheumatoid Arthritis | NCCIH.

+And a page on paying for Integrative and Complementary Medicine (including insurance coverage): Paying for Complementary and Integrative Health Approaches | NCCIH.

Mediterranean Diet and Exercise Melt Visceral Fat

A recent study revealed that a combination of a reduced-calorie Mediterranean diet and regular exercise can significantly reduce total fat mass and dangerous visceral belly fat. Older participants following this regime gained muscle and lost considerable body fat within a year, with benefits lasting up to three years. Notably, this wasn't merely about weight loss; the program reshaped body composition from fat to muscle. The study underscores the health risks of visceral fat, linked to diabetes, heart disease, and stroke, and emphasizes the transformative potential of diet and exercise on metabolic health. Mediterranean diet and exercise reduce dangerous belly fat, study says | CNN.

Glowing Guts for IBD

An MIT team designed a pill filled with genetically engineered E. coli bacteria that emit light when detecting gut inflammation. The new device was built to aid in treating Inflammatory Bowel Disease. Photodiodes inside the pill capture this glow, while a radio chip broadcasts it externally. Merging moist microbes with dry electronics was tricky, solved with a clever adhesive barrier. After promising tests in pigs, the next step is human trials. As some pursue a "pill cam" for visual diagnostics, this pill offers a luminescent alternative. This microbe-filled pill could track inflammation in the gut | MIT Technology Review.

Sobering Stories: Physicians and Their Mental Health

The Guardian had an article on the physical and mental toll of medicine and medical training, told through the experience of a Harvard Endocrine Surgeon. U.S. surgeons are killing themselves at an alarming rate. One decided to speak out.

Lucid Dreaming with the Help of AI

Eric Wollberg and Wesley Berry have embarked on a futuristic quest with their startup, Prophetic. Taking inspiration from ancient prophets, their "Halo" device pledges to induce lucid dreams through the wonders of generative A.I. After a whirlwind fundraising season garnering over $1 million and support from tech bigwigs like Apple's neurotech team and Elon Musk's Neuralink, the buzz is palpable. But there's a hiccup: Prophetic hasn't triggered lucid dreams yet. Science suggests that inducing such dreams is feasible, but consistently doing so remains unproven, especially with Prophetic's unique method. Prophetic says its Halo device can cause lucid dreams using generative A.I. Can it?

051 - Solace in Sorrow, Oxygen-Enhanced Learning, and Earworms - HealthHippieMD Week In Review

Finding Solace in Sorrow

The article, Good Grief: How to Make the Best of Painful Loss, delves into the realm of grief and offers strategies for coping with the loss of a loved one. Drawing inspiration from a Japanese "wind phone" that provides solace through one-sided conversations with the departed, the article delves into grief's psychological and physiological impact. Debunking the outdated stages of grief highlights the importance of finding meaning, embracing new identities, adopting rituals, and allowing oneself to experience happiness again. Moreover, it emphasizes the power of listening and being present to support those who are grieving.

A Breath of Fresh Air: Oxygen, Learning, and Stroke Recovery

Boost your brain: a simple 100% normobaric oxygen treatment improves human motor learning processes, published in Frontiers in Neuroscience, revealed that inhaling pure oxygen during motor learning tasks accelerated the learning process and improved performance in healthy individuals. The study indicated that oxygen supplementation could be a low-cost and low-risk approach to expedite stroke recovery. While the precise mechanisms behind the benefits of oxygen remain unclear, several new studies are in the works to learn more about this phenomenon. Pure Oxygen Speeds Up Learning. Can It Help Stroke Survivors Recover?

Britain's National Health Service

Although I believe a single-payer system is the only way out of our current healthcare crisis in the U.S. (exponentially higher costs and mediocre to poorer outcomes than our peers), other healthcare models worldwide suffer their own problems. The NY Times had an interesting article on Britain's National Health Service: A National Treasure, Tarnished: Can Britain Fix Its Health Service? - The New York Times (gift article)

Cancer and Family Dynamics

I Have Cancer. I Can't Put My Kids First Anymore is an interesting piece in the Atlantic on how serious illness affects traditional familial roles and relationships.

Weighing the Risks

Regarding weight loss, injectable medications like Ozempic and Wegovy can pose unique risks for older adults. As muscle loss accelerates aging, frailty and the risk of fractures become more significant concerns for individuals over 65. These drugs, which cause rapid weight loss, often reduce muscle mass, which can negatively impact overall health. Experts emphasize the importance of maintaining muscle mass through strength training exercises and protein consumption to mitigate these risks in older adults. Risks of Ozempic, Wegovy and Other Weight Loss Drugs for People Over 65 - The New York Times (gift article)

Unraveling Earworms

Wired explores the perplexing phenomenon of earworms—those catchy tunes that repeat in our heads. Delving into the science behind these musical intruders, the article examines the triggers of recency, familiarity, and boredom that make songs get stuck in our heads. With insights from experts, it unveils strategies to banish earworms, including completing the song, distracting oneself, diversifying playlists, and even mixing up the lyrics. Why Songs Get Stuck in Your Head—and How to Stop Them.

Privacy and Generative AI

Wired published an informative article on things to consider about privacy while using the new generative AI tools: How to Use Generative AI Tools While Still Protecting Your Privacy | WIRED

Private Equity Firms and Healthcare

Reading this article about equity firms buying physician practices made me feel sick: Who Employs Your Doctor? Increasingly, a Private Equity Firm. (gift article). And we wonder why there's a Moral Crisis of America's Doctors. (gift article).

The Neurophysiology of "I" and Me

Researchers have shed light on how the brain creates our physical sense of self. By stimulating a specific brain region known as the anterior precuneus, scientists caused individuals to experience feelings of floating, dizziness, and detachment from their bodies. This discovery, coupled with understanding the "me" aspect located in the default-mode network, brings us closer to comprehending the complexities of our self-perception. Further investigations may help treat conditions like depression and dissociation while explaining intriguing phenomena like out-of-body experiences. How the Brain Creates Your Physical Sense of Self.

Record-Breaking Temperatures: Climate Change?

The Economist weighs in: Are the current heatwaves evidence that climate change is speeding up?

Your Food and Climate Change

Curious about how the food you eat influences climate change? The NY Times has some answers: Your Questions About Food and Climate Change, Answered

Beyond's Plant-Based Meats and Heart Disease

Michael Gregor discusses plant-based meat and the SWAP Trial: Are Beyond Meat Plant-Based Meat Alternatives Healthy?

042 - Quantum Biology, Wearables, and Birdsong - HealthHippieMD Week In Review

Quantum Biology

This scientist believes nature has harnessed "quantumness" and that our current beliefs about biology are sorely incomplete: Quantum physics proposes a new way to study biology – and the results could revolutionize our understanding of how life works.

Pushing Our Kids to Achieve

Do we do our kids a disservice by pushing them to achieve? This author thinks so: Opinion | What We Lose When We Push Our Kids to 'Achieve' - The New York Times (gift article)

The Newest College Admission Scam: Publish a "Scholarly" Paper

An emerging industry of research services is helping high school students produce and publish research papers to boost their college applications. Online programs, such as Scholar Launch, charge thousands of dollars to connect students with mentors who guide them in writing articles, which are then published in journals of questionable quality. The Newest Way to Buy an Advantage in College Admissions.

Resisting Alzheimer's

Patients whose health doesn't conform to expectations can offer new insight into a possible disease treatment. Such is the case with a man who, based on his D.N.A., "should of" developed Alzheimer's in his 40s but showed resilience to the disease. Mutation Protected Man From Alzheimer's Disease, Hinting at Treatment. (gift article)

WHO Says "No" to Non-Nutritive Sweeteners

The World Health Organization (W.H.O.) has cautioned against using artificial sweeteners for weight control and reducing the risk of noncommunicable diseases. The W.H.O. stated that these alternatives to sugar do not effectively reduce body fat in adults or children and could potentially increase the risk of Type 2 diabetes, cardiovascular diseases, and mortality. This recommendation contradicts previous studies that suggested no harm from sweeteners. Based on a comprehensive review, the W.H.O.'s advice emphasizes the importance of reducing overall sugar intake and relying on naturally occurring sugars found in fruits and unsweetened foods and beverages. World Health Organization Warns Against Using Artificial Sweeteners (gift article)

Therapy Unpacked

Therapy once stigmatized as a luxury for the neurotic, has gained acceptance and popularity over the years. This article explores the effectiveness of talk therapy in improving mental health. While studies suggest that therapy indeed works and yields positive results, there are ongoing debates and challenges in the field. Researchers are trying to determine the best types of therapy for different individuals and understand the impact of the therapist-patient relationship. Some argue for a shift toward more innovative strategies, while others believe therapy's potential hasn't been fully unlocked. Ultimately, the therapist's skills and the bond formed with the patient are crucial to therapy's success. Does Therapy Work? Let’s Unpack That. (gift article)

New Manuscript Defines Frequency of Chronic Pain

"New cases of chronic pain occur more often among U.S. adults than new cases of several other common conditions, including diabetes, depression, and high blood pressure." A new analysis points to the high disease burden of chronic pain in the U.S. U.S. National Survey Data Show High Rates of New Cases and Persistence of Chronic Pain.

The Slumbering Successes of Innovation in Nature and Culture

In his book "Sleeping Beauties: The Mystery of Dormant Innovations in Nature and Culture,", biologist Andreas Wagner discusses how many brilliant ideas and innovations fail immediately but instead emerge and persist in the shadows until the right time arrives for them to step into the limelight. Wagner argues that the success of an innovative product, whether it's a new form of life or a work of art, depends not only on its inner qualities but also on the right environment and timing. He emphasizes the importance of understanding delayed success and empathizing with oneself in the creative process. Why Many Brilliant Ideas Don't Succeed Immediately.

Patients Hack Wearables to Monitor Chronic Illness

"What we have right now is a health and wellness industry that provides data-driven insights and data-driven advice, so long as their physiology is typical." How Chronic Illness Patients Are 'Hacking' Their Wearables describes how patients are using consumer electronics, such as the Oura Ring, Fitbit, and Apple Watch to monitor less common chronic illnesses.

Burned-Out on Burnout

How to address physician burnout. discusses the issue of physician burnout and challenges the prevailing approach to addressing it by embracing the humanities. I think the article misses the point or at least gives only a partial solution. Rather than implying burnout is a personal failing, it should be considered a healthcare system failure. One of my favorite papers on this subject was written by Tait Shanafelt before the pandemic: Executive Leadership and Physician Well-being: Nine Organizational Strategies to Promote Engagement and Reduce Burnout.

Birdsong and Mental Health

Research has consistently demonstrated that more contact and interaction with nature improves physical and mental well-being. Scientists are examining whether birdsong contributes to nature's positive effects: Why birds and their songs are good for our mental health. (gift article)

Banning Food Dyes

"They have no known nutritional benefits and potentially carry several health risks." The Atlantic had a story on efforts around the world to ban artificial food coloring: The True Danger of Food Dye.

040 - Terminal Lucidity, Longevity, and Empathetic ChatBots - HealthHippieMD Week In Review

Terminal Lucidity

"Sometimes, people with dementia who hadn't been coherent for years will suddenly revert to their mentally sharp selves for up to several hours -- and then die shortly after." Scientists are interested in the cause of "paradoxical lucidity" and how it might inform the neuroscience of dementia. Scientists are finally taking a closer look at terminal lucidity.

The Hidden Cost of Amazon Clinic

Amazon's foray into healthcare, Amazon Clinic, (011 - CVS, Amazon, and the Disruption of Primary Care, Anxiety Inoculants, Wabi Sabi, and A.I. - HealthHippieMD Week In Review — HealthHippieMD) keeps the monetary cost of seeing a healthcare professional low but at the cost of your medical privacy. "Signing an authorization isn't a "waiver" of your rights, but you're consenting to your data being disclosed for additional purposes, at which point it leaves the protections of HIPAA." The Washington Post explains: Amazon Clinic patients must sign away some privacy rights under HIPAA. (gift article)

Gut Feelings

"As we wait to establish causal influences through clinical trials, clinicians should advise patients suffering from mood disorders to modify their diet by increasing the intake of fresh fruits, vegetables, and whole grains, as these provide the required fuel/fiber to the gut microbiota for their enrichment, and more short-chain fatty acids are produced for the optimal functioning of the body." More evidence that the microbiome and metabolome drive major depressive episodes. Read the manuscript here: Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs. Control Individuals | Depressive Disorders and synopsis here: Disrupted Gut Microbiome a Key Driver of Major Depression?

+More on the link between ultra-processed foods, mental health, and cognition: How Eating Ultra-processed Foods Can Affect Your Mental Health. (gift article)

Learning Man

You've heard of the music/culture festivals Burning Man and Coachella, but did you know there is a similar gathering focused on immersing attendees in education, play, and creation? Yep, 'Learning Man' is becoming a thing

The Mechanics of Smell

These scientists are striving to understand the mechanism behind human olfaction: How a Human Smell Receptor Works Is Finally Revealed.

Loneliness

Vivek Murthy, America's Surgeon General, is back in the news again, talking about the loneliness epidemic: Loneliness is a Health Crisis, Surgeon General Says. Here's How to Combat It. (gift article) Also see his excellent book on the topic: Together: The Healing Power of Human Connection in a Sometimes Lonely World.

The Modern World is Aging You and Your Brain

An interesting article in Wired about studies examining the brains of non-industrialized societies vs. Western Society: The Modern World Is Aging Your Brain. And the manuscript that inspired the article: Brain volume, energy balance, and cardiovascular health in two nonindustrial South American populations.

Mental Health Chatbots

An article in the N.Y. Times about Pi, an emotional support chatbot: My Weekend With an Emotional Support A.I. Companion. (gift article) These new products remind me of the science fiction movies: Her (film))and Ex Machina (film).) The lines of human characteristics such as empathy and even consciousness are blurring......

"Functional Neurological Disorders"

A long-form read about how Long Covid influences understanding "functional" disorders like ME/CFS (Chronic Fatigue). Contrary to historical thinking, the diseases ARE NOT in the patient's head: We Might Have Long Covid All Wrong

Shady Longevity Research

The quest to conquer aging rages on. Mixed in with traditional scientists are upstarts trying to cash in on a human fountain of youth. Wired had an expose/overview of one of these companies, BioViva, and its founder Liz Parrish: Inside the Secretive Life-Extension Clinic.

Run AwAI

AI has constantly been in the news since last November when OpenAI made its public debut. This week President Biden hosted a meeting at the White House concerning the dangers of A.I. Along those lines, one of the scientists who made significant contributions to the birth of A.I. quit his decade-long stint at Google to talk freely about the risks: Geoffrey Hinton leaves Google, warns about the dangers of AI. (gift article)

+AI is getting better at translating brain activity into words: A.I. Is Getting Better at Mind-Reading

Do Ovaries Hold the Secret of Longevity?

The ovaries age much more quickly than the other tissues of the human body. Scientists think understanding why may hold the key to a longer, healthier life: The Secrets of Aging Are Hidden in Your Ovaries.

Seven Types of People You Need in Your Life

Interesting article in TED about the people you need in your life to counteract stress: The seven types of people you need in your life to be resilient

013 - Horseshoe Crabs, Nightmares, and Dementia - HealthHippieMD Week In Review

Nightmares and Dementia

Are frequent nightmares an early sign of impending dementia? This researcher thinks so. Having this many nightmares a week may be tied to extreme brain aging.

Horseshoe Crabs and the Pharmaceutical Industry

Most people don't realize that crab blood is critical to the modern pharmaceutical industry. Horseshoe crab's blue blood contains a compound that protects humans from infected medical supplies. How horseshoe crab blood became one of the most valuable liquids in medicine. Radiolab also has a great episode on this topic: Baby Blue Blood Drive.

Understanding the High Cost of Living Life Online

Studies have found that frequent social media use is connected with increased symptoms of anxiety and depression. The article, The High Cost of Living Your Life Online, discusses some reasons and how to combat those negative feelings.

The Healthiest Bedtime for Metabolic Health

A recent study, Early chronotype with metabolic syndrome favors resting and exercise fat oxidation in relation to insulin‐stimulated non‐oxidative glucose disposal, found that being a night owl negatively affects metabolic health. Early risers burn more fat when fasting or exercising: Going to bed before this time could boost your metabolic health.

Paul McCartney's Freakish Memory

This article is a stretch from medicine and wellness, but being a music and Beatles lover, I had to include it. Paul McCartney's freakish memory, delighted me, offering insight into the unconscious mind and a glimpse into McCartney's songwriting process. And now I love Paul McCartney even more.....

Ten Modern Paradoxes

I include this thought-provoking article because of the first paradox mentioned, hedonism. _"...psychologist Viktor Frankl wrote, "Happiness cannot be pursued; it must ensue, and it only does so as the unintended side effect of one's personal dedication to a cause greater than oneself or as the by-product of one's surrender to a person other than oneself." 10 paradoxes that will stretch your mind.

The Gut-Brain Axis in Mental Health

Thought to be fringe science only a few years ago, hundreds of scientists are now racing to unravel the microbiome's role in mental health. The article, What does the latest science tell us about our brain, gut, and mental health, gives a whirlwind tour. Also, see my lecture on the gut-brain axis: Gut Feelings: the role of the microbiome in behavioral health.

The Physiology and Neuroscience of Tickling

I approached the article, Why Can't You Tickle Yourself, with skepticism, but ended up learning quite a bit. I'm going to look more into the science of playfulness.

Why We Do Things We Know We'll Regret

" Use your resources joyfully, without guilt or shame for your abundance. But use your bounty in service of the love you have for others. Beyond your everyday needs, buy time and experiences with your loved ones. Support the people and causes you care about. Invest in getting to know others deeply. While you're at it, beyond your generosity with your money, give more of yourself by sharing your heart with honesty and defenselessness. Tell more people you love them, even when it is a little awkward or scary." I enjoyed this article by Arthur Brooks: Why We Do Things We Know We'll Regret.

The Pandemic Changed our Personalities, and not for the Better

Social scientists think of personality as being relatively stable throughout one's life. But, there is increasing evidence that the pandemic altered many of our personalities, and not for the better: The COVID pandemic may have had a lasting impact on personality traits

Fungi and Cancer

Two interesting articles were published in this week's Cell demonstrating an association between intracellular fungal DNA and cancer lethality in multiple cancer types. Despite the finding, neither study can definitively say if fungi drive these poor outcomes or if aggressive cancers create an environment where these fungi can quickly grow. The studies also don't address if fungi can contribute to cancer development, pushing healthy cells to turn cancerous. The finding opens the door to a new research domain: Fungi grow inside cancerous tumors, scientists discover.

Facing Down Loneliness and Heartbreak

Emerging scientific data suggests that social rejection — often in the form of heartbreak — can spark a similar firestorm of brain activity as physical pain. Vivek Murthy, United States Surgeon General, classifies loneliness as a public health crisis. But loneliness can be hacked: An antidote to heartbreak? Science reveals how to hack loneliness. See also the book, Heartbreak: A Personal and Scientific Journey, mentioned in the article and Vivek Murthy's book Together.

Physician Burnout

Physician burnout was a problem before the pandemic and has only accelerated during Covid times. I was well aware of the phenomenon, but what I was not aware of was that burnout is contagious: Physician Burnout Has Reached Distressing Levels, New Research Finds.

Can Technology Prevent Suicide?

Finally, I read an article on attempts to use technology to predict and contribute to suicide prevention: Can Smartphones Help Predict Suicide

Quote of the Week

"The saddest aspect of life right now is that science gathers knowledge faster than society gathers wisdom." ―Isaac Asimov

002 - Hangover Pills, Animal Dreams, and Sound - HealthHippie Week In Review - July 24, 2022

Here are a few of the interesting stories I read this week...

Chronic Fatigue and Covid

Freakonomics, M.D.: 46. Could Long Covid Help Treat Other Chronic Illnesses? on Apple Podcasts This was an interesting discussion about the similarities between Long Covid and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome(ME/CFS). I learned that ME/CFS is the most underfunded disease in the NIH portfolio relative to disease burden. Interestingly, there was no mention of the influence of the microbiome. I will be astounded if changes in the microbiome aren't involved with (or even responsible for) both diseases.

How to Hack Intrusive Thoughts

"It's not about controlling your thoughts; it's about not letting the thoughts control you..." This was the opening statement in the article A psychiatrist's guide to coexisting with intrusive thoughts. The report is a summary of If you don't let it in, you don't have to get it out: Thought preemption as a method to control unwanted thoughts.A 2020 NIH survey reported more than 1 in 5 Americans have a mental illness, but even a higher percentage have unwanted or obsessive thoughts. Rumination can adversely affect longevity as well as physical and mental well-being. The best take-home advice from the article was "We encourage people to think of intrusive thoughts as strangers at a party who drift into a room that you might happen to be in, you might engage with them for a little bit, but then eventually, they wander out the other door, and you may not spend too much time engaging with them.".

Inflammatory Bowel Disease and Depression

More interesting news on the gut-brain axis. A new study, Bidirectional association between inflammatory bowel disease and depression among patients and their unaffected siblings demonstrated a bidirectional link between Inflammatory Bowel Disease and Depression. The findings were summarized in New study shows a bidirectional link between inflammatory bowel disease and depression

Anthropause

The article Did Nature Heal During the Pandemic' Anthropause' is fascinating. "Anthropause" is what scientists named the slowdown of human activity during the Covid-19 Pandemic. Interestingly, according to the authors, the impact of diminished human activity is both positive AND negative.

Superbugs

The pandemic has impacted healthcare well beyond patients that contract Covid. I read a depressing article, The Pandemic Fueled a Superbug Surge. Can Medicine Recover?, about how the pandemic influenced a rapid rise in deadly resistant superbugs that will impact us all. The article was written in response to a recent CDC report, COVID-19, U.S. Impact on Antimicrobial Resistance. Unfortunately, not much good news there that brings greater urgency to out-of-the-box thinking to treat infections such as last week's story on Maggot Therapy.

Combatting Burnout

Burnout: How to recover and enjoy your free time is an interesting article on how burnout has reached epic proportions during the pandemic, and how to cope. The main points I took from the article:

  1. The more stressful the job, the more difficult it is to recover and the more significant the impact on self-care behaviors.
  2. Scientists group downtime into two categories: relaxation and mastery (and the importance of mastery in recovery).
  3. The importance of self-directed downtime activities.
  4. The importance of regularly separating oneself from work.

Sabine Sonnentag wrote an excellent review on the topic: Recovery from Work: Advancing the Field Toward the Future | Annual Review of Organizational Psychology and Organizational Behavior Also see my article on Time Poverty.

A Probiotic Pill for Hangovers? Not So Fast!

In my blog entry, Are Probiotics Making You Fat? probiotics, prebiotics, and fermented food,, I warned about the over-zealous promotion of probiotics as a miracle cure-all. Myrkl: new anti-hangover pill said to break down 70% of alcohol in an hour, is a perfect example of the need for caution. This is the latest instance I've read about of a companies trying to cash in on the probiotic gold rush. Myrkl, recently released in the U.K., is an enteric coated pill (resistant to stomach acid) that delivers a load of Bacillus subtilis and Bacillus coagulans to the small intestine. The company claims the two bacteria break down alcohol, thereby preventing a hangover. Putting aside the fact that a hangover is caused only indirectly by alcohol, the claim Myrkl can "cure" hangovers is based on a single, weak, poorly designed, non-generalizable investigation. I also disagree with the author of the article that probiotics are entirely safe--we don't know enough about them to make that claim. Buyer beware!

Do Animals Dream?

The article, Do Animals Dream, is a review of the book When Animals Dream: The Hidden World of Animal Consciousness. I'm adding this to my queue.

Turtle Time

There are three ways to die: injury, disease, or old age. The aging process is called senescence, the gradual breakdown of bodily functions. The article, What Turtles Can Teach Humans About the Science of Slow Aging, discusses recent studies that examine the factors contributing to the prolonged aging process of turtles. By studying slow-aging species, scientists hope to gain insight into human healthspanmight be improved.

An Apple A Day

Apple released a 65-page reporton their activities in the healthcare and wellness space. I'm working my way through the report now. Big tech is finally deeply embracing healthcare: see this article in the Economist about Alphabet/Google (Alphabet is spending billions to become a force in health care) and Amazon (Amazon to Acquire One Medical Clinics in Latest Push Into Health Care.) Amazon and other large corporations aim to control a portion of their healthcare expenditures by bringing primary care in-house rather than paying incumbent health systems and insurers. The tech giants and other prominent players (e.g., national pharmacy chains like CVS and Walgreens and retailers like Walmart) will ultimately attempt to keep their company workforce healthy (through wellness and preventative care) and OUT of incumbent health systems. Healthcare tech development is the first phase of what promises to be a massive shift in healthcare: Deloitte Estimates Wellness will Play a $3.8 Trillion Role in the Future of Medicine.

Weekend Warriors

A study published in JAMA Internal Medicine, Association of the "Weekend Warrior" and Other Leisure-time Physical Activity Patterns With All-Cause and Cause-Specific Mortality, showed that Weekend Warriors, those who only engage in exercise on the weekends, had many of the same reduction in the risk of dying as those that exercised more frequently.

Arthur Brook's Three Biggest Happiness Rules

I'm a big fan of Arthur Brook's How to Build a Life Series in The Atlantic. The article, A Happiness Columnist's Three Biggest Happiness Rules, is worth a read. The best quote: " Happy people love people and use things; unhappy people use people and love things."

Sleep and Sound

I read an interesting article on how your brain is still responsive to sound during sleep, The missing conductor: Your brain still hears sound as it sleeps. It made me think of the work at MIT looking at specific frequencies of sound and light and their effect on immune function Alzheimer's Disease and Gamma Waves. The article made me wonder if I should play particular frequency sounds while sleeping.