120 - Mirror Cells, Fighting Inflammation with Food, and Artful Healing - HealthHippieMD Week In Review

120 -- HealthHippieMD Week In Review Audio Overview

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Curiosity Killed the Bias

How to see the humanity in anyone | Psyche Guides explores the transformative practice of "deep curiosity," a tool for fostering empathy, connection, and understanding across divides. The author recounts a yearlong journey meeting individuals with opposing beliefs and challenging stereotypes fueled by assumptions and social media. Through the DIVE model—Detach, Intend, Value, Embrace—he teaches how to unlearn biases, prepare for meaningful dialogue, and honor others' dignity. By viewing challenges as opportunities for growth, deep curiosity strengthens relationships and enriches self-awareness. This guide empowers readers to break barriers and connect authentically in an increasingly polarized world. (Thanks, Laura!).

+see also: The War For Kindness - The Happiness Lab with Dr. Laurie Santos - Apple Podcasts.

Food Fights Inflammation

An anti-inflammatory diet swaps processed foods for whole, nutrient-dense options to combat chronic inflammation. Foods rich in antioxidants, polyphenols, and essential nutrients help reduce oxidative stress and regulate hormones. A Mediterranean-inspired diet—packed with fruits, vegetables, fish, nuts, and olive oil—nurtures a healthy gut biome, while magnesium-rich and brightly colored foods fight stress and free radicals. Spices like turmeric and garlic add flavor and anti-inflammatory benefits. While diet is just one piece of the wellness puzzle, adopting these habits offers long-term physical and mental health benefits—making it a marathon worth running. An anti-inflammatory diet can boost your health. What to eat and what to avoid | Fortune Well.

How Seed Oils May Ignite Cancer Risks

A new study highlights the potential role of omega-6 fatty acids—abundant in seed oils used in ultra-processed foods—in promoting inflammation that fuels colon cancer. Researchers found high levels of these proinflammatory lipids in tumor samples, alongside a deficiency in inflammation-resolving omega-3s. Experts point to dietary shifts since the 1950s, with ultra-processed foods and seed oils dominating modern diets, as a likely factor. While diet isn't the sole contributor, the findings emphasize the complex interplay of food, lifestyle, and genetics in cancer risk, advocating for moderation in omega-6 consumption pending further research. Ultraprocessed Foods High in Seed Oils Could Be Fueling Colon Cancer Risk | Scientific American.

Chasing Happiness

What can ancient philosophy teach us about a well lived life? Examining different schools of philosophical thought can teach us a lot about different ways to create happiness. The philosophy of happiness, explained in 10 minutes - Big Think.

Love Is a Marathon, Not a Sprint

Arthur C. Brooks explores the paradox of love and happiness, arguing that the exhilarating, passionate phase of romance—while thrilling—isn't what brings enduring joy. Instead, he highlights "companionate love," rooted in friendship, mutual understanding, and commitment, as the foundation of lasting happiness. Backed by research like the Harvard Study of Adult Development, Brooks demonstrates that stable relationships, especially those built on deep friendship, are the strongest predictors of lifelong contentment. With humor and personal anecdotes, he underscores that the secret to staying in love lies in simply liking your partner—your best friend. The Kind of Love That Makes People Happiest - The Atlantic.

+see also: This heartwarming video from Coldplay featuring Dick Van Dyke. All My Love Official Version, Director's Cut.

Press Paws

A recent study suggests that dogs may communicate intentionally by pressing buttons linked to words. Researchers found that some dogs form two- or three-word combinations, such as "want food," which appear deliberate rather than random. The study monitored button-pressing behaviors in over 150 dogs using soundboards, finding that dogs can express needs akin to a young child. However, skeptics argue the behavior could stem from training or reinforcement rather than true language understanding. While questions remain, the research highlights dogs' intelligence and their potential for deeper interaction with humans. Dogs may be able to communicate by pressing buttons, research suggests - The Washington Post (gift article).

Snooze You Can Use

Science-Backed Sleep Tips from 2024 to Help You Snooze Better | Scientific American explores 2024's popular sleep trends and their scientific validity. Highlights include the benefits of short naps for memory and mood and caution against "bed rotting," which disrupts circadian rhythms. TikTok's "sleepy girl mocktail" sheds light on magnesium's role in relaxation, while sleeping on the floor offers mixed results for back health. Sleep divorces—partners sleeping separately—can improve rest for mismatched sleepers. To combat election-induced insomnia, experts recommend unplugging, meditating, and reframing anxious thoughts with gratitude. These evidence-backed strategies aim to optimize sleep quality for a more restful 2025.

Artful Healing

Susan Magsamen's exploration of neuroaesthetics reveals the profound effects of art on mental health, trauma recovery, and cognitive disorders. This emerging field connects art, science, and well-being, showing how aesthetic experiences—from painting and dance to music—positively reshape our brains. Programs like Creative Forces empower trauma survivors, while dance improves cognition and mobility in Parkinson's patients. The arts, accessible to all, offer transformative benefits, reducing stress and fostering resilience. By embracing creativity, we can enhance our mental and physical health, proving that the arts are as essential as exercise or nutrition. 'Neuroaesthetics' Reveals How the Arts Help with Dementia and Trauma | Scientific American.

Neuroinflammation and Muscle Fatigue

Neuroinflammation, sparked by the brain's immune response to infections or chronic diseases like Long COVID and Alzheimer's, disrupts the brain-muscle connection, leading to muscle fatigue. This research uncovers how brain-released cytokines alter muscle energy production without damaging muscle structure. Studying fruit flies and mice, scientists identify a universal brain-to-muscle communication pathway that reallocates energy to combat infection. Potential treatments, such as neutralizing antibodies, aim to block this signaling. With further exploration, targeting this axis could alleviate fatigue in long COVID and other neuroinflammatory conditions, improving life for millions worldwide. Brain inflammation may be the reason behind muscle fatigue after infection and injury.

Mirror Cells: The Dark Reflection of Life

Scientists warn of the existential risks posed by "mirror cells," organisms built with reverse-handed DNA and proteins, defying the fundamental biology of Earth's life forms. These synthetic microbes, immune to natural defenses and capable of ecological devastation, could trigger pandemics or disrupt ecosystems if released. While promising medical advancements like long-acting drugs, their potential to bypass immune systems and evolve uncontrollably outweighs the benefits. Leading researchers advocate banning this technology, urging global dialogue to prevent catastrophic consequences before these innovations take root. A 'Second Tree of Life' Could Wreak Havoc, Scientists Warn - The New York Times (gift article).

+see also: one of the most memorable articles from Wired (from 25 years ago!)-Why the Future Doesn't Need Us | WIRED.

The Gut: The New Frontier of Mental Health Treatment

Emerging research highlights the potential of targeting gut cells, rather than brain cells, to treat depression and anxiety. Traditional SSRIs, while effective, often cause systemic side effects. Scientists have observed mood improvements in mice without the usual drawbacks by focusing on serotonin production in the intestines, unveiling the gut-brain connection's crucial role in emotional regulation. This novel approach may also address concerns about SSRI safety during pregnancy, offering a safer alternative for both mothers and babies. These findings could revolutionize mental health care by delivering effective relief without compromising physical well-being. Drugs targeting gut cells, not brain cells, fight depression better - Earth.com. (thanks, Amy!).

+see also: Gut Feelings: The Role of the Microbiome in Behavioral Health — HealthHippieMD.

097 - The Write Stuff, Fish Oil Debate, and Awe - HealthHippieMD Week In Review

Mind-Expanding Reads for Daily Life

This article reviews five essential psychology books that simplify complex theories into practical advice for daily life. Thinking Fast and Slow by Daniel Kahneman explores cognitive biases and decision-making processes. Carol Dweck’s “Growth Mindset” emphasizes the power of effort over innate ability. “Emotional Intelligence” by Daniel Goleman highlights the importance of understanding and managing emotions. Angela Duckworth’s “Grit” focuses on resilience and perseverance. Finally, “Flow” by Mihaly Csikszentmihalyi delves into achieving optimal experiences. Each book, authored by experts, offers actionable insights to enhance personal and professional life. 5 applied psychology books for everyday life - Big Think.

Awe

Lori Santos covered the eight types of awe in her podcast The Happiness Lab with Dr. Laurie Santos: The Power of Awe. Well worth a listen whether you are religious or not.

Gaslight, Camera, Action

Gaslighting, a manipulative tactic that makes victims question their reality, can profoundly affect mental health, leading to anxiety and depression. When confronted with gaslighting, experts recommend seven strategies to regain control and assert your truth. These include calmly stating your perspective, setting boundaries, validating your feelings, documenting events, suggesting neutral third-party mediation, using humor to defuse tension, and focusing on solutions rather than memory debates. These techniques aim to disrupt the manipulator’s control and provide clarity, helping you maintain your sense of reality and well-being. 7 Things to Say When Someone Gaslights You.

Unraveling Chronic Illness Misdiagnoses

Chronic illness symptoms are frequently dismissed as mere stress, complicating diagnosis and treatment. Amina AlTai, initially attributing her fatigue and brain fog to work-related stress, faced repeated dismissal from doctors despite worsening symptoms like hair loss and gastrointestinal issues. It wasn’t until thorough blood tests that she was diagnosed with Hashimoto’s disease and celiac disease, severe autoimmune conditions. This case underscores the complex interplay between stress and chronic illness, highlighting the need for careful evaluation to distinguish between stress-related symptoms and underlying medical conditions. Why Chronic Illness Symptoms are Commonly Dismissed as Just Stress - The New York Times (gift article).

Weight Loss Woes

States like West Virginia are grappling with the high costs of weight-loss drugs like Ozempic and Wegovy. Despite their effectiveness, with some patients losing 15-20% of their weight, the prohibitive costs, reaching up to $1,400 a month, make them inaccessible for many. Canceling public funding programs exacerbates the disparity between those who can afford these medications and those who cannot. Critics argue that the situation mirrors past pharmaceutical crises, underscoring a broader issue of healthcare inequality in treating obesity, a condition classified as a complex disease. Some States Say They Can’t Afford Ozempic and Other Weight Loss Drugs - The New York Times (gift article).

Time for a Pill

MIT researchers have discovered that the effectiveness of medications depends significantly on the time of day they are taken due to circadian variations in liver function. Using engineered mini-livers, the study identified over 300 liver genes with circadian patterns, affecting drug metabolism and inflammation. These findings suggest that drug regimens could be optimized to enhance efficacy and reduce toxicity. For instance, Tylenol’s breakdown is more efficient at specific times, and the liver’s susceptibility to infections like malaria varies with the circadian cycle. This research opens new avenues for tailoring drug administration schedules. Drugs are more effective at certain times of day | MIT Technology Review.

The Fish Oil Debate

The article explores the ongoing debate about the efficacy of fish oil supplements for heart health. Despite early enthusiasm sparked by Inuit dietary studies, recent research reveals mixed results. Some studies suggest omega-3s reduce coronary events, but many trials show no significant cardiovascular benefits. Additionally, fish oil supplements may increase the risk of atrial fibrillation. Experts recommend obtaining omega-3s from dietary fish rather than supplements, emphasizing a balanced diet and healthy lifestyle for heart health. The article underscores the importance of relying on well-rounded dietary practices rather than supplements for optimal cardiovascular well-being. Is Fish Oil Helpful or Harmful for the Heart? - The New York Times (gift article).

Reclaim Your Work-Life Balance

In an era of remote work and constant connectivity, achieving work-life balance has become increasingly challenging. The article outlines five tech-based strategies to prevent work from encroaching on personal time. These include setting and communicating boundaries, scheduling messages during work hours, minimizing notifications, filling calendars with buffer times, and establishing emergency contact plans. By leveraging the same technology that blurs the line between work and personal life, individuals can regain control and ensure their jobs stay within the confines of a typical workday. How to get back your work-life balance with tech - The Washington Post (gift article).

AI: The Write Stuff

A recent study reveals that over 10% of scientific papers are co-authored by large language models (LLMs) like ChatGPT, with fields like computer science showing even higher usage. Researchers from the University of Tübingen and Northwestern University utilized an excess-vocabulary method to identify unusual word frequencies in scientific abstracts. This method bypasses traditional detection algorithms, revealing the widespread integration of AI in academic writing. While LLMs enhance drafting efficiency, especially for non-native English speakers, their use raises concerns about biases, hallucinations, and the potential flood of low-quality publications. Academic policies on LLM usage remain inconsistent and evolving. At least 10% of research may already be co-authored by AI.

085 - Healthcare AI, Love's Faces, and Crafting a Sharper Mind - HealthHippieMD Week In Review

Timing is Everything

The optimal time for exercise is influenced by circadian rhythms, which govern physiological and behavioral patterns over a 24-hour cycle. Research shows that exercise timing can impact health and athletic performance. Morning exercise may help align the body's circadian rhythms, while afternoon exercise is often associated with peak physical performance. Muscle cells have their clocks, which can be trained to optimize performance at specific times of day. Consistency in exercise timing may also be beneficial for long-term health. Studies are exploring how exercise timing can be used to manage conditions like metabolic syndrome and diabetes, with some evidence suggesting that afternoon exercise may be more beneficial for those with Type 2 diabetes. However, the science is not yet settled, and individual preferences and schedules should be considered when determining the best time to exercise. Best time to exercise? How circadian rhythms affect your workout and your health: Shots - Health News : NPR (thanks, Wendy!).

Love's Familiar Faces

The concept of a romantic "type" may stem from psychological comfort rather than random attraction. Studies suggest we're drawn to partners with similarities in physical, psychological, and educational traits, often due to demographic factors and "assortative mating." Familiarity also plays a role, as we may seek partners who remind us of past relationships, reinforcing our perceptions of love. Understanding these patterns can help us consciously navigate our romantic choices, recognizing the importance of openness and self-awareness in our relationships. Where Your Romantic 'Type' Comes From - The Atlantic.

Allergy Apocalypse

In a conversation with Yasmin Tayag from The Atlantic, the "allergy apocalypse" is discussed as rising temperatures contribute to longer and more intense pollen seasons. Traditionally marked by tree pollen in early spring, followed by grasses and ragweed, allergy seasons are now starting earlier and lasting longer due to warming temperatures and increased carbon dioxide levels. This change has led to more people experiencing allergy symptoms, even those who previously had a higher tolerance for pollen exposure. The article also explores the impact of allergies on daily life and the limited options for managing symptoms, emphasizing the need for precautions like checking pollen counts and reducing exposure. The increasing pollen levels are causing individuals to spend less time outdoors, impacting their relationship with nature and the enjoyment of warmer seasons. The allergy apocalypse is here - The Atlantic.

Weighing the Odds

Altimmune's experimental weight loss drug, Pemvidutide, has shown promising results in a phase-2 trial, successfully minimizing muscle mass loss. In contrast to other weight loss drugs, which often lead to a higher rate of lean muscle loss, Pemvidutide's clinical study of 391 subjects revealed an average weight loss of 16% over 48 weeks, with 75% of this loss attributed to fat and only 25% to lean mass. This ratio closely mirrors that achieved through diet and exercise. The preservation of lean mass is crucial, especially for women and older people, as excessive loss can result in conditions like sarcopenia and bone fractures. Amidst the booming demand for weight loss drugs, several pharmaceutical companies are racing to introduce new and improved options, with Novo Nordisk even developing a more potent drug following the success of Wegovy and Ozempic.

Daniel Kahneman's Legacy of Learning from Errors

The world lost a titan this week. Daniel Kahneman, the renowned psychologist and Nobel laureate, passed away at 90, leaving a legacy of intellectual humility. Known for his groundbreaking work in behavioral economics and cognitive biases, Kahneman was unique in his persistent admission of his own mistakes, both in public and private. His book, Thinking, Fast and Slow reflects his lifelong journey of self-correction, highlighting the human propensity for errors and the importance of acknowledging them. Kahneman's approach to science was marked by constantly reevaluating his beliefs and an openness to learning from mistakes, a rare quality that made his contributions to psychology and economics invaluable. Even in the face of controversies, such as the reproducibility crisis in psychology, he remained a proponent of rigorous scrutiny and honesty in scientific research. Kahneman's work and willingness to admit faults have left an indelible mark on the field, emphasizing the importance of embracing our fallibility and striving for greater understanding. Daniel Kahneman Was Sometimes Wrong, and Always Right - The Atlantic.

Crafting a Sharper Mind

The New York Times article explores the cognitive and emotional advantages of engaging in hands-on activities like writing, gardening, and knitting. Neuroscience Professor Kelly Lambert highlights the brain's significant investment in hand movement and suggests that working with our hands may offer unique rewards, such as improved problem-solving skills and stress management. Studies indicate these activities can enhance memory, attention, and mental health. Moreover, handwriting, in particular, has been shown to stimulate more elaborate brain activity compared to typing. While the exact mechanisms remain under investigation, the consensus is that hands-on tasks, which require fine motor control and mental engagement, can benefit brain health and well-being. Working With Your Hands Is Good for Your Brain - The New York Times. (gift article).

Healthcare AI in the Economist

The latest Technology Quarterly features AI in healthcare:

• AIs will make health care safer and better
• Artificial intelligence has long been improving diagnoses
• Medical AIs with human faces are their way
• Artificial intelligence is taking over drug development
• Can artificial intelligence make health care more efficient?

Nerve-aid

Neurona Therapeutics' experimental epilepsy treatment, involving brain-cell transplants, shows promising early results. Justin Graves, a volunteer in the trial, experienced a significant reduction in seizures after receiving lab-made neurons injected into his brain. Developed as a breakthrough for stem-cell technology, this treatment uses cells converted to an embryonic-like state to manufacture young, healthy tissue. The therapy aims to restore balance in brain activity by growing inhibitory interneurons that quell electrical misfires causing seizures. While the treatment's long-term efficacy and consistency are yet to be confirmed, the initial success stories offer hope for a new, non-destructive approach to treating epilepsy, potentially shifting the current surgical paradigm. Brain-cell transplants are the newest experimental epilepsy treatment | MIT Technology Review.

038 - Ice Cream, Understanding Animal Communication, and Circadian Immunity - HealthHippieMD Week In Review

Wait, Ice Cream Might be Healthy?

I enjoyed the article, Could Ice Cream Possibly Be Good for You?. The report not only discusses the controversial, non-spurious outcome that won't go away but also demonstrates what happens in the scientific world when a new finding bucks traditional thinking. And the article contains puns.....

How Generative AI Will Change the Music Industry

Generative AI is not just for text and image creation. AI-Generated Music Is About to Flood Streaming Platforms discusses how AI is changing the music industry and music itself.....

Amyloidosis

The same misfolded proteins found in Alzheimer's Disease can also be found in other organs. Alzheimer's-Like Diseases Can Affect the Body — Scientists Are Working to Find Out Why is an overview of Amyloidosis and its treatment.

Chartreuse Shortage

For my 21st birthday, some friends bought me Chartreuse, a bright green herbal liqueur. That was the only time I tasted it. But now, even if I wanted more, it might not be possible. Chartreuse is getting more difficult to find. Why Is There a Chartreuse Shortage? Ask the Monks Who Make It.

Altered States of Memory

"Memory is "reconstructive." People actively alter the information they remember according to their biases and expectations." Short-term memories were thought to be less subject to alteration, but a recent study demonstrates otherwise: Our expectations can create fake short-term memories. If you'd like to learn more about the fragility/malleability of memory, take a listen to one of my favorite Revisionist History episodes: Free Brian Williams.

How Ultra-processed Food Starves the Microbiome

Another article on how processing alters food--and not in healthy ways: You Could Be Unknowingly Starving Your Gut Bacteria — But The Fix Is Surprisingly Simple. I feel like a broken record....

Is "Non-Communicable Disease" a Misnomer?

Human ailments such as heart disease were thought to be non-communicable. But findings from microbiome research call that belief into question: The Biggest Microbiome Study Sheds New Light on Shared Health Risks.

Covid, Population Risk, and Personal Risk

There is a 1% mortality rate from COVID. If 1% of COVID-19 cases result in death, does that mean you have a 1% chance of dying if you catch it?

FDA Approves Second Bivalent COVID Booster

"Federal health officials will not formally urge that people get a second booster. Instead, the "permissive" policy says they may get a second dose if they want." FDA okays second omicron booster for people at high risk from covid

Why Does Hair Turn Grey?

"A new study suggests stem cells may get stuck as hair ages and lose their ability to mature and maintain hair color." Scientists may have discovered why hair turns grey._

Belated Happy Waldo Day!

This week marked 4/20. In honor of the day, Longreads compiled a list of cannabis-related stories: Weed Between the Lines: A Longreads Cannabis Collection.

Talking to the Animals

I've often joked that I wish Theodore, a six-year-old Labradoodle, could talk. Now, thanks to AI and bioacoustics, my wish may become a reality: How Scientists Are Using AI to Talk to Animals.

Food and Hot Flashes

We don't understand the physiology of hot flashes, but it appears food can influence the severity of this common occurrence: Could Certain Foods Help With Hot Flashes? (gift article)

Us versus Them

"It's been said, "There are two kinds of people in the world: those who divide the world into two kinds of people and those who don't." In reality, there are lots more of the former. And it can be vastly consequential when people are divided into Us and Them, ingroup and outgroup, "the people" (i.e., our kind) and the Others." An stimulating article in Nautilus about us/them dichotomies: Why Your Brain Hates Other People.

Reinvent Yourself According to Experts

Giving credence to your "possible selves" is an evidence-based way to reinvent yourself. How to Reinvent Yourself, According to the Experts tells you how. See also the fantastic podcast: zigzag project.

A Key Character Trait for Happiness

Enthusiasm Is Key to Happiness is an interesting article that touches on psychology and finishes with ways of improving your happiness, regardless of personality type.

Huge Umbrella Analysis of Dietary Sugar

The British Medical Journal published an article that aggregated a huge (8600+) studies on the effects of sugar on health outcomes: Dietary sugar consumption and health: an umbrella review. Read the synopsis here: Study Offers Dozens of Reasons to Cut Sugar

Circadian Rhythms and Immunity

How Circadian Rhythms and Time of Day Control the Immune System describes recent breakthroughs into how our body's internal clock seems to regulate immunity and susceptibility to disease.

034 - Social Anxiety, Beethoven's DNA, and Tattoos - HealthHippieMD Week In Review

New Year's Anti-Resolutions and To-Don't Lists

"when you don't know the right way forward, you might succeed by focusing on what you know to be wrong instead." I learned quite a bit from Your bad attitude can make you happier.

Galentine's Day-Dinner with Strangers

The Radical Act of Eating With Strangers was an interesting article about friendship and social connection. I wonder how it might work here in North Carolina. (I ran out of gift articles)

How to Combat Loneliness

An article from Harvard Health with suggestions to combat loneliness: 3 ways to create community and counter loneliness

Social Anxiety - Fear of Failing

What is the neuroscience behind social anxiety, an affliction that affects 40 million people in the U.S.? Fear of Failing: The Secrets Behind Social Anxiety

Steven Pinker Interview

Steven Pinker is an influential cognitive psychologist and author. In the interview, The ultimate guide to rationality, , he touches on "topics such as human progress, the tragedy of the commons, Bayesian reasoning, and strategies to curb our most destructive instincts, with the ultimate goal of improving the world for everyone."

Tattoos and Immunity

The skin is the body's first line of defense. For thousands of years, humans have been decorating their bodies with tattoos. Scientists still aren't sure what happens to our immune system when we receive one.Tattoos do odd things to the immune system

Foods that Fight Inflammation

Here is a brief but informative article from Harvard on anti-inflammatory foods: Foods that fight inflammation

GPT-4 AI Scores 85% on USMLE

Microsoft released a paper this week that showed that the latest GPT model could pass the USMLE: GPT-4 on Medical Challenge Problems - Microsoft Research. +Eric Topal breaks down the implications of AI for medicine: Multimodal AI for medicine, simplified - by Eric Topol

Intelligence and (un)Happiness

"Your intelligence is more likely to bring you happiness if you put it to use by chasing better ways to love and serve others rather than elbowing others aside and hoarding worldly rewards." Another interesting article in the Atlantic's How to Build a Life: Intelligence Is More Than a Tool to Get Ahead

Defining "Life" and "Death."

Technology forces us to reexamine what we consider alive and dead. The ideas are far-reaching, including law, medicine, ethics, and morality. Another thought-provoking article in Wired: The End of 'Life' As You Know It

Applying Scarcity to Gym Membership

Years ago, Robert Cialdini wrote a classic book on sales techniques: Influence, New and Expanded: The Psychology of Persuasion. The rise of pricey, application-only gyms is an exemplar of Cialdini's principles: The Rise of Exclusive, Application-Only Gym Memberships (gift article)

Animal Personality and Scientific Results

Here is an interesting article questioning whether animal personality might alter scientific results. Animal Personalities Can Trip Up Science, But There's a Solution

Cancer and Circadian Rhythm

A study published in Trends in Cell Biology reviewed the influence of circadian rhythms on cancer biology. "The circadian rhythm governs most of the cellular functions implicated in cancer progression, and its exploitation, therefore, opens new promising directions in the fight against metastasis. In this review, we summarize the role of the circadian rhythm in tumor development and progression, with emphasis on the circadian rhythm-regulated elements that control the generation of circulating tumor cells (CTCs) and metastasis. We then present data on chronotherapy and discuss how circadian rhythm investigations may open new paths to more effective anticancer treatments." A new time dimension in the fight against metastasis

Beethoven's DNA

An article on how sleuths tracked down and analyzed strands of Beethoven's hair. The findings are fascinating: DNA From Beethoven's Hair Unlocks Medical and Family Secrets (gift article) and Beethoven's Genome Has Been Sequenced for the First Time, Revealing Clues About the Great Composer's Health & Family History

Meat Lobbies

Here is an article on how the meat industry changed the proposed recommendations of the Intergovernmental Panel on Climate Change report. I learned quite a bit from the article, including that the global beef industry is estimated at around $400 billion and that meat and dairy produce about 14.5% of global greenhouse emissions. The meat industry got the IPCC to edit a climate change report

Using Google Maps to Plan your Vacation

I'm going to try this: How To Use Google Maps Immersive View To Vacation Plan Like a Pro

Who is Most at Risk for Long-Covid?

A meta-analysis revealed the risk factors for long-covid: being female, obese, over 40, a smoker, and having previous medical conditions. Who Is Most At Risk for Long Covid? (gift article)

032 - Bayesian Thinking, Cadavers, and Medical Unions - HealthHippieMD Week In Review

House Staff Local 131

I read an article about physicians unionizing. Although there has been talk about this for quite some time, I did not realize it had already happened in several locations: Doctor Unions Are Good for Your Health

Avatar Now

What do you get when you combine the immersive collaborative experience of an escape room with a video game? You get a Gamebox. Immersive Video Games Are Coming to a Theater Near You

The Plant Whisperer

Are plants sentient? I'm still not convinced, but this scientist theorizes they might be. What Plants Are Saying About Us - Nautilus

Spring Ahead

I read an article from a sleep scientist about the downsides of Daylight Savings time. The report convinces us that we should be on a permanent Standard Daylight schedule, not a permanent Daylight Savings schedule, as is currently suggested in a Congressional Bill.Springing forward into daylight saving time is a step back for health – a neurologist explains the medical evidence and why this shift is worse than the fall time change

Swiss Miss

The iconic Matterhorn of the Swiss Alps will no longer be seen on the wrappers of Toblerone chocolate bars after production moves from Switzerland to Slovakia. Where are Toblerone chocolate bars made?

Taking Control of What you Read on the Internet

Here is an article on the 25-year-old technology, RSS feeds: It's time to take back control of what we read online. I use RSS feeds in various ways. For my daily news, I rely on Feed Bin and Unread. I previously wrote about the ways I use RSS in scholarly activities: Unlock the Power of RSS feeds with DEVONthink — Workflows in Personal and Professional Productivity

This is your Brain on Art

"Art is not a luxury for our downtime, but an important contributor to physical and mental well-being..." I couldn't agree more, especially regarding music. How art, music, and dance affect your brain and body. (gift article)

Non-Nutritive Sweeteners

Artificial sweeteners are in various foods, from bread and cereal to tortillas and greek yogurt. Here is an article on the dark side of sugar substitutes: How sugar substitutes sneak into foods and affect your health (gift article)

Healthy, Redefined

The FDA is cracking down on commercial foods that may be labeled 'healthy.' The food companies are resisting: FDA is redefining 'healthy,' and the food industry is pushing back (gift article)

Personality Testing in the Workplace

Many years ago, I went down the rabbit hole, taking any personality test I could get. Although many personality tests (i.e., MBTI) have not been validated, they are increasingly used to make workplace decisions. Personality testing is now a $2 billion industry. The $2 Billion Question of Who You Are at Work (gift article)

The Argument for Moving Closer to Your Friends

"Many people are prepared to move for a new job, to be with a romantic partner, or even just for an adventure. Moving to be closer to buddies should be no different. Friends are not incidental to a good life; they're essential to one. So why not shorten the distance between you and them?" Live Closer to Your Friends

Health Podcasts Worth Listening To

....at least according to the NY Times. I am going to check out a few of these: Here Are 12 Health Podcasts Worth Listening To (gift article)

What Fuels Teen Anxiety?

Reformers have argued for fewer hours in a workweek. Yet, simultaneously, demands on our children at school have increased. Many believe the time needed to become attractive college applicants at the root of teen anxiety: "Richer and more complex economies require more rigorous and intense education, putting more pressure on kids to be high-achieving perfectionists." We're Missing a Key Driver of Teen Anxiety

Does your Microbiome Influence Interest in Exercise? (pre-clinical)

An interesting article in WaPo about how, in mice, the microbiome influences interest in exercise: How your microbiome may influence your motivation to exercise - The Washington Post (gift article)

Cannabis and Anesthesia

An article in the Economist discusses how cannabis influences the amount of drugs needed for adequate anesthesia. Cannabis and anesthesia do not mix

A Short History of Medical Cadavers

Medical students traditionally dissect cadavers while learning anatomy. Ever wonder where the bodies come from? From grave robbing to giving your own body to science – a short history of where medical schools get cadavers "Where many Americans once regarded medical students as "butchers" for exploiting their beloved dead, contemporary students honor what some of these future doctors call their "first patients" for the precious gift they have been given."

Bayes' Rule

After seeing all the evidence, how strongly should you believe something? That question is at the heart of Bayesian thinking, named after the Reverend Thomas Bayes. Here is an interesting video explaining Bayes Rule: Harvard professor explains Bayes' rule and an interesting article on how to use Bayesian Thinking to influence our relationships: Bayes and Deadweight: Using Statistics to Eject the Deadweight From Your Life.

025 - Chronobiology, Anticipation, Cancer Dietary Choices - HealthHippieMD Week In Review

One Question to Boost Your Longevity and Well-being

Having something to look forward to has many health benefits: Asking yourself one fun question could help boost your well-being and longevity.

A Simple Dietary Swap to Improve Health

The new year is a time to examine our habits. If you've resolved to improve your diet, here is a simple yet effective way to improve the quality of your food: For weight loss, replace processed foods with healthy, fiber-rich carbs. (gift article)

Chrononutrition

Another article from WaPo on why you should front-load your calories early in the day: Why timing big meals early in the day is better for your health. (gift article)

Chronobiology and Chronotherapy

Scientists are slowly learning the importance of timing of oral medications: Timing matters for medications – your circadian rhythm influences how well treatments work and how much they might harm you. Yet, the FDA recognizes the importance of timing in only a few medications: Dosing time matters | Science.

New Study Demonstrates Association between Healthy Eating and Reduced Mortality

JAMA published a study demonstrating the association between healthy eating and decreased mortality this week. Although the investigation suffers from the traditional caveats of nutrition research (food diaries, etc.), it differentiates itself by the size of the cohort and the length of follow-up (36 years). Healthy Eating Patterns and Risk of Total and Cause-Specific Mortality.

The Psychology of Procrastination

If one of your resolutions is to procrastinate less, here is an article to help you understand how to overcome inertia: What causes your brain to procrastinate and how to face it. (gift article). One of my favorite internet sites, Wait but Why, also has a series on procrastination:

• Why Procrastinators Procrastinate — Wait But Why
• How to Beat Procrastination — Wait But Why
• The Procrastination Matrix — Wait But Why^a26c07

ZOE Nutrition

Tim Spector founded a personalized nutrition company and wants you to know why: Go with your gut: scientist Tim Spector on why food is not just fuel. The test is a bit expensive but is likely a harbinger of nutritional trends to come.

The Daily Habits of Happiness Experts

The people that study happiness have some valuable habits we can all learn from The Daily Habits of Happiness Experts.

England Bans Single-Use Cutlery

In an attempt to reduce pollution, England has banned single-use items such as plastic cutlery, plates, and trays. England Will Ban Single-Use Cutlery and Plates.

Scientific Stagnation

This year, a new study, Papers and patents are becoming less disruptive over time, reported any given paper today is much less likely to become influential than a paper in the same field from several decades ago. Science Has a Crummy-Paper Problem - The Atlantic

Hearing Aids and Cognition

Restoring hearing was linked with less long-term cognitive decline, a recent systematic review and meta-analysis showed: Use It, or Lose It: Hearing Aids Linked to Cognitive Benefit.

Cancer and Diet

Michael Greger has a great series of videos on food and cancer. In the latest, he offers his thoughts on what you should (and shouldn't) eat if you've already been diagnosed with cancer: The Best Diet for Cancer Patients.

How Music Casts its Spell on Us

Another excerpt from the book, Awe: The New Science of Everyday Wonder and How It Can Transform Your Life. The article The Neurophysiology of Enchantment: How Music Casts Its Spell on Us, discusses the neurophysiology of music appreciation. +Jeff Beck, one of the greatest guitarists of all time, passed away this week. The NY Times published a list of his ten essential songs: Jeff Beck's 10 Essential Songs (gift article)

Covid and the Immunocompromised

Although most Americans seem done with Covid and Covid precautions, the risk is still high for those of us that are immunocompromised. Here is an opinion piece on how society could protect its vulnerable citizens: Opinion | We need to do more to assist the immunocompromised. (gift article)

009 - Doritos Dementia, Pain Clocks, and Forest Bathing - HealthHippie Week In Review - September 11, 2022

Random Acts of Kindness

Prosocial behaviors are good for you and the recipient of your generosity. The article, The Unexpected Power of Random Acts of Kindness, talks about the phenomenon. I learned that many underestimate how much the receiving party appreciates a small act of kindness.

Compassion

Empathy, the ability to feel someone else's pain and take on their burdens, is a valued trait in society. There is evidence that empathy comes at a cost. Instead, we should strive for compassion. Are You Empathetic? Try Compassion Instead. discusses the differences between empathy and compassion and offers practical advice on how to cultivate compassion in one's life.

Building a Simple Life

The article, 5 rules to build your version of the simple life, offers some helpful advice on how to decrease complexity day-to-day and live a better life. "By dedicating yourself to less, you do those things better. What activities and pursuits you decide to cut should result from a long, honest self-examination of the things that are important and meaningful to you." I've touched on many of the topics covered in the article: Dark Horse: Purpose, Fulfillment, Success (and Ikigai), Time Poverty: a significant threat to wellness, and ZigZag Project - ZigZag Podcast.

Mucus, Slime, and Snot

The article, Slime keeps appearing in nature and scientists are just starting to figure out why, discusses the ubiquity of this biological product of proteins and sugars found everywhere, from our saliva to snail trails.

+More on snot: The Science Behind Why We All Have Snot

Immortal Jellyfish

The article, This Jellyfish Can Live Forever. Its Gene May Tell Us How, was interesting. The report covers the research into why the jellyfish, Turritopsis dohrnii, is essentially immortal. Although scientists doubt there is generalizability in humans, the study is interesting nonetheless.

Optimizing Forest Bathing

Numerous scientific studies reveal the physiological and psychological benefits of time spent among trees. Japanese doctors go as far as prescribing "forest bathing:" Take a Walk in the Woods. Doctor's Orders There is not yet an understanding of how different kinds of treescape affect us. Scientists Are Unlocking the Secrets of Why Forests Make Us Happy, focuses on some of the issues. The article does not mention the microbiome. The microbiome is involved in mood: Gut Feelings: The Role of the Microbiome in Behavioral Health. I've often wondered if the inhaled and ingested products of the forest (bacteria, fungi, etc.) play some role in the beneficial effects of nature on physiology and psychology. I'm willing to bet they do. Give me a holler if you're interested.....

Measuring Emotional Intelligence

Emotional Intelligence positively influences health, relationships, and how well one does personally and professionally. Some research suggests people with emotional intelligence have enhanced resilience to stress. Interestingly, scientists cannot agree on a definition of emotional intelligence. A unified theory of emotional intelligence is important because the theory determines what must be measured. Emotional intelligence might make you more resilient, but there's a catch.

Are we in a Psychedelic Bubble?

The Wired article, Is the Psychedelic Therapy Bubble About to Burst, , offers an alternative view to the current hype surrounding psychedelics. The report is well worth the read.

Synthetic Microbiomes

An article on a Stanford group that successfully developed a stable microbiome when transplanted into bacteria-free mice: Scientists Have Made a Human Microbiome From Scratch. The article summarizes the recent manuscript published in Cell: Design, construction, and in vivo augmentation of a complex gut microbiome. I have yet to read the paper, but the initial thought that grabbed me was questioning how generalizable this tool could be. The assemblage of microorganisms in the gut microbiome has many interdependencies. Thus, if even a single resident ordinarily present in the gut is missing in the model, any conclusions reached could be erroneous. I hope this is used as a research tool, not just a way to cash in on the microbiome gold rush.

Cognitive Biases, Brain Biology, and Stubborn Minds

"People form opinions based on emotions, such as fear, contempt, and anger, rather than relying on facts. New facts often do not change people's minds." Cognitive biases and brain biology help explain why facts don't change minds, is an interesting article that gives some insight into biology and psychology of polarized thinking.

Science-Backed Friend-Making

I've enjoyed a new podcast find, Healthier Together (except for the advertisements). Making friends as an adult is hard. The recent episode, Science-Backed Secrets For Making Friends As An Adult with Dr. Marisa G. Franco, offered many insights and tips. The interview, along with a recent article prompted me to purchase Dr. Franco's book, Platonic: How the Science of Attachment Can Help You Make--and Keep--Friends I'll let you know what I think.

+More on making friends as an adult (listen to this first): The Secret to Making Friends as an Adult.

The Pain Clock

We have known patients experience increased pain at night, which was assumed to be due to sleep deprivation. But a recent small study, Circadian rhythmicity of pain sensitivity in humans, hints that the periodicity may be due to circadian rhythms. The study's findings are summarized in Why Pain Feels Worse at Night. Although the study was small and performed only in men, it offered plenty of food for thought.

Doritos Dementia

Yet another reason to put aside processed food in favor of whole plant-based foods. The article, More Evidence Ultraprocessed Foods Detrimental for the Brain, summarizes a recent study presented at the Alzheimer's Association International Conference. The study showed that a higher intake of highly processed foods was associated with a faster executive and global cognitive function decline. _"Participants who reported consumption of more than 20% of daily calories from ultra-processed foods had a 28% faster rate of global cognitive decline and a 25% faster decrease of the executive function compared to those who reported eating less than 20% of daily calories from ultra-processed foods." _

Quote of the Week

"Real change, enduring change, happens one step at a time." — Ruth Bader Ginsburg

003 - Mad Honey, Frisson, and Psychedelic Capitalism - HealthHippie Week In Review - July 31, 2022

1. High on Honey

I had never heard of "Mad Honey." The article Can mad honey get you high? A bee expert reveals the answer. The psychoactive ingredient in Mad Honey is Grayanotoxin, a neurotoxin that works by changing sodium-gating in cells. Mad Honey is produced in Nepal and Turkey, but Mad Honey Disease (intoxication with Mad Honey) is seen worldwide thanks to the Dark Web. Mad Honey is used as an aphrodisiac to treat various GI ailments and hypertension.

2. A Walk in the Park

I came across an article from 2018, The Secret to Good Health May Be a Walk in the Park - The New York Times The connection between parks and health is well established, but I learned quite a few things. The rankings have changed since the article was written in 2018. This year, Washington, D.C was rated #1. North Carolina does not fare well for its beauty and open space. Raleigh, NC's top park city, is #50 in the top 100 metropolitan areas. Explore your city's rank with the ParkScore Index.

3. Umami

A brief overview of the fifth taste, Umami: Umami: You never say its name, yet you taste it every day - Big Think

4. The Microbiome and Longevity

I found an interesting press release from 2017, Gut bacteria might one day help slow down aging process, and I had to learn more. So I downloaded the paper, 'Inside Out'- a dialogue between mitochondria and bacteria - PubMed. Most of the work focused on observing the role of Colanic Acid, an E. Coli derivative, in the aging process of worms. The longevity boost appeared mediated through the mitochondria (the powerhouses of each cell). The authors were hopeful the finding would translate into humans as Colanic Acids work similarly in worms, fruit flies, and cultured mammalian cells.

5. Circadian Rhythms and Exercise

There is an age-old debate about the best time of day to exercise. Your body has an internal clock that dictates when you eat, sleep, and might have a heart attack – all based on time of day describes some pre-clinical work to answer this decades-long debate.

6. Psychedelic Capitalism

There is a gold rush when a paradigm-shifting discovery arrives in medicine. So it is with the (re)emerging domain of psychedelics. The article The High-Stakes Race to Engineer New Psychedelic Drugs, focuses on one of the prominent (controversial) companies in the new psychedelic race, Compass Pathways, and its star chemist, Jason Wallach.

7. Music and Pain Relief (Music-Induced Analgesia)

Anything that mentions music and medicine catches my eye. I read Why does music numb physical pain? Scientists uncover clues . The article summarizes the findings in Sound induces analgesia through corticothalamic circuits recently published in Science. In mice, several types of Sound, pleasing (at least to humans, unknown in mice), discordant, and white noise, all seemed to influence pain perception similarly through modulation of thalamic circuitry. I plan to pay close attention to the emerging studies of music-induced analgesia.

8. Oura adds Blood Oxygen Sensing

I wrote about my love for my Oura Ring. This week, Oura is rolling out night-time oxygen sensing. Third-generation rings will measure blood oxygen and breathing regularity, both impaired with serious health problems such as sleep apnea and/or lifestyle choices such as alcohol before bedtime. The addition of the new variables "provide a more comprehensive assessment of sleep health and physiology." I'm a fan, except the new feature significantly impacts how often I have to recharge my ring.

9. How to Read Effectively

I love the Farnum Street newsletter, blog, and podcast. The host, Shane Parrish, never disappoints in his thoughtfulness and approach to topics. It is a rare week I don't learn something from him. I found this video on YouTube, How to Become a Better Reader (read less, learn more). The video is a brief overview of HOW to read. Here is the FS blog entry on the same topic. If you'd like to learn more about extracting and retaining knowledge, the book How to Take Smart Notes: One Simple Technique to Boost Writing, Learning, and Thinking is a classic. I've always been more digital than analog and am enamored with Personal Knowledge Management (PKM) software to keep track of notes. I'm especially fond of Obsidian and DEVONthink. For more on idea generation and knowledge management, please see Zettelkasten Management 2022 using Obsidian, Drafts, and Devonthink and my other entries at wippp.com.

10. Rethinking Alzheimer's

For as long as I remember, toxic proteins have been thought to cause Alzheimer's Disease. But recently, scientists contend our understanding of the disease is at best incomplete and at worst wrong: We might have Alzheimer's all wrong.

11. Follow the White Light

The article, After death, you're aware that you've died, say scientists, was the strangest I read this week. Scientists studying Near-Death Experiences (NDE) try to explain the common phenomenon reported by those that die and are resuscitated. Although the mechanisms are unclear, these scientists believe we remain conscious for up to 20 seconds after our breathing and hearts stop. The article also mentions a study in rats that showed a surge of electrical signals moments before brain death. I saw something similar in a case in the OR. Our original observation during organ donation prompted this case study: Processed Electroencephalogram During Donation After Cardiac Arrest.

12. This Playlist is Scientifically Verified to Give you Chills

Most of us have had a feeling of "frisson" (the sense of hair raising on the back of the neck) when listening to music, observing beautiful art, hearing poetry, or viewing brilliant scenes in nature. The article Frisson: This playlist is scientifically verified to give you chills, discusses the phenomenon in depth and includes a link 715 Songs to Give you Frisson I'm slowly working my way through.

+This band consistently gives me Frisson-Echo Sessions 63 - Dirtwire - Full Show

+Another fascinating article discussing how personality type influences musical preference: Your music preferences reveal your personality traits.

13. Akkermansia Muciniphilia

For the duration of my almost 20-year fascination with the microbiome, certain bacteria keep popping up. One of the bacteria that seem to be continually in the literature is Akkermansia muciniphilia. A. mucinophilia appears to play a critical role in immunity and immunity homeostasis. It has purported roles in obesity, inflammatory bowel disease, diabetes, and cancer immunotherapy efficacy. The manuscript, Akkermansia muciniphila phospholipid induces homeostatic immune responses is the latest article I've read on the biochemistry involved in immune regulation.

001 - Friendship, Psychedelics, and Maggots, Oh My - HealthHippie Week In Review - July 17, 2022

You may have noticed the difference in format this week. Starting today, I will send a weekly curated newsletter with interesting articles, videos, and audio from the week. I will reserve blog entries for longer-form writing, such as the following past articles:

• What are Short-Chain Fatty Acids, and how do they impact my health?
• Are Probiotics Making You Fat? probiotics, prebiotics, and fermented food
• Dark Horse: Purpose, Fulfillment, Success, and Ikigai
• Time Poverty: a significant threat to wellness

Thanks for reading and your suggestions. Please grow my audience by forwarding this email to at least one friend and encouraging them to subscribe.

Thanks for your support!

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Here are some of the interesting items from this week.

On Friendship and Living Well

The Friendship Files - The Atlantic presents an out-of-the-box method to finding deep friendship, similar to an arranged marriage, complete with rituals and renewal of vows. The article made me think of another I had read about Aristotle's virtues and how to live a good life: How to be happy: Aristotle's 11 guidelines for a good life.

Maggot Therapy

This week's Science Friday featured a previous story on Maggot Therapy and an update. Science Friday: Big Bang Debate History, Black Hole Sounds, Maggot Healthcare, Forest Lichens. July 8, 2022, Part 2 on Apple Podcasts The history of the discovery of maggot's medicinal use is fascinating (it turns out larvae secrete antibacterial, antifungal, antiviral and pro-healing compounds). Listening to the story and reading about the history, The Biochemistry Of Medical Maggot Spit, made me think of some of the observations of Florence Nightingale (who observed that soldiers exposed to the fresh air and sunlight after being wounded, actually had better outcomes) Open hospital windows to stem the spread of infections, says microbiologist.

Mental Illness, Psychedelics, and Psychiatry

Currently, many eyes (both clinical and on Wall Street) are focused on the emergence of psychedelic-assisted psychotherapy. I've added Netflix's new docuseries, How to Change Your Mind, to my viewing queue. The series is adapted from Michael Pollen's excellent book of the same name. As I read another article, Will We Ever Find a Cure for Mental Illness? - The Atlantic, that reviews a new book by Andrew Scull on the history of psychiatry, Desperate Remedies.

Antibiotics and Mental Health

I read an interesting story about a study that claims a single dose of antibiotics correlates with altered emotional processing in young adults - Antibiotic Treatments May Make Us More Susceptible to Negative Emotions - Neuroscience News. I have yet to read the actual manuscript currently in pre-press, but I find fascinating the emerging focus on the gut-brain axis and its influence on mental health. The microbiome is the new frontier in diagnosing and treating mental illness. Last year, I delivered a Zoom lecture on the topic - Gut Feelings: the role of the microbiome in behavioral health — HealthHippieMD

The Brain's Low Power Mode

Much like our electronic devices, pre-clinical studies suggest the brain has a low-power mode that kicks in when energy is in short supply. This interesting article, The Brain Has a 'Low-Power Mode' That Blunts Our Senses covers the findings in the recently published paper, Neocortex saves energy by reducing coding precision during food scarcity. In short, the visual cortex conserves energy by altering the firing of neurons in the visual pathways. The power down-regulation could be switched off by administering Leptin. The influence of Leptin, a hormone usually thought of in a food-seeking context, not visual pathways, is another example of how our bodies are an extensive, complex, integrated system. The far-reaching effects of hormones should also be a warning that manipulation of single pathways of our complex physiology can have unintended consequences-there are still many unknown unknowns in human physiology and biochemistry.

Circadian Medicine

It seems everywhere I look, I see a story or study about the body's circadian rhythms. I read two articles this week on the topic: Clocking the Drugs, Drugging the Clock: The Health Impact Of Circadian Medicine. and One kind of work interferes with metabolic health Most are aware of the central master clock, but as with everything in the body, the story is much more complicated. Every organ, and likely every cell, has an intrinsic physiological clock. As with many processes in the body, the influence is bidirectional. For instance, circadian rhythms affect the composition of the microbiome, and the microbiome composition affects circadian rhythm. Current studies are investigating the impact of circadian rhythms on health, cancer treatment, and a whole host of other applications. One thing is growing increasingly clear: there is likely an optimal time to eat, sleep, and take medications/supplements. One kind of work interferes with metabolic health discussed the various health effects of working at night. There is an association between night work and obesity, cancer, and diabetes. The article made me wonder if nighttime workers should be offered hazard pay since night shifts negatively impact health and well-being.

NCCIH Free ebook on Yoga

The National Center for Complementary and Integrative Health published a free ebook about Yoga. The ebook provides an overview of the Science behind the benefits of Yoga, information on how to practice Yoga safely, and a summary of national survey findings about the use of Yoga in the United States. Yoga for Health (eBook) | NCCIH

Intermittent Fasting and Covid

Late in the week, I read this news release, Study finds people who practice intermittent fasting experience less severe complications from COVID-19! and the paper it cites, Association of periodic fasting with lower severity of COVID-19 outcomes in the SARS-CoV-2 prevaccine era: an observational cohort from the INSPIRE registry | BMJ Nutrition, Prevention & Health. Although there are many obstacles to the generalizability of the study (non-randomized study population, self-selection for database inclusion, self-reported fasting activity, etc. ), the paper includes many thought-provoking hypotheses on how fasting might influence COVID outcomes.

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