054 - Cheating Death, Ultralearning, and Harmonious Disputes - HealthHippieMD Week In Review

Cheating Death

In the article How Old Can Humans Get? - Scientific American, scientist João Pedro de Magalhães speculates on extending human lifespans to 1,000 years through genetic alterations. By studying the genomes of long-lived animals, Magalhães envisions reprogramming aging at the cellular level, envisioning a future where humans could defy their genetic "software" to delay or reverse aging. Though practical challenges remain, Magalhães' geroscience insights prompt consideration of profound interventions that might extend human lifespans far beyond the present norm.

Books to Enhance Creativity

The Economist published a list of books on fostering creativity: What to read to become more creative

Ultralearning

On my quest to learn to play the guitar, I came across multiple mentions of the book Ultralearning: Master Hard Skills, Outsmart the Competition, and Accelerate Your Career. Although I bought the book in 2019, I have yet to dig in. Ultralearning is now on top of my "to read" pile.

Scentinel Health

Smell's connection to memory and emotion is being recognized anew, as studies reveal its crucial role in detecting brain diseases early. Loss of smell, or hyposmia, has emerged as an indicator of neurodegenerative disorders such as Parkinson's and Alzheimer's, even including conditions like Huntington's disease and multiple sclerosis. Researchers propose that olfactory bulb neurons, responsible for smell processing, could play a role in the early stages of brain diseases. Beyond disease prediction, smell also correlates with overall health and mortality risk, making the nose a potential health "scentinel." Why Loss of Smell Can Be an Early Sign of Brain Diseases Like Alzheimer's.

Constipation Linked to Cognitive Decline

New research from AAIC 2023 suggests chronic constipation, infrequent bowel movements, may indicate cognitive decline. Individuals facing such constipation exhibit cognitive aging equivalent to three years, with a 73% higher likelihood of subjective cognitive decline. This groundbreaking study highlights the interconnectedness of gut health and brain function, encouraging discussions about constipation and its management to mitigate dementia risks potentially. Studies exploring the relationship between gut bacteria and Alzheimer's biomarkers reveal intriguing connections, paving the way for novel therapeutic avenues. Constipation Associated with Cognitive Aging & Decline | alz.org

Unraveling Traveler's Constipation

Why do trips lead to constipation? The phenomenon is "traveler's constipation," which affects approximately one in three individuals, disrupting regular bathroom habits. Dehydration, immobility during flights, changes in sleep routines, and shifts in eating habits contribute to the issue. Scientists suggest staying hydrated, exercising, and incorporating fiber-rich foods like fruits and vegetables to prevent constipation. Hydrating foods, adjusting sleep schedules, and managing alcohol intake can also help. Why Do I Get Constipated When I Travel? - The New York Times

AI Enabled (Travel) Lists? Yes, Please

A new app, Soka, caught my attention. I spent the morning generating automated local and international lists of things I'd like to do, see, and eat. Söka: An AI Assisted App to Track Your Bucket Lists

Obesity Drug Reduces Heart Risks

The obesity drug Wegovy has demonstrated a 20% reduction in serious heart problems in a recent clinical trial, potentially pressuring insurers to cover the treatment. This trial marks the first to reveal that obesity drugs like Wegovy can enhance heart health, reinforcing the link between obesity and medical risks. The findings, as yet unpublished in a peer-reviewed journal, may encourage insurers to support the treatment, despite its high cost. Wegovy's capacity to improve patients' lives and medical outcomes could change the perspective on treating obesity, emphasizing aggressive intervention. Wegovy Cuts Risk of Heart Problems, Novo Nordisk Trial Says - The New York Times

The Healthy Info Pitfall

While HIPAA (Health Insurance Portability and Accountability Act) covers medical institutions' data security, personal health data collected at home isn't protected. Wearable trackers and health-related apps fall outside HIPAA's umbrella, putting users at risk. Patients must remember that individual-generated data isn't secure under HIPAA. What Doctors Wish You Knew About HIPAA and Data Security | WIRED

Grain Brain (mice)

A study by University of Otago researchers reveals that wheat gluten consumption triggers brain inflammation in mice, with potential implications for humans. While prior research linked gluten to weight gain and inflammation in the digestive system, this study identifies the first-ever connection between gluten and brain inflammation in the hypothalamic region, which regulates metabolism. Though the exact mechanism remains uncertain, this discovery raises concerns about long-term effects, including weight gain, blood sugar disruption, and memory impairment. While not advocating a blanket gluten-free diet, the findings suggest avenues for future research in human health. Wheat Gluten Spurs Brain Inflammation - Neuroscience News

Colonic Sensation (mice)

In a groundbreaking study, Harvard researchers have distinguished five distinct sensory neuron types in the colon, shedding light on the gut-brain connection. These neurons transmit diverse signals to the brain, with some responding to gentle movements and others to intense sensations like pain. Mimicking neurons found in the skin, this discovery in mice suggests potential cross-organ function conservation. If confirmed in humans, the findings could revolutionize gastrointestinal treatments by targeting specific neurons and understanding how mechanical forces translate into nervous system signals. Untangling Gut Feelings: Revealing the Colon's Sensory Neurons - Neuroscience News

Harmonious Disputes

When disagreements arise between partners, unfounded assumptions can intensify arguments. Termed "unconscious storytelling," this phenomenon involves imagining what the other person is thinking or feeling. Instead, renowned family therapist Terrence Real suggests using "the feedback wheel," a concise four-sentence method for sharing perceived slights. The phrases include describing facts of the situation, sharing your perspective, expressing emotions, and stating what would help. Shifting from anger to vulnerability fosters effective communication and promotes relationship repair. Fighting With Your Partner? Use These 4 Phrases - The New York Times

What Are Functional Foods

Here is an excellent article on functional foods: Does an apple a day keep the doctor away? A nutritionist explains the science behind 'functional' foods

053 - Scienceploitation, Successful Psychopaths, and Swedish Death Cleaning - HealthHippieMD Week In Review

Scienceploitation

The wellness industry is flooded with products making dubious claims, relying on fake science to deceive consumers. Brands use scientific-sounding buzzwords for marketing unproven products, exploiting emerging areas of science. Buyers seeking scientific evidence are often overwhelmed with confusing options. Vague terms like "boosts" and "supports" suggest positive health outcomes without clear definitions. Questionable studies and jam-packed ingredient lists further confuse consumers. Without strict monitoring, consumers must learn to assess claims, verify reputable sources, and be cautious of "too good to be true" promises in the pursuit of wellness. How to Spot False Claims in Your Wellness Products - The New York Times (gift article)

We Are Already Paying the Cost of Universal Healthcare

Here is an interesting opinion piece in the NY Times on the economic feasibility of universal healthcare: Opinion | Fixing Health Care Starts With the Already Insured - The New York Times (gift article)

On Boundaries

The article, No One Knows What Boundaries Are, explores the concept of boundaries and how it is often misunderstood. The piece delves into the cultural and generational factors contributing to the struggle to set and enforce boundaries. While boundaries are increasingly discussed in popular psychology, the article emphasizes that they are not rules for others but rather a personal yardstick for comfort and self-preservation. The true test of boundaries lies in how individuals respond when others violate them, and it highlights the importance of maintaining healthy relationships while respecting personal boundaries.

GenerativeAI for Music

Meta's new AI-powered tool is like Dall-E but for music discusses Meta's new sound generators that include music and effects. Right now, these tools are only available for research. I can't wait until they are publicly announced so I can take them for a spin.

Successful Psychopaths

While psychopaths are often associated with Hollywood villains, researchers are shedding light on a less-known aspect: "successful psychopaths." These individuals possess psychopathic tendencies but manage to avoid trouble and even excel in certain areas due to their unique traits. A dimensional approach has replaced the binary view, with boldness identified as a crucial factor alongside meanness and disinhibition. Though controversial, some argue that certain psychopathic traits can be advantageous in fields like business. Understanding these traits using new scales may help debunk stereotypes and discover the hidden potential of those who possess them. The Psychopathic Path to Success - Nautilus

Personality and Dementia Risk

A study examining nearly 2,000 individuals revealed a significant link between personality traits and the likelihood of developing dementia. Researchers found that individuals with higher levels of conscientiousness were less likely to experience cognitive decline, while those with neurotic tendencies were more prone to it. The study highlighted the role of personality traits in influencing the transitions between different cognitive statuses. While personality can influence the progression of minor or moderate cognitive impairment, it appears to have less impact once dementia sets in. Understanding these links could offer valuable insights into dementia prevention and management. Your personality is linked to risk of dementia - Big Think

Weighing the Evidence: Exercise and Weight Loss Debate

The global fitness industry is booming, and many exercise to lose weight—however, a debate in the scientific community questions whether exercise truly helps with weight loss. The constrained total energy expenditure hypothesis suggests the body compensates for activity by burning fewer calories outside workouts. While some evidence supports exercise-induced weight loss, other studies indicate that exercise may not prevent weight regain after dieting. The mixed findings suggest that exercise provides numerous health benefits, but its direct impact on weight loss remains uncertain. Exercise may or may not help you lose weight and keep it off – here's the evidence for both sides of the debate

The Art of Swedish Death Cleaning

"Rather than making do with less, it's about getting more from the things that make you happy." How Swedish death cleaning works to declutter your life (gift article) discusses the concept of "Swedish death cleaning," a method of decluttering and reevaluating our relationship with possessions. Inspired by the book of Margareta Magnusson, the method encourages people to let go of unnecessary belongings, reduce their carbon footprint, and prioritize experiences over material possessions. By recognizing the stories we tell about our stuff, we can make decluttering easier, create a framework for future purchases, and find happiness in owning only what truly matters.

Free Will: The Key to a Happier Life?

In To Get Happier, Choose to Read This Column, Arthur Brooks delves into the philosophical debate about free will and its impact on happiness. Drawing on concepts from science fiction and philosophy, the article explores the mind-body problem and the existence of free will. While uncertainty remains, the article suggests that embracing the idea of free will can lead to greater life satisfaction and positive decision-making. Whether a firm believer or a skeptic, acting as if you have free will can bring positive changes in your life.

Fraudulent Scientific Research

Allegations of data tampering in a 2012 study on dishonesty, co-authored by prominent researchers Dan Ariely and Francesca Gino, have raised concerns about the extent of scientific fraud. The study, involving separate experiments, was retracted after suspicions of manipulated data. Recent revelations from the insurance company involved in the study indicate inappropriate data manipulation. The possibility of dual fraud in the same paper has experts bewildered, suggesting that scientific fraud might be more common than believed. The lack of systematic fraud detection and assumptions about researchers' integrity add to the unsettling uncertainty surrounding scientific research ethics. Did Francesca Gino and Dan Ariely Fabricate Data for the Same Study?

Microwaving Plastic

For the Love of God, Stop Microwaving Plastic | WIRED has me seriously considering replacing my SnapWare.....

052 - Genetic Judo, Young Blood, and Gray Hair - HealthHippieMD Week In Review

Age is Just a Number

As seniors face complex health decisions, age alone may not be the best guide. Medical associations and health groups are shifting to consider life expectancy when recommending screenings and treatments. With the average life expectancy of a 75-year-old being 12 years, online tools like the "Know Your Chances" calculator can estimate mortality and disability risks, providing valuable context beyond age. By incorporating factors like smoking history and health status, patients can make more informed decisions about their healthcare, ultimately improving outcomes and avoiding unnecessary treatments. A Number That Should Guide Your Health Choices (It's Not Your Age) - The New York Times (gift article)

Immune System Influences Behavior

A recent study found the immune system (at least in mice) plays a role in altering our behaviors, especially in response to allergic triggers. "We find immune recognition controls behavior, specifically defensive behaviors against toxins that are communicated first through antibodies and then to our brains." Our Immune System May Help Guide Behavior

Humata.AI: ChatGPT to Query Academic Manuscripts

If you rely on academic publications for your work, prepare to have your mind blown. With Humata.AI,, after uploading a pdf of a manuscript, you can ask questions about the content or ask questions about a folder full of articles in aggregate. It worked incredibly well in the manuscripts I tried. My only complaint about this nascent tool was the limited ways to interact with the content, but I'm sure features will expand as the tool matures. Humata.ai worked much better in my experimentation than another tool I tried, Liquidtext. I suspect the field will get increasingly crowded with science-aware chatbots. Humata.AI is free for the first 60 pages of content, $15/month for more.

Using ChatGPT to Improve Your Writing

Large Language Models, like ChatGPT, are helpful in various ways for writing. Here are some ideas: 5 Ways ChatGPT Can Improve, Not Replace, Your Writing +And here is an article about using ChatGPT in medical diagnosis: A Mystery in the E.R.? Ask Dr. Chatbot for a Diagnosis.

Yo-Yo Diet Industry's Latest Spin

The weight loss industry is witnessing a new wave of reinvention as Americans continue their yo-yo relationship with dieting. Diet apps like Noom and WW (formally WeightWatchers) are now adopting a psychological approach to weight loss, emphasizing self-acceptance and joyful movement. Recently, Noom and WeightWatchers have integrated GLP-1 obesity drugs like Ozempic into their services, acknowledging that medications can be crucial in achieving good health for many. This shift reflects the desire to lose weight, though the approach has evolved from moralizing to a more attainable, value-neutral goal. The Diet Industry Is Pivoting to Ozempic

Unraveling the Mystery Behind Graying Hair

Gray hair is a visible example of how genetics and aging interact. Hair gets its color from melanin, a natural pigment produced by melanocytes. As we age, stem cell melanocytes can become trapped, leading to gray hair. Stress may also play a role in graying. While there's no reliable way to prevent or reverse gray hair, recent research suggests some intriguing possibilities. Why Does Our Hair Turn Gray? The Science of Aging Hair, Explained

Health System Monopolies

The NY Times published an opinion piece on healthcare monopolies: Opinion | The Ridiculous Medical Bill Brought to You by the Latest Hospital Merger - The New York Times (gift article). Hospital mergers and consolidations have created monopolies in the healthcare system, leading to decreased patient choice, rising prices, and limited innovation. The Biden administration has attempted to address the issue with antitrust activity, but hospital mergers have proven harder to curb compared to other industries. The Federal Trade Commission faces challenges blocking hospital mergers due to lengthy analysis and limited resources. Vertical mergers, where extensive hospital systems acquire smaller ones or doctors' practices, further exacerbate price increases. States are now considering price regulation as a possible solution to rein in the power of giant health systems.

Learning on Vacation

In this article, Arthur C. Brooks explores a vacation model often overlooked—turning leisure into learning. Research suggests that pursuing intrinsic interests and learning something new enhances well-being, even if it involves some sacrifice. By focusing on activities that captivate our curiosity, like taking a class or engaging in a guided retreat, vacations can be transformed into rewarding and content-filled experiences. So, instead of conventional models, consider turning your time off into an opportunity for personal growth and happiness. How to Have Your Most Fulfilling Vacation Ever

Young Blood Slows Aging (in Mice)

In a groundbreaking study, scientists extended the lifespans of older mice by connecting their blood vessels to younger mice, resulting in a 6 to 9 percent longer life for elderly rodents. Though not an anti-aging treatment for humans, the research suggests that compounds present in the blood of young mice may promote longevity. The experiment involved parabiosis, joining the animals together for an extended period, and upon separation, the aging process of the older mice appeared to have reversed, making them biologically "younger." Blood of Young Mice Extends Life in the Old - The New York Times (gift article)

Genetic Judo

"It's very cool. It turns something the cancer cell needs to stay alive into something that kills it, like changing your vitamin into a poison." Scientists at Stanford have developed a novel molecule that could potentially lead to groundbreaking cancer drugs. The molecule links cancer-driving proteins to cell-death genes, effectively turning the molecules promoting deadly growth into self-destruction triggers. In lab experiments, this dumbbell-shaped molecule was successful in activating cell-death genes in a blood cancer, diffuse large B-cell lymphoma. Flipping a Switch and Making Cancers Self-Destruct - The New York Times (gift article)

051 - Solace in Sorrow, Oxygen-Enhanced Learning, and Earworms - HealthHippieMD Week In Review

Finding Solace in Sorrow

The article, Good Grief: How to Make the Best of Painful Loss, delves into the realm of grief and offers strategies for coping with the loss of a loved one. Drawing inspiration from a Japanese "wind phone" that provides solace through one-sided conversations with the departed, the article delves into grief's psychological and physiological impact. Debunking the outdated stages of grief highlights the importance of finding meaning, embracing new identities, adopting rituals, and allowing oneself to experience happiness again. Moreover, it emphasizes the power of listening and being present to support those who are grieving.

A Breath of Fresh Air: Oxygen, Learning, and Stroke Recovery

Boost your brain: a simple 100% normobaric oxygen treatment improves human motor learning processes, published in Frontiers in Neuroscience, revealed that inhaling pure oxygen during motor learning tasks accelerated the learning process and improved performance in healthy individuals. The study indicated that oxygen supplementation could be a low-cost and low-risk approach to expedite stroke recovery. While the precise mechanisms behind the benefits of oxygen remain unclear, several new studies are in the works to learn more about this phenomenon. Pure Oxygen Speeds Up Learning. Can It Help Stroke Survivors Recover?

Britain's National Health Service

Although I believe a single-payer system is the only way out of our current healthcare crisis in the U.S. (exponentially higher costs and mediocre to poorer outcomes than our peers), other healthcare models worldwide suffer their own problems. The NY Times had an interesting article on Britain's National Health Service: A National Treasure, Tarnished: Can Britain Fix Its Health Service? - The New York Times (gift article)

Cancer and Family Dynamics

I Have Cancer. I Can't Put My Kids First Anymore is an interesting piece in the Atlantic on how serious illness affects traditional familial roles and relationships.

Weighing the Risks

Regarding weight loss, injectable medications like Ozempic and Wegovy can pose unique risks for older adults. As muscle loss accelerates aging, frailty and the risk of fractures become more significant concerns for individuals over 65. These drugs, which cause rapid weight loss, often reduce muscle mass, which can negatively impact overall health. Experts emphasize the importance of maintaining muscle mass through strength training exercises and protein consumption to mitigate these risks in older adults. Risks of Ozempic, Wegovy and Other Weight Loss Drugs for People Over 65 - The New York Times (gift article)

Unraveling Earworms

Wired explores the perplexing phenomenon of earworms—those catchy tunes that repeat in our heads. Delving into the science behind these musical intruders, the article examines the triggers of recency, familiarity, and boredom that make songs get stuck in our heads. With insights from experts, it unveils strategies to banish earworms, including completing the song, distracting oneself, diversifying playlists, and even mixing up the lyrics. Why Songs Get Stuck in Your Head—and How to Stop Them.

Privacy and Generative AI

Wired published an informative article on things to consider about privacy while using the new generative AI tools: How to Use Generative AI Tools While Still Protecting Your Privacy | WIRED

Private Equity Firms and Healthcare

Reading this article about equity firms buying physician practices made me feel sick: Who Employs Your Doctor? Increasingly, a Private Equity Firm. (gift article). And we wonder why there's a Moral Crisis of America's Doctors. (gift article).

The Neurophysiology of "I" and Me

Researchers have shed light on how the brain creates our physical sense of self. By stimulating a specific brain region known as the anterior precuneus, scientists caused individuals to experience feelings of floating, dizziness, and detachment from their bodies. This discovery, coupled with understanding the "me" aspect located in the default-mode network, brings us closer to comprehending the complexities of our self-perception. Further investigations may help treat conditions like depression and dissociation while explaining intriguing phenomena like out-of-body experiences. How the Brain Creates Your Physical Sense of Self.

Record-Breaking Temperatures: Climate Change?

The Economist weighs in: Are the current heatwaves evidence that climate change is speeding up?

Your Food and Climate Change

Curious about how the food you eat influences climate change? The NY Times has some answers: Your Questions About Food and Climate Change, Answered

Beyond's Plant-Based Meats and Heart Disease

Michael Gregor discusses plant-based meat and the SWAP Trial: Are Beyond Meat Plant-Based Meat Alternatives Healthy?

050 - Metformin for Long-Covid, Aging Gracefully, and Loneliness - HealthHippieMD Week In Review

Metformin and Long Covid

A recent study published in The Lancet Infectious Diseases reveals that metformin, a commonly used diabetes drug, may reduce the risk of developing long COVID by 41 percent for individuals who are overweight or have obesity. Long COVID, a condition characterized by persistent symptoms after a COVID-19 infection, has no approved treatment. The study's findings offer hope, but further research is needed to validate the results and explore how metformin prevents long COVID. Although the mechanism is unclear, unlike the authors, who opine that metformin may interfere with viral replication, I think a more likely explanation is that it modulates the immune system through its influence on the microbiome. A Common Diabetes Drug May Prevent Long COVID in Some People - Scientific American

Covid and the Introversion - Extroversion Dynamic

An interesting piece in WaPo about how Covid (permanently?) flipped the script in social dynamics: Opinion | The world has become more introverted. And I hate it. - The Washington Post (gift article)

How to Age Gracefully

A new study suggests that learning new skills can have significant cognitive benefits for older adults. The authors hypothesize that cognitive slowing as a senior is akin to the "summer slide" that schoolchildren experience (every year, teachers and parents observe how summer vacations lead some children's academic progress to backslide). What if the elderly experience a similar phenomenon? The research found that a three-month intervention program involving classes on various skills, such as singing, drawing, and language learning, improved participants' memory and attention. Surprisingly, the cognitive gains continued even after the program ended, with participants' abilities resembling those of individuals 30 years younger. Encouraging lifelong learning and creating enriched environments for older adults could enhance their cognitive skills and support healthy aging. To Stay Sharp as You Age, Learn New Skills - Scientific American

Consciousness Conundrum: Animal Awareness and Neural Correlates

Here is another story from the 26th meeting of the Association for the Scientific Study of Consciousness (mentioned last week). The article discusses the potential consciousness of vertebrates, cephalopods, and arthropods, with debates on their complex behaviors and brain structures. Additionally, the possibility of achieving conscious artificial intelligence and its ethical concerns were discussed. Thousands of species of animals probably have consciousness

How Susceptible are you to Misinformation?

A new test designed to measure susceptibility to misinformation reveals that younger Americans struggle more with identifying fake news than older generations. Researchers developed the "misinformation susceptibility test" (MIST) at the University of Cambridge in collaboration with YouGov. Participants were presented with authentic and AI-generated false headlines and had to differentiate between them. The study found that individuals who spent more time online and relied on social media platforms for news were more prone to falling for misinformation. Age and personality traits also played a role in susceptibility. While the test has some limitations, it underscores the importance of media literacy in navigating the information landscape. How Susceptible Are You to Misinformation? There's a Test You Can Take - Scientific American

Can Math and Physics Save an Arrhythmic Heart?

"Abnormal waves of electrical activity can cause a heart's muscle cells to beat out of sync."_ In Can Math and Physics Save an Arrhythmic Heart?, Flavio Fenton, an expert in cardiac dynamics, discusses ways to treat heart arrhythmias without resorting to painful defibrillators.

Weighing In: The Hidden Costs of Dieting

In the article Why You Don't Just Lose Fat When You're on a Diet Adam Collins explores the consequences of dieting beyond fat loss. While being in a calorie deficit helps shed weight, it also results in the loss of muscle mass. The depletion of glycogen stores leads to the release of water weight. Moreover, the body turns to metabolizing muscle tissue for energy, impacting metabolism and potentially causing weight regain. The article emphasizes the importance of exercise, protein intake, and sustainable lifestyle changes for maintaining muscle mass and preventing metabolic shifts during weight loss.

Ozempic: A Treatment for Addictive Behaviors?

This week, Scientific American published an article on a phenomenon I first mentioned in Newsletter 43. A surprising side effect of Ozempic, a diabetes drug that aids weight loss, has emerged: users report a reduction in cravings for addictive substances such as nicotine, alcohol, and gambling. Scientists are now investigating whether these weight-loss drugs, including Ozempic, can be used to treat addiction. Ozempic targets a hormone that regulates appetite and weakens the brain's Association between food and pleasure. Animal studies have shown promising results, but human trials are still limited. Researchers are initiating their studies to determine the safety and effectiveness of these drugs in addiction treatment. Could New Weight-Loss Drugs like Ozempic Treat Addiction? - Scientific American (Thanks Dave Pell, NextDraft)

The Epidemic of Loneliness

"Research has shown that a lonely brain is transformed. Neurotransmitters important for bonding and social connection go haywire. The hypothalamic-pituitary-adrenal axis, responsible for modulating stress, is hyperactive. The amygdala, which triggers our fight-or-flight response and helps process emotional reactions, is in overdrive: In previous studies, Dr. Cacioppo found that lonely people detect negative or threatening pictures and words in under 400 milliseconds. The neuroscience might explain the sadness that accompanies loneliness and the palpable sense of danger." The New York Times had an insightful piece on loneliness: Opinion | How to Treat Loneliness With Medicine. (gift article)

Psychedelics in the U.S. Defense Funding Bill

Lawmakers included funding in the National Defense Authorization Act to look at psychedelics' role in treating PTSD, depression, anxiety, and chronic pain. Psychedelics like MDMA play a part in US defense funding bill

049 - Collective Neuroscience, Biobanks, and Consciousness- HealthHippieMD Week In Review

The Problem with Biobanks

In today's biobank studies, your genetic information can provide valuable insights even with partial information. Researchers often use de-identified genetic data stored in biobanks for various studies, but the broad consent obtained from participants may not adequately inform them about the potential uses of their data. Recent research highlights that even non-response to survey questions can reveal information about a person's education, health, and income levels if genetic data is available. To ensure transparency and trust, improving informed consent processes is essential in leveraging biobanks effectively for health research. Researchers can learn a lot with your genetic information, even when you skip survey questions – yesterday's mode of informed consent doesn't quite fit today's biobank studies

Consciousness Showdown

In a packed auditorium, neuroscientists and philosophers eagerly awaited the unveiling of groundbreaking results from a two-decade-old bet. David Chalmers, a philosopher, and Christof Koch, a neuroscientist, had wagered on finding a neural correlate of consciousness within 25 years. As cutting-edge experiments shed light on the nature of consciousness, two leading theories emerged: the Global Workspace Theory and the Integrated Information Theory. A high-stakes trial pitted these theories against each other, with mixed results, leaving the search for a clear neural marker of consciousness unresolved. Nonetheless, a new bet has been placed, setting the stage for a fascinating future of exploration. 2 Leading Theories of Consciousness Square Off - The New York Times (gift article)

Climate Change and Salmon Farming

Chile produces more than half of the farmed salmon consumed in the U.S. Climate change is profoundly altering the industry...The Perils of Farming Salmon in a Warming World

Cracking the Case

In a groundbreaking study, researchers from Nanjing University and the University of Bristol have delved into the age-old question: "Which came first, the chicken or the egg?" Contrary to previous beliefs, scientists discovered that the earliest common ancestors of the Amniota family, which includes chickens, did not lay hard-shelled eggs. Instead, they either gave birth to live young or practiced extended embryo retention (EER), where the fetus develops within the mother for an extended period. These findings challenge the notion that the hard-shelled egg was essential for the evolution of terrestrial animals and shed new light on the complex process of animal reproduction and evolution. Which Came First, the Chicken or the Egg? Scientists Might Finally Have the Answer.

Fourth of July Food

In honor of the Fourth of July, here are some interesting food origin stories: Pink Lemonade's origin story begins with a disgruntled circus clown (gift article) and The Hamburger's origin story (gift article).

Whose "Fault" is Obesity

The Washington Post had an interesting opinion piece on responsibility for the obesity epidemic: Whose fault is obesity? Primarily the food industry. (gift article)

Ode to Dietary Fiber

"Limiting simple sugars and refined carbohydrates may improve certain aspects of metabolic health, as these are some of the most easily digested and absorbed calories. But a more sustainable and comprehensive way of improving health may be increasing the unprocessed, more complex, and slowly absorbed carbohydrates that come with their natural packages and instructions intact – those with fiber." Dietary fiber, which few Americans get enough of, is one of the keys to weight management. Fiber is your body's natural guide to weight management – rather than cutting carbs out of your diet, eat them in their original fiber packaging instead.

What To Do When You Can't Fall Asleep

What to Do When You Can't Fall Asleep May Surprise You - Scientific American has some good tips for those occasional nights of insomnia and when lack of sleep becomes a problem.

AI and Musical Hit Prediction

AI researchers claim to have found a link between the body's physiological response to music and the likelihood of a song becoming a hit. By analyzing cardiac activity using a wearable device, the researchers converted the data into measures of attention and emotion. Their machine-learning model achieved a remarkable 97% accuracy in predicting whether a song would be a hit or a flop. While the study offers potential implications for music production and curation, skeptics raise concerns about biases, ethical implications, and the reliability of fusing AI and brain data. Can Your Body's Response to Music Predict Hit Songs? A New AI Study Claims It Can - Scientific American

Collective Neuroscience: Brain Waves Align in Social Interaction

Brain Waves Synchronize when People Interact explores the fascinating phenomenon of brain wave synchronization during social interactions. Neuroscientists have discovered that when people converse, share experiences, or engage in joint activities, their brain waves synchronize. This collective neuroscience, as it's called, reveals that corresponding neurons in different brains fire simultaneously, creating matching patterns akin to dancers moving in sync. This synchronization extends to various brain regions and is associated with enhanced learning, enjoyment, and social bonds. Scientists are delving deeper into this field to understand the benefits and implications of brain wave synchrony in social behavior.

AI and Diabetes Management

To revolutionize the management of type 1 diabetes, researchers are exploring the potential of artificial intelligence (AI). Scientists developed a machine learning algorithm that can assist in insulin delivery for diabetes patients. Using offline reinforcement learning and virtual patient simulations, the AI algorithm achieved comparable dosing accuracy to commercial controllers but with significantly reduced training time. Although regulatory approval and real-world implementation remain, AI-powered diabetes technology could offer new hope for individuals living with the condition. Managing Type 1 Diabetes Is Tricky. Can AI Help?

048 - Mindfulishness, Alzheimer's and the Microbiome, VR Forest Bathing - HealthHippieMD Week In Revie

Alzheimer's and the Microbiome

In a groundbreaking study, researchers have discovered that alterations in the human gut microbiome can precede the cognitive declines associated with Alzheimer's disease. The study, led by experts in the gut microbiome and Alzheimer's research, found distinct differences in the gut bacteria of individuals in the preclinical stages of Alzheimer's, even before any visible symptoms emerge. The findings raise the possibility of using stool sample analysis to detect early risk for Alzheimer's, enabling earlier interventions to slow or halt its progression. Further research aims to determine if targeted dietary changes or probiotic treatments can effectively modify the gut microbiome and delay Alzheimer's development. Changes in Human Microbiome Precede Alzheimer's Cognitive Declines

Mindfulishness: Are Meditation Apps a Distraction Trap?

In the thought-provoking article, Your Phone Is the Wrong Place to Go for Mindfulness, the author explores the paradoxical nature of meditation apps and their relationship with smartphones. While mindfulness apps offer convenient access to meditation practices and promise to bring peace of mind, they also contribute to the ever-present distraction of smartphones. The article questions the effectiveness of using these apps on a device that is notorious for causing unfocus and stress. It highlights the need for mindful choices in our phone usage and suggests that true mindfulness may lie in disconnecting from the screen altogether.

When is Anxiety a Problem?

Anxiety disorders affect approximately 1 in 5 American adults. Understanding when anxiety becomes problematic is crucial. While anxiety can serve as a protective alarm system, persistent worry and interference with daily life may signal the need for evaluation and treatment. Dr. Petros Levounis, President of the American Psychiatric Association, sheds light on recognizing anxiety's red flags and the available treatments. Notably, the article also addresses the omission of older adults from the screening recommendations and emphasizes the importance of discussing emotional concerns with healthcare providers. When Is Anxiety a Health Problem? What to Know About New Screening Guidelines - The New York Times (gift article)

Unraveling Statins

Researchers have uncovered the long-standing puzzle surrounding the muscle-related side effects of statins, America's most popular drug for managing cholesterol. While investigating the genetic causes of limb-girdle muscle dystrophy, two independent groups of scientists unexpectedly identified mutations in the gene encoding the HMG-CoA reductase enzyme—the same enzyme statins inhibit to reduce cholesterol production. The discovery sheds light on the connection between a rare genetic disease and statins' common muscle-related side effects, offering potential insights for targeted treatments and improving the lives of severely affected patients. The Gene That Explains Statins' Most Puzzling Side Effect - The Atlantic

Forest Bathing in VR

Scientists are studying whether computer-generated forests have the same effect on health and well-being that natural forests do. "Forest bathing" might work in virtual reality too | MIT Technology Review

Dark Side of the Rainbow

In Pink Floyd, 'The Wizard of Oz' and Me, (gift article) a journalist shares his connection to the phenomenon that occurs when Pink Floyd's album "The Dark Side of the Moon" is played in sync with the movie "The Wizard of Oz." The article delves into the strange and surreal coincidences that arise from this synchronization and explores the journalist's role in popularizing the concept through his early internet presence. The story reflects on the cultural impact of this unique pairing and the enduring intrigue it continues to evoke.

Virtual Tours of the NIH

Are you curious about the history and footprint of the National Institutes of Health? You can now take a virtual tour: Virtual Tour | National Institutes of Health (NIH)

Canine Clinical Trials

Dog cancer research is helping drug development for humans and canines (gift article) is about driving advancements in the development of cancer drugs for both humans and canines. Comparative oncology, the study of cancers in companion animals, offers insights into human treatments and has gained momentum due to the high failure rate of cancer clinical trials using mouse models. Studying dogs provides advantages such as shared environmental factors, cleaner data, and easier data sharing, leading to potential breakthroughs in cancer treatment for both species.

The Brain as a Prediction Engine

"For as long as we've studied human cognition, we've believed that our senses give us direct access to the world. We see what's there—or so the thinking goes. But discoveries in neuroscience and psychology have turned this assumption on its head. What if rather than perceiving reality passively, your mind actively predicts it?" I just bought the book The Experience Machine: How Our Minds Predict and Shape Reality.

Trauma Hijacks the Prediction Algorithms of the Brain

The neuroscience of trauma is an interesting video featuring Dr. Lisa Feldman Barrett, who contends that trauma alters the prediction algorithms of the brain.

Anti-Prosopagnosiacs: Human Super-Recognizers Outshine AI in Facial Recognition

Current facial recognition technology has error rates ranging from 48 to 62 percent. To address this issue, police forces in London, Berlin, and Queensland have enlisted super-recognizers help—individuals with an innate talent for recognizing unfamiliar faces. Studies show that these human experts excel in challenging scenarios where AI falls short, such as low-resolution images or crowded environments. However, racial bias remains a challenge even for super-recognizers. Researchers aim to identify exceptional talents and uncover the secrets behind their extraordinary face recognition abilities. Police Are Using Human Super-Recognizers to Replace Facial Recognition Algorithms in Some Contexts.

End the Tyranny of Processed Food

"Anyone who's struggling with [food-related disease] as an individual should take their guilt and shame and transfer it outwardly to the corporations that are feeding us these addictive substances, to the governments doing nothing about it, and to the physicians and the social media personalities who keep telling us that this stuff is healthy. We must end the conflict of interest between the industry, politicians, doctors, and scientists. Only then can we tackle the problem." An opinion piece about the role of processed food in today's society. I agree with most, except for the part about physicians conspiring. The actual problem with physicians is a lack of understanding. It's Time to End the Tyranny of Ultra-Processed Food

Aspartame to be Declared Carcinogenic by WHO

The World Health Organization will reportedly categorize Aspartame/Nutrasweet as potentially carcinogenic. Aspartame: Key ingredient in Diet Coke set to be declared 'possible cancer risk' by WHO I also learned of a study last year (in mice) where aspartame increased anxiety and fear processing across generations.Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala

047 - Quiet Cravings, Post-Truth World, and Microbiome/Melanoma - HealthHippieMD Week In Review

Aging Time Warp

In I'm 53 years old. I'm 36 in my head, Jennifer Senior delves into the mysterious phenomenon of feeling younger than one's actual age. Drawing from various studies, Senior reveals that adults over 40 tend to perceive themselves as approximately 20 percent younger. The discrepancy between chronological and internal age can be attributed to various factors, including a sense of optimism and the reminiscence bump. Senior highlights the cultural and societal influences on subjective age, ultimately suggesting that feeling younger can positively affect health and well-being.

Countering Amygdala Hijacking

Conflict is inevitable in human relationships, but it doesn't have to be destructive. In the article, 6 steps to manage conflict with emotional intelligence,, the importance of emotional intelligence in handling conflict is highlighted. The author explains the concept of "amygdala hijacking," where our emotional responses take over during disputes, and offers strategies to counteract this effect. The six methods include:

• Understanding your conflict style.
• Identifying the core issues.
• Practicing self-regulation and calmness.
• Avoiding destructive communication habits.
• Fostering appreciation and empathy.
• Developing these skills through practice.

By employing these strategies, individuals can transform conflicts into opportunities for growth and deeper connections.

Beyond B.M.I.

The American Medical Association (A.M.A.) has acknowledged the limitations and potential harm of relying solely on body mass index (B.M.I.) to measure weight and health. The A.M.A. recognizes the historical exclusion and racial bias associated with B.M.I in a new policy. The recommendation encourages doctors to consider additional factors such as visceral fat, body adiposity index, body composition, and genetic/metabolic factors when assessing a patient's health. While B.M.I. may have its uses at a population level, the policy signifies a shift towards a more holistic approach to patient care, emphasizing the need to move beyond B.M.I. as a sole determinant of health. B.M.I. Alone Is Not Enough to Assess Health, American Medical Association says - The New York Times (gift article)

A.I. and a "Post-Truth" World

"A.I. will make it easier to produce disinformation—from fake images to deepfakes to fake news. That will affect people's trust as they're scrolling on social media" Wired had an interesting (dystopian) article on how A.I. might influence humanity. It's not pretty. Humans Aren't Mentally Ready for an AI-Saturated' Post-Truth World' | WIRED

Combatting Chemo Brain

"Chemo brain," a condition characterized by cognitive impairment and memory loss, affects many cancer patients during and after treatment. The causes and persistence of symptoms remain unclear. A multi-pronged approach is recommended to alleviate the chemo brain, including exercise, cognitive behavioral therapy, prioritizing sleep, practicing mindfulness, and potentially exploring psychostimulant medications. While no FDA-approved medicines for chemobrain exist yet, promising research on repurposing drugs initially used for other conditions offers hope for future solutions. Cognitive behavioral therapy may help ease 'chemo brain' - The Washington Post (gift article)

Anxiety Screening During Routine Healthcare

In response to the growing mental health crisis, primary care providers in the United States are encouraged to incorporate anxiety screenings into routine checkups. The U.S. Preventive Services Task Force has published new guidelines recommending that asymptomatic adults, including pregnant and postpartum individuals aged 19 to 64, be screened for anxiety disorders. The aim is to identify and treat anxiety disorders earlier, improving patient outcomes. However, concerns about the burden on an already overburdened mental healthcare system and the potential overdiagnosis of anxiety disorders in communities of color have been raised. Anxiety screening for adults under 65 now recommended at health checkups - The Washington Post (gift article)

Quieting the Cravings

In the article, What Is 'Food Noise'? How Ozempic Quiets Obsessive Thinking About Food - The New York Times (gift article) the New York Times explores the intriguing phenomenon of individuals experiencing diminished "food noise" after taking medications like Ozempic and Wegovy. "Food noise" refers to the constant preoccupation with food and cravings that some people struggle with. The active ingredient in these drugs, semaglutide, affects appetite-regulating areas in the brain and promotes a feeling of fullness. Through interviews and social media stories, the article highlights the relief and freedom reported by individuals who have successfully silenced their "food noise" with these medications.

100 Places to See AFTER You Die

The book 100 Places to See After You Die: A Travel Guide to the Afterlife "surveys ideas from around the world about what happens to us after we die. It's written as a travel guide, with an eclectic mix of 100 accounts, ranging from mythology and religion to ideas floated in books, movies, and T.V. shows." I'm going to check this one out. Ken Jennings visits the afterlife in '100 Places to See After You Die' - The Washington Post (gift article)

Melanoma and the Microbiome

Jamie Rettinger, the first person to undergo a fecal transplant to treat melanoma, shares his remarkable journey. Jamie's cancer spread after being misdiagnosed and mistreated, leaving him with limited treatment options. The experimental approach of fecal transplant, aimed at restoring beneficial bacteria in the gut, showed promising results. The transplant engrafted successfully, and Jamie's body responded to subsequent immunotherapy treatment, leading to the shrinking of melanoma signs. This groundbreaking research offers hope for improved melanoma treatments and emphasizes the potential role of the gut microbiome in shaping immune responses in cancer therapy and beyond. Man who got the first fecal transplant to cure melanoma shares his experience.

046 - Holobionts, Embracing Death, and the Moral Crisis of Physicians - HealthHippieMD Week In Review

Embrace Death for a Happier Life

Contemplating mortality may seem grim, but it is critical to a fulfilling existence. Drawing inspiration from Randy Pausch's remarkable Last Lecture, experts argue that acknowledging our finite existence enhances happiness. Avoiding thoughts of death leads to regret and postponing meaningful experiences. By embracing the reality of death, we make wiser choices, cherish relationships, and appreciate life's fleeting moments. Deliberately confronting mortality cultivates positive thinking and clarity, enabling us to live each day to the fullest. Think About Your Death and Live Better - The Atlantic

Taurine: a Longer Life or Just Bull?

A recent study in the journal Science suggests that taurine, a common amino acid, may be essential to anti-aging and longevity. Researchers discovered that taurine levels decline as organisms age, leading to tissue damage. However, supplementing taurine in the diets of worms, mice, and monkeys extended their lifespans and reversed age-related damage in their muscles, bones, and brains. More research is needed.Can Taurine, Found in Energy Drinks, Slow Down Aging? - The New York Times

Bots with Bedside Manner

In the article, Doctors Are Using ChatGPT to Improve How They Talk to Patients - The New York Times (gift article) the unexpected use of artificial intelligence (AI) chatbot ChatGPT by doctors is explored. While AI models like ChatGPT have the potential to assist with mundane tasks and improve efficiency, doctors have discovered their value in enhancing compassionate communication with patients. (Thanks, NextDraft)

We Are Multitudes: The Rise of Holobionts in Biology

In a paradigm shift for biology, the concept of "holobionts" is gaining recognition, emphasizing the interconnectedness of animals, plants, and their microbiota. The Leverhulme Centre for the Holobiont studies insects, amphibians, and plants to understand the symbiotic relationships within these organisms. Holobionts challenge the notion of a monogenic individual, highlighting the importance of the microbiome in evolution, health, and even agriculture. By unraveling the intricacies of holobionts, scientists are uncovering new insights into the world of multi-organismal biology. The idea of "holobionts" represents a paradigm shift in biology.

A New Beatles Song, Thanks to AI

The Beatles are going to release a new song later this year. Paul McCartney said he used technology to 'extricate' John Lennon's voice from an old demo and complete a decades-old piece. I can't wait. AI used to create new and final Beatles song, says Paul McCartney | The Guardian

The Military Method for Falling Asleep Quickly

A brief article with a method used by the U.S. Army to promote sleep in the worst conditions: The 5-step "military method" for falling asleep in minutes.

Sound Check: Noise and Health

"Chronic noise exposure is not just a nuisance, scientists say. It's a health risk." The article Are You Exposed to Too Much Noise? Here's How to Check. - The New York Times (gift article) explores the detrimental effects of chronic noise exposure on both hearing and cardiovascular health. As noise levels continue to rise, the risks of cardiovascular disease increase. The article provides resources for measuring noise exposure, such as an online noise map and the NIOSH Sound Level Meter app. It also offers tips for protecting oneself. By understanding and managing noise exposure, individuals can safeguard their well-being.

The Moral Crisis of American Doctors

The article, The Moral Crisis of America's Doctors - The New York Times (gift article), about the corporatization of medicine, spoke deeply to me. A must read.....

Distract to Connect

New research suggests that shared distraction can be a more effective way to foster genuine connections in a world obsessed with constant attention. Engaging in activities that divert focus from ourselves, such as physical exercise or exploring the environment, enhances social connectedness and creative thinking. By embracing distractions and incorporating them into our interactions, whether online or in person, we can strengthen relationships and enjoy more enriching conversations. Embrace Distraction. Your Friends Will Thank You. - The Atlantic

NCCIH Free Online Education

The National Center for Complementary and Integrative Medicine (NCCIH) has an expanding library of free educational seminars on the science behind complementary and integrative approaches: NCCIH Online Continuing Education Series.

Going the Extra Mile

In the article, Overtraining syndrome: How much exercise is too much,, Slate explores the dark side of endurance running and the potential for it to become a form of self-harm. While exercise is widely recognized for its physical and mental health benefits, pushing the boundaries can have detrimental effects. The article delves into personal stories of individuals addicted to pain and extreme physical challenges, highlighting the need to recognize one's limits and prioritize overall well-being. The author emphasizes the importance of finding a balance between perseverance and excess in the pursuit of athletic achievements.

How To Exercise When It's Humid

Humidity is ratcheting up here in North Carolina. The New York Times had a piece on exercising in humid weather: Tips for Exercising in Humidity.

045 - Dying Brains, Frenemies, and the Physiology of Hangry - HealthHippieMD Week In Review

Flavanols Combat Memory Loss in Aging Adults

A new study reveals that flavanols, nutrients found in select fruits and vegetables, are crucial in mitigating age-related memory decline. The research demonstrates a positive correlation between flavanol intake and memory test scores among older adults. Notably, individuals over 60 with low-flavanol diets experienced significant memory improvement after reintroducing these dietary components. This study supports the emerging understanding that specific nutrients are essential for maintaining optimal brain health as we age. By highlighting the power of flavanols, the research offers potential avenues for improving cognitive function in older adults and underscores the importance of a flavanol-rich diet or supplements. Memory Boosting Power of Flavanols in Aging Adults

Gut Check

Scientists have discovered the mechanism behind how chronic stress can lead to gut inflammation. Signals originating in the brain reach gut nerve cells, triggering the release of inflammatory chemicals. The study, The enteric nervous system relays psychological stress to intestinal inflammation glucocorticoids act on gut neurons and glial cells, which then activate immune cells. These immune cells release molecules that cause painful bowel inflammation. The findings suggest that managing stress levels could significantly impact the effectiveness of treatments for inflammatory bowel disease (IBD). The research opens possibilities for targeting the brain-to-gut signaling pathway for new therapies. Chronic stress can inflame the gut — now scientists know why

Frenemies Take a Toll

According to psychologists, ambivalent relationships, known as frenemies, which combine positive and negative aspects, can be more detrimental to health than purely negative relationships. Research reveals that interacting with individuals who evoke mixed feelings can raise blood pressure and lead to negative physical symptoms. Even a single ambivalent interaction can have adverse effects on well-being. Unpredictability increases pain from unpleasant interactions, and rumination contributes to the negative impact of such relationships. Recognizing the harmful effects of frenemies is important for maintaining overall health and well-being. Opinion | Ambivalent Relationships May Be Hazardous to Your Health. (gift article)

The Neuroscience of Hangry

Neuroscientists have discovered a cluster of cells called AgRP neurons that stimulate appetite and play a vital role in the infamous "hangry" feeling. These cells near the brain's blood supply receive signals from the stomach and fat tissue, influencing our hunger levels. By manipulating AgRP neuron activity in mice, researchers have identified how they trigger food-seeking behavior and respond to the presence of nutrients. This breakthrough could lead to new therapies for eating disorders like anorexia and overeating. By understanding and controlling the hangry feeling, scientists hope to revolutionize our ability to manage our diets effectively. Neuroscientists May Have Found the Part of Your Brain That Makes You Hangry

Electrical Activity Surges in the Dying Brain

A new study reveals that dying brains experience a surge of electrical activity, challenging the assumption that brain activity decreases during dying. Researchers monitored four comatose patients who died in a neurointensive care unit and observed a surge of neurophysiological activity in regions associated with conscious processing. This surge included increased synchronization and connectivity between different brain regions. While the study doesn't directly explain near-death experiences, it suggests that the observed brain activity pattern may contribute to the vivid perceptions reported during such experiences, prompting further investigation into the nature of human consciousness. Scientists monitored four dying patients' brains. Here's what they saw . In the late 2000s, David Auyong and I observed the same phenomenon while on call: Processed electroencephalogram during donation after cardiac death.

Biochemistry of Psychedelics, BDNF, and Neuroplasticity

Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience reveals that LSD and magic mushrooms dramatically rewire the brain, offering new possibilities for treating depression. The research conducted by an international team of scientists from the University of Helsinki shows that, at least in a test tube, these psychedelics bind to a protein called receptor tyrosine kinase beta (TrkB), which activates brain-derived neurotrophic factor (BDNF). BDNF plays a crucial role in neuron growth and development. This discovery paved the way for developing safer and more effective treatments for mental health disorders. LSD and Magic Mushrooms Dramatically Rewire the Brain, New Study Reveals.

AIHits (Generative AI Music and Podcasts)

"What makes pop work is that it's always changing and always responding. This is just a feedback loop between systems." AI is having a profound effect on artistic expression in music. Now there's a website to listen to. AI Could Usher in a New Era of Music. Will It Suck?

+The Generative AI gold rush is on in the podcasting space, too, as if the genre wasn't already overcrowded: Generative AI Podcasts Are Here. Prepare to Be Bored.

The Evolutionary Significance of Dreaming

"REM [sleep] has been crucial to human creativity."The evolutionary significance of dreaming is an interesting video on BigThink.

External Stressors Affect Cancer Mortality

Surprise, surprise! Higher allostatic load, a quantitive measure of the cumulative physiological damage from stress, is associated with worse cancer outcomes: Evidence Emerges Showing External Stressors Adversely Affect Cancer Outcomes

Sucralose-Genotoxic?

At least in test tubes, new evidence shows that Sucralose (Splenda) can disrupt DNA. "It's time to revisit the safety and regulatory status of sucralose because the evidence is mounting that it carries significant risks." Sucralose Damages DNA, Linked to Leaky Gut: Study (thanks, Diana!)